Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; AA, arachidonic acid; COX, cyclooxygenase; EPA, eicosapentaenoic acid; NSAIDs, nonsteroidal anti-inflammatory drugs; PGs, prostaglandins; PGI, prostacyclin; TXA, thromboxaneAnti-inflammatory; COX; In vivo; In silico; Pyrazole; Thiazole
مقالات ISI NSAIDs، داروهای ضد التهابی غیر استروئیدی (ترجمه نشده)
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Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; GOO, gastric outlet obstruction; PUD, peptic ulcer disease; H. pylori, Helicobacter pylori; EBD, endoscopic balloon dilatation; NSAIDs, nonsteroidal anti-inflammatory drugs; PPI, proton-pump inhibitor; AST, antisecretory therapy; TTS, through the scopeDuo
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; BSA, bovine serum albumin; CII, type II collagen; CFA, complete Freund’s adjuvant; COX-2, cyclooxygenase-2; iNOS, inducible nitric oxide synthase; NSAIDs, nonsteroidal anti-inflammatory drugs; PBS, phosphate buffer saline; PFA, paraformaldehyde; PMA, phor
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Bariatric surgery; Cholecystectomy; Cholesterol; Gallbladder motility; Metabolic syndrome; Rapid weight lossAP, acute pancreatitis; BMI, body mass index; NSAIDs, nonsteroidal anti-inflammatory drugs; SIRS, systemic inflammatory response syndrome; TNF, tum
A novel model for NSAID induced gastroenteropathy in rats
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; DCF, Diclofenac sodium; EB, Evans Blue; Hb, Haemoglobin; HCT, Haematocrit; LPO, Lipid peroxidation; MDA, Malondialdehyde; NSAIDs, Nonsteroidal anti-inflammatory drugs; PPIs, Proton pump inhibitors; PTZ, Pantoprazole sodium; ROS, Reactive oxygen species.Di
NOSH-sulindac (AVT-18A) is a novel nitric oxide- and hydrogen sulfide-releasing hybrid that is gastrointestinal safe and has potent anti-inflammatory, analgesic, antipyretic, anti-platelet, and anti-cancer properties
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NO, nitric oxide; H2S, hydrogen sulfide; NOSH, nitric oxide-hydrogen sulfide; NSAIDs, nonsteroidal anti-inflammatory drugs; SUL, sulindac; LPS, Lipopolysaccharide; PGE2, Prostaglandin E2; MDA, malondialdehyde; SOD, Superoxide dismutaseNitric oxide; Hydrog
Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Asthma; COX; NSAIDs; eicosanoids; prostaglandin; thromboxane; leukotrienes; airway hyperresponsiveness; mass spectrometry; urinary metabolitesFeno, Fractional exhaled nitric oxide; NSAIDs, Nonsteroidal anti-inflammatory drugs; PGD2, Prostaglandin D2; PGE,
Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; AD, Alzheimer’s disease; APP, amyloid precursor protein; Aβ, amyloid β; cDKO, conditional double-knockout; COX, cyclooxygenase; GFAP, glial fibrillary acidic protein; NFT, neurofibrillary tangle; NSAIDs, nonsteroidal anti-inflammatory drugs; PS, presenili
Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; CNS, central nervous system; CCl4, carbon tetrachloride; DPPH, 2,2-diphenyl-1-picrylhydrazyl; NIDDM, non-insulin dependent diabetes mellitus; NO, nitric oxide; NSAIDs, nonsteroidal anti-inflammatory drugs; ROS, radicals, reactive oxygen species; SGLT, sod
Cox-2 gene variants in migraine
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; MA, migraine with aura; MO, migraine without aura; ICHDII, International Criteria for Headache Disorders; COX, cyclooxygenase; PGE2, prostaglandin E2; NSAIDs, nonsteroidal anti-inflammatory drugs; IHS, International Headache Society; PCR, polymerase chain
Effects of Phonophoresis of Piroxicam and Ultrasound on Symptomatic Knee Osteoarthritis
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Knee; Osteoarthritis; Pain; Phonophoresis; Rehabilitation; Ultrasonic therapyANCOVA, analysis of covariance; CI, confidence interval; NSAIDs, nonsteroidal anti-inflammatory drugs; OA, osteoarthritis; PhP, phonophoresis of piroxicam; US, ultrasound; UT, ul
Celecoxib antagonizes the cytotoxic effect of cisplatin in human gastric cancer cells by decreasing intracellular cisplatin accumulation
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX, cyclooxygenase; CTR1, copper transporter 1; NSAIDs, nonsteroidal anti-inflammatory drugs; PGE2, Prostaglandin E2; PARP, poly (ADP-ribose) polymerase; siRNA, small interference RNA; SC-236, 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]ben
The role of nonsteroidal anti-inflammatory drugs in pediatric patients
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDS, nonsteroidal anti-inflammatory drugs; PDA, patent ductus arteriosus; JIA, Juvenile Idiopathic Arthritis; COX, cyclooxygenase; GI, gastrointestinal; IV, intravenous; IVH, intraventricular hemorrhage; COX-1 and 2, cyclooxygenase-1 and 2; IM, intramu
Ibuprofen ameliorates protein aggregation and astrocytic gliosis, but not cognitive dysfunction, in a transgenic mouse expressing dementia with Lewy bodies-linked P123H β-synuclein
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; PD, Parkinson's disease; AD, Alzheimer's disease; DLB, dementia with Lewy bodies; tg, transgenic; β-syn, β-synuclein; α-syn, α-synuclein; NSAIDs, nonsteroidal anti-inflammatory drugs; GFAP, glial fibrillary acidic protein; qPCR, quantitative polymerase ch
Toxic epidermal necrolysis: Five years of treatment experience from a burn unit
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; AUC, area under the curve; BSA, body surface area; IVIg, intravenous immunoglobulin; NSAIDs, nonsteroidal anti-inflammatory drugs; OR, odds ratio; ROC, receiver operating curve; TEN, toxic epidermal necrolysis
Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; ATR-FTIR, Attenuated Total Reflectance Fourier Transform Infra-Red; CGRP, Calcitonin Gene-Related Peptide; COX-2, Cyclooxygenase-2; EE, Evodia rutaecarpa Extract; EVO, Evodiamine; NSAIDs, Nonsteroidal Anti-Inflammatory Drugs; PEG-400, Polyethylene Glycol
Serial Ultrasonographic Findings of Plantar Fasciitis After Treatment With Botulinum Toxin A: A Case Study
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Botulinum toxin type A; Fasciitis; Plantar; Pain; Rehabilitation; UltrasonographyBTX-A, botulinum toxin A; MRI, magnetic resonance imaging; NSAIDs, nonsteroidal anti-inflammatory drugs; PPT, pressure pain threshold; VAS, visual analog scale
The structure of NS-398 bound to cyclooxygenase-2
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX, cyclooxygenase; hu, human; mu, murine; ov, ovine; AA, arachidonic acid; NS-398, N-(2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide; MR, molecular replacement; NSAIDs, nonsteroidal anti-inflammatory drugs; βOG, n-octyl β-d-glucopyranosideCyclooxygen
Medication, Surgery, and Physiotherapy Among Patients With the Hypermobility Type of Ehlers-Danlos Syndrome
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Ehlers-Danlos syndrome; Drug therapy; General surgery; Physiotherapy; RehabilitationEDS, Ehlers-Danlos syndrome; EDS-HT, hypermobility type of EDS; NSAIDs, nonsteroidal anti-inflammatory drugs; SIP, Sickness Impact Profile; TENS, transcutaneous electrical
ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid β-induced cell cytotoxicity
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; H2S, hydrogen sulfide; Aβ, amyloid beta; CBS, cystathionine β-synthase; CSE, cystathionine γ-lyase; AD, Alzheimer disease; CSF, cerebrospinal fluid; NSAIDs, nonsteroidal anti-inflammatory drugs; DMEM, Dulbecco's modified Eagle's medium; COX-2, cyclooxygen
Impact of nasogastric lavage on outcomes in acute GI bleeding
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NGL, nasogastric lavage; NSAIDs, nonsteroidal anti-inflammatory drugs; NVUGIH, nonvariceal upper GI hemorrhage; OR, odds ratio
Emergency Reversal of Antiplatelet Agents in Patients Presenting with an Intracranial Hemorrhage: A Clinical Review
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Antiplatelet agent; Aspirin; Clopidogrel; Coagulopathy; Intracranial hemorrhage; Platelet transfusion; Stroke; TraumaASA, Aspirin (acetylsalicylic acid); COX-1, Cyclooxygenase-1; ICH, Intracranial hemorrhage; NSAIDs, Nonsteroidal anti-inflammatory drugs;
Association of smoking and flat adenomas: results from an asymptomatic population screened with a high-definition colonoscope
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX2, cyclooxygenase-2; CRC, colorectal cancer; IQR, interquartile range; JRSC, Japanese Research Society Classification; MMR, mismatch repair; NSAIDs, nonsteroidal anti-inflammatory drugs; OR, odds ratio
Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX-2, cyclooxygenase-2; cPGES, cytosolic PGES; mPGES-1, microsomal prostaglandin E synthase-1; PGE2, prostaglandin E2; NSAIDs, nonsteroidal anti-inflammatory drugs; COXibs, COX-2 inhibitors; RA, rheumatoid arthritis; OA, osteoarthritis; TXB2, thromboxane
The effect of opioid antagonists on synergism between dexketoprofen and tramadol
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; DEX, dexketoprofen; NA, noradrenalin; DOR, δ-opioid receptor; KOR, κ-opioid receptor; MPE, maximum posible effect; TRAM, tramadol; MOR, μ-opiod receptor; GABA, gamma-amino-butyric acid; PA
Allodynia corresponding to the levels of cervical cord injury treated by surgical decompression: a report of 3 cases
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; CTM, Computerized tomographic myelogram; IASP, International Association for the Study of Pain; MRI, magnetic resonance imaging; NSAIDs, nonsteroidal anti-inflammatory drugs; SCI, spinal cord injury; VAS, visual analogue scaleSpinal cord injury; Cervical
EUS-guided FNA of solid pancreatic masses: a prospective, randomized trial comparing 22-gauge and 25-gauge needles
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; ASA, aspirin; NSAIDs, nonsteroidal anti-inflammatory drugs
Intravenous proton pump inhibition utilization and prescribing patterns escalation: a comparison between early and current trends in use
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; HRES, high-risk endoscopic stigmata; ICU, intensive care unit; IV, intravenous; NPO, nothing by mouth; NSAIDs, nonsteroidal anti-inflammatory drugs; NVUGIB, nonvariceal upper GI bleeding; PPI, proton pump inhibitors; PUD, peptic ulcer disease; UGI, upper
Is there a role for second-look capsule endoscopy in patients with obscure GI bleeding after a nondiagnostic first test?
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; CE, capsule endoscopy; DBE, double-balloon enteroscopy; NSAIDs, nonsteroidal anti-inflammatory drugs; OGIB, obscure GI bleeding
Sociodemographic Factors Influence Use of Proton Pump Inhibitors Among Users of Nonsteroidal Anti-Inflammatory Drugs
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; CI, confidence interval; COX, cyclo-oxygenase; GI, gastrointestinal; GP, general practitioner; H2RAs, histamine-2 receptor antagonists; NSAIDs, nonsteroidal anti-inflammatory drugs; OR, odds ratio; PPI, proton pump inhibitor; PUB, perforation, peptic ulce
The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: A physico-chemical study with lecithin phospholipids
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, Nonsteroidal anti-inflammatory drugs; DMPC, dimyristoylphosphatidylcholine; FTIR, Fourier-transform infrared spectroscopy; ATR, attenuated total reflection; ITC, isothermal titration calorimetry; FRET, Förster resonance energy transfer spectroscop
Suppression of aromatase in human breast cells by a cyclooxygenase-2 inhibitor and its analog involves multiple mechanisms independent of cyclooxygenase-2 inhibition
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; PGE2, Prostaglandin E2; COX-2, cyclooxygenase-2; NSAIDs, nonsteroidal anti-inflammatory drugs; ER, estrogen receptors; AIs, aromatase inhibitors; SERMs, selective estrogen modulators; TPA, tetradecanoyl phorbol acetate; DEX, dexamethasone; FSK, forskolin;
Fifty years of Biochemical Pharmacology: The discipline and the journal
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; ACE, angiotensin-converting enzyme; RAS, renin–angiotensin system; SARs, structure–activity relationships; NSAIDs, nonsteroidal anti-inflammatory drugs; NCEs, novel chemical entities; RA, rheumatoid arthritis; VRSA, vancomycin-resistant S. aureus; MRSA, m
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; HWB, human whole blood; tNSAIDs, traditional nonsteroidal anti-inflammatory drugs; GI, gastrointestinal; CV, cardiovascular; DMEM, Dulbecco’s modified Eagle’s medium; FBS, fetal bovine ser
Effect of Risk Factors on Complicated and Uncomplicated Ulcers in the TARGET Lumiracoxib Outcomes Study
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; BMI, body mass index; CI, confidence interval; COX, cyclooxygenase; CV, cardiovascular; GI, gastrointestinal; HR, hazard ratio; NNT, number of patients needed to be treated; NSAIDs, nonsteroidal anti-inflammatory drugs; OA, osteoarthritis; TARGET, Therape
Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs; EGR-1, early growth response gene 1; MAP kinase, mitogen activated protein kinase; ERK, extracellular signal-regulated protein kinase; BFGF, basic fibroblast growth factor; PDGF, platelet-derived growth factor
Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX, cyclooxygenase; MPO, myeloperoxidase; NO, nitric oxide; NOS, NO synthase; NSAIDs, nonsteroidal anti-inflammatory drugs; PCR, polymerase chain reaction; SNOs, S-nitrosothiolsUlcer; NSAIDs; Nitric oxide; Nitrite; Nitrate; Saliva
Novel role of famotidine in downregulation of matrix metalloproteinase-9 during protection of ethanol-induced acute gastric ulcer
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs; ROS, reactive oxygen species; MMP, matrix metalloproteinases; ECM, extracellular matrix; MPO, myeloperoxidase; DMSO, dimethyl sulfoxide; TNFα, tumor necrosis factor α; NAC, N-acetylcysteine; RT-PCR, reverse tr
Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs; COX-2, cyclooxygenase-2; FBS, fetal bovine serum; TCF, T-cell factorCelecoxib; Survivin; Promoter activity; Apoptosis; Colon cancer cell; Nonsteroidal anti-inflammatory drugs (NSAIDs)
Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX, cyclooxygenase; PGH2, prostaglandin endoperoxide H2; NSAIDs, nonsteroidal anti-inflammatory drugs; LPS, lipopolysaccharide; CRE, cAMP response element; SRE, sterol response element; NF-κB, nuclear factor-kappa B; AP-1, Activator Protein-1; IL-1, inte
Adalimumab therapy for childhood uveitis
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; ANA, Antinuclear antibody; JLA, juvenile idiopathic arthritis; NSAIDs, Nonsteroidal anti-inflammatory drugs; TNF, Tumor necrosis factor
Effect of Nonsteroidal Anti-Inflammatory Drug Use on the Incidence of Erectile Dysfunction
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; analgesics; arthritis; impotenceED, erectile dysfunction; IDR, incidence density ratio; IIEF, International Index of Erectile Function; NSAIDs, nonsteroidal anti-inflammatory drugs
Recombinant activated factor VII in an unselected series of cases with upper gastrointestinal bleeding
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; aPTT, activated partial thromboplastin time; FFP, fresh frozen plasma; INR, international normalized ratio; NSAIDs, nonsteroidal anti-inflammatory drugs; PRBC, packed red blood cells; PT, prothrombin time; rFVIIa, recombinant activated factor VII; TIPS, t
Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; G-Gly, Glycine-extended gastrin; NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclo-oxygenase; PGE-2, prostaglandin E2; ERK, p42/44 extracellular signal regulated kinase; p38 MAP kinase, p38 mitogen activated protein kinase; NF-κB, nuclear factor ka
Marked Interindividual Variability in the Response to Selective Inhibitors of Cyclooxygenase-2
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; COX, cyclooxygenase; NSAIDs, nonsteroidal anti-inflammatory drugs; PGs, prostaglandins; PGI2, prostacyclin; PGI-M, 2,3-dinor-6 keto prostaglandin F1α; TxB2, thromboxane; Tx-M, 11-dehydrothromboxane B2
Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2+/− mice
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; Chaps, 3-[(3-cholamidopropyl)dimethylammonio]propanesulfonate; DHE, dihydroethidium; NSAIDs, nonsteroidal anti-inflammatory drugs; mPT, mitochondrial permeability transition; PCR, polymerase chain reaction; ROS, reactive oxygen species; SDS-PAGE, sodium d
Long-term Outcome of Helicobacter pylori–Negative Idiopathic Bleeding Ulcers: A Prospective Cohort Study
Keywords: NSAIDs، داروهای ضد التهابی غیر استروئیدی; NSAIDs, nonsteroidal anti-inflammatory drugs