Keywords: NMDA، N-methyl-d-aspartate; GLT-1, glutamate transporter 1; NAc, nucleus accumbens; PFC, prefrontal cortex; VTA, ventral tegmental area; nAChRs, nicotinic acetylcholine receptors; iGLURs, ionotropic glutamate receptors; NMDA, N-methyl-D-aspartate; AMPA, ά-amino-3-hydroxy-5-methyl-4-
مقالات ISI NMDA، N-methyl-d-aspartate (ترجمه نشده)
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Keywords: NMDA، N-methyl-d-aspartate; ANOVA-RM, repeated measures analysis of variance; LH, Lister Hooded rat; NMDA, N-methyl-D-aspartate; PCP, phencyclidineAntipsychotics; Phencyclidine; Rat strain; Schizophrenia; Spatial learning and memory; Water maze
Keywords: NMDA، N-methyl-d-aspartate; ALLO, Allopregnanolone; GABAA, γ-aminobutyric acid type A; NMDA, N-methyl-d-aspartate; SP, substance P; CGPR, calcitonin gene-related peptide; KOR, kappa opioid receptor; DOR, delta opioid receptor; MOR, mu opioid receptor; DHEA, dehydroepiandrosterone; D
Keywords: NMDA، N-methyl-d-aspartate; ANOVA, analysis of variance; DAPI, 4′,6-diamidino-2-phenylindole; FASDs, Fetal Alcohol Spectrum Disorders; GFAP, glial fibrillary acidic protein; IBA-1, ionized calcium-binding adapter molecule 1; NMDA, N-methyl-d-aspartate; NeuN, neuronal nuclei; P, post
Keywords: NMDA، N-methyl-d-aspartate; TBI, traumatic brain injury; CDC, Centers for Disease Control and Prevention; ED, emergency department; AHRQ, US Agency for Healthcare Research and Quality; NMDA, N-methyl-D-aspartate; DRS, disability rating scale; CSM, cerebral state monitoring; PTSD, po
Keywords: NMDA، N-methyl-d-aspartate; DHEA, dehydroepiandrosterone; DHEA-S, dehydroepiandrosterone sulfate; NMDA, N-methyl-d-aspartate; GABAA, γ-aminobutyric acid type A; TH, tyrosine hydroxylase; ADHD, attention-deficit hyperactivity disorder; NS, novelty seeking; HA, harm avoidance; RD, rew
Keywords: NMDA، N-methyl-d-aspartate; GI, gastrointestinal; SNP, single nucleotide polymorphisms; BDNF, brain-derived neurotrophic factor; NMDA, N-methyl-D-aspartate; AGA, anti-gliadin antibodiesGluten; Gut; Inflammation; Microbiota; Probiotics; Schizophrenia
Keywords: NMDA، N-methyl-d-aspartate; AUC, areas under the time-course curves; CNS, central nervous system; GLS1, phosphate-activated glutaminase type 1; NMDA, N-methyl-d-aspartate; WT, wild-typephosphate-activated glutaminase type 1; nociceptive tests; formalin; memantine; morphine
Keywords: NMDA، N-methyl-d-aspartate; 19; 25ATP, adenosine triphosphate; CPB, cardiopulmonary bypass; DHCA, deep hypothermic circulatory arrest; IQR, interquartile range; MAP, mean arterial pressure; NMDA, N-methyl-D-aspartate; POD, postoperative day; VGCC, voltage-gated calcium channel
Keywords: NMDA، N-methyl-d-aspartate; 26AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazole proprionate; CSF, cerebrospinal fluid; IVC, inferior vena cava; MEP, motor evoked potential; NMDA, N-methyl-d-aspartate; TAAA, thoracoabdominal aortic aneurysm
Keywords: NMDA، N-methyl-d-aspartate; GDH, glutamate dehydrogenase; DL-TBOA, DL-threo-β-benzyloxyaspartate; NMDA, N-methyl-d-aspartate; AMPA, 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; EAAT, excitatory amino-acid transportersFerritin; Apoferritin; Glutamate; Ambient level; Upta
Keywords: NMDA، N-methyl-d-aspartate; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; EOD, electric organ discharge; GluR2B, glutamate AMPAR subunit type 2B; NMDA, N-methyl-D-aspartate; PN, pacemaker nucleus; PPN, diencephalic pre-pacemaker; PPNc, diencephalic pre-pacemaker chirp
Keywords: NMDA، N-methyl-d-aspartate; ABR, auditory brainstem-evoked response; ANOVA, analysis of variance; BBN, broad band noise; CS, conditioned stimulus; CN, cochlear nucleus; GAD-67, glutamic-acid decarboxylase-67; LMM, linear mixed model; NMDA, N-methyl-d-aspartate; SPL, sound pressure l
Keywords: NMDA، N-methyl-d-aspartate; A1/2, half maximum absorbance; Amin, minimum absorbance; CCCP, carbonyl cyanide m-chlorophenyl hydrazone; CsA, cyclosporin A; DCF, dihydrodichlorofluorescein diacetate; ΔΨm, mitochondrial membrane potential; MK-801, dizocilpine; NMDA, N-methyl-d-aspartate
Keywords: NMDA، N-methyl-d-aspartate; DR, dorsal raphe; DMH, dorsomedial hypothalamus; GPCR, G protein coupled receptor; GABA, gamma amino butyric acid; LDT, laterodorsal tegmental nucleus; LC, locus coeruleus; LPC, lysophosphatydylcholine; NMDA, N-methyl-d-aspartate; NSCC, non-selective cati
Mystixin-7 mini-peptide protects ionotropic glutamatergic mechanisms against oxygen–glucose deprivation in vitro
Keywords: NMDA، N-methyl-d-aspartate; MTX, mystixin-7 mini-peptide; aCSF, artificial cerebrospinal fluid; LOT, lateral olfactory tract; FP, field potential; EPSP, excitatory postsynaptic potential; NMDA, N-methyl-d-aspartate; AMPA, [alpha]-amino-3-hydroxy-5-methyl-4-isoxazolepropionic; OGD, o
Arctigenin reduces neuronal responses in the somatosensory cortex via the inhibition of non-NMDA glutamate receptors
Keywords: NMDA، N-methyl-d-aspartate; Arctigenin; Ionotropic glutamate receptors; Evoked field potentials; Rat; Brain slices; In vivo experimentsAMPA, α-amino-3-hydroxy-5-methylisoxazole-4-propionate; NMDA, N-methyl-D-aspartate; S.E.M., standard error of means
Electrophysiological evidence showing muscarinic agonist–antagonist activities of N-desmethylclozapine using hippocampal excitatory and inhibitory neurons
Keywords: NMDA، N-methyl-d-aspartate; oxo-M, oxotremorine M; NDMC, N-desmethylclozapine; PLC, phospholipase C; NMDA, N-methyl-d-aspartate; EPSC, excitatory postsynaptic current; IPSC, inhibitory postsynaptic current; TTX, tetrodotoxinN-desmethylclozapine; Clozapine; Muscarinic agonist; Muscar
Agmatine inhibits nuclear factor-κB nuclear translocation in acute spinal cord compression injury rat model
Keywords: NMDA، N-methyl-d-aspartate; SCI, spinal cord injury; SCCI, spinal cord compression injury; NF-κB, nuclear factor kappa B; Agm, Agm; DL, decompression laminectomy; TNF- α, tumor necrosis factor-α; IL-6, interleukin-6; NMDA, N-methyl-D-aspartate; TAC, total antioxidant capacity; MDA,
Estimation of excitatory and inhibitory synaptic conductance variations in motoneurons during locomotor-like rhythmic activity
Keywords: NMDA، N-methyl-d-aspartate; 5-HT, 5-hydroxytryptamine; ACF, autocorrelation function; CNS, central nervous system; CPG, central pattern generator; MN, motoneuron; NMDA, N-methyl-d-aspartate; VR, ventral rootsynaptic conductance estimation; locomotion; spinal cord; central pattern ge
Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction
Keywords: NMDA، N-methyl-d-aspartate; CRTH2, chemoattractant receptor homologous molecule expressed on T helper type 2 cells; COX, cyclooxygenase; LPS, lipopolysaccharide; NMDA, N-methyl-d-aspartate; NORT, novel object recognition test; PVN, paraventricular nucleus; PC/RS, posterior cingulate
Memantine alters striatal plasticity inducing a shift of synaptic responses toward long-term depression
Keywords: NMDA، N-methyl-d-aspartate; Memantine; Striatum; Synaptic plasticity; LTP; LTD; NMDA receptor; D2 receptorSPNs, spiny projection neurons; LTP, long-term potentiation; LTD, long-term depression; NMDA, N-Methyl-d-Aspartate; HFS, high frequency stimulation; DA, dopamine; AD, Alzheimer'
Dizocilpine (MK-801) impairs learning in the active place avoidance task but has no effect on the performance during task/context alternation
Keywords: NMDA، N-methyl-d-aspartate; AAPA, active allothetic place avoidance; ANOVA, analysis of variance; i.p., intraperitoneal application; MWM, Morris water maze; NMDA, N-methyl-d-aspartate; S.E.M., standard error of the meanTask alternation; Context alternation; Active place avoidance; M
NMDA receptor activation regulates sociability by its effect on mTOR signaling activity
Keywords: NMDA، N-methyl-d-aspartate; TSC, Tuberous Sclerosis Complex; ASD, Autism spectrum disorder; mTORC1, Mammalian target of rapamycin complex 1; Rheb, Ras homolog enriched in brain; mTOR, Mammalian target of rapamycin; PTEN, Phosphatase and tensin homolog; NMDA, N-methyl-D-aspartate; ER
Memantine selectively blocks extrasynaptic NMDA receptors in rat substantia nigra dopamine neurons
Keywords: NMDA، N-methyl-d-aspartate; CNQX, 6-cyano-7-nitro-quinoxalone; EPSC, excitatory postsynaptic current; NMDA, N-methyl-d-aspartate; SNC, substantia nigra zona compacta; TTX, tetrodotoxinWhole-cell recording; Brain slice; MK-801; DQP-1105; Synaptic; Extrasynaptic
Sex-specific restoration of MK-801-induced sensorimotor gating deficit by environmental enrichment
Keywords: NMDA، N-methyl-d-aspartate; CON, control; EE, enriched environment; MK-801, (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate; MAM, methylazoxymethanol acetate; NMDA, N-methyl-d-aspartate; P, postnatal day; PACAP, pituitary adenylate cyclase-activating polypep
Methylmercury causes neuronal cell death through the suppression of the TrkA pathway: In vitro and in vivo effects of TrkA pathway activators
Keywords: NMDA، N-methyl-d-aspartate; MeHg, methylmercury; Trk, tropomyosin receptor kinase; NF-H, neurofilament triplet H; NMDA, N-methyl-d-aspartate; NGF, nerve growth factor; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl-2H-tetrazolium, inner salt); LDH, lac
Local group I mGluR antagonists reduce TMJ-evoked activity of trigeminal subnucleus caudalis neurons in female rats
Keywords: NMDA، N-methyl-d-aspartate; ANOVA, analysis of variance; ATP, adenosine triphosphate; ERs, estrogen receptors; HE, high-dose estradiol; LE, low-dose estradiol; mGluR, G protein-coupled metabotropic receptors; NMDA, N-methyl-d-aspartate; OvX, ovariectomized; PBS, phosphate-buffered s
Chronic sodium salicylate administration enhances population spike long-term potentiation following a combination of theta frequency primed-burst stimulation and the transient application of pentylenetetrazol in rat CA1 hippocampal neurons
Keywords: NMDA، N-methyl-d-aspartate; aCSF, artificial cerebrospinal fluid; CA1, cornus ammonis 1; fEPSP, field excitatory postsynaptic potential; GABA, gamma-amino butyric acid; LTD, long-term depression; LTP, long-term potentiation; NMDA, N-methyl-d-aspartate; PTZ, pentyleneterazol; PBs, pr
Local N-methyl-d-aspartate receptor antagonism in the prefrontal cortex attenuates spatial cognitive deficits induced by gonadectomy in adult male rats
Keywords: NMDA، N-methyl-d-aspartate; ANOVA, analysis of variance; APV, apv, D(−)-2-amino-5-phosphonopentanoic acid; BSM, bulbospongiosus muscle; CTRL, control; DA, dopamine; E, estradiol; GDX, gonadectomy; GLU, glutamate; MK801, dizolcilpine; NMDA, N-methyl-d-aspartate; NMDAR, N-methyl-d-asp
The role of TRPC6 in seizure susceptibility and seizure-related neuronal damage in the rat dentate gyrus
Keywords: NMDA، N-methyl-d-aspartate; DG, dentate gyrus; DGCs, dentate granule cells; fEPSP, field excitatory postsynaptic potential; GABA, γ-aminobutyric acid; GAD67, glutamate decarboxylase 67; IO, input–output; LIMK2, LIM kinase 2; NeuN, neuronal nuclear antigen; NMDA, N-methyl-d-aspartate
Uptake of a cyanotoxin, β-N-methylamino-l-alanine, by wheat (Triticum aestivum)
Keywords: NMDA، N-methyl-d-aspartate; BMAA, β-N-methylamino-l-alanine; ALS/PDC, amyotrophic lateral sclerosis/parkinsonism-dementia complex; NMDA, N-methyl-d-aspartate; TCA, trichloroacetic acid; LOD, limit of detection; FW, fresh weight; DW, dry weightβ-N-methylamino-l-alanine; Cyanobacteria
NMDA and AMPA receptors in the anterior cingulate cortex mediates visceral pain in visceral hypersensitivity rats
Keywords: NMDA، N-methyl-d-aspartate; VH, visceral hypersensitivity; ACC, anterior cingulate cortex; NMDA, N-methyl-d-aspartate; AMPA, 3-hydroxy-5-methyl-4-isoxazolepropionate; CRD, colorectal distension; AWR, abdominal withdrawal reflex; H&E staining, haematoxylin and eosin; IOD, integrated
Preference for high-fat diet is developed by young Swiss CD1 mice after short-term feeding and is prevented by NMDA receptor antagonists
Keywords: NMDA، N-methyl-d-aspartate; Feeding behavior; High-fat diet; Dietary preference; ObesityHFD, high-fat diet; RD, regular diet; NMDA, N-methyl-D-Aspartate; PBS, phosphate buffer saline
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of the total flavonoids extracted from Xiaobuxin-Tang
Keywords: NMDA، N-methyl-d-aspartate; ANOVA, analysis of variance; eNOS, endothelial NOS; FST, forced swim test; iNOS, inducible NOS; NMDA, N-methyl-d-aspartate; nNOS, neuronal NOS; NO, nitric oxide; NOS, nitric oxide synthase; SSRIs, selective serotonin reuptake inhibitors; TCM, traditional
Neuroligins, synapse balance and neuropsychiatric disorders
Keywords: NMDA، N-methyl-d-aspartate; ASDs, autism spectrum disorders; GABA, γ-aminobutyric acid; LTP, long-term potentiation; mEPSC, miniature excitatory postsynaptic current; mIPSC, miniature inhibitory postsynaptic current; NMDA, N-methyl-d-aspartate; PSD-95, postsynaptic density protein-9
Neurosteroid allopregnanolone attenuates high glucose-induced apoptosis and prevents experimental diabetic neuropathic pain: In vitro and in vivo studies
Keywords: NMDA، N-methyl-d-aspartate; ALLO, allopregnanolone; AGE, advanced glycation end products; CNS, central nervous system; ERK–MAPK, extracellular signal-regulated kinase/mitogen-activated protein kinase; NMDA, N-methyl-d-aspartate; MTT, 3-[4,5-dimethyl-2-thiazolyl]-2,5-diphenyl-2-tetra
Effect of early stress on hippocampal gray matter is influenced by a functional polymorphism in EAAT2 in bipolar disorder
Keywords: NMDA، N-methyl-d-aspartate; BD, Bipolar Disorder; ACE, Adverse Childhood Experiences; GM, Gray Matter; Glx, glutamate/glutamine; NMDA, N-methyl-D-aspartate; EAATs, excitatory amino acid transporters; SLC1A2, solute carrier family 1 (glial high affinity glutamate transporter), member
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons
Keywords: NMDA، N-methyl-d-aspartate; NMDA, N-methyl-d-aspartate; BK channels, large-conductance Ca2+- and voltage-activated K+ channels; Pax, paxilline; Ibtx, iberiotoxin; OGD, oxygen–glucose deprivation; KATP, ATP-sensitive K+ channels; E, embryonic age; HBSS, Hank's Balanced Salt Solution;
Administration of S-methyl-l-thiocitrulline protects against brain injuries after intracerebral hemorrhage
Keywords: NMDA، N-methyl-d-aspartate; BBB, blood–brain barrier; CSF, cerebral spinal fluid; ICH, intracerebral hemorrhage; MCID, microcomputer image device; MMP, matrix metalloproteinase; NADPH-d, nicotinamide adenine dinucleotide phosphate-diaphorase; NMDA, N-methyl-d-aspartate; NMDAR, NMDA
Discovery of tetrahydropyrido[4,3-d]pyrimidine derivatives for the treatment of neuropathic pain
Keywords: NMDA، N-methyl-d-aspartate; GABA, gamma-aminobytyric acid; NMDA, N-methyl-D-aspartate; AMPA, 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid; PDE, phosphodiesterase; P2X7, purinoreceptor subtype; DCM, dichloromethane; THF, tetrahydrofuran; DMF, dimethyl formamide; ELISA,
Rem2 in the bullfrog (Rana catesbeiana): Patterns of expression within the central nervous system and brain expression at different ontogenetic stages
Keywords: NMDA، N-methyl-d-aspartate; bp, base pairs; cDNA, DNA complimentary to RNA; DNase, deoxyribonuclease; NMDA, N-methyl-d-aspartate; ORF, open reading frame; RNase, ribonuclease; UTR, untranslated region(s); ′(prime), denotes a truncated gene at the indicated sideGTPase; Gene; Amphibia
N-methyl-d-aspartate inhibits cerebellar Purkinje cell activity via the excitation of molecular layer interneurons under in vivo conditions in mice
Keywords: NMDA، N-methyl-d-aspartate; ACSF, artificial cerebrospinal fluid; NMDA, N-methyl-d-aspartate; MLI, molecular layer interneuron; PC, Purkinje cell; GABA, γ-aminobutyric acidNMDA; Cerebellar; Molecular layer interneuron; Purkinje cell; Extracellular recording; GABAA receptor
In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist
Keywords: NMDA، N-methyl-d-aspartate; BSA, bovine serum albumin; CNS, central nervous system; COMT, catechol-O-methyl transferase; EIC, extracted ion current; IS, internal standard; NADPH, nicotinamide adenine dinucleotide phosphate; NMDA, N-methyl-d-aspartate; PAPS, adenosine 3′-phosphate 5′
Predictive validity of a MK-801-induced cognitive impairment model in mice: Implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically
Keywords: NMDA، N-methyl-d-aspartate; CIAS, cognitive impairment associated with schizophrenia; IA, inhibitory avoidance; MK-IA, MK-801 inhibitory avoidance; NMDA, N-methyl-d-aspartate; FDA, U.S. Food and Drug Administration; PCP, phencyclidine; IP, intraperitoneal; CNS, central nervous syste
From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes
Keywords: NMDA، N-methyl-d-aspartate; NMDA receptor antagonist; Conus peptides; NMR structure; Molecular modeling; Subtype-selective antagonist; Glutamate receptorsGla, γ, gamma-carboxyglutamate; NMDA, N-methyl-d-aspartate; Fmoc, N-(9-fluorenyl) methoxycarbonyl; MTBE, methyl-tert-butyl ether;
AMP kinase regulates K-ATP currents evoked by NMDA receptor stimulation in rat subthalamic nucleus neurons
Keywords: NMDA، N-methyl-d-aspartate; aCSF, artificial cerebrospinal fluid; AMPK, 5′-adenosine monophosphate-activated protein kinase; CaMKKβ, calmodulin-dependent protein kinase kinase beta; gKCa, calcium-activated potassium conductance; NMDA, N-methyl-d-aspartate; NO, nitric oxide; NOS, nit
The role of 5-HT7 receptor antagonism in the amelioration of MK-801-induced learning and memory deficits by the novel atypical antipsychotic drug lurasidone
Keywords: NMDA، N-methyl-d-aspartate; AS19, (2S)-(+)-5-(1,3,5-trimethylpyrazol-4-yl)-2-(dimethylamino) tetralin; NMDA, N-methyl-d-aspartate; PCP, phencyclidine; 5-HT, serotonin5-HT7; Passive avoidance; Lurasidone; Antipsychotic; Cognition
The neuroprotective effect of acute moderate alcohol consumption on caspase-3 mediated neuroapoptosis in traumatic brain injury: The role of lysosomal cathepsin L and nitric oxide
Keywords: NMDA، N-methyl-d-aspartate; TBI, traumatic brain injury; NMDA, N-methyl-d-aspartate; NO, nitric oxide; SF, supernatant (cytosolic) fraction; FEL, fraction enriched with lysosomes; SF/FEL, supernatant (cytosolic) fraction/the fraction enriched with lysosomes; Ac-DEVD-pNA, acetyl-Asp-
Effect of prenatal stress on density of NMDA receptors in rat brain
Keywords: NMDA، N-methyl-d-aspartate; NMDA, N-methyl-d-aspartate; CBL, corticosterone blood level; COS, corticosterone; PS, prenatal stress; HPA, hypothalamic–pituitary–adrenal; GD, gestation day; EDTA, ethylenediaminetetraacetic acid; RIA, radioimmunoassay; IHC, immunohistochemistry; TBS, tr