دانلود مقالات ISI درباره بیماری پارکینسون + ترجمه فارسی

The behavioural and neuroprotective outcomes when 670 nm and 810 nm near infrared light are applied together in MPTP-treated mice

Keywords: بیماری پارکینسون; Parkinson's disease; Photobiomodulation; Substantia nigra; Open-field test;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Increased abundance of myeloid-derived suppressor cells and Th17 cells in peripheral blood of newly-diagnosed Parkinson's disease patients

Keywords: بیماری پارکینسون; Parkinson's disease; T-helper 17 cells; Myeloid-derived suppressor cells; Neuroinflammation;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Tctex1 plays a key role in the α-synuclein autophagy lysosomal degradation pathway

Keywords: بیماری پارکینسون; Tctex1; α-Synuclein; Autophagy; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Adamantyl- and other polycyclic cage-based conjugates of desferrioxamine B (DFOB) for treating iron-mediated toxicity in cell models of Parkinson's disease

Keywords: بیماری پارکینسون; Desferrioxamine B; Polycyclic cage compounds; Iron chelators; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Chronic eczematous dermatitis in patients with neurodegenerative diseases may be an early marker of bullous pemphigoid

Keywords: بیماری پارکینسون; Dementia; Alzheimer's disease; Stroke; Parkinson's disease; Eosinophilia; Neurodegenerative disease; Pruritus;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

The relationship between Impulse Control Disorders and cognitive dysfunctions in Parkinson's Disease: A meta-analysis

Keywords: بیماری پارکینسون; Parkinson's disease; Impulse Control Disorders; Cognitive deficit; Cognitive dysfunctions; Pathological gambling;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Cerebral metabolic change in Parkinson's disease patients with anxiety: A FDG-PET study

Keywords: بیماری پارکینسون; Parkinson's disease; Anxiety; FDG-PET; Prefrontostriatal pathways;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice

Keywords: بیماری پارکینسون; ACh; acetylcholine; BiVs; Botulinum neurotoxin-A-induced varicosities; BoNT-A; botulinum neurotoxin-A; BoNT-B; botulinum neurotoxin-B; BoNT-C; botulinum neurotoxin-C; ChAT; choline acetyltransferase; CPu; caudate-putamen; DA; dopamine; hemi-PD; hemisparki

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Polymorphism in MIR4697 but not VPS13C, GCH1, or SIPA1L2 is associated with risk of Parkinson's disease in a Han Chinese population

Keywords: بیماری پارکینسون; Parkinson's disease; GCH1; SIPA1L2; VPS13C; MIR4697; Single-nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

Keywords: بیماری پارکینسون; CHMs; Chinese herbal medicines; ATG; autophagy-related proteins; AD; Alzheimer's disease; PD; Parkinson's disease; AMPK; 5′ adenosine monophosphate-activated protein kinase; mTOR; mammalian target of rapamycin; HD; Huntington's disease; HH; hedera

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

Vitamin D receptor gene polymorphisms, smoking, and risk of sporadic Parkinson's disease in Japan

Keywords: بیماری پارکینسون; Case-control study; Gene-environment interaction; Japanese; Parkinson's disease; Smoking; VDR polymorphisms;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal

Keywords: بیماری پارکینسون; Parkinson's disease; Glucocerebrosidase; E326K; T369M; Synaptotagmin 11; GWAS;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Alteration in biochemical parameters in the brain of transgenic Drosophila melanogaster model of Parkinson's disease exposed to apigenin

Keywords: بیماری پارکینسون; apigenin; Drosophila melanogaster; oxidative stress; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice

Keywords: بیماری پارکینسون; Intracerebroventricular (i.c.v.) infusion; Olfactory dysfunction; Anxiety-like behavior; Olfactory bulb; Dopamine; Tyrosine hydroxylase; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Oligomeric α-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; GBA mutations; Enzymatic activity; Alpha-synuclein aggregation;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanistic evaluation of neuroprotective effect of estradiol on rotenone and 6-OHDA induced Parkinson's disease

Keywords: بیماری پارکینسون; Estradiol; Parkinson's disease; Rats; Histopathology; ROS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

CpG demethylation in the neurotoxicity of 1-methyl-4-phenylpyridinium might mediate transcriptional up-regulation of α-synuclein in SH-SY5Y cells

Keywords: بیماری پارکینسون; Parkinson's disease; α-synuclein; 6-hydroxydopamine; 1-methyl-4-phenylpyridinium; CpG demethylation;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model

Keywords: بیماری پارکینسون; 6-OHDA; 6-hydroxydopamine; AD; Alzheimer disease; BBB; blood-brain barrier; CL; contra-lateral; cpm; counts per min; DAPI; 4′-6-diamidino-2-phenylindole; FBS; fetal bovine serum certified; IL; ipsi-lateral; MEM; minimum essential media; nAChR; nicotin

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-κB signaling pathway

Keywords: بیماری پارکینسون; ANOVA; analysis of variance; DAT; dopamine transporter; HPLC; High Performance Liquid Chromatography; IL-1β; interleukin-1β; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MyD88; myeloid differentiation factor-88; NADPH; nicotinamide adenine dinucl

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Ellagic acid exerts protective effect in intrastriatal 6-hydroxydopamine rat model of Parkinson's disease: Possible involvement of ERβ/Nrf2/HO-1 signaling

Keywords: بیماری پارکینسون; 6-Hydroxydopamine; Apoptosis; Ellagic acid; Oxidative stress; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Paraquat; Lrrk; Minocycline; Lipid peroxidation; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Neurochemical effects of the R form of α-lipoic acid and its neuroprotective mechanism in cellular models of Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; R form α-lipoic acid; SH-SY5Y cells; Neurotoxin; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Pathological α-synuclein exacerbates the progression of Parkinson's disease through microglial activation

Keywords: بیماری پارکینسون; AKT; protein kinase B; AP-1; activator protein-1; BV-2; immortalized murine microglia cell line; CD11b; cluster of differentiation 11b; CD36; cluster of differentiation 36; CD44; cluster of differentiation 44; CD68; cluster of differentiation 68; CNS; cen

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Autophagy, its mechanisms and regulation: Implications in neurodegenerative diseases

Keywords: بیماری پارکینسون; Ageing; Parkinson's disease; Alzheimer's disease; Huntington's disease; Amyotrophic lateral sclerosis;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Behavioral phenotypes associated with MPTP induction of partial lesions in common marmosets (Callithrix jacchus)

Keywords: بیماری پارکینسون; Parkinson's disease; MPTP; Non-motor symptoms; Nonhuman primate model;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Role of estrogen and levodopa in 1-methyl-4-pheny-l-1, 2, 3, 6-tetrahydropyridine (mptp)-induced cognitive deficit in Parkinsonian ovariectomized mice model: A comparative study

Keywords: بیماری پارکینسون; Parkinson's disease; 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP); Levodopa; Acetylcholine esterase; Cognitive;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Changes of brain structure in Parkinson's disease patients with mild cognitive impairment analyzed via VBM technology

Keywords: بیماری پارکینسون; PD; Parkinson's disease; PD-MCI; Parkinson's disease with mild cognitive impairment; PD-NC; Parkinson's disease with normal cognition; PDD; Parkinson's disease with dementia; AD; Alzheimer's disease; MRI; magnetic resonance imaging; VBM; voxel-b

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation

Keywords: بیماری پارکینسون; DA neuron; dopaminergic neuron; DHE; dihydroethidium; DSP-4; N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride; Iba-1; ionized calcium binding adaptor molecule-1; iNOS; inducible nitric oxide synthase; LC/NE neuron; noradrenergic locus coeruleus

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats

Keywords: بیماری پارکینسون; 3-PBA; 3-phenoxybenzoic acid; BBB; blood-brain barrier; DNMTs; DNA methyltransferases; EDTA; ethylenediaminetetraacetic acid; LBD; Ligand Binding Domain; MSP; Methylation-Specific PCR; NOAEL; No Observed Adverse Effect Level; NuIP; Nurr1-interacting pro

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not

Keywords: بیماری پارکینسون; SN; substantia nigra; DA; dopamine; NA; noradrenaline; 5-HT; 5-hydroxytryptamine; LED; light emitting diode; PD; Parkinson's disease; TH; tyrosine hydroxylase; 5-HIAA; 5-hydroxyindoleacetic acid; DOPAC; 3, 4-dihydroxyphenylacetic acid; HVA; homovanillic

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry

Keywords: بیماری پارکینسون; AADC; aromatic L amino acid decarboxylase; COMT; catechol-O-methyl-transferase; CSF; cerebrospinal fluid; 6-OHDA; 6-hydroxydopamine; DBH; dopamine β-hydroxylase; DOPAC; 3,4-dihydroxyphenylacetic acid; 3-MT; 3-methoxytyramine; DA; dopamine; DAT; dopamine

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2017 سفارش ترجمه

Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability

Keywords: بیماری پارکینسون; OMM; outer mitochondrial membrane; DRP1; dynamin-related protein-1; MFN1; mitofusin 1; MFN2; mitofusin 2; mtDNA; mitochondrial DNA; PINK1; PTEN-induced putative kinase 1; PARK2; parkin; DOA; dominant optic atrophy; CMT2A; Charcot-Marie-Tooth neuropathy ty

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of PKCα and ERK1/2 signaling pathways in EGCG's protection against stress-induced neural injuries in Wistar rats

Keywords: بیماری پارکینسون; 5-HT; 5-hydroxytryptamine or serotonin; AD; Alzheimer's disease; ATP; adenosine triphosphate; BBB; blood-brain barrier; CNS; central nervous system; DA; dopamine; EGCG; epigallocatechin-3-gallate; ERK1/2; extracellular signal-regulated kinase 1/2; GC; g

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

VEGF mimic peptides: Potential applications in central nervous system therapeutics

Keywords: بیماری پارکینسون; AD; Alzheimer's disease; ALS; Amyotrophic lateral sclerosis; AMD; age-related macular degeneration; ARE; adenine/uridine rich elements; BBB; blood brain barrier; CNS; central nervous system; CSF; cerebrospinal fluid; ECS; electroconvulsive shock; HA; hy

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical development of a poly(2-oxazoline) (POZ) polymer therapeutic for the treatment of Parkinson's disease - Proof of concept of POZ as a versatile polymer platform for drug development in multiple therapeutic indications

Keywords: بیماری پارکینسون; Poly(2-oxazoline) or POZ; Poly(2-methyloxazoline) or PMOZ; Poly(2-ethyloxazoline) or PEOZ; Parkinson's disease; SER-214; Pharmacokinetics; Toxicology; Distribution; Immunogenicity; Preclinical; Clinical; Antibody-drug conjugates; Whole body autoradiogra

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

The translocator protein (18 kDa) and its role in neuropsychiatric disorders

Keywords: بیماری پارکینسون; 3α-HSD; 3α-hydroxysteroid dehydrogenase; 3β-HSD; 3β-hydroxysteroid dehydrogenase/Δ5−Δ4; AIF; apoptosis inducing factor; AD; Alzheimer's disease; ANT; adenine nucleotide translocator; AP-1; activator protein 1; APAF-1; apoptotic peptidase activat

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleAutosomal dominant Parkinson's disease: Incidence of mutations in LRRK2, SNCA, VPS35 and GBA genes in Brazil

Keywords: بیماری پارکینسون; Parkinson's disease; Autosomal dominant Parkinson's disease; LRRK2; SNCA; VPS35; GBA;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

An assessment of the frequency of mutations in the GBA and VPS35 genes in Hungarian patients with sporadic Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; GBA mutations; L444P; VPS35 mutation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease

Keywords: بیماری پارکینسون; PD; Parkinson's disease; AD; Alzheimer's disease; TREM2; the triggering receptor expressed on myeloid cells 2 gene; VPS35; the vacuolar protein sorting 35 gene; EIF4G1; the eukaryotic translation initiation factor 4-gamma 1 gene; S100B; the S100 calci

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperThe GBA, DYRK1A and MS4A6A polymorphisms influence the age at onset of Chinese Parkinson patients

Keywords: بیماری پارکینسون; Parkinson's disease; Alzheimer's disease; Age at onset;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Vitamin D receptor gene rs4334089 polymorphism and Parkinson's disease in Iranian population

Keywords: بیماری پارکینسون; Parkinson's disease; VDR; rs4334089; Iranian population;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

No association of GPNMB rs156429 polymorphism with Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy in Chinese population

Keywords: بیماری پارکینسون; Parkinson's disease; Amyotrophic lateral sclerosis; Multiple system atrophy; GPNMB; rs156429 polymorphism;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleAssociation of DYRK1A polymorphisms with sporadic Parkinson's disease in Chinese Han population

Keywords: بیماری پارکینسون; PD; Parkinson's disease; Dyrk1A; dual-specificity tyrosine phosphorylation-regulated kinase 1A; SNPs; single nucleotide polymorphism; DA; dopamine; LBs; Lewy bodies; AD; Alzheimer's disease; HC; health control; NMS; none motor syndrome; UPDRS III; Uni

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature

Keywords: بیماری پارکینسون; Parkinson's disease; CHCHD2; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy

Keywords: بیماری پارکینسون; mGlu4; Metabotropic glutamate receptor; Positive allosteric modulator (PAM); Parkinson's disease; Structure-activity relationship (SAR);

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Pinocembrin attenuates MPP+-induced neurotoxicity by the induction of heme oxygenase-1 through ERK1/2 pathway

Keywords: بیماری پارکینسون; Parkinson's disease; Pinocembrin; MPP+; Heme oxygenase-1; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Activated caspase-9 immunoreactivity in glial and neuronal cytoplasmic inclusions in multiple system atrophy

Keywords: بیماری پارکینسون; DLB; dementia with Lewy bodies; GCI; glial cytoplasmic inclusion; MSA; multiple system atrophy; MSA-C; MSA of the cerebellar type; MSA-P; MSA of the parkinsonian type; NCI; neuronal cytoplasmic inclusion; PBS; phosphate-buffered saline; PD; Parkinson's

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Folded concave penalized learning in identifying multimodal MRI marker for Parkinson's disease

Keywords: بیماری پارکینسون; Parkinson's disease; Biomarker discovery; Penalized learning; Magnetic resonance imaging; Diffusion tensor imaging; R2*;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportStatin use and risk of Parkinson's disease: A meta-analysis

Keywords: بیماری پارکینسون; Statin; Parkinson's disease; Meta-analysis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه