دانلود مقالات ISI درباره Pbk + ترجمه فارسی

مقایسه میزان هگزافلورید سولفور 20٪ در برابر تامپوناد هوا در کراتوپلاستی اندوتلیال غشای دسامبر

Comparison of Sulfur Hexafluoride 20% versus Air Tamponade in Descemet Membrane Endothelial Keratoplasty

Keywords: CDVA; corrected distance visual acuity; cECC; central endothelial cell count; D; diopter; DMEK; Descemet membrane endothelial keratoplasty; EDM; endothelium-Descemet membrane; IOP; intraocular pressure; logMAR; logarithm of the minimum angle of resoluti

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

کراتوپلاستی در ایالات متحده

Keratoplasty in the United States

Keywords: ABK; aphakic bullous keratopathy; ALK; anterior lamellar keratoplasty; DALK; deep anterior lamellar keratoplasty; DMEK; Descemet membrane endothelial keratoplasty; DSAEK; Descemet stripping automated endothelial keratoplasty; DSEK; Descemet stripping endo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat

Keywords: Physiologically based kinetic (PBK) model; Lasiocarpine; Riddelliine; Liver toxicity; In vitro-in vivo extrapolation; Reverse dosimetry; BMDL5-BMDU5; lower/upper limit of the 90% confidence interval of the benchmark dose that gives a 5% response; BMDL10;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment

Keywords: 3Rs; Reduction, Replacement, Refinement; PBPK; physiologically based pharmacokinetic; 2D; two-dimensional; 3D; three-dimensional; HTS; high-throughput screening; IVIVE; in vitro-in vivo extrapolation; ADME; absorption, distribution, metabolism and excreti

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Natural occurrence of genotoxic and carcinogenic alkenylbenzenes in Indonesian jamu and evaluation of consumer risks

Keywords: Alkenylbenzenes; Jamu; Margin of exposure (MOE); Risk assessment; BMDL10; lower confidence limit of the benchmark dose resulting in a 10% extra cancer incidence; EDI; Estimated daily intake; EFSA; European Food Safety Authority; ILSI; International Life S

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

On p53 revival using system oriented drug dosage design

Keywords: p53; Mdm2; Cancer; Nutlin; PBK;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling

Keywords: VCBA; PBK; PBD; Estragole; DNA adduct; Risk assessment; KNIME workflow;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data - A case study with caffeine

Keywords: AUC; area under the curve; BMDL; benchmark dose lower confidence interval; Cmax; maximum concentration; HLV; human limit value; MOE; margin of exposure (synonymous to MOS); MOIE; margin of internal exposure; MOS; margin of safety; NOAEL; no observed adver

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Mode of action based risk assessment of the botanical food-borne alkenylbenzene apiol from parsley using physiologically based kinetic (PBK) modelling and read-across from safrole

Keywords: Apiol; Safrole; PBK modelling; Read-across; Risk assessment; Margin of exposure; ADD; 4-allyl-3,6-dimethoxybenzene-1,2-diol; BMDL10; the lower confidence limit of the benchmark dose resulting in a 10% extra cancer; DHA; 2′,3′-di hydroxyapiol; DMSO; di

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I

Keywords: Physiologically based kinetic (PBK) model; Aristolochic acid I (AAI); Kidney toxicity; In vitro-in vivo extrapolation; Risk assessment; Physiologically based pharmacokinetic (PBPK) model; AA; aristolochic acid; AAI; aristolochic acid I; AAII; aristoloch

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2016 سفارش ترجمه

Use of physiologically based kinetic (PBK) modeling to study interindividual human variation and species differences in plasma concentrations of quercetin and its metabolites

Keywords: PBK; physiologically based kinetic; AUC; area under the curve; ADME; absorption, distribution, metabolism, excretion; Q4′Gly; quercetin-4′-O-glucoside; Q34′diGly; quercetin-3,4′-O-diglucoside; DMSO; dimethyl sulfoxide; Quercetin; Absorption distri

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety

Keywords: AR; adenosine receptor; cAMP; 3′-5′-cyclic adenosine monophosphate; CSC; 8-(3-chlorostyryl)caffeine; IL; interleukin; ICV; intracerebroventricular; IP; intraperitoneal; KATP channels; ATP-sensitive potassium channels; KO; knockout; PBS; phosphate buff

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling

Keywords: Methyleugenol; PBK; Nevadensin; Inhibition; Bioactivation; In vivo; NTP; National Toxicology Program; SCF; Scientific Committee on Food; FEMA; Flavor and Extract Manufacturers Association; PBK; physiologically based kinetic; NEV; nevadensin; DMSO; dimethy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

c-Myc and E2F1 drive PBK/TOPK expression in high-grade malignant lymphomas

Keywords: PBK; TOPK; PDZ-binding kinase; c-Myc; E2F1; Burkitts lymphoma; NHL; Non-Hodgkins lymphoma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse

Keywords: ko; knockout; KOMDIP; KnockOut Mouse Data Inventory of cholesterol Phenotype; LDL; low density lipoprotein; HDL; high density lipoprotein; C; cholesterol; CE; cholesteryl ester; FC; free cholesterol; TC; total plasma cholesterol; PBK; physiologically base

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه