Keywords: Heart; Advanced glycation endproducts; Insulin resistance; Cardiomyocyte; Diabetes; O-GlcNAcylation; Glycation; Glycosylation
مقالات ISI (ترجمه نشده)
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Keywords: Glycosaminoglycan; UDP-GlcUA; UDP-GlcNAc; AMPK; O-GlcNAcylation; HBP;
Keywords: Glycosaminoglycan; Extracellular matrix; AMPK; O-GlcNacylation; Hyaluronan receptor;
Keywords: Chronobiology; Heart; Metabolism; O-GlcNAcylation;
O-GlcNAcylation affects β-catenin and E-cadherin expression, cell motility and tumorigenicity of colorectal cancer
Keywords: CTD; carboxyl terminal domain; GlcNAc; N-acetylglucosamine; OGA; O-GlcNAcase; OGT; O-GlcNAc transferase; Ser; serine; WGA; wheat germ agglutinin; Thr; threonine; TMG; Thiamet G; O-GlcNAcylation; β-catenin; E-cadherin; Cell-motility; EMT; Cancer metastasi
BLT1-mediated O-GlcNAcylation is required for NOX2-dependent migration, exocytotic degranulation and IL-8 release of human mast cell induced by Trichomonas vaginalis-secreted LTB4
Keywords: Trichomonas vaginalis; Human mast cells; BLT1; O-GlcNAcylation; NOX2; Leukotriene B4;
Neuronal O-GlcNAc transferase regulates appetite, body weight, and peripheral insulin resistance
Keywords: Appetite; Body weight gain; Insulin resistance; Neuronal OGT; O-GlcNAcylation;
Functional significance of O-GlcNAc modification in regulating neuronal properties
Keywords: PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF
Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation
Keywords: hyperinsulinemia; infarct size; microRNA; O-GlcNAcylation; ATG4A; autophagy-related gene 4a; BIM; Bcl-2-like protein 11; CVD; cardiovascular disease; DM; diabetes mellitus; I/R; ischemia/reperfusion; MI; myocardial infarction; OGT; O-GlcNac transferase;
O-GlcNAcylation site mapping by (azide-alkyne) click chemistry and mass spectrometry following intensive fractionation of skeletal muscle cells proteins
Keywords: O-GlcNAcylation; Click chemistry; Mass spectrometry; Post-translational modifications; Sites localization; Skeletal muscle cells; Fractionation;
Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease
Keywords: Prostaglandin J2; APP; Secretases; O-GlcNAcylation; Apoptosis;
AKT-independent activation of p38 MAP kinase promotes vascular calcification
Keywords: ALP; alkaline phosphatase; α-SMA; smooth muscle specific α-actin; ApoE; apolipoprotein E; ColIa1; type I collagen A1; DCA; sodium dichloroacetate; ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; OC; osteocalcin; O-GlcNAcylation; O-
Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3β inactivation in a human gastric carcinoma cell line, MKN45 cells
Keywords: O-GlcNAcylation; Ubiquitination; FOXM1; GSK-3β;
O-GlcNAcylation modulates PKA-CREB signaling in a manner specific to PKA catalytic subunit isoforms
Keywords: Protein kinase A; CREB; O-GlcNAcylation; Phosphorylation;
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease
Keywords: Alzheimer disease; O-GlcNAcylation; Phosphorylation; Glucose metabolism; Insulin signaling;
O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis
Keywords: RACK1; O-GlcNAcylation; Translation; Ribosome; Hepatocellular carcinoma; PKCβII;
O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease
Keywords: 3xTg-AD; triple transgenic mouse model of Alzheimer's disease; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; Asn; asparagine residue; ATP5A; ATP synthase subunit α; Aβ; amyloid-β peptide; AβPP; amyloid-β precursor protein; ER; endo
Western blot data using two distinct anti-O-GlcNAc monoclonal antibodies showing unique glycosylation status on cellular proteins under 2-deoxy-d-glucose treatment
Keywords: 2-deoxy-d-glucose; O-GlcNAcylation; Sp1; Teratocarcinoma;
O-GlcNAcylation of amyloid-β precursor protein at threonine 576 residue regulates trafficking and processing
Keywords: Amyloid-β protein precursor; Alzheimer's disease; O-GlcNAcylation; Amyloid;
Suppressive role of OGT-mediated O-GlcNAcylation of BAP1 in retinoic acid signaling
Keywords: BAP1; OGT; O-GlcNAcylation; Retinoic acid; Differentiation; Embryonic stem cells;
Measuring O-GlcNAc cleavage by OGA and cell lysates on a peptide microarray
Keywords: O-GlcNAcylation; O-GlcNAcase; O-GlcNAcylated peptide; Peptide microarray; Cell lysate;
Yeast cells as an assay system for in vivo O-GlcNAc modification
Keywords: S. cerevisiae; Saccharomyces cerevisiae; GlcNAc; N-acetylglucosamine; TPR; tetratricopeptide repeat; OGT; O-GlcNAc transferase; sOGT; short OGT; ncOGT; nuclear and cytoplasmic OGT; mOGT; mitochondrial OGT; OGA; O-GlcNAcase; HAT; histone acetyltransferase;
Effect of amyloid-Î (25-35) in hyperglycemic and hyperinsulinemic rats, effects on phosphorylation and O-GlcNAcylation of tau protein
Keywords: Amyloid-Beta; O-GlcNAcylation; Tau protein; GSK3beta; Hyperglycemia; Hyperinsulinemia;
A novel mechanism of pre-transplant insulin resistance contributing to post-transplant complications: Cyclosporin A-induced O-GlcNAcylation
Keywords: Cyclosporin A; O-GlcNAcylation; Apoptosis; Reactive oxygen species; Transplantation; Insulin resistance;
The UPR reduces glucose metabolism via IRE1 signaling
Keywords: Unfolded protein response; Glucose homeostasis; Mitochondrial respiration; Glycolysis; IRE1; O-GlcNAcylation;
Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase
Keywords: Oxidative stress; O-GlcNAcylation; OGT; Transcription factor; Protein stability;
A novel strategy for global mapping of O-GlcNAc proteins and peptides using selective enzymatic deglycosylation, HILIC enrichment and mass spectrometry identification
Keywords: O-GlcNAcylation; Selective enzymatic deglycosylation; HILIC enrichment; Urinary protein; Proteomics;
O-GlcNAcylation is a key modulator of skeletal muscle sarcomeric morphometry associated to modulation of protein-protein interactions
Keywords: Sarcomere structure; Skeletal muscle cells; O-GlcNAcylation; Protein-protein interactions; Desmin; αB-crystallin;
O-GlcNAc regulates NEDD4-1 stability via caspase-mediated pathway
Keywords: O-GlcNAcylation; NEDD4-1; OGT; Caspase;
Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation
Keywords: Glucokinase; O-GlcNAcylation; Liver; Mouse; siOGT; Glucose metabolism;
Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells
Keywords: F6P; fructose 6-phosphate; HBP; Hexosamine Biosynthetic Pathway; GlcN6P; glucosamine-6-phosphate; GFAT; glutamine-fructose-6-phosphate amidotransferase; UDP-GlcNAc; UDP-N-acetylglucosamine; O-GlcNAc; O-GlcNAcylation; GAM; Glucosamine; VEGF; vascular endot
Review ArticleO-GlcNAcylation: A regulator of tau pathology and neurodegeneration
Keywords: Alzheimer's disease; O-GlcNAcylation; Tau; Hyperphosphorylation; Neurodegeneration;
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer’s disease
Keywords: O-GlcNAcylation; 3xTg-AD mice; tau protein; hippocampus
ELISA-PLA: A novel hybrid platform for the rapid, highly sensitive and specific quantification of proteins and post-translational modifications
Keywords: ELISA; Proximity ligation assay; O-GlcNAcylation; Phosphorylation;
O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α
Keywords: O-GlcNAcylation; OGA; OGT; Placenta; Vasculogenesis; HIF-1α; Hypoxia
2-Deoxyglucose induces the expression of thioredoxin interacting protein (TXNIP) by increasing O-GlcNAcylation - Implications for targeting the Warburg effect in cancer cells
Keywords: TXNIP; 2-Deoxyglucose; ChoRE; O-GlcNAcylation; MondoA;
O-linked N-acetylglucosamine (O-GlcNAc) protein modification is increased in the cartilage of patients with knee osteoarthritis
Keywords: Cartilage; Chondrocytes; Glycosylation; O-GlcNAcylation; Hypertrophic differentiation;
The mitochondrial O-linked N-acetylglucosamine transferase (mOGT) in the diabetic patient could be the initial trigger to develop Alzheimer disease
Keywords: O-GlcNAcylation; O-glycosyl transferase; Diabetes mellitus; Alzheimer disease; Mitochondria
Regulation of keratinocyte differentiation by O-GlcNAcylation
Keywords: Keratinocyte differentiation; O-GlcNAcylation; Sp-1
X marks the spot: Does it matter that O-GlcNAc Transferase is an X-linked gene?
Keywords: O-GlcNAc Transferase; O-GlcNAcylation; X-linked gene; X-inactivation; Embryogenesis;
Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells
Keywords: ADAM; a disintegrin and metalloprotease; BAPTA-AM; O,Oâ²-Bis [2-aminophenyl] ethyleneglycol-N,N,Nâ²,Nâ²-tetraacetic acid tetraacetoxymethyl ester; DON; deoxynorleucine; ICT-EIA; immune complex transfer enzyme immunoassay; IR; insulin receptor; OGA; β-
Chitosan oligosaccharides block LPS-induced O-GlcNAcylation of NF-κB and endothelial inflammatory response
Keywords: Chitosan oligosaccharides; Lipopolysaccharides (LPS); Endothelial cells; O-GlcNAcylation; Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB); Inflammatory response;
β-Catenin is O-GlcNAc glycosylated at Serine 23: Implications for β-catenin's subcellular localization and transactivator function
Keywords: β-Catenin; O-GlcNAcylation; Subcellular localization; Transcriptional function
FBXW10 is negatively regulated in transcription and expression level by protein O-GlcNAcylation
Keywords: Cross-talk; Ubiquitination; O-GlcNAcylation; F-box protein; FBXW10; FBXO4;
O-GlcNAcylation of BMAL1 regulates circadian rhythms in NIH3T3 fibroblasts
Keywords: BMAL1; O-GlcNAcylation; Stability; Transcriptional activity; Circadian rhythms;
O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment
Keywords: Alzheimer's disease (AD); β-Amyloid (Aβ); O-GlcNAcylation; 5XFAD transgenic mouse; Nicastrin; NButGT;
Post-translational protein modification by O-linked N-acetyl-glucosamine: Its role in mediating the adverse effects of diabetes on the heart
Keywords: O-GlcNAc; O-GlcNAcylation; Diabetes; Cardiomyocytes
A dynamic view to the modulation of phosphorylation and O-GlcNAcylation by inhibition of O-GlcNAcase
Keywords: GlcNAc, β-N-acetylglucosamine; OGA, O-GlcNAcase or β-N-acetylglucosaminidase; OGT, O-linked N-acetylglucosaminetransferase; NFTs, neurofibrillary tangles; PHFs, paired helical filamentsModeling; Reciprocal regulation; O-GlcNAcylation; Phosphorylation
β-Glucan administration to diabetic rats alleviates oxidative stress by lowering hyperglycaemia, decreasing non-enzymatic glycation and protein O-GlcNAcylation
Keywords: AGE; advanced glycation end product; BGEE; β-glucan-enriched extract; BSA; bovine serum albumin; CAT; catalase; D; diabetic animal group; ND; non-diabetic animal group; HBP; hexosamine biosynthetic pathway; i.p.; intraperitoneal; O-GlcNAc; O-linked N-ace
O-GlcNAc modification of the coat protein of the potyvirus Plum pox virus enhances viral infection
Keywords: O-GlcNAcylation; Plum pox virus; Potyvirus; Capsid protein; Mass spectrometry