Keywords: CAS; cycloartenol synthase; DDS; dammarenediol synthase; DMAPP; dimethylallyl diphosphate; DXP; 1-deoxy-d-xylulose 5-phosphate; FPP; farnesyl pyrophosphate; FPS; farnesyldiphosphate synthase; GAP; glyceraldehyde 3-phosphate; HMGR; 3-hydroxy-3-methylglutar
مقالات ISI (ترجمه نشده)
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Triterpenoid modulates the salt tolerance of lanosterol synthase deficient Saccharomyces cerevisiae, GIL77
Keywords: FID; flame ionization detector; GC; gas chromatography; LS; lanosterol synthase; OSCs; oxidosqualene cyclase; MES; 2-morpholinoethanesulfonic acid; BgbAS; β-amyrin synthase; BgLUS; lupeol synthase; SC; synthetic complete; S.E.M.; standard error of the me
Molecular cloning of an ester-forming triterpenoid: UDP-glucose 28-O-glucosyltransferase involved in saponin biosynthesis from the medicinal plant Centella asiatica
Keywords: BAS; β-amyrin synthase; BSA; bovine serum albumin; DTT; dithiothreitol; EST; expressed sequence tags; FPP; farnesyl diphosphate; LC-MS; liquid chromatography-mass spectrometry; MeJA; methyl jasmonate; OSC; oxidosqualene cyclase; PSPG; plant secondary
β-Amyrin synthase (EsBAS) and β-amyrin 28-oxidase (CYP716A244) in oleanane-type triterpene saponin biosynthesis in Eleutherococcus senticosus
Keywords: β-amyrin synthase; Oleanolic acid synthase; Saponin biosynthesis; Araliaceae; Eleutherococcus senticosus; CYP; cytochrome P450; OSC; oxidosqualene cyclase; GC-MS; gas chromatography-mass spectrometry; ORF; open reading frame; EsBAS; Eleutherococcus sen
New insights into substrate folding preference of plant OSCs
Keywords: Oxidosqualene cyclase; Homology modelling; Residue coevolution; Substrate folding;
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors
Keywords: Oxidosqualene cyclase; Enzyme inhibitor; High energy intermediate; Arylpiperidine; Docking experiments
Overexpression of functional human oxidosqualene cyclase in Escherichia coli
Keywords: Oxidosqualene cyclase; E. coli; Expression and purification; Membrane protein; Triterpene cyclase;
Potential synergistic effects of Chinese herbal prescription FTZ components detected in blood towards hepatic lipid-modulating targets
Keywords: TCM; traditional Chinese medicine; UPLC/Q-TOF-MS; ultra-performance liquid chromatography/quadruple-time-of-flight mass-spectrometry; RC; Rhizoma Coptidis; RSM; Radix Salvia Miltiorrhiza; TC; total cholesterol; TG; total triglyceride; LDL-C; low density l
Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway
Keywords: Saccharomyces cerevisiae; Ergosterol; Erg7; Erg27; 3-keto reductase; Oxidosqualene cyclase;
Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors
Keywords: Oxidosqualene cyclase; Enzyme inhibitor; High energy intermediate; Secosteroid; Species selectivity
Molecular characterization of an oxidosqualene cyclase that yields shionone, a unique tetracyclic triterpene ketone of Aster tataricus
Keywords: BARS; baruol synthase; BAS; β-amyrin synthase; BOS; baccharis oxide synthase; CAS; cycloartenol synthase; FRS; friedelin synthase; LAS; lanosterol synthase; LUP; lupeol synthase; OSC; oxidosqualene cyclase; SHS; shionone synthase; Asteraceae; Evolution;
Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast
Keywords: Saccharomyces cerevisiae; Ergosterol; Erg7; Erg27; 3-keto reductase; Oxidosqualene cyclase; Protein-protein interaction
Characterization of a dammarenediol synthase in Centella asiatica (L.) Urban
Keywords: Dammarenediol synthase; Centella asiatica; Oxidosqualene cyclase
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: A model for the development of novel antiparasitic agents
Keywords: Oxidosqualene cyclase; Lanosterol synthase; Inhibitors; Antiparasitic agents
Squalene cyclase and oxidosqualene cyclase from a fern
Keywords: OSC, oxidosqualene cyclase; SC, squalene cyclase; SHC, squalene-hopene cyclase; CAS, cycloartenol synthaseHydroxyhopane synthase; Squalene cyclase; Oxidosqualene cyclase; Triterpene; Ferns; Adiantum capillus-veneris
Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase
Keywords: Oxidosqualene cyclase; Lanosterol synthase; Trypanosoma cruzi; Chagas disease; Truncated squalene derivatives
Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng
Keywords: OSC, oxidosqualene cyclase; G-Xmn, ginsenosideGinsenoside; Dammarenediol-II; (20S)-dammarenediol; Oxidosqualene cyclase; cDNA cloning; Panax ginseng
Molecular cloning and functional expression of a multifunctional triterpene synthase cDNA from a mangrove species Kandelia candel (L.) Druce
Keywords: Kandelia candel (L.) druce; Rhizophoraceae; Mangrove; Oxidosqualene cyclase; Multifunctional triterpene synthase; Lupeol; β-Amyrin; α-Amyrin;
Cloning and characterization of a cDNA encoding β-amyrin synthase from petroleum plant Euphorbia tirucalli L.
Keywords: Euphorbia tirucalli L.; Euphorbiaceae; Petroleum plant; Heterologous expression; Pichia pastoris; Oxidosqualene cyclase; Triterpenoid; β-Amyrin;