Keywords: فارماکوکینتیک غیرخطی; protein binding; clinical pharmacokinetics; nonlinear pharmacokinetics;
مقالات ISI فارماکوکینتیک غیرخطی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: فارماکوکینتیک غیرخطی; albumin; mathematical model; pharmacokinetics; protein binding; organic anion-transporting polypeptide transporters; food effects; hepatic transport; nonlinear pharmacokinetics; clinical pharmacokinetics; ADME; BA; bioavailability; BCS; biopharmaceutica
Keywords: فارماکوکینتیک غیرخطی; clinical study; microdose; cassette dose; Nonlinear pharmacokinetics; bioavailability; first-pass metabolism; dose proportionality; oral absorption
TimeâDependent Effects of Hydrophobic AmineâContaining Drugs on Lysosome Structure and Biogenesis in Cultured Human Fibroblasts
Keywords: فارماکوکینتیک غیرخطی; pharmacokinetics; chronopharmacokinetics; cell culture; nonlinear pharmacokinetics; physicochemical properties; lipids;
Issues, challenges, and opportunities in model-based drug development for monoclonal antibodies
Keywords: فارماکوکینتیک غیرخطی; pharmacokinetics/pharmacodynamics; computational biology; physiological model; pharmacokinetics; pharmacodynamics; allometry; nonlinear pharmacokinetics; antibody; PK/PD
Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration
Keywords: فارماکوکینتیک غیرخطی; Visnagin; Ammi visnaga; Michaelis–Menten kinetics; Nonlinear pharmacokinetics; Nonlinear mixed effect modeling; NONMEM
Interspecies Scaling in Pharmacokinetics: A Novel Whole-Body Physiologically Based Modeling Framework to Discover Drug Biodistribution Mechanisms in vivo
Keywords: فارماکوکینتیک غیرخطی; nonlinear pharmacokinetics; whole-body physiologically based pharmacokinetic model; cyclosporin; scaling; biodistribution; animal model; metabolic clearance; drug transport; preclinical pharmacokinetics; individualized drug therapy;
An examination of the potential effect of lipids on the firstâpass metabolism of the lipophilic drug anethol trithione
Keywords: فارماکوکینتیک غیرخطی; anethol trithione; medium chain triglycerides; firstâpass metabolism; hepatic metabolism; nonlinear pharmacokinetics; dose proportionality; drug metabolizing enzymes; inhibition; formulation; lipids;
Modeling and design of transdermal drug delivery patches containing an external heating device
Keywords: فارماکوکینتیک غیرخطی; Transdermal; Nonlinear pharmacokinetics; Mathematical model; Heat; Optimization; Process design
Pharmacokinetics analysis of sustained release hGH biodegradable implantable tablets using a mouse model of human ovarian cancer
Keywords: فارماکوکینتیک غیرخطی; Proteins; Poly (d,l-lactic-co-glycolic acid); Polymeric drug delivery systems; Cancer; High performance liquid chromatography; Nonlinear pharmacokinetics;
Role of metabolites for drugs that undergo nonlinear first-pass effect: Impact on bioequivalency assessment using single-dose simulations
Keywords: فارماکوکینتیک غیرخطی; absorption; bioequivalence; first-pass metabolism; nonlinear pharmacokinetics; simulations;
Pharmacokinetics and immunoglobulin response of subcutaneous and intravenous atacicept in patients with systemic lupus erythematosus
Keywords: فارماکوکینتیک غیرخطی; APRIL; atacicept; BLyS; pharmacokinetics; systemic lupus erythematosus; bioavailability; dose-response/dose proportionality; nonlinear pharmacokinetics;
Simulation Modelling of Human Intestinal Absorption using Caco-2 Permeability and Kinetic Solubility Data for Early Drug Discovery
Keywords: فارماکوکینتیک غیرخطی; mathematical model; Caco-2 cells; gastrointestinal transit; in silico modeling; in vitro/in vivo correlations (IVIVC); intestinal absorption; pharmacokinetics; physiological model; solubility; nonlinear pharmacokinetics;
Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: Possible role in dose-dependent pharmacokinetics
Keywords: فارماکوکینتیک غیرخطی; intestinal absorption; intestinal metabolism; nonlinear pharmacokinetics; P-glycoprotein; mucosal export; cytochrome P4503A;
Hepatobiliary Disposition of Liposomal Amphotericin B in the Isolated Perfused Rat Liver
Keywords: فارماکوکینتیک غیرخطی; liposomes; hepatobiliary disposition; hepatic clearance; biliary excretion; nonlinear pharmacokinetics;
Application of substrate depletion assay for early prediction of nonlinear pharmacokinetics in drug discovery: Assessment of nonlinearity of metoprolol, timolol, and propranolol
Keywords: فارماکوکینتیک غیرخطی; first-pass metabolism; hepatic clearance; in vitro/in vivo correlations; nonlinear pharmacokinetics; physiological model; simulation;
Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: Association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium
Keywords: فارماکوکینتیک غیرخطی; organic cations (OCs); TBuMA; Ussing chamber; intestinal secretion/transport; nonlinear pharmacokinetics; P-glycoprotein (P-gp); efflux pumps; organic cation transporters (OCT);