دانلود مقالات ISI درباره Nicotinamide N-Methyltransferase + ترجمه فارسی

Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ

Keywords: Nicotinamide N-methyltransferase; Activity-based profiling; Proteomics; Inhibitor; Cysteine; Covalent;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition

Keywords: 4-PP; 4-phenylpyridine; DMSO; dimethylsulphoxide; DV; dependent variable; hNNMT; recombinant human NNMT; IV; independent variable; kcat/Km; catalytic efficiency; MeNH; 2N-methylnorharman; MMP; mitochondrial membrane potential; MPP+; 1-methyl-4-phenylpyrid

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Keywords: Obesity; Therapeutics; Nicotinamide N-methyltransferase; Inhibitors; Weight loss;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Keywords: BSA; bovine serum albumin; Enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3; ESRD; end stage renal disease; FFA; free fatty acid; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxigenase-1; MCP-1; monocyte chemoattractant protein-1; 1-MNA; 1-methylnicoti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Fecal and urinary NMR-based metabolomics unveil an aging signature in mice

Keywords: 1MNA; 1-methylnicotinamide; AUROC; Area Under the ROC curve; DQ2; Discriminant Q2; LV; Latent Variable; MS; mass spectrometry; NMR; nuclear magnetic resonance; NNMT; nicotinamide N-methyltransferase; NMC; Number of Misclassification; PBS; phosphate buffer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Nicotinamide N-methyltransferase enhances the capacity of tumorigenesis associated with the promotion of cell cycle progression in human colorectal cancer cells

Keywords: Nicotinamide N-methyltransferase; Colorectal cancer; Cell cycle; Apoptosis; 1-Methylnicotinamide; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Single bout of endurance exercise increases NNMT activity in the liver and MNA concentration in plasma; the role of IL-6

Keywords: endurance exercise; interleukin-6; nicotinamide N-methyltransferase; 1-methylnicotinamide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Nicotinamide N-methyltransferase (NNMT) and 1-methylnicotinamide (MNA) in experimental hepatitis induced by concanavalin A in the mouse

Keywords: nicotinamide N-methyltransferase; 1-methylnicotinamide; concanavalin A; hepatits; BALB/c mice

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of nicotinamide N-methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis

Keywords: nicotinamide N-methyltransferase; 1-methylnicotinamide; atherosclerosis; vascular inflammation; ApoE/LDLR−/− miceMet-2PY, 1-methyl-2-pyridone-5-carboxamide; Met-4PY, 1-methyl-4-pyridone-5-carboxamide; MNA, 1-methylnicotinamide; NA, nicotinamide; NNMT, nic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

The relation between nicotinamide N-methyltransferase gene polymorphism and plasma homocysteine concentration in healthy Japanese men

Keywords: Homocysteine; Folate; Age; Nicotinamide N-methyltransferase; Methylenetetrahydrofolate reductase; Interaction;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه