دانلود مقالات ISI درباره بیماری پارکینسون + ترجمه فارسی

A new target for Parkinson's disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats

Keywords: بیماری پارکینسون; Parkinson's disease; ER stress; Endoplasmic reticulum; Drug discovery; Small molecules; Medicinal chemistry;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleNeuroprotection by freshwater clam extract against the neurotoxin MPTP in C57BL/6 mice

Keywords: بیماری پارکینسون; Parkinson's disease; Freshwater clam extract; MPTP; Neuroprotection; Neurotrophic factor; Inflammation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Selective A2A receptors blockade reduces degeneration of substantia nigra dopamine neurons in a rotenone-induced rat model of Parkinson's disease: A histological study

Keywords: بیماری پارکینسون; Parkinson's disease; Dopamine; Histological stain; Immunohistochemical stain; Rotenone; Adenosine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Nogo-receptor 1 antagonization in combination with neurotrophin-4/5 is not superior to single factor treatment in promoting survival and morphological complexity of cultured dopaminergic neurons

Keywords: بیماری پارکینسون; FFRT; free-floating roller tube; GDNF; glial cell line-derived neurotrophic factor; GFAP; glial fibrillary acidic protein; HBSS; Hank's balanced salt solution; HS; horse serum; LINGO-1; leucine rich repeat neuronal protein 1; MAP2; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleValproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy

Keywords: بیماری پارکینسون; PD; Parkinson's disease; DAergic; dopaminergic; SNpc; substantia nigra pars compacta; VPA; valproic acid; HDAC; histone deacetylase; GABA; gamma aminobutyric acid; MPTP; 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine; GDNF; glial cell line-derived neurot

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Distinct patterns of imprecise consonant articulation among Parkinson's disease, progressive supranuclear palsy and multiple system atrophy

Keywords: بیماری پارکینسون; Parkinson's disease; Atypical Parkinsonian syndromes; Voice onset time; Dysarthria; Speech disorders; Acoustic analysis; Perceptual assessment;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

JWA antagonizes paraquat-induced neurotoxicity via activation of Nrf2

Keywords: بیماری پارکینسون; Nrf2; nuclear factor erythroid 2-related factor 2; PQ; paraquat; PD; Parkinson's disease; SA; saline; ROS; reactive oxygen species; JWA-nKO; neuron-specific JWA knockout mice; JWA-nWT; neuron-specific JWA knockout age-matched wild-type mice; SNpc; subst

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions

Keywords: بیماری پارکینسون; Parkinson's disease; Alzheimer's disease; 5-Hydroxy-2-benzylidene-1-tetralones; A1 adenosine receptor antagonists; A2A adenosine receptor antagonists;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Daily consumption of methylene blue reduces attentional deficits and dopamine reduction in a 6-OHDA model of Parkinson's disease

Keywords: بیماری پارکینسون; LID; l-dopa-induced dyskinesia; MB; methylene blue; NHS; normal horse serum; PB; phosphate buffer; PBS; phosphate-buffered saline; PD; Parkinson's disease; PFA; paraformaldehyde; SNc; substantia nigra; TH; tyrosine hydroxylase; VTA; ventral tegmental ar

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat

Keywords: بیماری پارکینسون; Acetyl-l-carnitine; Parkinson's disease; 6-Hydroxydopamine; Apoptosis; Oxidative stress; Neuroinflammation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Subcellular expression of aquaporin-4 in substantia nigra of normal and MPTP-treated mice

Keywords: بیماری پارکینسون; AQP4; aquaporin-4; DA; dopaminergic; GFAP; glial fibrillary acidic protein; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNpc; substantia nigra pars compacta; TH; tyrosine hydroxylase; aquaporin-4; a

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The role of MACF1 in nervous system development and maintenance

Keywords: بیماری پارکینسون; MACF1; microtubule actin crosslinking factor 1; ACF7; actin crosslinking factor 7; BPAG1; bullous pemphigoid antigen 1; PD; Parkinson's disease; ASD; autism spectrum disorder; ABD; actin binding domain; CH1; calponin homology domain 1; CH2; calponin hom

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Wnt/β-catenin signaling plays an essential role in α7 nicotinic receptor-mediated neuroprotection of dopaminergic neurons in a mouse Parkinson's disease model

Keywords: بیماری پارکینسون; Alpha7 nicotinic receptors; Parkinson's disease; Dopamine; Knockout; Wnt signaling pathway; Mouse;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleAssociation between PARK16 and Parkinson's disease: A meta-analysis

Keywords: بیماری پارکینسون; Parkinson's disease; PARK16; RAB7L1; Meta-analysis; LRRK2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportPrelimbic α1-adrenoceptors are involved in the regulation of depressive-like behaviors in the hemiparkinsonian rats

Keywords: بیماری پارکینسون; Prelimbic cortex; α1-Adrenoceptors; Depression; Parkinson's disease; Rat;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Subthalamic oscillations and phase amplitude coupling are greater in the more affected hemisphere in Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Beta oscillations; Tremor; Phase amplitude coupling; Deep brain stimulation; Phenotypes;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Depressive-like neurochemical and behavioral markers of Parkinson's disease after 6-OHDA administered unilaterally to the rat medial forebrain bundle

Keywords: بیماری پارکینسون; APO; apomorphine; DA; dopamine; HIP; hippocampus; 5-HT; serotonin; LC; locus coeruleus; MFB; medial forebrain bundle; NA; noradrenaline; 6-OHDA; 6-hydroxydopamine; PD; Parkinson's disease; PFC; prefrontal cortex; SN; substantia nigra; STR; striatum; Asy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

A natural product from Cannabis sativa subsp. sativa inhibits homeodomain-interacting protein kinase 2 (HIPK2), attenuating MPP+-induced apoptosis in human neuroblastoma SH-SY5Y cells

Keywords: بیماری پارکینسون; Homeodomain-interacting protein kinase 2; Parkinson's disease; Cannabis sativa subsp. sativa; (Z)-methyl p-hydroxycinnamate; Apoptosis; SH-SY5Y cells;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; L-DOPA; Transplant; Stem cell; Dyskinesia; Immune response;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DCTN1-related neurodegeneration: Perry syndrome and beyond

Keywords: بیماری پارکینسون; Atypical parkinsonism; DCTN1; Dynactin; FTD; Genetics; TDP-43; Perry syndrome; PSP; Review; ALS; amyotrophic lateral sclerosis; CAP-Gly; cytoskeleton-associated protein, glycine-rich; DCTN1; dynactin 1; FTD; frontotemporal dementia; HD; Huntington's dis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

Keywords: بیماری پارکینسون; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; HVA; homovanilic acid; MPP+; 1-methyl-4-phenylpyridinium ion; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's disease; SN; substantia nigra; SNc; substantia nigra pars compacta; SNr; s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Intrastriatal injection of ionomycin profoundly changes motor response to l-DOPA and its underlying molecular mechanisms

Keywords: بیماری پارکینسون; AIMs; abnormal involuntary movement scale; ANOVA; analysis of variance; CPU; striatum; CREB; cAMP response element-binding protein; DARPP32; dopamine- and c-AMP-regulated phosphoprotein of 32 kDa; DREAM; calcium-binding protein downstream regulatory elem

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Orobol derivatives and extracts from Cudrania tricuspidata fruits protect against 6-hydroxydomamine-induced neuronal cell death by enhancing proteasome activity and the ubiquitin/proteasome-dependent degradation of α-synuclein and synphilin-1

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydomamine; PD; Parkinson's disease; PARP; poly (ADP-ribose) polymerase; ROS; reactive oxygen species; UPP; ubiquitin-proteasome pathway; UPS; ubiquitin-proteasome system; CTE50; 50% ethanol extract from Cudrania tricuspidata fruits; OB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Vocal emotion decoding in the subthalamic nucleus: An intracranial ERP study in Parkinson's disease

Keywords: بیماری پارکینسون; Deep brain stimulation; Emotional prosody; Local field potentials; Parkinson's disease; Subthalamic nucleus; AC; anterior commissure; BG; basal ganglia; CT; computed tomography; DBS; deep brain stimulation; ERP; event-related potential; f0; fundamental

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Exposure to an enriched environment facilitates motor recovery and prevents short-term memory impairment and reduction of striatal BDNF in a progressive pharmacological model of parkinsonism in mice

Keywords: بیماری پارکینسون; Enriched environment; Reserpine; Parkinson's disease; Animal model; BDNF;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Vocalic transitions as markers of speech acoustic changes with STN-DBS in Parkinson's Disease

Keywords: بیماری پارکینسون; Dysarthria; Parkinson's disease; Deep brain stimulation; Speech acoustics; Speech intelligibility; F2 slope;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood-brain barrier dysfunction in vitro

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; AP; activating peptide; BBB; blood-brain barrier; BMEC; brain microvascular endothelial cell; DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylenediaminetetraacetic acid; ERK; extracellular signal-regulated kinase; FBS

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Full-length ArticleGPER activation is effective in protecting against inflammation-induced nigral dopaminergic loss and motor function impairment

Keywords: بیماری پارکینسون; PD; Parkinson's disease; DA; dopaminergic; SNpc; substantia nigra pars compacta; LPS; lipopolysaccharide; ERs; estrogen receptors; ERα; estrogen receptors α; ERβ; estrogen receptors β; GPER; G protein-coupled estrogen receptor; MEM; Minimum Essentia

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Neuregulin-1 protects mouse cerebellum against oxidative stress and neuroinflammation

Keywords: بیماری پارکینسون; Nrg1; neuregulin-1; rNrg1β; recombinant Nrg1β; ErbB; epidermal growth factor receptor; LPS; lipopolysaccharides; CGNs; cerebellar granule neurons; AD; Alzheimer's disease; PD; Parkinson's disease; HD; Huntington's disease; ALS; amyotrophic lateral

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportThe effect of electroacupuncture on proteomic changes in the motor cortex of 6-OHDA Parkinsonian rats

Keywords: بیماری پارکینسون; Electroacupuncture; Parkinson's disease; 6-Hydroxydopamine; Motor cortex; Proteomics;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Early and progressive microstructural brain changes in mice overexpressing human α-Synuclein detected by diffusion kurtosis imaging

Keywords: بیماری پارکینسون; MRI; Diffusion kurtosis imaging; Substantia nigra; Striatum; Thalamus; TNWT-61; Parkinson's disease; Transgenic mice; Animal model;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Dieldrin-induced neurotoxicity involves impaired mitochondrial bioenergetics and an endoplasmic reticulum stress response in rat dopaminergic cells

Keywords: بیماری پارکینسون; Neurodegeneration; Parkinson's disease; Legacy pesticide; Dopamine; Oxidative stress; ATP production;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Disease-Specific Outcomes of Botulinum Toxin Injections for Neurogenic Detrusor Overactivity

Keywords: بیماری پارکینسون; Botulinum toxin; Overactive bladder; Neurogenic; Detrusor overactivity; Urinary incontinence; Parkinson's disease; Myelomeningocele; Multiple sclerosis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced neuroprotection with decellularized brain extracellular matrix containing bFGF after intracerebral transplantation in Parkinson's disease rat model

Keywords: بیماری پارکینسون; Decellularized brain extracellular matrix; Basic fibroblast growth factor; Parkinson's disease; Neuroprotection; Transplantation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier

Keywords: بیماری پارکینسون; BBB; blood brain barrier; CNS; central nervous system; PD; Parkinson's disease; BBMEC; bovine brain microvessel endothelial cells; HBMEC; human brain microvascular endothelial cells; TEER; transendothelial electrical resistance; JAMs; junctional adhesio

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

A Nigro−Vagal Pathway Controls Gastric Motility and Is Affected in a Rat Model of Parkinsonism

Keywords: بیماری پارکینسون; Neurology; Animal Model; Central Nervous System; Vagus; CTB; cholera toxin subunit B; DMV; dorsal motor nucleus of the vagus; DVC; dorsal vagal complex; ENS; enteric nervous system; GI; gastrointestinal; IR; immunoreactive; NMDA; N-methyl-d-aspartate; 6-O

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Imidazo[1,2-α]pyridines possess adenosine A1 receptor affinity for the potential treatment of cognition in neurological disorders

Keywords: بیماری پارکینسون; Alzheimer's disease; Parkinson's disease; Imidazo[1,2-α]pyridine analogues; Adenosine A1 and A2A receptor antagonists;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

The impact of metabotropic glutamate receptors into active neurodegenerative processes: A “dark side” in the development of new symptomatic treatments for neurologic and psychiatric disorders

Keywords: بیماری پارکینسون; Metabotropic glutamate receptors; Schizophrenia; Major depressive disorders; Alzhiemer's disease; Parkinson's disease; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

β-asarone and levodopa coadministration increases striatal levels of dopamine and levodopa and improves behavioral competence in Parkinson's rat by enhancing dopa decarboxylase activity

Keywords: بیماری پارکینسون; Parkinson's disease; Behavioral tests; Neurotransmitters; Dopa decarboxylase; β-asarone; Dopaminergic neurons;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Levodopa (L-DOPA) attenuates endoplasmic reticulum stress response and cell death signaling through DRD2 in SH-SY5Y neuronal cells under α-synuclein-induced toxicity

Keywords: بیماری پارکینسون; CNS; Central nervous system; D1* DRD1; DA receptor; D2* DRD2; DA receptor; DA; dopaminergic; LBs; Lewy bodies; L-DOPA; levodopa; LNs; Lewy neurites; PD; Parkinson's disease; Parkinson's disease; levodopa; SH-SY5Y neuronal cells; endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Metabotropic glutamate receptor 5 mediates the suppressive effect of 6-OHDA-induced model of Parkinson's disease on liver cancer

Keywords: بیماری پارکینسون; PD; Parkinson's disease; 6-OHDA; 6-hydroxydopamine; mGluR5; metabotropic glutamate receptor 5; TH; tyrosine hydroxylase; MPEP; 2-methyl-6-(phenylethyl)-pyridine; DHPG; (S)-3,5-dihydroxyphenylglycine; CREB; cAMP-response element binding protein; ERK; ext

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewDysregulated microRNAs in neural system: Implication in pathogenesis and biomarker development in Parkinson's disease

Keywords: بیماری پارکینسون; PD; Parkinson's disease; DA; dopaminergic; SN; substantia nigra; LRRK2; leucine repeat kinase 2; PINK1; PTEN-Induced Putative Kinase 1; ROS; reactive oxidative stress; AD; Alzheimer's disease; MPTP; methyl-4-phenyl-1,2,3,6-tetrahydropyridine; c/EBP-al

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Short- and long-term effects induced by repeated 6-OHDA intraventricular administration: A new progressive and bilateral rodent model of Parkinson's disease

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; ICV; intracerebroventricular; MFB; medial forebrain bundle; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PBS; phosphate buffer saline; PD; Parkinson's disease; SNpc; substantia nigra pars compacta; VTA; ventral tegmenta

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Changes in blood anti-oxidation enzyme levels in MPTP-treated monkeys

Keywords: بیماری پارکینسون; Parkinson's disease; MPTP; Oxidative stress; Monkey; Behavior; Antioxidant;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation

Keywords: بیماری پارکینسون; Maternal immune activation; Fetal programming; Offspring behavior; Dopaminergic; Neuron; Reward behavior; Motor behavior; Lipopolysaccharide; Midbrain; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice

Keywords: بیماری پارکینسون; 3α-diol; 5α-androstane-3α, 17β-diol; 3β-diol; 5α-androstane-3β, 17β-diol; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DHEA; dehydroepiandrosterone; DHP; 5α-dihydroprogesterone; DHT; dihydrotestost

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Identifying the presence of Parkinson's disease using low-frequency fluctuations in BOLD signals

Keywords: بیماری پارکینسون; Parkinson's disease; Resting-state functional magnetic resonance imaging; Amplitude of low-frequency fluctuations; Fractional amplitude of low-frequency fluctuations;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

A multilevel-ROI-features-based machine learning method for detection of morphometric biomarkers in Parkinson's disease

Keywords: بیماری پارکینسون; multilevel ROI features; support vector machine (SVM); magnetic resonance imaging (MRI); Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

A review of patient-specific gastrointestinal parameters as a platform for developing in vitro models for predicting the in vivo performance of oral dosage forms in patients with Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Gastrointestinal function; Gastrointestinal parameters; Oral dosage forms; Bio-predictive methods;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Effectiveness and safety of acupuncture in the treatment of Parkinson's disease: A systematic review and meta-analysis of randomized controlled trials

Keywords: بیماری پارکینسون; Acupuncture; Parkinson's disease; Randomized controlled trials; Systematic review; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه