Keywords: β-سلولهای پانکراس; Diabetes; Isoflavones; Insulin resistance; Phytochemicals; Pancreatic β-Cells; DM; diabetes mellitus; T1DM; Type 1 diabetes mellitus; T2DM; Type 2 diabetes mellitus; DHD; dihydrodaidzein; O-Dma; O-desmethylangolensin; DHG; dihydrogenistein; 6-OH-O-Dma; 6
مقالات ISI β-سلولهای پانکراس (ترجمه نشده)
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Keywords: β-سلولهای پانکراس; Sulfonylureas; Insulin secretion; Type 2 diabetes; Pancreatic β-cells;
Deficiency of voltage-gated proton channel Hv1 attenuates streptozotocin-induced β-cell damage
Keywords: β-سلولهای پانکراس; Voltage-gated proton channel; Hv1; Pancreatic β-cells; ROS; Damage; Diabetes;
Substance P preserves pancreatic β-cells in type 1 and type 2 diabetic mice
Keywords: β-سلولهای پانکراس; Substance P; Type 1 diabetes; Type 2 diabetes; Pancreatic β-cells;
Isoferulic acid attenuates methylglyoxal-induced apoptosis in INS-1 rat pancreatic β-cell through mitochondrial survival pathways and increasing glyoxalase-1 activity
Keywords: β-سلولهای پانکراس; Isoferulic acid; Methylglyoxal; Pancreatic β-cells; Mitochondrial uncoupling protein 2; Glyoxalase-1;
A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy
Keywords: β-سلولهای پانکراس; Akt; protein kinase B; Ambra1; Autophagy And Beclin 1 Regulator 1; AMPK; 5â² AMP-activated protein kinase; Atg; autophagy related proteins; CAMKK; Ca2+/calmodulin-dependent protein kinase kinase; DFCP1; double FYVE-containing protein 1; DPP4; dipeptidyl
The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5â²-AMP-activated protein kinase in INS-1 β-cells under high glucose conditions
Keywords: β-سلولهای پانکراس; Glucagon-like peptide-1 (GLP-1); 5â²-AMP-activated protein kinase (AMPK); Autophagy; Pancreatic β-cells; High glucose;
Dysfunction of SERCA pumps as novel mechanism of methylglyoxal cytotoxicity
Keywords: β-سلولهای پانکراس; Pancreatic β-cells; Apoptosis; Carbonylation; SH-groups; Conformational changes; Molecular docking;
Glycine Transporter-1 and glycine receptor mediate the antioxidant effect of glycine in diabetic rat islets and INS-1 cells
Keywords: β-سلولهای پانکراس; AUCs; areas under the curve; BSA; bovine serum albumin; CAT; catalase; DCFH-DA; 2,7-Dichlorodi fluorescein; DM; diabetes mellitus; GlyR; glycine receptor; GlyT1; glycine transporter-1; GSH; glutathione; HG; high glucose; Nox; NADPH oxidase; OGTT; oral glu
Attenuation of high glucose induced apoptotic and inflammatory signaling pathways in RIN-m5F pancreatic β cell lines by Hibiscus rosa sinensis L. petals and its phytoconstituents
Keywords: β-سلولهای پانکراس; ROS; reactive oxygen species; EHRS; ethyl acetate fraction of ethanolic extract of Hibiscus; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NRU; Neutral Red uptake; AO/EB; Acridine orange/Ethidium bromide; iNOS; nitric oxide synthase;
Investigation of the role of ion channels in human pancreatic β-cell hubs: A mathematical modeling study
Keywords: β-سلولهای پانکراس; Hub cells; Pancreatic β-cells; Mathematical modeling; Gap junction coupling;
The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response
Keywords: β-سلولهای پانکراس; Adaptive antioxidant response; Pancreatic β-cells; Glucotoxicity; Lipotoxicity; Glucose-stimulated insulin secretion;
Insulinotropic and anti-apoptotic effects of nobiletin in INS-1D β-cells
Keywords: β-سلولهای پانکراس; Nobiletin; Pancreatic β-cells; Insulin secretion; β-Cell apoptosis; ER stress;
The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1
Keywords: β-سلولهای پانکراس; NR4A1; nuclear receptor subfamily 4, group A member 1; 8-OHdG; 8-hydroxy deoxyguanosine; DAPI; 4,6-diamidino-2-phenyindole; ROS; reactive oxygen species; Caspase 3; cysteinyl aspartate specific proteinase 3; WT1; Wilms' tumor gene 1; SIRT1; Sirtuin type 1
Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells
Keywords: β-سلولهای پانکراس; Mitochondrial metabolism; Pancreatic β-cells; Insulin secretion;
Sphallerocarpus gracilis polysaccharide protects pancreatic β-cells via regulation of the bax/bcl-2, caspase-3, pdx-1 and insulin signalling pathways
Keywords: β-سلولهای پانکراس; Sphallerocarpus gracilis polysaccharide; Pancreatic β-cells; Anti-apoptotic; Insulin secretagogue actions;
Protective effects of SGLT2 inhibitor luseogliflozin on pancreatic β-cells in obese type 2 diabetic db/db mice
Keywords: β-سلولهای پانکراس; Pancreatic β-cells; SGLT2 inhibitor; β-cell mass and function;
Etoposide induces pancreatic β-cells cytotoxicity via the JNK/ERK/GSK-3 signaling-mediated mitochondria-dependent apoptosis pathway
Keywords: β-سلولهای پانکراس; Etoposide; Pancreatic β-cells; Apoptosis; Mitochondria; JNK/ERK; GSK-3;
Effects of Bisphenol A on ion channels: Experimental evidence and molecular mechanisms
Keywords: β-سلولهای پانکراس; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; BPA; Bisphenol A; ER; estrogen receptor; CFTR; cystic fibrosis transmembrane conductance regulator; GABAA; gamma-aminobutyric acid type A; EDCs; endocrine-disrupting chemicals; GPR30 or GPER; G-pr
Benzimidazole derivatives protect against cytokine-induced apoptosis in pancreatic β-Cells
Keywords: β-سلولهای پانکراس; Pancreatic β-cells; Benzimidazole; Cytokines; Apoptosis; Glucose-stimulated insulin secretion;
ATF6β regulates the Wfs1 gene and has a cell survival role in the ER stress response in pancreatic β-cells
Keywords: β-سلولهای پانکراس; ATF6; ER stress; Insulin; Proinsulin; Pancreatic β-cells;
Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling
Keywords: β-سلولهای پانکراس; Nephrin signaling; Pancreatic β-cells; PI3K-Akt survival signaling; High glucose; Nephrin internalization; Diabetic mouse pancreatic islets;
N-Acyl taurines trigger insulin secretion by increasing calcium flux in pancreatic β-cells
Keywords: β-سلولهای پانکراس; N-Arachidonoyl taurine; N-Oleoyl taurine; Insulin secretion; Transient receptor potential vanilloid receptor 1 (TRPV1); Pancreatic β-cells;
Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice
Keywords: β-سلولهای پانکراس; STZ; streptozotocin; PARP; poly(ADP-ribose) polymerase; NAD+; nicotinamide adenine dinucleotide; TUNEL; TdT-mediated dUTP Nick-End Labeling; HD-STZ; high-dose streptozotocin; MD-STZ; medium-dose streptozotocin; LD-STZ; low-dose streptozotocin; Pancreatic
Alternanthera paronychioides protects pancreatic β-cells from glucotoxicity by its antioxidant, antiapoptotic and insulin secretagogue actions
Keywords: β-سلولهای پانکراس; MEAP; methanol extracts from Alternanthera paronychioides; EEAP; ethanol extracts from Alternanthera paronychioides; WEAP; water extracts from Alternanthera paronychioides; TEAC; Trolox equivalent antioxidant capacity; ORAC; oxygen radical absorbance capa
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
Keywords: β-سلولهای پانکراس; Whole organ decellularization; Extracellular matrix scaffold; Tissue and organ engineering; Pancreatic β-cells;
In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated β-cell dysfunction during the progression of type-2 diabetes
Keywords: β-سلولهای پانکراس; Type 2 diabetes; Pancreatic β-cells; ER stress; AMPK; ATF3; In vivo knockdown;
Empirical mathematical model for dynamic manganese-enhanced MRI of the murine pancreas for assessment of β-cell function
Keywords: β-سلولهای پانکراس; Manganese-enhanced MRI; Diabetes; Rodent pancreas; Pancreatic β-cells;
Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading
Keywords: β-سلولهای پانکراس; Autoimmune disease; Diabetes; T lymphocytes; Epitope spreading; T cell activation; Tolerance; Immunoregulation; Insulin; Pancreatic β-cells; EAE; experimental autoimmune encephalomyelitis; GAD65; glutamate decarboxylase 65 kDa; IGRP; islet-specific gluco
Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line
Keywords: β-سلولهای پانکراس; Glucagon-like peptide-1; Exendin-4; Lipotoxicity; Pancreatic β-cells; Diabetes;
Differential effects of propofol and isoflurane on glucose utilization and insulin secretion
Keywords: β-سلولهای پانکراس; Isoflurane; Propofol; KATP channels; Insulin secretion; Pancreatic β-cells;
ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells
Keywords: β-سلولهای پانکراس; ARNT; aryl hydrocarbon receptor nuclear translocator; ChREBP; carbohydrate responsive element-binding protein; ChIP; chromatin immunoprecipitation; ChoRE; carbohydrate-responsive element; FAS; fatty acid synthase; GcK; glucokinase; GFP; green fluorescent
Extracellular ATP-induced nuclear Ca2+ transient is mediated by inositol 1,4,5-trisphosphate receptors in mouse pancreatic β-cells
Keywords: β-سلولهای پانکراس; Inositol 1,4,5-trisphosphate (IP3) receptors; Pancreatic β-cells; Nuclear Ca2+ transient; ATP;
Topological entropy and the controlled effect of glucose in the electrical activity of pancreatic β-cells
Keywords: β-سلولهای پانکراس; 89.65.Gh; 89.70.Cf; 89.75.Fb; 05.45.Ac; Pancreatic β-cells; Glucose; Bursting activity; Kneading theory; Topological entropy; Chaos control;
Comparison of the effect of individual saturated and unsaturated fatty acids on cell growth and death induction in the human pancreatic β-cell line NES2Y
Keywords: β-سلولهای پانکراس; Saturated fatty acids; Unsaturated fatty acids; Trans fatty acids; Cell growth; Cell death induction; Caspase-2; Pancreatic β-cells; NES2Y cells;
Apoptosis in the pathophysiology of diabetes mellitus
Keywords: β-سلولهای پانکراس; Akt; protein kinase B; Bad; Bcl-2 antagonist of cell death; Bax; Bcl-2 antagonist X; Bcl; B-cell leukaemia/lymphoma; FADD; Fas-associated death domain containing protein; FFA; free fatty acid; IAPP; islet amyloid polypeptide; JNK; c-Jun N-terminal kinase;
Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein
Keywords: β-سلولهای پانکراس; Thioredoxin; Pancreatic β-cells; Diabetes; Apoptosis; Insulin secretion; RAB27A; Microarray; Transcriptional repressor;