Keywords: پتنولید; Asthma; Lung histology; Murine model; Parthenolide; Tanacetum Parthenium;
مقالات ISI پتنولید (ترجمه نشده)
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Synthesis of dual-action parthenolide prodrugs as potent anticancer agents
Keywords: پتنولید; Parthenolide; Cytarabine; Melphalan; aza-Michael addition; Cytotoxic activity;
Keywords: پتنولید; Parthenolide; Experimental autoimmune neuritis; Cytokines; Lymphocyte proliferation; Apoptosis; PAR; parthenolide; EAN; experimental autoimmune neuritis; GBS; Guillain-Barré syndrome; EAE; experimental autoimmune encephalomyelitis; BPM; bovine peripher
Keywords: پتنولید; Parthenolide; Active functional groups; Structural rearrangement; Parthenolide derivatives; Anticancer activity;
Keywords: پتنولید; Parthenolide; Total synthesis; Anticancer activity; Analogue;
Keywords: پتنولید; Parthenolide; Biosynthetic pathway reconstitution; Feverfew; Metabolic engineering
Keywords: پتنولید; 5-Fluorouracil; Parthenolide; Combination therapy; Anti-cancer; Colorectal cancer;
Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis
Keywords: پتنولید; PTL; parthenolide; AML; acute myelogenous leukemia; CSCs; cancer stem cells; DMAPT; dimethylamino-parthenolide; PTDH; phosphite dehydrogenase; NADPH; nicotinamide adenine dinucleotide phosphate (reduced); IPTG; β-d-1-thiogalactopyranoside; δ-ALA; δ-ami
Exploring the impact of parthenolide as anti-quorum sensing and anti-biofilm agent against Pseudomonas aeruginosa
Keywords: پتنولید; Parthenolide; Quorum sensing; Gene expression; Molecular docking; P. aeruginosa; Autoinducer synthase;
Parthenolide reduces metastasis by inhibition of vimentin expression and induces apoptosis by suppression elongation factor αâ¯ââ¯1 expression
Keywords: پتنولید; Parthenolide; Metastasis; Apoptosis; Vimentin and Elongation factor αâ¯ââ¯1; PTL; Parthenolide; SEM; Scanning Electron Microscopy;
Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression
Keywords: پتنولید; Parthenolide; Temozolomide; Glioma; NF-κB; MGMT;
Copper(I) oxide nanoparticles catalyzed click chemistry based synthesis of melampomagnolide B-triazole conjugates and their anti-cancer activities
Keywords: پتنولید; Melampomagnolide B; Parthenolide; Click chemistry; Copper(I) oxide nanoparticles; Anti-cancer activity;
Osteopontin plays a unique role in resistance of CD34 +/CD123 + human leukemia cell lines KG1a to parthenolide
Keywords: پتنولید; AML; Parthenolide; Osteopontin; KG1a cell line;
Synthesis and anti-acute myeloid leukemia activity of C-14 modified parthenolide derivatives
Keywords: پتنولید; Parthenolide; Acute myeloid leukemia; Apoptosis; KG1a; Synthesis;
Original ArticlePharmacological evidence for the bone-autonomous contribution of the NFκB/β-catenin axis to breast cancer related osteolysis
Keywords: پتنولید; NFκB; β-Catenin; Breast cancer; Osteolysis; Bone; PTN; Parthenolide; NFκB; nuclear factor kappa-B; RANK; receptor activator of NFκB; RANKL; RANK ligand; TNFα; tumour necrosis factor alpha; IL1β; interleukin 1 beta; CD40L; Cluster of differentiation
Succinamide derivatives of melampomagnolide B and their anti-cancer activities
Keywords: پتنولید; Parthenolide; Melampomagnolide B; Anti-cancer activity; Succinamide derivatives; IKKβ inhibition;
Determination of parthenolide in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study
Keywords: پتنولید; Parthenolide; UPLC-MS/MS; Rat plasma; Pharmacokinetics
Parthenolide ameliorates Concanavalin A-induced acute hepatitis in mice and modulates the macrophages to an anti-inflammatory state
Keywords: پتنولید; Parthenolide; Acute hepatitis; Macrophage; STAT3;
Stereoselective total synthesis of (±)-parthenolide and (±)-7-epi-parthenolide
Keywords: پتنولید; Parthenolide; Substrate-controlled; Stereoselective; Stereoisomers;
Magnesium and manganese interactively modulate parthenolide accumulation and the antioxidant defense system in the leaves of Tanacetum parthenium
Keywords: پتنولید; Antioxidant enzymes; Feverfew; Magnesium; Manganese; Parthenolide
LC-MS quantification of parthenolide and cholinesterase inhibitory potential of selected Tanacetum L. (Emend. Briq.) taxa
Keywords: پتنولید; Tanacetum; Parthenolide; Acetylcholinesterase; Butyrylcholinesterase; Alzheimer's disease;
Parthenolide induces autophagy via the depletion of 4E-BP1
Keywords: پتنولید; PTL; parthenolide; eIF4E; eukaryotic initiation factor 4E; 4E-BP1; translation initiation factor eIF4E binding protein 1; AML; acute myeloid leukemia; ER; endoplasmic reticulum; ROS; reactive oxygen species; mTOR; mammalian target of rapamycin; MEF; mouse
Repressed Ca2+ clearance in parthenolide-treated murine brain bEND.3 endothelial cells
Keywords: پتنولید; Parthenolide; Endothelial cells; Ca2+ clearance; Ca2+ pump; Endoplasmic reticulum stress
Widespread pain reliever profile of a flower extract of Tanacetum parthenium
Keywords: پتنولید; Feverfew; Pain; Osteoarthritis; Neuropathic pain; Chemotherapy-induced neuropathy; Parthenolide
Induction of apoptosis by parthenolide in human oral cancer cell lines and tumor xenografts
Keywords: پتنولید; Parthenolide; Apoptosis; Bim; Death receptor 5; Oral cancer;
Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues
Keywords: پتنولید; PTL; parthenolide; LSC; leukemic stem cell; AML; acute myeloid leukemia; SL; sesquiterpene lactone; HSC; hematopoietic stem cell; DMAPT; dimethylamino-parthenolide; MelB; melampomagnolide B; ROS; reactive oxygen species; PtO2; platinum(IV) oxide; DME; dim
Therapeutic effect of Cryptotanshinone on collagen-induced arthritis in rats via inhibiting nuclear factor kappa B signaling pathway
Keywords: پتنولید; BMM; bone marrow macrophage; CIA; collagen-induced arthritis; CTS; Cryptotanshinone; FLS; fibroblast-like synoviocytes; Lef; leflunomide; M-CSF; macrophage colony-stimulating factor; MMP; matrix metalloproteinase; PAR; parthenolide; RA; rheumatoid arthr
Anti-cancer activity of carbamate derivatives of melampomagnolide B
Keywords: پتنولید; Parthenolide; Melampomagnolide B; Anti-cancer activity; Carbamates; Heterocyclic amines;
Parthenolide inhibits polyethylene particle-induced mouse calvarial osteolysis in vivo
Keywords: پتنولید; Polyethylene particle; Parthenolide; Micro-CT; Osteolysis; Calvarium;
Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
Keywords: پتنولید; Parthenolide; Melampomagnolide B; Heck reaction; Oocyte maturation; Anti-cancer activity
St. John's Wort seed and feverfew flower extracts relieve painful diabetic neuropathy in a rat model of diabetes
Keywords: پتنولید; St. John's Wort; Feverfew; Painful diabetic neuropathy; Hypericin; Hyperforin; Parthenolide
Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities
Keywords: پتنولید; Pancreatic cancer; Parthenolide; Amination; Michael addition; α-Methylene-γ-butyrolactones;
Potent anti-inflammatory activity of sesquiterpene lactones from Neurolaena lobata (L.) R. Br. ex Cass., a Q'eqchi' Maya traditional medicine
Keywords: پتنولید; Neurolaena lobata; Asteraceae; Sesquiterpene lactones; Neurolenin; Lobatin; Parthenolide; Anti-inflammatory; TNF-α; Traditional medicine;
Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel
Keywords: پتنولید; CGRP; Migraine; Parthenolide; TRPA1;
Parthenolide reduces cell proliferation and prostaglandin estradiol synthesis in human endometriotic stromal cells and inhibits development of endometriosis in the murine model
Keywords: پتنولید; Parthenolide; NF-κB pathway; cell proliferation; COX-2-PGE2;
Parthenolide from Parthenium integrifolium reduces tumor burden and alleviate cachexia symptoms in the murine CT-26 model of colorectal carcinoma
Keywords: پتنولید; Cancer cachexia; Parthenolide; Parthenium integrifolium; Tumor burden; Skeletal muscle
Genetical, developmental and spatial factors influencing parthenolide and its precursor costunolide in feverfew (Tanacetum parthenium L. Schulz Bip.)
Keywords: پتنولید; MVA, mevalonic acid; UPLC, ultra performance liquid chromatography; MS, mass spectrometry; MRM, multiple reaction monitoring; PDA, photo diode array; RT, retention time; IS, internal standardTanacetum parthenium; Medicinal plant; Parthenolide; Costunolide
Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation
Keywords: پتنولید; Parthenolide; Doxorubicin resistance; P-glycoprotein; NF-κB; HSP70
How close are we to targeting the leukemia stem cell?
Keywords: پتنولید; acute myeloid leukemia; AML; glutathione; leukemic stem cell; parthenolide; piperlongumine
Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates dextran sulfate sodium-induced colitis in mice
Keywords: پتنولید; Nuclear factor (NF)-κB; Parthenolide; Ulcerative colitis; Dextran sulfate sodium-induced colitis
Feverfew as a source of bioactives for functional foods: Storage stability in model beverages
Keywords: پتنولید; Feverfew infusions; Parthenolide; Colour; Stability; Beverages
Parthenolide inhibits STAT3 signaling and attenuates angiotensin II-induced left ventricular hypertrophy via modulation of fibroblast activity
Keywords: پتنولید; Pressure overload; Left ventricular hypertrophy; STAT3; Parthenolide; Fibrosis
Biosynthesis and localization of parthenolide in glandular trichomes of feverfew (Tanacetum parthenium L. Schulz Bip.)
Keywords: پتنولید; FDP; farnesyl diphosphate; MVA; mevalonic acid; GAS; germacrene A synthase; Tp; Tanacetum parthenium; CarS; caryophyllene synthase; RACE; rapid amplification of cDNA ends; RGE; relative gene expression; ADS; amorpha-4,11-diene synthase; SEM; scanning elec
Synergistic effects of parthenolide and benznidazole on Trypanosoma cruzi
Keywords: پتنولید; Tanacetum vulgare; Parthenolide; Trypanosoma cruzi; Trypanocidal activity; Synergism
Tailored α-methylene-γ-butyrolactones and their effects on growth suppression in pancreatic carcinoma cells
Keywords: پتنولید; Pancreatic cancer; Anti-proliferation; Alpha-methylene-gamma-butyrolactones; Allylboration; Parthenolide
Independent component analysis: Mining microarray data for fundamental human gene expression modules
Keywords: پتنولید; Microarrays; Independent component analysis; Data mining; Parthenolide; Gene modules
Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-κB inhibitor, DMAPT (LC-1)
Keywords: پتنولید; Sesquiterpene lactone; Parthenolide; Aminoparthenolide analogs; NF-κB inhibitor; DMAPT (LC-1); Anti-leukemic activity; Leukemia;
Effects of extraction temperature on the phenolic and parthenolide contents, and colour of aqueous feverfew (Tanacetum parthenium) extracts
Keywords: پتنولید; Feverfew; Tanacetum parthenium; Total phenols; Parthenolide; Colour
New agents for AML and MDS
Keywords: پتنولید; acute myeloid leukaemia (AML); myelodysplastic syndromes (MDS); FMS-like tyrosine kinase receptors (FLT3 inhibitors); farnesyl transferase inhibitor (FTI); clofarabine; histone deacetylase (HDAC); DNMT; mTOR; parthenolide; PIM kinase;
Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones
Keywords: پتنولید; Planaria; Cocaine; Parthenolide; Costunolide; Santonin; β-Eudesmol