
Substrate kringle-mediated catalysis by the streptokinase-plasmin activator complex: Critical contribution of kringle-4 revealed by the mutagenesis approaches
Keywords: Glu-PG; K1-K5CD (closed-conformer); Lys-PG; K1-K5CD (opened-conformer); K2-K5CD; K2K3K4K5CD; K3-K5CD; K3K4K5CD; K4K5CD; kringle 4 and kringle 5 conjugated with CD; K5CD; kringle 5 conjugated with CD; CD; catalytic domain of plasminogen; μPG; micr