دانلود مقالات ISI درباره P-gp، P-glycoprotein + ترجمه فارسی

The ability of gallate and pyrogallol moieties of catechins to inhibit P-glycoprotein function

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; Rho-123, rhodamine-123; EGCG, (−)-epigallocatechin gallate; ECG, (−)-epicatechin gallate; EC, (−)-epicatechin; EGC, (−)-epigallocatechin; EGCG-3″-O-Me, (−)-epigallocatechin 3-(3″-O-methyl)gallate; EGCG-4″-O-Me, (−)-epigallocatechin 3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells

Keywords: P-gp، P-glycoprotein; CAR, constitutive androstane receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; KTZ, ketoconazole; P-gp, P-glycoprotein; PXR, pregnane X receptor; Rh123, rhodamine 123; RIF, rifampicin; SL, spironolactoneHepG2 cells; Cytotoxicity; P-glycoprotein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb–drug interactions

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; CYP, cytochrome P450; TSI, tanshinone I; TSA, tanshinone IIA; TSB, tanshinone IIB; CTS, cryptotanshinone; LC–MS/MS, liquid chromatography with tandem mass spectrometry; DART, direct analysis in real time; PEG 600, polyethylene glycol

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a quantification method for digoxin, a typical P-glycoprotein probe in clinical and non-clinical studies, using high performance liquid chromatography–tandem mass spectrometry: The usefulness of negative ionization mode to avoid competitive

Keywords: P-gp، P-glycoprotein; DGX, digoxin; P-gp, P-glycoprotein; IA, immunoassay; LC/MS/MS, liquid chromatography–tandem mass spectrometry; FDA, the Food and Drug Administration; ITC, the International Transporter Consortium; DDI, drug–drug interaction; TDM, therapeutic drug monitori

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells

Keywords: P-gp، P-glycoprotein; MDR, multiple drug resistance; P-gp, P-glycoprotein; Dox, doxorubicin; PDI, polydispersity index; NP, nanoparticle; PCI, photochemical internalization; TPGS, d-alpha-tocopheryl poly(ethylene glycol) 1000 succinate; PPLA, porphyrin-PLA; PPLA-NPs, porphyrin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Suppression of multidrug resistance by treatment with TRAIL in human ovarian and breast cancer cells with high level of c-Myc

Keywords: P-gp، P-glycoprotein; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; MDR, multidrug resistance; P-gp, P-glycoprotein; DR, death receptor; c-FLIP, cellular FLICE [FADD (Fas-associated death domain)-like interleukin 1β-converting enzyme]-inhibitory protein; DISC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Transcriptional suppression of breast cancer resistance protein (BCRP) by wild-type p53 through the NF-κB pathway in MCF-7 cells

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; ABC, ATP-binding cassette; BCRP, Breast cancer resistance protein; MRP, multidrug resistance-associated protein; P-gp, P-glycoprotein; NF-κB, nuclear factor kappa-B; RNAi, RNA interference; wt-p53, wild-type p53; PBS, phosphate

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

MDR1 gene polymorphisms and response to acute risperidone treatment

Keywords: P-gp، P-glycoprotein; MDR1, multidrug resistant protein 1; BMI, body mass index; CYP2D6, cytochrome P450 2D6; P-gp, P-glycoprotein; BBB, blood–brain barrier; BPRS, Brief Psychiatric Rating Scale; CGI, Clinical Global Impression; BARS, Barnes Akathisia Rating Scale; SAS, Simpso

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Placental transport and in vitro effects of Bisphenol A

Keywords: P-gp، P-glycoprotein; BPA, Bisphenol A; TEER, transepithelial electrical resistance; IEMA, immunoenzymometric assay; P-gp, P-glycoprotein; P, permeability; Pe, apparent permeabilityBisphenol A; Fetal exposure; Placental transport; In vitro; Endocrine disruptor; Trophoblasts; D

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

In vitro modulation of ABCB1/P-glycoprotein expression by polyphenols from Mangifera indica

Keywords: P-gp، P-glycoprotein; Calcein-AM, calcein acetoxymethylester; CsA, cyclosporine A; CYP, cytochrome P-450; CTCH, catechin; DRB, 1-d-ribofuranosylbenzimidazole; GA, gallic acid; MG, mangiferin; MSBE, mango stem bark extract; NTR, norathyriol; P-gp, P-glycoprotein; QCT, quercetin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506)

Keywords: P-gp، P-glycoprotein; SchE, Schisandra sphenanthera extract; WZ, Wuzhi Tablet; FK506, Tacrolimus; FK520, Ascomycin; IS, internal standard; P-gp, P-glycoprotein; CYP3A, cytochrome p450 3A; Tmax, time to peak blood concentration; Cmax, peak blood concentration; AUC, area under t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; PDT, photodynamic therapy; ROS, reactive oxygen species; AOT, Aerosol-OTChemotherapy; Nanoparticles; Photosensitizer; Drug efflux; Drug resistance; Reactive oxygen species

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Cryptocaryone, a Natural Dihydrochalcone, Induces Apoptosis in Human Androgen Independent Prostate Cancer Cells by Death Receptor Clustering in Lipid Raft and Nonraft Compartments

Keywords: P-gp، P-glycoprotein; prostate; prostatic neoplasms; receptors, death domain; membrane microdomains; caspase 8FADD, Fas-associated death domain; FITC, fluorescein isothiocyanate; MβCD, methyl-β-cyclodextrin; P-gp, P-glycoprotein; PI, propidium iodide; PMSF, phenylmethylsulfony

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Matrix metalloproteinase-9 is required for tubular network formation and migration of resistant breast cancer cells MCF-7 through PKC and ERK1/2 signalling pathways

Keywords: P-gp، P-glycoprotein; MMP-9; Breast cancer cell line MCF-7; MDR1 phenotype; Cell migration; Tubular network; Signalling pathwaysMMP-9, matrix metalloproteinase-9; MMP-2, matrix metalloproteinase-2; MDR1, multidrug resistant1; P-gp, P-glycoprotein; hrMMP-9, human recombinant MM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

The alternatively spliced murine pregnane X receptor isoform, mPXRΔ171–211 exhibits a repressive action

Keywords: P-gp، P-glycoprotein; PXR, pregnane X receptor; CYP, cytochrome P450; MDR1, Multi Drug Resistance Protein 1; P-gp, P-glycoprotein; TSA, trichostatin A; RXR, retinoid X receptor; NR, nuclear receptors; h, human; m, mouse; mRNA, messenger ribonucleic acid; mP1, mPXR431; mP2, mPX

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Association between ABCB1 C3435T polymorphism and increased risk of cannabis dependence

Keywords: P-gp، P-glycoprotein; SNP, single nucleotide polymorphism; P-gp, p-glycoprotein; Δ9ΤΗC, Δ9 tetrahydrocannabinol; ABCB1, adenosine triphosphate (ATP)-binding cassette; MDR1, multi-drug resistance gene; MINI, Mini International Neuropsychiatric Interview; DSM-IV, Diagnostic Stat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure

Keywords: P-gp، P-glycoprotein; HE, hepatic encephalopathy; HAL, hepatic artery ligation; ALF, acute liver failure; BBB, blood–brain barrier; ET-1, endothelin-1; eNOS, endothelial nitric oxide synthase; P-gp, P-glycoprotein; vWF, von Willebrand factor; Occ, occludin; Cav1, caveolin-1Hep

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Association of ABCB1 gene polymorphisms with plasma lipid and apolipoprotein concentrations in the STANISLAS cohort

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; Apo, Apolipoprotein; BMI, Body Mass Index; Chol, Total Cholesterol; HDLc, HDL cholesterol; LD, Linkage Disequilibrium; LDLc, LDL cholesterol; MDR1, Multi Drug Resistance 1; P-gp, P-glycoprotein; SNPs, Single Nucleotide Polymorph

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Daunorubicin and doxorubicin inhibit the [11C]choline accumulation in cancer cells

Keywords: P-gp، P-glycoprotein; Doxorubicin; Daunorubicin; [11C]choline; [18F]FDG; PET; P-glycoprotein; Cancer cells[18F]FDG, 2-[18F]fluoro-2-deoxy-d-glucose; PET, positron emission tomography; P-gp, P-glycoprotein; DNR, Daunorubicin; DOX, Doxorubicin.

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Evaluation of the P-glycoprotein (Abcb1) affinity status of a series of morphine analogs: Comparative study with meperidine analogs to identify opioids with minimal P-glycoprotein interactions

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance proteins; P-gp, P-glycoprotein; MRP, multidrug resistance-associated proteins; Caco-2, epithelial human colon adenocarcinoma cell line; %MPE, percentage of maximal possible effect; AUEC, area under the percentage maximum possible

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

In vitro effects of Mangifera indica and polyphenols derived on ABCB1/P-glycoprotein activity

Keywords: P-gp، P-glycoprotein; Calcein-AM, calcein acetoxymethylester; CTCH, catechin; CYP, cytochrome P450; GA, gallic acid; KF, kaempferol; MG, mangiferin; MSBE, mango stem bark extract; NTR, norathyriol; P-gp, P-glycoprotein; QCT, quercetin; Rh-123, rhodamine-123; VCR, vincristine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin E TPGS

Keywords: P-gp، P-glycoprotein; TPGS, tocopheryl polyethylene glycol succinate; Rho, rhodamine 123; ABC, ATP-binding cassette; P-gp, P-glycoprotein; MDR1, multi-drug resistance gene; SAR, structure–activity relationship; Caco-2, human colon adenocarcinoma cell line; ER, efflux ratio; Pa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Nanoparticles for direct nose-to-brain delivery of drugs

Keywords: P-gp، P-glycoprotein; CSF, cerebrospinal fluid; %DA, % degree of deacetylation; N–B, nose-to-brain; HC-1, hypocretin-1; MW, molecular weight; PEG, polyethylene glycol; P-gp, P-glycoprotein; ROS, reactive oxygen species; TEM, transmission electron microscopyChitosan; Drug deliv

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice

Keywords: P-gp، P-glycoprotein; MPA, mycophenolic acid; MMF, mycophenolate mofetil; SNPs, single nucleotide polymorphisms; MDR1, multidrug resistance gene; P-gp, P-glycoprotein; CYP 3A, cytochrome P450 3A; Mrp2, multidrug resistance protein 2; OATPs, organic anion transporters; CsA, cyc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Increase in P-glycoprotein accompanied by activation of protein kinase Cα and NF-κB p65 in the livers of rats with streptozotocin-induced diabetes

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; MDR, multidrug resistance; P-gp, P-glycoprotein; STZ, streptozotocin; MRP, multidrug resistance-associated protein; OAT, organic anion transporter; OCT, organic cation transporter; PKC, protein kinase C; NF-κB, nuclear factor κB

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Down-regulation of P-glycoprotein expression by sustained intracellular acidification in K562/Dox cells

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; P-gp, P-glycoprotein; NHE1, Na+/H+ exchanger1; pHi, intracellular pH; Rh123, rhodamine 123; BCECF-AM, 2′, 7′-bis (2-carboxyethyl)-5 (6) -carboxyfluorescein acetoxymethylMultidrug resistance; P-glycoprotein; Na+/H+ exchanger1; In

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells

Keywords: P-gp، P-glycoprotein; MTT, methylthiazoletetrazolium; ATCC, American Type Culture Collection; FBS, fetal bovine serum; FCM, flow cytometry; MDA, malondialdehyde; SOD, superoxide dismutase; CAT, catalase; Lu, luteolin; Dox, doxorubicin; P-gp, P-glycoprotein; CI, confidence inte

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; P-gp, P-glycoprotein; PXR, Pregnane X Receptor; PBS, phosphate-buffered saline; DMSO, dimethyl sulfoxide.Piperine; P-gp; MDR1; Digoxin transport

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction

Keywords: P-gp، P-glycoprotein; BCA, bicinchoninic acid; Cav, caveolin; CsA, cyclosporin A; MACS, magnetic cell sorting; ID, immunodetection; IP, immunoprecipitation; MDCK, Madin-Darby canine kidney cells; MDR, multidrug resistance; P-gp, P-glycoprotein; PVDF, polyvinylidene difluoride;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line

Keywords: P-gp، P-glycoprotein; VP-16, etopside; P-gp, P-glycoprotein; 5-FU, 5-fluorouracil; MALDI-TOF, matrix assisted laser desorption ionisation-time of flight; PBS, phosphate buffered saline; ATCC, American type culture collection; 2D-DIGE, two dimensional-difference in gel electrop

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Permeability evaluation of peptidic HCV protease inhibitors in Caco-2 cells-correlation with in vivo absorption predicted in humans

