دانلود مقالات ISI درباره P53 + ترجمه فارسی

Novel tacrine platinum(II) complexes display high anticancer activity via inhibition of telomerase activity, dysfunction of mitochondria, and activation of the p53 signaling pathway

Keywords: Platinum(II) complex; Tacrine; p53; Telomerase; Anticancer activity; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Ferrosenescence: The iron age of neurodegeneration?

Keywords: TE; transposable elements; IRP-2; iron regulatory protein-2; BACE-1; beta-secretase 1; APP; amyloid precursor protein; FPN; ferroportin; Tf; transferrin; TFR-1; transferrin receptor-1; IRE; iron-responsive elements; mtDNA; mitochondrial DNA; DNMT-3A and D

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

mTORC1 pathway in DNA damage response

Keywords: mTORC1 pathway; DNA damage response; PI3K-AKT; p53; SESTRINS; GATOR1; Autophagy; Mitochondria; Anticancer drugs;

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells

Keywords: AP4; Activating Protein 4; BAX; Bcl-2-associated X protein; Brd4; Bromodomain-containing protein 4; Brg1; Brahma-related gene-1; C2H2; Cys2-His2 zinc finger; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A gene; CDKN1A; Cyclin-Depe

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer's disease

Keywords: AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; Aβ; amyloid β peptides; ApoE; apolipoprotein E; APP; amyloid precursor proteins; BACE1; β-site APP cleaving enzyme 1; BIN1; bridging integrator 1; CBP; CREB-binding protei

دانلود رایگان متن کامل مقاله ISI 146 صفحه سال انتشار : 2018 سفارش ترجمه

d-Amino acid mutation of PMI as potent dual peptide inhibitors of p53-MDM2/MDMX interactions

Keywords: PMI; P53; MDM2/MDMX; d-Amino acid; Peptides; Tumor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionp53 alteration in morphologically normal/benign breast luminal cells in BRCA carriers with or without history of breast cancer

Keywords: BRCA carrier; p53; Normal/benign breast tissue; Triple-negative breast carcinoma; p53 signature;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

The cardiac glycoside convallatoxin inhibits the growth of colorectal cancer cells in a p53-independent manner

Keywords: Cancer; Apoptosis; Cell cycle; Convallatoxin; p53;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

CNPY2 promoted the proliferation of renal cell carcinoma cells and increased the expression of TP53

Keywords: Renal cell carcinoma; CNPY2; p53;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

MsrB3 deficiency induces cancer cell apoptosis through p53-independent and ER stress-dependent pathways

Keywords: Methionine sulfoxide; MsrB3; p53; ER stress; Cancer; Calcium homeostasis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Polμ deficiency induces moderate shortening of P53−/− mouse lifespan and modifies tumor spectrum

Keywords: DNA polymerase mu; Polμ; p53; NHEJ; DSB; Genomic instability; Sarcoma; Lymphoma;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

PAX5α and PAX5β mRNA expression in breast Cancer: Relation to serum P53 and MMP2

Keywords: Breast cancer; CA 15-3; MMP2; p53; PAX5α; PAX5β;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

HPV in esophageal cancerHuman papillomavirus infection increases the chemoradiation response of esophageal squamous cell carcinoma based on P53 mutation

Keywords: Esophageal cancer; HPV; Sensitivity; p53; Mechanism;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia reduces the E-cadherin expression and increases OSCC cell migration regardless of the E-cadherin methylation profile

Keywords: Proliferation; Oral cancer; p53; HIF-1α; Caspase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

PM2.5-induced alterations of cell cycle associated gene expression in lung cancer cells and rat lung tissues

Keywords: PM2.5; p53; p21; Cell division cycle 2; Cyclin-dependent kinase 2; Cyclin B;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Photoenhanced gene transfection by a curcumin loaded CS-g-PZLL micelle

Keywords: Curcumin; Photoenhanced; CS-g-PZLL; Codelivery; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Usp7 promotes medulloblastoma cell survival and metastasis by activating Shh pathway

Keywords: Usp7; Medulloblastoma; Shh; P53; CRISPR/Cas9;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70

Keywords: T-FISH; Genomic instability; Mouse genetics; Epistasis; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleGalantamine alleviates senescence of U87 cells induced by beta-amyloid through decreasing ROS production

Keywords: Alzheimer's disease; Beta-amyloid; U87 cell line; Galantamine; ROS; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Proapoptotic modification of substituted isoindolinones as MDM2-p53 inhibitors

Keywords: P53; MDM2; Protein-protein interaction; Computer modelling; Apoptosis; RDFQXKACQGFINF-UHFFFAOYSA-N; RYQVQNZUHMWWLH-UHFFFAOYSA-N; RCFNDSQQKSPXBD-UHFFFAOYSA-N; UVEVNAQWFWWPJC-UHFFFAOYSA-N; STFMKINHPFHVMP-UHFFFAOYSA-N; PDJLIWOLUDQPSK-UHFFFAOYSA-N; IJLSDVGVBQ

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

WDR5 positively regulates p53 stability by inhibiting p53 ubiquitination

Keywords: WDR5; p53; Ubiquitination; A549 cells;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

TP53 gene status is a critical determinant of phenotypes induced by ALKBH3 knockdown in non-small cell lung cancers

Keywords: Human AlkB homolog 3; Non-small cell lung cancer; TP53; p53; Apoptosis; 1-meA; 1-methyladenine; 3-meC; 3-methylcytosine; ALK; anaplastic lymphoma kinase; ALKBH3; AlkB homolog 3; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and RAD3-relat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effect of p53 on the viability of intervertebral disc nucleus pulposus cells under low glucose condition

Keywords: p53; Intervertebral disc (IVD); Nucleus pulposus (NP) cells; Low glucose;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

miR-34a sensitizes lung cancer cells to cisplatin via p53/miR-34a/MYCN axis

Keywords: Cisplatin; miR-34a; NSCLC; MYCN; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Partially Purified Gloriosa superba Peptides Inhibit Colon Cancer Cell Viability by Inducing Apoptosis Through p53 Upregulation

Keywords: Gloriosa superba; Partially purified peptide; Colon cancer; Apoptosis; p53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The induction of tumour suppressor protein P53 limits the entry of cells into the pluripotent inner cell mass lineage in the mouse embryo

Keywords: Tumour suppressor gene; Tumour related protein 53; P53; Inner cell mass; Epiblast; Pluripotency; NANOG; UTF1; OCT4; Caspase 3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Markers of the p53 pathway further refine molecular profiling in high-risk endometrial cancer: A TransPORTEC initiative

Keywords: Endometrial cancer; Molecular profiling; Prognosis; p53; p21; pp63; L1CAM; Pole;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Thyroid hormone induce a p53-dependent DNA damage through PI3K/Akt activation in sperm

Keywords: TH; thyroid hormone; PI3K; Phosphatidyl Inositol 3-kinase; MDM2; Murine Double Minute 2; TR; thyroxine receptor; TUNEL; terminal deoxynucleotidyl transferase dUTP nick-end labelling; MMP; mitochondrial membrane potential; Sperm motility; DNA damage; l-Thy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Magnolin inhibits prostate cancer cell growth in vitro and in vivo

Keywords: Magnolin; Prostate cancer; Proliferation; P53; Apoptosis; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

HOTAIR may regulate proliferation, apoptosis, migration and invasion of MCF-7 cells through regulating the P53/Akt/JNK signaling pathway

Keywords: HOTAIR; P53; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Endocrine actions of vitamin D in skin: Relevance for photocarcinogenesis of non-melanoma skin cancer, and beyond

Keywords: Vitamin D endocrine system; Vitamin D; Vitamin D receptor; Skin; Skin cancer; p53; Photocarcinogenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Binding kinetics of mutant p53R175H with wild type p53 and p63: A Surface Plasmon Resonance and Atomic Force Spectroscopy study

Keywords: p53; p63; Surface Plasmon Resonance; AFS; p53R175H; Protein-protein interaction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research ArticleInduction of senescence in cancer cells by 5′-Aza-2′-deoxycytidine: Bioinformatics and experimental insights to its targets

Keywords: 5′-Aza-2′-deoxycytidine; Bioinformatics; Multitarget; miRNA; p53; Cancer therapy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original articleProtective role of p53 in acetaminophen hepatotoxicity

Keywords: Acetaminophen; P53; JNK; Liver injury;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Protein kinase C downregulation induces senescence via FoxO3a inhibition in HCT116 and HEK293 cells

Keywords: Senescence; Protein kinase C; FoxO3a; ROS; p53; p21Cip1/WAF1; CK2; protein kinase CK2; DCFDA; dichlorofluorescein diacetate; DHE; dihydroethidium; DMEM; Dulbecco's modified Eagle's media; ECL; enhanced chemiluminescence; FoxO; forkhead homeobox type O; HA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mini-reviewThe role of the NORE1A tumor suppressor in Oncogene-Induced Senescence

Keywords: RASSF; HIPK2; PP1A; Retinoblastoma; p53; Ras; OIS; Oncogene-Induced Senescence; NORE1A; Novel Ras Effector 1A; Rb; Retinoblastoma Protein; PTM; Post-Translational Modification; EGFR; Epidermal Growth Factor Receptor; NF1; Neurofibromin 1; DAB2IP; DAB2 Int

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

CACUL1/CAC1 attenuates p53 activity through PML post-translational modification

Keywords: CACUL1; PML; SUMO; Ubiquitin; p53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewImmunohistochemical expression of p16, Ki-67 and p53 in cervical lesions - A systematic review

Keywords: Cervical intraepithelial neoplasia; Cancer; p16INK4; Ki-67; p53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of EVI1 transcription by the LEF1/β-catenin complex with p53-alteration in myeloid blast crisis of chronic myeloid leukemia

Keywords: EVI1; CML; Myeloid blast crisis; LEF1/β-catenin signaling; p53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

CRIF1 enhances p53 activity via the chromatin remodeler SNF5 in the HCT116 colon cancer cell lines

Keywords: CRIF1; SNF5; p53; Cell cycle arrest;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionB-cell posttransplant lymphoproliferative disorder isolated to the central nervous system is Epstein-Barr virus positive and lacks p53 and Myc expression by immunohistochemistry

Keywords: Posttransplant lymphoproliferative disorder; PTLD; Central nervous system lymphoma; p53; Myc;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of synergistic anti-tumor effects of doxorubicin and p53 via graphene oxide-polyethyleneimine nanocarriers

Keywords: Graphene oxide; Polyethyleneimine; Doxorubicin; p53; Successive inhibition;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Drp1 mediates compression-induced programmed necrosis of rat nucleus pulposus cells by promoting mitochondrial translocation of p53 and nuclear translocation of AIF

Keywords: Intervertebral disc degeneration; Nucleus pulposus cells; Compression; Programmed necrosis; Dynamin-related protein 1 (Drp1); p53; Apoptosis-inducing factor (AIF); LBP; low back pain; IDD; intervertebral disc degeneration; NP; nucleus pulposus; Drp1; dyna

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

COMMD9 promotes TFDP1/E2F1 transcriptional activity via interaction with TFDP1 in non-small cell lung cancer

Keywords: Non-small cell lung cancer; COMMD9; TFDP1/E2F1; p53;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticlePseudogene PDIA3P1 promotes cell proliferation, migration and invasion, and suppresses apoptosis in hepatocellular carcinoma by regulating the p53 pathway

Keywords: Long noncoding RNA; Pseudogene; Hepatocellular carcinoma; p53; HCC; hepatocellular carcinoma; LncRNA; long noncoding RNA; PDIA3P1; protein disulfide isomerase family A member 3 pseudogene 1; SiRNA; short interfering RNA; ShRNA; short hairpin RNA; qRT-PCR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence

Keywords: OSCC; oral cavity squamous cell carcinoma; FISH; fluorescence in situ hybridization; CI; chromosomal instable neoplasia; CIS; carcinoma in situ; LOH; loss of heterozygosity; MPTC; Maastricht Pathology Tissue Collection Department; CNV; copy number variati

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The sirtuin family members SIRT1, SIRT3 and SIRT6: Their role in vascular biology and atherogenesis

Keywords: Atherosclerosis; CVD; Sirtuin; SIRT1; SIRT3; SIRT6; Oxidative stress; Lipid metabolism; ABC; Adenosine triphosphate binding cassette; ABCG; ABC sub-family G member; ADP; Adenosine diphosphate; AMPK; Adenosine monophosphate-activated protein kinase; eNOS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchA phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours

Keywords: De-differentiated liposarcoma; HDM2; MDM2; p53; Pharmacokinetics; Pharmacodynamics; SAR405838; Solid tumours;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewMutant p53 as a target for cancer treatment

Keywords: p53; Cancer; Inhibitor; APR-246;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage and the bystander response in tumor and normal cells exposed to X-rays

Keywords: γ-H2AX; P53; ATM; Cyclins;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه