Research ArticleHCV NS5A and IRF9 compete for CypA binding
Keywords: HCV; NS5A; cyclophilin A; cyclophilin inhibitors; IFN.;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HCV NS5A
Keywords: Hepatitis C; HCV; NS5A; Antiviral;
HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides
Keywords: Hepatitis C virus (HCV); NS5A; Daclatasvir; Antiviral;
Synthesis and evaluation of novel potent HCV NS5A inhibitors
Keywords: NS5A; Antiviral; HCV
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics
Keywords: Antiviral; HCV; Hepatitis C; NS5A; Peptidomimetics; γ-Turn
Research ArticleThe metabolic regulator PGC-1α links hepatitis C virus infection to hepatic insulin resistance
Keywords: HCV; hepatitis C virus; PGC-1α; peroxisome proliferator-activated receptor gamma, co-activator 1α; G6Pase; glucose-6 phosphatase; RNA; ribonucleic acid; PI3; phosphatidylinositol 3-kinase; FLRP; full length replicon; SGR; subgenomic replicon; NS5A; non-
Research ArticleHepatitis C virus non-structural 5B protein interacts with cyclin A2 and regulates viral propagation
Keywords: HCV; hepatitis C virus; NS5A; non-structural 5A; NS5B; non-structural 5B; HCC; hepatocellular carcinoma; CycA2; cyclin A2; CDK1&2; cyclin-dependent kinase 1&2; GST; glutathione S-transferase; PBS; phosphate-buffered saline; TRITC; tetramethylrhodamine iso
Classical swine fever virus NS5A protein interacts with 3′-untranslated region and regulates viral RNA synthesis
Keywords: Classical swine fever virus; NS5A; NS5B; 3′UTR
Classical swine fever virus NS5A regulates viral RNA replication through binding to NS5B and 3′UTR
Keywords: Classical swine fever virus; NS5A; NS5B; Viral replication; NS5A–NS5B interaction
Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein
Keywords: Hepatitis C virus; NS5A; Inhibitor; Direct-acting antiviral; Mechanism of action; Combination therapy;
Second generation direct antivirals and the way to interferon-free regimens in chronic HCV
Keywords: Hepatitis C virus; Direct acting antiviral agents; NS3/4A protease inhibitor; NS5A; NS5B; Nucleotide inhibitors; Non-nucleotide inhibitors; Cyclophilin inhibitor
Colony-forming assays reveal enhanced suppression of hepatitis C virus replication using combinations of direct-acting antivirals
Keywords: HCV; NS5A; Filibuvir; Colony-forming assay; Direct-acting antiviral; Combination;
HCV RNA decline in the first 24 h exhibits high negative predictive value of sustained virologic response in HIV/HCV genotype 1 co-infected patients treated with peginterferon and ribavirin
Keywords: 24 h; Viral kinetics; SVR; HIV/HCV co-infection; HCV treatment; NS5A
Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase
Keywords: Rluc, Renilla reniformis luciferase; RLU, relative light units; IFA, immunofluorescence assayHepatitis C; HCV; IRES; Benzimidazole; Renilla luciferase; NS5A
The NS5A Replication Complex Inhibitors: Difference Makers?
Keywords: Hepatitis C; NS5A; Replication; Inhibitor;
Hepatitis C virus nonstructural protein-5A activates sterol regulatory element-binding protein-1c through transcription factor Sp1
Keywords: Hepatitis C virus; NS5A; SREBP-1c; Sp1
Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway
Keywords: Akt; Curcumin; HCV; NS5A; SREBP-1
Classical swine fever virus NS3 is an IRES-binding protein and increases IRES-dependent translation
Keywords: Classical swine fever virus; IRES; NS3; NS5A; NS5B
HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors
Keywords: HCV; Cyclophilin A; NS5A;
Development of a high-content screening assay to identify compounds interfering with the formation of the hepatitis C virus replication complex
Keywords: Hepatitis C virus; Replication complex; NS5A; Enhanced green fluorescent protein; Inducible cell line; High-content screening
The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A
Keywords: Hepatitis C virus; NS5A; Cyclophilin A; Cyclosporine A; Interaction; AlphaLISA
Liver cancer: From molecular pathogenesis to new therapies
Keywords: DEB; drug-eluting bead; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; hTERT; human telomerase reverse transcriptase; PDGF; platelet derived growth factor; FAK; focal adhesion kinase; Pyk2; proline-rich tyrosine kinase 2; M
Variants in IL28B in Liver Recipients and Donors Correlate With Response to Peg-Interferon and Ribavirin Therapy for Recurrent Hepatitis C
Keywords: ISDR; IRRDR; Genetic Analysis; Genetic Variations; DW; double-wild; ETR; end of treatment response; HCV; hepatitis C virus; IRRDR; interferon/ribavirin resistance-determining region; ISDR; interferon sensitivity-determining region; ISG; interferon-stimula
Biological activities and molecular interactions of the C-terminal residue of thrombospondin-4, an epitome of acidic amphipathic peptides
Keywords: Cell penetrating peptide; DNA replication; Hepatitis C virus; Integrins; NS5A; Papillomavirus; Posttranscriptional regulation; RNA recognition motifs; ROD1; STAT3; Transcriptional activator E2
Domain 3 of non-structural protein 5A from hepatitis C virus is natively unfolded
Keywords: Hepatitis C virus; NS5A; Domain 3; NMR; Unstructured; Circular dichroism;
Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma
Keywords: Hepatitis C virus; NS5A; Lipid accumulation; PGC-1; PPARγ
Nonstructural 5A protein activates β-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis
Keywords: HCV; hepatitis C virus; NS5A; nonstructural 5A; HCC; hepatocellular carcinoma; GST; glutathione S-transferase; HA; hemaglutinin; IFN; interferon; PBS; phosphate-buffered saline; GFP; green fluorescence protein; TRITC; tetramethylrhodamine isothiocyanate;
Formation and function of hepatitis C virus replication complexes require residues in the carboxy-terminal domain of NS4B protein
Keywords: HCV; NS4B; NS3; NS5A; Subcellular localization; Membrane-association; Replication complex; Membranous web
The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism
Keywords: Hepatitis C virus; NS5A; Genotype; IFN antagonism;
Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes
Keywords: HCV; Hepatitis C virus; NS5A; Non structural 5A; CK2; Casein kinase 2; Phosphorylation
Replication efficiency of chimeric replicon containing NS5A-5B genes derived from HCV-infected patient sera
Keywords: HCV; NS5A; NS5B; Sub-genomic replicon; Quasispecies pools; Transient assay;
The NS5A protein of hepatitis C virus represses gene expression of hRPB10α, a common subunit of host RNA polymerases, through interferon regulatory factor-1 binding site
Keywords: HCV; NS5A; hRPB10α; Host RNA polymerase; IRF-E; IRF-1; Interferon-α
Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication
Keywords: HCV; NS5A; Raf-1; Replication
Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells
Keywords: HCV, hepatitis C virus; NS, non-structural protein; FKBP38, 38kDa FK506-binding protein; HCC, hepatocellular carcinoma; GFP, green fluorescent protein; HA, influenza hemagglutinin; aa, amino acidHepatitis C virus; NS5A; FKBP38; Protein–protein interaction
Overexpression of Hepatitis C Virus NS5A Protein Induces Chromosome Instability via Mitotic Cell Cycle Dysregulation
Keywords: hepatitis C virus; NS5A; mitotic cell cycle; chromosome instability; hepatocellular carcinomaHCV, hepatitis C virus; NS, non-structural; HCC, hepatocellular carcinoma; APC/C, anaphase promoting complex/cyclosome; LOH, loss of heterozygosity; NEBD, nuclear
Hepatitis C virus-related resistance mechanisms to interferon α-based antiviral therapy
Keywords: E2; Hepatitis C; Interferon-α; ISDR; Mutations; NS3A; NS4A; NS5A; Resistance mechanisms;
Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C
Keywords: NS5A; NS5B; ISDR; HCV; HCV dynamics; HCV; hepatitis C virus; IFN; interferon; RdRp; RNA dependent RNA polymerase; PCR; polymerase chain reaction; SVR; sustained viral responder; NR; non-responder; ISDR; interferon sensitivity determining region;
Reduction of hepatitis C virus NS5A phosphorylation through its interaction with amphiphysin II
Keywords: Proteome; NS5A; HCV; Amphiphysin II; Phosphorylation;
Characterization of a HCV NS5A protein derived from a patient with hepatoma
Keywords: Hepatitis C virus; NS5A; Hepatocellular carcinoma; Phosphorylation; Nuclear localization signal; Mutant; Transactivation; Oncogenic promoter; Grb2; Interaction;