دانلود مقالات ISI درباره Nf-Κb + ترجمه فارسی

Teleost-specific TLR25 identified from Schizothorax prenanti may recognize bacterial/viral components and activate NF-κB and type I IFNs signaling pathways

Keywords: TLR25; LPS; Poly(I:C); NF-κB; Type I IFNs; Signaling pathway;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Kafirin from Sorghum bicolor inhibition of inflammation in THP-1 human macrophages is associated with reduction of intracellular reactive oxygen species

Keywords: Cytokines; Inflammation; Kafirin; NF-κB; Reactive oxygen species; Sorghum;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Ethnopharmacology, phytochemistry, and pharmacology of Chinese Salvia species: A review

Keywords: ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AST; aspartate transaminase; CAT; catalase; CCL4; carbon tetrachloride; CK; casein kinase; DMN; dimethylnitrosamine; DPPH; 2,2-diphenyl-1-picrylhydrazyl; GSH; glutathione; HPRI; hepa

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Curcumin ameliorates the in vitro efficacy of carfilzomib in human multiple myeloma U266 cells targeting p53 and NF-κB pathways

Keywords: Myeloma; Curcumin; Carfilzomib; NF-κB; p53; Proteasome inhibitor;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Sesquiterpene lactones from Ambrosia arborescens Mill. inhibit pro-inflammatory cytokine expression and modulate NF-κB signaling in human skin cells

Keywords: NSAID; Pseudoguaianolides; NF-κB; Inflammation; Dermal fibroblasts; Andean medicine; SL; sesquiterpene lactone; RT-PCR; reverse transcription-polymerase chain reaction; DMSO; dimethyl sulfoxide; NF-κB; nuclear factor kappa-light-chain-enhancer of activa

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-κB pathway

Keywords: Rhynchosia minima root; Polysaccharide; Immunomodulation; Toll-like receptor 4; NF-κB;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases

Keywords: LOX-1; Endothelial dysfunction; Atherosclerosis; Pharmacological therapy: microRNAs; ACE; angiotensin converting enzyme; Ang II; Angiotensin II; AT1R; angiotensin II receptor type 1; CCB; calcium channel blocker; CRP; C-reactive protein; eNOS; endothelial

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors

Keywords: AP-1; activator protein 1; CNI; calcineurin inhibitor(s); ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ERK; extracellular signal regulated kinase; FKBP; FK506 binding protein; JNK; Jun N-terminal kinase; LAP; latency-associated pr

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Regulatory role of IKKɑ in myocardial ischemia/reperfusion injury by the determination of M1 versus M2 polarization of macrophages

Keywords: IKKɑ; Myocardial ischemia and reperfusion injury; Macrophages polarization; NF-κB; MEK1/2/ERK1/2;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer

Keywords: FXR; Obeticholic Acid; S-Adenosylmethionine; Ursodeoxycholic Acid; AP-1; activator protein-1; ARE; antioxidant response element; BDL; bile duct ligation; BrdU; 5-bromo-2'deoxyuridine; CCA; cholangiocarcinoma; FXR; farnesoid X receptor; GSH; reduced glut

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Vitamin C for the treatment of sepsis: The scientific rationale

Keywords: ACTH; adrenocorticotropic hormone; BH4; tetrahydrobiopterin; CRRT; continuous renal replacement therapy; GR; glucocorticoid receptor; GULO; l-gulono-γ-lactone oxidase; G6PD; glucose-6-phosphate deficiency; HMGB1; high mobility group box 1; HOCL; hypo-chl

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Methylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models

Keywords: Epilepsy; Drug discovery; Methylated flavonoids; Naringenin; Zebrafish; Mouse; AED; anti-epileptogenic drug; ASD; anti-seizure drug; cLogP; calculated LogP; dpf; days post-fertilization; DMSO; dimethyl sulfoxide; GABA; γ-aminobutyric acid; IL-1β; interl

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

A constitutively-active IKK-complex at the axon initial segment

Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Suppression of Pax2 Attenuates Allodynia and Hyperalgesia through ET-1-ETAR-NFAT5 Signaling in a Rat Model of Neuropathic Pain

Keywords: ET-1; Endothelin-1; ETAR; endothelin receptor type A; ETBR; Endothelin receptor type B; FISH; fluorescence in situ hybridization; MAPK; mitogen-activated protein kinases; NFAT5; nuclear factor of activated T-cells 5; NF-κB; nuclear factor-kappa B; Pax2;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation

Keywords: ABAH; 4-aminobenzoic acid hydrazide; ANCA; anti-neutrophil cytoplasmic antibody; ATP6; mitochondrial membrane ATP synthase; CYTB; cytochrome b; ETs; extracellular traps; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; granulocyte-macrophage colon

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-osteoclastic effect of caffeic acid phenethyl ester in murine macrophages depends upon the suppression of superoxide anion production through the prevention of an active-Nox1 complex formation

Keywords: CAPE; caffeic acid phenethyl ester; RANKL; receptor activator of nuclear factor-κB ligand; TRAP; tartrate-resistant acid phosphatase; ROS; reactive oxygen species; Nox1; NADPH (nicotinamide adenine dinucleotide phosphate) oxidase 1; NF-κB; nuclear facto

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27

Keywords: Sec6; p38 MAPK; MK2; HSP27; MAPK; Mitogen-activated protein kinases; MAP3K; MAPK kinase kinase; MAP2K; MAPK kinase; TAK1; TGFβ-activated kinase 1; ASK1; apoptosis signal-regulating kinase 1; MLK; mixed-lineage kinase; CREB; cAMP response element binding

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling

Keywords: BACE1; CREB; insulin resistance; NF-κB; palmitate; PGC-1α; sAPPβ;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

ROS signalling in the biology of cancer

Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Synaptically Localized Transcriptional Regulators in Memory Formation

Keywords: LTP; long-term potentiation; NMDA; N-methyl-d-aspartate acid; Ser133; serine amino acid 133; memory; nucleocytoplasmic shuttling; transcription; CREB; CRTC1; HDAC4; NF-κB;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways

Keywords: Phellinus linteuspolysaccharide (PLP); Inflammation; Colitis; MAPK; NF-κB; AP-1; PPAR;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Formation and biological targets of botanical o-quinones

Keywords: Quinones; P450; Bioactivation; Botanicals; Chemoprevention; Carcinogen; ARE; antioxidant response element; BiP; binding immunoglobin protein; COX-2; cyclooxygenase-2; JNK; c-Jun N-terminal kinase; EGCG; (−)-epigallocatechin gallate; GST; glutathione-S-t

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of ABCG2 by nuclear factor kappa B affects the sensitivity of human lung adenocarcinoma A549 cells to arsenic trioxide

Keywords: Arsenic trioxide; ABCG2; NF-κB; Drug sensitivity;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-κB activity

Keywords: Diclofenac; Acute kidney injury; PDTC; Oxidative stress; Cytokine; NF-κB;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphosulindac is efficacious in an improved concanavalin A-based rabbit model of chronic dry eye disease

Keywords: BSA; bovine serum albumin; Con A; concanavalin A; DED; dry eye disease; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; IC50; half-maximal inhibitory concentration; IL-1β;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression

Keywords: Parthenolide; Temozolomide; Glioma; NF-κB; MGMT;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo

Keywords: PPI; polyphyllin I; CRPC; castration-resistant prostate cancer; EZH2; Zeste homolog 2; DNMT1; DNA methyltransferase 1; HOTAIR; HOX transcript antisense RNA; ADT; androgen deprivation therapy; NF-κB; nuclear factor-kappaB; lncRNA; Long non-coding RNA; DNM

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity

Keywords: AICAR; 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside; ATMs; adipose tissue macrophages; CC; compound C; Ctrl; control; ERK1/2; p44/42 mitogen-activated protein kinase; FNDC5; fibronectin type III domain-containing protein 5; GTT; glucose tolerance

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

NF-κB signaling is key in the wound healing processes of silk fibroin

Keywords: Silk fibroin; NF-κB; Wound healing; NIH3T3 cells; Mechanism;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Kaempferol 7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages

Keywords: Kaempferol 7-O-β-D-glucoside; NF-κB; AP-1; JAK-STAT; RAW 264.7 macrophages;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Human-based systems: Mechanistic NASH modelling just around the corner?

Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner

Keywords: Ab; antibody; AhR; aryl hydrocarbon receptor; APC; antigen-presenting cell; ARNT; AhR nuclear translocator; BaP; benzo(a)pyrene; BMDCs; bone-marrow derived dendritic cells; BMMs; bone-marrow derived macrophages; CD; cluster of differentiation; CYP 450; cy

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of anti-oxidant Nrf2 signaling by enone analogues of curcumin

Keywords: Nrf2 activation; Pyridone; Enone; Aldol condensation; Nrf2; nuclear factor erythroid 2 related factor 2; CNS; central nervous system; Keap1; Kelch-like ECH associated protein 1; NF-κB; nuclear factor kappa-light-chain enhancer of activated B cells; Maf;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

N-phenylsulfonyl-3,5-bis(arylidene)-4-piperidone derivatives as activation NF-κB inhibitors in hepatic carcinoma cell lines

Keywords: 3,5-bis(arylidene)-4-piperidone; Cytotoxicity; Anti-inflammatory activity; NF-κB;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Combined immunodeficiency and atopy caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11)

Keywords: Caspase activation and recruitment domain family member 11; combined immunodeficiency; hypogammaglobulinemia; nuclear factor κB; cytokine secretion; T-cell repertoire; T-cell mitogen and antigen responses; autoimmunity; asthma; eczema and food allergies;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice

Keywords: Metformin; Alzheimer disease; Neuroinflammation; Neurogenesis; AMPK; mTOR; NF-κB;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effect of Juglans regia L. against ultraviolet B radiation induced inflammatory responses in human epidermal keratinocytes

Keywords: J. regia L.; Antioxidant; Inflammation; SPF; UVB radiation; Skin cells; UVB; ROS, reactive oxygen species; MAPK; mitogen-activated protein kinases; COX-2; cyclooxygenase-2; TNF-α; Tumor necrosis factor-α; IL-6; interleukin-6; NF-κB; nuclear factor kapp

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocyte elevated gene-1 is a novel regulator of astrogliosis and excitatory amino acid transporter-2 via interplaying with nuclear factor-κB signaling in astrocytes from amyotrophic lateral sclerosis mouse model with hSOD1G93A mutation

Keywords: ALS; Amyotrophic lateral sclerosis; AEG-1; Astrocyte elevated gene-1; ACM; astrocyte-conditioned medium; CBP; CREB-binding protein; COX-2; Cyclooxygenase-2; DMSO; dimethyl sulfoxide; DL-NBP; DL-3-n-butylphthalide; DMEM; Dulbecco modified Eagle medium; EAA

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling

Keywords: Smac mimetics; Microarray; Breast cancer; Cell death; IAP proteins; Cytokines; AP-1; activator protein 1; BIR; baculovirus IAP repeat; cIAP; cellular IAP; DEG; differential regulated gene; FADD; FAS-associated protein with death domain; FCS; fetal calf se

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-Inflammatory Therapy With Canakinumab for the Prevention and Management of Diabetes

Keywords: cardiovascular disease; diabetes; inflammation; randomized trial; CI; confidence interval; HbA1c; glycosylated hemoglobin; HR; hazard ratio; hsCRP; high-sensitivity C-reactive protein; IL; interleukin; IQR; interquartile range; NF-κB; nuclear factor kapp

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Intracellular TLR22 acts as an inflammation equalizer via suppression of NF-κB and selective activation of MAPK pathway in fish

Keywords: Intracellular TLRs; TLR22; NF-κB; MAPK; Accessory molecules;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-inflammatory effects of Zhishi and Zhiqiao revealed by network pharmacology integrated with molecular mechanism and metabolomics studies

Keywords: Zhishi; Zhiqiao; Network pharmacology; Anti-inflammatory mechanism; Metabolomics; CRP; C-reactive protein; QC-markers; quality control markers; MAPK; mitogen-activated protein kinase; ATP; adenosine triphosphate; AA; arachidonic acid; LPS; lipopolysacchar

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Multifunctional molecule ERp57: From cancer to neurodegenerative diseases

Keywords: 1α,25(OH)2D3; 1,25-dihydroxyvitamin D3; ADAM10; a disintegrin and metalloproteinase 10; AIF; apoptosis-inducing factor; AP-1; activator protein 1; ATRA; all-trans retinoic acid; BMP-2; bone morphogenic protein 2; CLNX; calnexin; CRT; calreticulin; ECM; e

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of perfluorooctane sulphonate-induced Kupffer cell activation on hepatocyte proliferation through the NF-κB/TNF-α/IL-6-dependent pathway

Keywords: PFOS; Kupffer cells; Inflammation; Hepatocyte proliferation; NF-κB/ TNF-?/IL-6; ALT; alanine aminotransferase; AST; aspartate transaminase; APAP; acetaminophen; CCl4; carbon tetrachloride; CHE; cholinesterase; CM; conditioned media; CyD1; Cyclin D1; DAPI

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome

Keywords: IFN; interferon; ISGs; IFNstimulated genes; HCV; hepatitis C virus; IL-10; interleukin-10; PDL-1; programmed death-ligand 1; LCMV; lymphocytic choriomeningitis virus; IFNAR; IFNA receptor; IRFs; IFN regulatory factors; pDCs; plasmacytoid dendritic cells;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury

Keywords: ERK1/2; extracellular signal-regulated kinase 1/2; mTOR; mechanistic target of rapamycin; Stat3; signal transducer and activator of transcription 3; TBI; traumatic brain injury; ALI; acute lung injury; HMGB1; high-mobility group box protein 1; 3-MA; 3‑m

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Cross-talk between insulin signalling and LPS responses in mouse macrophages

Keywords: Il-10; Tnf-α; NF-κB; ERK1/2; Macrophage; Insulin;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Zafirlukast and vincamine ameliorate tamoxifen-induced oxidative stress and inflammation: Role of the JNK/ERK pathway

Keywords: Liver injury; Tamoxifen; Zafirlukast; Vincamine; JNK/ERK pathway; NF-κB; Caspases-3;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Ethnopharmacological uses, phytochemistry and pharmacology of genus Adiantum: A comprehensive review

Keywords: ABTS; 2, 2′azinobis (3-ethyl-benzothiozoline-6-sulfonic acid); ATP; adenosine triphosphate; BHT; butylated hydroxytoluene; CAT; catalase; CCl4; carbon tetrachloride; DPPH; 2,2-diphenyl-1-picrylhydrazyl; FA; flavonoids of Adiantum; FRAP; ferric reducing

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه