دانلود مقالات ISI درباره Pec50 + ترجمه فارسی

شناسایی بقایای تثبیت شده حفظ شده برای فعالیت زیستی یک پپتید پدال / نوروپپتید نوع ارکوکینین

Identification of evolutionarily conserved residues required for the bioactivity of a pedal peptide/orcokinin-type neuropeptide

Keywords: SMP; starfish myorelaxant peptide; SAR; structure-activity relationships; PP; pedal peptide; OK; orcokinin; ACh; acetylcholine; TFA; trifluoroacetic acid; RP; reversed-phase; HOBT; 1-hydroxybenzotriazole; DIPCI; N,N-diisopropylcarbodimide; ASW; artificial

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

مطالعه تطبیقی ​​کلاهک های طراحی مهارکننده های پروتئاز سیتی

A comparative study of warheads for design of cysteine protease inhibitors

Keywords: Boc; tert-butyloxycarbonyl; Cbz; carboxybenzyl; CC50; half maximal cytoxicity concentration; EC50; half maximal effective concentration; EDC; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; IBX; 2-iodoxybenzoic acid; Ki; inhibitory constan

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

هیستیدین 37.36 (305) در دامنه فعال سازی گیرنده پپتید محافظت شده از گونادوتروپین هورمون آزاد کننده گیرنده های گیرنده اتصال پپتید و فعال شدن گیرنده

Histidine7.36(305) in the conserved peptide receptor activation domain of the gonadotropin releasing hormone receptor couples peptide binding and receptor activation

Keywords: 2-Nal; 2-naphthylalanine; B0; radio-ligand bound in the absence of competing unlabeled ligand; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; GnRH; gonadotropin releasing hormone; GPCR; G protein-coupled receptor; IP; inositol phosphate;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

تعیین فارماکولوژی تعامل بین آکلییدینیم برمید و فومورات فرموترول بر روی برونکسی جدا شده از انسان

Pharmacological characterization of the interaction between aclidinium bromide and formoterol fumarate on human isolated bronchi

Keywords: β2-AR; β2-adrenoreceptor; ASM; airway smooth muscle; BI; Bliss independence; COPD; chronic obstructive pulmonary disease; CRC; concentration-response curve; E; effect; EFS; electrical field stimulation; ECn; effective concentration for n% of maximal eff

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Is selective 5-HT1F receptor agonism an entity apart from that of the triptans in antimigraine therapy?

Keywords: 5-HT; 5-hydroxytryptamine; BBB; blood brain barrier; CGRP; calcitonin gene-related peptide; DHSC; dorsal horn of the spinal cord; logDpH7.4; distribution coefficient at physiological pH; MMA; middle meningeal artery; ND; not defined; NTS; nucleus tractus

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells

Keywords: AC; adenylyl cyclase; 2-APB; 2-aminoethoxyphenylborane; ASM; airway smooth muscle; cAMP; 3',5'-cyclic AMP; COPD; chronic obstructive pulmonary disease; [Ca2+]i; intracellular free Ca2+ concentration; DMSO; dimethyl sulfoxide; EC50 (IC50); half-maximally e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand-modulated calcium signaling

Keywords: CHO-hPAR2; Chinese hamster ovary cells transfected with human PAR2; EC50; molar concentration that produces 50% of the maximum response of an agonist; ECL2; extracellular loop 2; Fluo-3; {[2-(2-{2-[Bis(carboxymethyl)amino]-5-(2,7-dichloro-6-hydroxy-3-oxo-

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Contrasting cardiovascular properties of the µ-opioid agonists morphine and methadone in the rat

Keywords: ECG; electrocardiogram; HR; heart rate; KPSS; isotonic potassium physiological salt solution; MAP; mean arterial pressure; NO; nitric oxide; NOS; nitric oxide synthase; pEC50; the negative log10 of agonist concentration that caused 50% of the maximum resp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Extracellular NAADP affords cardioprotection against ischemia and reperfusion injury and involves the P2Y11-like receptor

Keywords: I/R; ischemia/reperfusion; LVEDP; left ventricular end-diastolic pressure (mm Hg); NAADP; nicotinic acid adenine dinucleotide phosphate; pEC50; negative logarithm to base 10 of the half maximal effective concentration; RPP; rate-pressure product (mm Hg be

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method

Keywords: DMEM medium; Dulbecco's Minimal Essential Medium; EC50; concentration necessary to elicit 50% of the maximal effect; ECL; extracellular loops (ECL1 between TM2-3, ECL2 between TM4-5 and ECL3 between TM6-7); HEK; Human Embryonic Kidney (HEK) 293T cel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor

Keywords: CGRP; calcitonin gene-related peptide; CLR; calcitonin receptor-like receptor; ECD; extracellular domain; GPCR; G-protein coupled receptor; HA; hemagglutinin; pEC50; -log(EC50); PBS; phosphate buffered saline; RAMP; receptor activity modifying protein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Impaired Bladder Function in Aging Male Rats

Keywords: urinary bladder; physiology; aging; urodynamics; male; BC; bladder capacity; Bcom; bladder compliance; BP; baseline pressure; CRC; carbachol response curve; EC50; drug concentration needed to produce 50% of calculated maximum; EFS; electrical field stimul

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه