
Synthesis, physicochemical and biological studies of technetium-99m labeled tacrine derivative as a diagnostic tool for evaluation of cholinesterase level
Keywords: Tac; tacrine (1,2,3,4-tetrahydroacridin-9-amine); AD; Alzheimer's disease; AChE; acetylcholinesterase; CNS; central nervous system; IC50; half maximal inhibitory concentration; BM; biologically active molecule; BFCA; Bifunctional Coupling Agent; NS3; tr