Keywords: آگونیست جزئی; Receptor theory; Partial agonist; Mixture toxicology; Synergism; Isoboles; Isobolographic analysis;
مقالات ISI آگونیست جزئی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: آگونیست جزئی; AF-1; activation function-1; AF-2; activation function-2; AP-1; activator protein 1; dppp; 1,3-bis(diphenylphosphino)propane; DEX; dexamethasone; DIEA; N,N-diisopropylethylamine; FKBP5; FK506-binding protein 5; GR; glucocorticoid receptor; GRE; glucocorti
Keywords: آگونیست جزئی; Aripiprazole; Partial agonist; Switching; Super sensitivity; Discontinuation; Worsening; Predictor;
Keywords: آگونیست جزئی; Melatonin; MT1; MT2; Naphthofuranic derivatives; Partial agonist
Keywords: آگونیست جزئی; Partial agonist; Addiction; Dopamine; Antipsychotics; Reward
Keywords: آگونیست جزئی; Estrogen receptor; Partial agonist; SERM; Carborane
Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings
Keywords: آگونیست جزئی; BRET; bioluminescence resonance energy transfer; cAMP; cyclic adenosine monophosphate; Dmt; 2,6-dimethyltyrosine; DOP; δ-opioid receptor; EC50; half maximal effective concentration; EPAC; exchange protein directly activated by cAMP; GPI; guinea pig ileum
Receptor partial agonism and method to express receptor partial activation with respect to novel Full Logistic Model of mixture toxicology
Keywords: آگونیست جزئی; Receptor theory; Partial agonist; Mixture toxicology; Equilibrium dissociation constant; Efficacy; Drug potency;
Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor
Keywords: آگونیست جزئی; β-ABA; β-aminobutyric acid; β-AIBA; β-aminoisobutyric acid; GlyR; glycine receptor; LBD; ligand-binding domain; MBS; Modified Barth's Saline; Popen; probability of channel being open; SEM; standard error of the mean; Ï; dwell-time; TM; transmembran
Dopamine serotonin stabilizer RP5063: A randomized, double-blind, placebo-controlled multicenter trial of safety and efficacy in exacerbation of schizophrenia or schizoaffective disorder
Keywords: آگونیست جزئی; RP5063; Safety; Efficacy; Schizophrenia; Schizoaffective; Trial; Partial agonist; Stabilizer;
Effects of BMS-902483, an α7 nicotinic acetylcholine receptor partial agonist, on cognition and sensory gating in relation to receptor occupancy in rodents
Keywords: آگونیست جزئی; Nicotinic; Partial agonist; Behavior; LTP; Target engagement; Ex vivo;
Structural determinants of diphenethylamines for interaction with the κ opioid receptor: Synthesis, pharmacology and molecular modeling studies
Keywords: آگونیست جزئی; κ opioid receptor; Diphenethylamine; Agonist; Antagonist; Partial agonist; SAR; Molecular dynamics;
Synthesis and biological evaluation of novel m-carborane-containing estrogen receptor partial agonists as SERM candidates
Keywords: آگونیست جزئی; Carborane; Estrogen receptor; Partial agonist; SERM;
Discovery of dihydroquinazolinone derivatives as potent, selective, and CNS-penetrant M1 and M4 muscarinic acetylcholine receptors agonists
Keywords: آگونیست جزئی; Muscarinic acetylcholine receptors; M1 muscarinic acetylcholine receptor; M4 muscarinic acetylcholine receptor; Partial agonist; Antipsychotic agent; Dihydroquinazolinone derivatives;
Peroxisome proliferator-activated receptor gamma (PPARγ) has multiple binding points that accommodate ligands in various conformations: Structurally similar PPARγ partial agonists bind to PPARγ LBD in different conformations
Keywords: آگونیست جزئی; Peroxisome proliferator-activated receptor; PPAR; X-ray; Partial agonist
Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXRβ
Keywords: آگونیست جزئی; SWBBNSPWRVCYAE-UHFFFAOYSA-N; WZMZHHPXANSLBG-UHFFFAOYSA-N; KMTFPMRUPSWRTQ-UHFFFAOYSA-N; DIRKHQVAVLSYMA-UHFFFAOYSA-N; XQWURCYLMCTAFE-UHFFFAOYSA-N; STNGIHCHDLCYEV-UHFFFAOYSA-N; VOOZJAGZCXOELE-UHFFFAOYSA-N; ZXTOKWKHXXGVMT-UHFFFAOYSA-N; SALZQMSOIKCKNM-UHFFFAOY
Neuropharmacology and analgesiaThe antipsychotic aripiprazole induces antinociceptive effects: Possible role of peripheral dopamine D2 and serotonin 5-HT1A receptors
Keywords: آگونیست جزئی; Partial agonist; Nociception; Analgesia; Dopamine; Serotonin;
Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity
Keywords: آگونیست جزئی; VDR; vitamin D receptor; LBD; ligand-binding domain; 1α,25-(OH)2D3; 1α,25-dihydroxyvitamin D3; SERM; selective estrogen receptor modulator; ERα; estrogen receptor α; PPARγ; peroxisome proliferator-activated receptor γ; Vitamin D; Nuclear receptor; X
Pyrrolo- and pyridomorphinans: Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists
Keywords: آگونیست جزئی; TWHOEFFOOYPJNA-JHIHRYPMSA-N; FZPQMESFNIKSCV-GTNJNHEQSA-NOpioid; Antagonist; Non-selective; Naltrexone; Partial agonist
SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C
Keywords: آگونیست جزئی; SKF-83959; Dopamine D1 receptor; Dopamine D5 receptor; Phospholipase C; Adenylate cyclase; Partial agonist; Functional selectivity; Ligand bias; Rat striatum;
Identification of a novel partial agonist of liver X receptor α (LXRα) via screening
Keywords: آگونیست جزئی; ABC; ATP-binding cassette; ApoE; apolipoprotein E; DRIP205; vitamin D receptor-interacting protein 205; FAS; fatty acid synthase; GAPDH; glyceraldehyde-phosphate dehydrogenase; HDL; high-density lipoprotein; LBD; ligand-binding domain; LXR; liver X recept
Identification of oligomer proanthocyanidins (F2) isolated from grape seeds as a formyl peptide receptor 1 partial agonist
Keywords: آگونیست جزئی; Proanthocyanidins; F2; Formyl peptide receptor; Ligand; Partial agonist;
ReviewDopamine D3 receptor as a new pharmacological target for the treatment of depression
Keywords: آگونیست جزئی; Depression; Dopamine D3 receptor; Brain-derived neurotrophic factor; Partial agonist; Treatment-resistant depression; Aripiprazole;
The carbonate analogues of 5â²-halogenated resiniferatoxin as TRPV1 ligands
Keywords: آگونیست جزئی; TRPV1 agonist; TRPV1 antagonist; Partial agonist; Halogenation; Resiniferatoxin; Molecular modelling;
Design and synthesis of a series of α-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility
Keywords: آگونیست جزئی; NR, nuclear receptor; hPPAR, human peroxisome proliferator-activated receptor; LBD, ligand-binding domain; PDB, protein data bank3VSO; hPPARγ LBD-(R)-7JHuman peroxisome proliferator-activated receptor; PPAR gamma; Partial agonist; Structural biology
Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues
Keywords: آگونیست جزئی; Kappa opioid receptor; Partial agonist; Mood; Anxiety; Drug addiction; Salvinorin;
The Monoamine Stabilizer (-)-OSU6162 Attenuates Voluntary Ethanol Intake and Ethanol-Induced Dopamine Output in Nucleus Accumbens
Keywords: آگونیست جزئی; Alcohol; dependence; dopamine stabilizer; drug development; microdialysis; partial agonist;
Positive allosteric modulation of α4β2 nAChR agonist induced behaviour
Keywords: آگونیست جزئی; 6-OHDA model; Acute pain; Striatal dopamine release; α4β2 nAChR; Partial agonist; Positive allosteric modulation
High-throughput screening with a miniaturized radioligand competition assay identifies new modulators of human α2-adrenoceptors
Keywords: آگونیست جزئی; α2-Adrenoceptors; Lysergol; 2″,2‴′-Bisepigallocatechin digallate2″,2‴′-Bisepigallocatechin digallate; Partial agonist; GPCR; Chemical libraries
EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
Keywords: آگونیست جزئی; α7 nAChR; Object recognition task; Memory; Partial agonist; Novel mechanism of action; Acetylcholine esterase inhibitor
Receptor activity and conformational analysis of 5â²-halogenated resiniferatoxin analogs as TRPV1 ligands
Keywords: آگونیست جزئی; TRPV1 agonist; TRPV1 antagonist; Partial agonist; Halogenation; Resiniferatoxin; Molecular modeling;
Conformationally constrained analogs of BAY 59–3074 as novel cannabinoid receptor ligands
Keywords: آگونیست جزئی; Partial agonist; Cannabinoid; CB2 selective
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist
Keywords: آگونیست جزئی; Melanocortin subtype-4 receptor; MC4R; Partial agonist; Urea piperazine; Erectile dysfunction; Obesity
Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy
Keywords: آگونیست جزئی; PPARd; Partial agonist
In vitro pharmacology of aripiprazole, its metabolite and experimental dopamine partial agonists at human dopamine D2 and D3 receptors
Keywords: آگونیست جزئی; Aripiprazole; Psychosis; Antipsychotic; Dopamine D2 receptor; Dopamine D3 receptor; Partial agonist
Improving the developability profile of pyrrolidine progesterone receptor partial agonists
Keywords: آگونیست جزئی; Pyrrolidine; Progesterone; Progesterone receptor; Partial agonist; hERG; Rat DMPK; Rat OVX model; Endometriosis
Development and application of an LC-MS/MS method for measuring the effect of (partial) agonists on cAMP accumulation in vitro
Keywords: آگونیست جزئی; cAMP; ATP; LC-MS; Partial agonist; HILIC; Dopamine D2;
The partial dopamine agonist pardoprunox (SLV308) administered in combination with l-dopa improves efficacy and decreases dyskinesia in MPTP treated common marmosets
Keywords: آگونیست جزئی; Pardoprunox (SLV308); Partial agonist; l-dopa; Dyskinesia; MPTP; Common marmoset
l-Stepholidine reduced l-DOPA-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease
Keywords: آگونیست جزئی; l-Stepholidine; Parkinson's disease; Dyskinesia; 5-HT1A receptor; Partial agonist;
The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: A review
Keywords: آگونیست جزئی; Varenicline; Alpha4 beta2 nicotinic acetylcholine receptor; Partial agonist; Addiction; Drug dependence; Relapse prevention
The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay
Keywords: آگونیست جزئی; Neurotensin; Partial agonist; Antagonist; Nonpeptide
Potent and selective α1A adrenoceptor partial agonists—Novel imidazole frameworks
Keywords: آگونیست جزئی; Partial agonist; α1A Adrenergic receptor
Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists
Keywords: آگونیست جزئی; Progesterone receptor; Agonist; Partial agonist; Endometriosis; Nuclear receptor; Hormone receptors
Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
Keywords: آگونیست جزئی; Progesterone; Partial agonist; Full agonist; Triazole; Tetrazole;
6,7-Dihydro-5H-pyrrolo[1,2-a] imidazoles as potent and selective α1A adrenoceptor partial agonists
Keywords: آگونیست جزئی; Alpha1a adrenoceptor; Partial agonist; Pyrroloimidazole; CNS penetration; Selectivity
Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists
Keywords: آگونیست جزئی; Progesterone receptor; Agonist; Partial agonist; Endometriosis; Nuclear receptors; Hormone receptors; hERG binding; Androgen receptor; OVX rat model; Progestin
Receptor reserve-dependent properties of antipsychotics at human dopamine D2 receptors
Keywords: آگونیست جزئی; Aripiprazole; Schizophrenia; Antipsychotic; Dopamine D2 receptor; Partial agonist; Receptor reserve
Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance
Keywords: آگونیست جزئی; Partial agonist; Heterodimer; Gambling; Adenylyl cyclase supersensitivity; Allosteric; Dopamine D1 and D3 receptors
FGF21 N- and C-termini play different roles in receptor interaction and activation
Keywords: آگونیست جزئی; FGF; fibroblast growth factor; ERK; extracellular signal-regulated kinase; HSPG; heparin sulfate proteoglycan; Fibroblast growth factor-21; β-Klotho; Fibroblast growth factor receptor; Partial agonist;
Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats
Keywords: آگونیست جزئی; Nicotine; Varenicline; Cytisine; Drug discrimination; α4β2 nicotinic acetlycholine receptor; Partial agonist