Keywords: P-gp، P-glycoprotein; HCV, hepatitis C virus; AUC, area under the curve; HPLC, high performance liquid chromatography; AP, apical; BL, basolateral; P-gp, P-glycoprotein; BCRP, breast cancer resistant proteinHCV protease inhibitor; In vivo and in vitro pharmacokinetics; Human p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Hypoxia induces class III beta-tubulin gene expression by HIF-1α binding to its 3' flanking region

Keywords: P-gp، P-glycoprotein; TUBB3, Class III β-tubulin; P-gp, P-glycoprotein; TUBB, Class I β-tubulin; GFP, Green Fluorescent Protein; ChIP, Chromatin Immunoprecipitation; EPO, erythropoietin VEGF, vascular endothelial growth factor.Paclitaxel; Paclitaxel binding site; Drug resistan

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Insulin therapy restores impaired function and expression of P-glycoprotein in blood–brain barrier of experimental diabetes

Keywords: P-gp، P-glycoprotein; AGEs, advanced glycation end-products; BBB, blood–brain barrier; DM, diabetes mellitus; FBG, fasting blood glucose; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HBSS, Hank's balance salt solution; MDR, multidrug resistance; P-GP, P-glycoprotein; Q-PCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Inhibitory effect of docosahexaenoic acid (DHA) on the intestinal metabolism of midazolam: In vitro and in vivo studies in rats

Keywords: P-gp، P-glycoprotein; DHA, docosahexaenoic acid; CYP3A, cytochrome P450 isoenzyme; P-gp, P-glycoprotein; ERG, extraction ratio; F, oral bioavailability; AUC∞, areas under the whole blood concentration–time curve from zero to infinity; T1/2, half-life; Tmax, time to maximum pla

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Functional characterization of the Saccharomyces cerevisiae ABC-transporter Yor1p overexpressed in plasma membranes

Keywords: P-gp، P-glycoprotein; ABC, ATP binding cassette; TMD, Transmembrane domain; NBD, Nucleotide binding domain; P-gp, P-glycoprotein; CFTR, Cystic fibrosis transmembrane conductance regulator; MRP, Multidrug resistance associated protein; p-CMPS, p-chloromercuriphenylsulfonate; DC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

Keywords: P-gp، P-glycoprotein; SNP, single-nucleotide polymorphism; MDR1, multidrug resistance 1; P-gp, P-glycoprotein; ABC, ATP-binding cassette; OA, ovalbumin; OAR, renatured OA; OAN, native OA; CFTR, cystic fibrosis transmembrane conductance regulator; NBD, nucleotide binding domain

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function

Keywords: P-gp، P-glycoprotein; BHK, baby hamster kidney; Sf21, Spodoptera frugiperda 21; ABC, ATP binding cassette; MRP1, multidrug resistance protein 1; P-gp, P-glycoprotein; CFTR, cystic fibrosis trans-membrane conductance regulator; BSA, bovine serum albumin; NBD, nucleotide binding

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human

Keywords: P-gp، P-glycoprotein; DiOC2(3), 3,3′-diethyloxacarbocyanine iodide; PhA, pheophorbide A; CMFDA, 5-chloromethylfluorescein diacetate; Calcein-AM, calcein-acetoxymethyl ester; BCRP/Bcrp, breast cancer resistance protein; P-gp, p-glycoprotein; MRP/Mrp, multidrug resistance-associ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening

Keywords: P-gp، P-glycoprotein; 4d/24w, 4 days/24-well plate format; 12d/6w, 12 days/6-well plate format; BBB, blood-brain barrier; HTS, high throughput screening; P-gp, P-glycoprotein; BBCEC, bovine brain capillary endothelial cells; DMEM, Dulbecco’s modified Eagle’s medium; CS, calf s

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

P-Glycoprotein is not present in mitochondrial membranes

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; ABC, ATP-binding cassette; P-gp, P-glycoprotein; HB, homogenization buffer; RB, resuspension buffer; BSA, bovine serum albuminP-glycoprotein; P-gp; Multidrug resistance; Mitochondria; Cellular localization

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Impaired expression and function of breast cancer resistance protein (Bcrp) in brain cortex of streptozocin-induced diabetic rats

Keywords: P-gp، P-glycoprotein; Bcrp/ABCG2breast, cancer resistance protein; AG, aminoguanidine; MET, metformin; DM, diabetes mellitus; BBB, blood–brain barrier; STZ, streptozocin; P-gp, P-glycoprotein; MDR, multidrug resistance; MRPs, multidrug resistance-associated proteins; i.p., int

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Thyroxine (T4) transfer from CSF to choroid plexus and ventricular brain regions in rabbit: Contributory role of P-glycoprotein and organic anion transporting polypeptides

Keywords: P-gp، P-glycoprotein; TH, Thyroid hormone; T4, Thyroxine; T3, Triiodothyronine; CSF, Cerebrospinal fluid; CP, Choroid plexus; V-C, Ventriculo-cisternal; P-gp, P-glycoprotein; Oatps, Organic anion transporting polypeptide; CsA, Cyclosporine A; mrp1, Multidrug resistance protein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells

Keywords: P-gp، P-glycoprotein; CHOL, cholesterol; DPH, diphenylhexatriene; DXR, doxorubicin; EPC, egg phosphatidylcholine; HEPC, hydrogenated egg phosphatidylcholine; MDR, multidrug resistance; PEG, polyethylene glycol; P-gp, P-glycoprotein; Tf, transferrin; Tf-R, Tf receptorLiposome;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Wild-type class I β-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a β-tubulin mutation

Keywords: P-gp، P-glycoprotein; BCS, bovine calf serum; β2M, β-2-microglubulin; PDB, protein database bank; P-gp, P-glycoprotein; RT-PCR, reverse transcriptase-polymerase chain reaction; SDS–PAGE, SDS–polyacrylamide gel electrophoresisTaxol; Tubulin; Mutations; Microtubule; Drug-resista

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Quantitative study of the drug efflux kinetics from sensitive and MDR human breast cancer cells

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; CF, carbon fiber; CFME, carbon fiber microelectrode; P-gp, P-glycoprotein; MRP, Multidrug Resistance-Associated protein; ABC, members of the ATP-binding cassette; Dox, doxorubicin (also called Adriamycin); TMP, tetramethylpyrazi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Expression of drug transporters at the blood–brain barrier using an optimized isolated rat brain microvessel strategy

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; BBB, blood–brain barrier; Bcrp, breast cancer resistance protein; Gfap, glial fibrillary acidic protein; Mrp, multidrug resistance-associated protein; Oatp-2, organic anion transporting-polypeptide 2; P-gp, P-glycoprotein; qRT-P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Interaction of macrocyclic lactones with P-glycoprotein: Structure–affinity relationship

Keywords: P-gp، P-glycoprotein; ABA, abamectin; ABC, ATP-binding cassette; DOR, doramectin; EPR, eprinomectin; IVM, ivermectin; ML, macrocyclic lactone; MOX, moxidectin; P-gp, P-glycoprotein; Rho123, rhodamine 123; SEL, selamectin; VSP, valspodarP-glycoprotein; Macrocyclic lactones; Str

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a crucial role during ATP-dependent solute transport

Keywords: P-gp، P-glycoprotein; BHK, baby hamster kidney; Sf21, Spodoptera frugiperda 21; ABC, ATP binding cassette; MRP1, multidrug resistance protein; P-gp, P-glycoprotein; NBD, nucleotide binding domain; LTC4, leukotriene C4; 8-N3ATP, 8-azidoadenosine 5′-triphosphate; EGTA, ethylene

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

How can we best use structural information on P-glycoprotein to design inhibitors?

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; MDR, multidrug resistance; NBD, nucleotide-binding domain; P-gp, P-glycoprotein; QSAR, quantitative structure–activity relationships; TMD, transmembrane domainP-glycoprotein; Multidrug resistance; Cancer; Structure-based drug de

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of poly(ethylene glycol)-block-polylactide nanoparticles on hepatic cells of mouse: Low cytotoxicity, but efflux of the nanoparticles by ATP-binding cassette transporters

Keywords: P-gp، P-glycoprotein; SOD, superoxide dismutase; MDA, malondialdehyde; NOS, nitric oxide synthases; NO, nitric oxide; GSH, glutathione; GS-X, GSH conjugate; MDR, multidrug resistance; P-gp, P-glycoprotein; ABC, ATP-binding cassettePLA–PEG nanoparticles; ATP-binding cassette tr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه