Keywords: OFT، آزمون میدان باز; Depression; Anxiety; Neuropeptides; Somatostatin; sst4 receptor; Fos immunohistochemistryEPM, elevated plus maze test; OFT, open field test; FST, forced swim test; TST, tail suspension test; i.p., intraperitoneal; dRN, the dorsal raphe nucleus; EWcp, the
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Keywords: OFT، آزمون میدان باز; LA, low anxiety; HA, high anxiety; 6-OHDA, 6-hydroxydopamine; EPM, elevated plus maze; MFB, medial forebrain bundle; OFT, open field test; PD, Parkinson’s disease; SNc, substantia nigra compactaAnxiolytic; Parkinson’s disease; Non-motor symptom; Elevated
Keywords: OFT، آزمون میدان باز; BDNF, brain-derived neurotrophic factor; EPM, elevated plus maze; FST, forced swimming test; MS, maternal separation; NHI, neonatal hypoxia-ischemia; NMS, no maternal separation; OFT, open field test; PND, postnatal day; SYN, synaptophysinAnxiety; BDFN; D
Keywords: OFT، آزمون میدان باز; LE, Long Evans; SD, Sprague Dawley; TWM, trauma witness model; LD, light-dark test; OFT, open field test; EPM, elevated plus maze; RAWM, radial arm water maze; FST, forced swim testTrauma witness model; Anxiety; Depression; Stress
Keywords: OFT، آزمون میدان باز; Orx1R, orexin receptor-1; Orx2R, orexin receptor-2; SI, social interaction; RS, restraint stress; OFT, open field test; FST, forced swim test; icv, intracerebroventricular; PeF, perifornical hypothalamus; DMH, dorsomedial hypothalamus; LH, lateral hypotha
Keywords: OFT، آزمون میدان باز; LNT, lentinan; TST, tail suspension test; FST, forced swim test; OFT, open field test; PFC, prefrontal cortex; MDD, Major depressive disorder; Dectin-1, Dendritic cell-associated C-type lectin-1; p-GluR1(S845), phosphorylation of GluR1 S845; AMPA, α-amino
Keywords: OFT، آزمون میدان باز; BrdU, ((+)-5-bromo-2-deoxyuridine); GFP, green fluorescent protein; HC, Home-cage; L/D, light/dark; OFT, open field test; Rag2, recombination activating gene 2; SD, social defeat; TST, tail suspension test; UBC, human ubiquitin CLymphocytes; Psychological
Use of haloperidol and risperidone in highly aggressive Swiss Webster mice by applying the model of spontaneous aggression (MSA)
Keywords: OFT، آزمون میدان باز; MSA, model of spontaneous aggression; AgR, aggressive mice; TST, tail suspension test; OFT, open field test; AgD, subordinate mice; PAB, pattern of aggressive behavior; BTT, before treatment; LDT, last day of treatment; PTD, pharmacological treatment disc
Mice deficient for wild-type p53-induced phosphatase 1 display elevated anxiety- and depression-like behaviors
Keywords: OFT، آزمون میدان باز; CUMS, chronic unpredictable mild stress; EOM, elevated zero maze test; FST, forced swimming test; MAPK, mitogen-activated protein kinase; OFT, open field test; PPM1D, Mg2+/Mn2+-dependent, 1D; SPT, sucrose preference test; SSRIs, selective serotonin reupta
Social isolation differentially affects anxiety and depressive-like responses of bulbectomized mice
Keywords: OFT، آزمون میدان باز; OBX, olfactory bulbectomy; OFT, open field test; NSF, novelty suppressed feeding; FST, forced-swimming test; SSRIs, selective serotonin reuptake inhibitors; NRIs, noradrenaline reuptake inhibitorsBulbectomy; Social isolation; Depression; Anxiety; Behaviou
Chronic adrenocorticotrophic hormone treatment alters tricyclic antidepressant efficacy and prefrontal monoamine tissue levels
Keywords: OFT، آزمون میدان باز; Treatment resistant depression; Monoamine; Corticosterone; Animal model; Adrenocorticotrophic hormoneACTH, adrenocorticotrophic hormone; FST, forced swim test; HPA, hypothalamic-pituitary-adrenal; OFT, open field test; PFC, prefrontal cortex; TRD, treatme
Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice
Keywords: OFT، آزمون میدان باز; OFT, open field test; EPM, elevated-plus maze; FST, forced swim test; DG, dentate gyrus; DCX, doublecortinExercise; Hippocampus; Anxiety; Depression; Neurogenesis
Swimming exercise ameliorates depression-like behaviors induced by prenatal exposure to glucocorticoids in rats
Keywords: OFT، آزمون میدان باز; Glucocorticoid; Prenatal stress; Swimming exercise; DepressionDEX, dexamethasone; GCs, glucocorticoids; HPA, hypothalamic–pituitary–adrenal; OFT, open field test
Fructus Aurantii induced antidepressant effect via its monoaminergic mechanism and prokinetic action in rat
Keywords: OFT، آزمون میدان باز; FRA, Fructus Aurantii; FST, forced swimming test; OFT, open field test; FD, functional dyspepsia; IBS, irritable bowel syndromeFructus Aurantii; Antidepression; Prokinetics; Monoaminergic mechanism
Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission
Keywords: OFT، آزمون میدان باز; 5-HT, 5-hydroxytryptamine, serotonin; CB1R, cannabinoid CB1 receptor; Delta-9-THC, (-)-trans-delta(9)-tetrahydrocannabinol; DR, dorsal raphe; FAAH, fatty acid amide hydrolase; MAGL, monoacylglycerol lipase; FST, forced swim test; OFT, open field test; WAY
Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests
Keywords: OFT، آزمون میدان باز; CNS, central nervous system; OFT, open field test; EPM, elevated plus maze; FST, forced swim test; DA, dopamine; DZP, diazepam; DMI, desipramine; AMP, amphetamine; HCMA, homecage monitoring apparatus; APO, apomorphineBehavioural pharmacology; Elevated plu
Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice
Keywords: OFT، آزمون میدان باز; neurogenesis; angiogenesis; VEGF; depression; exerciseBrdU, 5-bromodeoxyuridine; CUS, chronic unpredictable stress; DG, dentate gyrus; DMSO, dimethylsulfoxide; FST, forced swim test; IGF-1, Insulin-like growth factor 1; OFT, open field test; PBS, phosphat
Distance from source of reward as a marker for extinction-induced “despair”: Modulation by the antidepressants clomipramine and citalopram
Keywords: OFT، آزمون میدان باز; ANOVA, analysis of variance; HPA, hypothalamus-pituitary-adrenal; MD, major depression; OFT, Open Field Test; RTE, resistance to extinction; SEM, standard error of the mean; SSRI, serotonin reuptake inhibitordepression model; extinction; despair; antidepr
Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice
Keywords: OFT، آزمون میدان باز; BDNF, brain-derived neurotrophic factor; FST, forced-swimming test; TST, tail suspension test; TCA, tricyclic antidepressants; CoA, coenzyme A; HD, Huntington disease; OFT, open field test; BSA, bovine serum albumin; pAb, polyclonal antibody; HSJ1b, heat
Hybridizing behavioral models: A possible solution to some problems in neurophenotyping research?
Keywords: OFT، آزمون میدان باز; OCD, obsessive compulsive disorder; FST, forced swim test; MWM, Morris water maze; OFT, open field test; NT, neurological tests; ST, swim testsBehavioral phenotyping; Experimental models; High-throughput testing; Research strategies; Single and multiple d
Antidepressant and anxiolytic effects of hydroalcoholic extract from Salvia elegans
Keywords: OFT، آزمون میدان باز; CNS, central nervous system; DZP, diazepam; EPM, elevated plus maze; FST, forced swimming test; IMI, imipramine; LDT, light–dark test; OFT, open field test; PTX, pycrotoxineAnxiety; Depression; Salvia elegans; Elevated plus-maze; Forced swimming test; Ope
Antidepressant drug induced alterations in binding to central dopamine transporter sites in the Wistar Kyoto rat strain
Keywords: OFT، آزمون میدان باز; ANOVA, analysis of variance; CPu, caudate–putamen; DA, dopamine; DAT, dopamine transporter; FST, Forced Swim Test; NE, norepinephrine; NAc, nucleus accumbens; OFT, Open Field Test; QAR, quantitative autoradiography; 5-HT, serotonin; S-D, Sprague–Dawley; V