Keywords: گیرنده بنزودیازپین محیطی; ANT; adenine nucleotide translocase; [Ca2+]c; cytosolic calcium concentration; [Ca2+]m; mitochondrial calcium concentration; CsA; cyclosporine A; HK; hexokinase II; H2O2; hydrogen peroxide; IB; intracellular milieu; MCU; mitochondrial Ca2+ uniporter; NCLX
مقالات ISI گیرنده بنزودیازپین محیطی (ترجمه نشده)
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Keywords: گیرنده بنزودیازپین محیطی; AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: گیرنده بنزودیازپین محیطی; 1,25(OH)2D; 1,25 dihydroxy vitamin D (calcitriol); 3βHSD; 3β-hydroxysteroid dehydrogenase; ACAT; acyl transferase; ACTH; adrenocorticotropic hormone; ANT; adenine nucleotide transporter; ER; endoplasmic reticulum; CRAC; cholesterol recognition amino aci
Metal complexes targeting the Translocator Protein 18Â kDa (TSPO)
Keywords: گیرنده بنزودیازپین محیطی; ACBP; acyl coenzyme-A binding protein; AIF; apoptosis inducing factor; ANT; Adenine Nucleotide Translocase; B; boron; BDZ; benzodiazepine; BFC approach; bifunctional chelate approach; BNCT; Boron Neutron Capture Therapy; CBR; Central-type Benzodiazepine R
Short communicationDBI/ACBP loss-of-function does not affect anxiety-like behaviour but reduces anxiolytic responses to diazepam in mice
Keywords: گیرنده بنزودیازپین محیطی; ACBP; acyl-CoA binding protein; DBI; diazepam binding inhibitor; GABA; gamma-aminobutyric acid; CBR; central benzodiazepine receptor; PBR; peripheral benzodiazepine receptor; CNS; central nervous system; GFAP; glial fibrillary acidic protein; ICV; intrace
Research reportOver-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice
Keywords: گیرنده بنزودیازپین محیطی; AD; Alzheimer's disease; EGFP; enhanced green fluorescence protein; GABA; γ-aminobutyric acid; HSD; hydroxysteroid dehydrogenase; LPS; lipopolysaccharide; MWM; Morris water maze; PBR; peripheral benzodiazepine receptor; PVDF; polyvinylidene fluoride; SEM
TSPO Finds NOX2 in Microglia for Redox Homeostasis
Keywords: گیرنده بنزودیازپین محیطی; TSPO; peripheral benzodiazepine receptor; NADPH oxidase (NOX2); redox homeostasis; microglia
A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation
Keywords: گیرنده بنزودیازپین محیطی; PET; Stroke; Peripheral benzodiazepine receptor; PBR; TSPO: neuroinflammation;
Lost in translocation: the functions of the 18-kD translocator protein
Keywords: گیرنده بنزودیازپین محیطی; neuroinflammation; neuroimaging; peripheral benzodiazepine receptor; heme metabolism; REV-ERBα; mitochondrial permeability transition pore; cholesterol
Acitretin affects bioenergetics of liver mitochondria and promotes mitochondrial permeability transition: Potential mechanisms of hepatotoxicity
Keywords: گیرنده بنزودیازپین محیطی; ANT; adenine nucleotide translocase; Asc; ascorbate; BSA; bovine serum albumin; CAT; carboxyatractyloside; CyA; cyclosporine A; CYPD; cyclophilin D; Cys; cysteine; DTT; dithiothreitol; EGTA; NNNâ²N-tetraacetic acid; ER; estrogen receptor; FCCP; carbonyl
Effects of peripheral benzodiazepine receptor ligand Ro5-4864 in four animal models of acute lung injury
Keywords: گیرنده بنزودیازپین محیطی; Acute lung injury; α-Naphthylthiourea; Cecal ligation and puncture; Lipopolysaccharide; Mesenteric ischemia/reperfusion; Peripheral benzodiazepine receptor; Ro5-4864
Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis
Keywords: گیرنده بنزودیازپین محیطی; 19-Atriol; 5-androsten-3b,17,19-triol; 22R-HC; 22R-hydroxycholesterol; cAMP; cyclic adenosine monophosphate; CRAC; cholesterol recognition/interaction amino acid consensus; CYP11A1; cytochrome P450 11A1; dbcAMP; dibutyryl cyclic adenosine monophosphate; M
Searching for Neuropathology: Gliosis in Schizophrenia
Keywords: گیرنده بنزودیازپین محیطی; Astrocytes; glial fibrillary acidic protein; gliosis; human brain; microglia; peripheral benzodiazepine receptor; positron emission tomography
Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis
Keywords: گیرنده بنزودیازپین محیطی; Atherosclerosis; [3H]DAA; [3H](R)-PK11195; Peripheral benzodiazepine receptor; Translocator protein; Macrophage; Inflammation;
4′-Chlorodiazepam — Agonist of peripheral benzodiazepine receptors as a protecting factor in IL-1 induced deregulation of collagen biosynthesis in cultured human chondrocytes
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Ro-54864; Pk-11195; Chondrocyte; IL-1β
Synthesis, structure and affinity of novel 3-alkoxy-1,2-dihydro-3H-1,4-benzodiazepin-2-ones for CNS central and peripheral benzodiazepine receptors
Keywords: گیرنده بنزودیازپین محیطی; 3-alkoxy-1,2-dihydro-3H-1,4-bezodiazepin-2-ones; Enantiomer; Central benzodiazepine receptor; Peripheral benzodiazepine receptor; Affinity; X-ray analysisCBR, central benzodiazepine receptor; PBR, peripheral benzodiazepine receptor; BD, benzodiazepines; G
TLN-4601 peripheral benzodiazepine receptor (PBR/TSPO) binding properties do not mediate apoptosis but confer tumor-specific accumulation
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Translocator protein; TLN-4601; Apoptosis; Tumor accumulation;
Intracranial electrode implantation produces regional neuroinflammation and memory deficits in rats
Keywords: گیرنده بنزودیازپین محیطی; Deep brain stimulation; Brain injury; Peripheral Benzodiazepine Receptor; Translocator protein; Autoradiography; Novel Object Recognition
Synthesis of [125I]iodoDPA-713: A new probe for imaging inflammation
Keywords: گیرنده بنزودیازپین محیطی; TSPO; translocator protein; [125I]iodoDPA-713; N,N-diethyl-2-[2-(3-[125I]iodo-4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]acetamide; PK11195; N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide; SPECT; single photon emission
Translocator protein (18 kDa) TSPO: An emerging therapeutic target in neurotrauma
Keywords: گیرنده بنزودیازپین محیطی; Traumatic brain injury; Spinal cord injury; Translocator protein; Peripheral benzodiazepine receptor; Cell death; Regeneration; Neurogenesis; Neurosteroids
Interactions of peripheral-type benzodiazepine receptor with diamino acid derivatives of protoporphyrin IX
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Porphyrin derivatives; Binding affinities
Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3α-reduced neurosteroids
Keywords: گیرنده بنزودیازپین محیطی; Nociception; Neuropathic pain; Neurosteroid; Peripheral benzodiazepine receptor; Mitochondria; Allodynia; Hyperalgesia; Allopregnanolone;
Synthesis of [11C]FEDAA1106 as a new PET imaging probe of peripheral benzodiazepine receptor expression
Keywords: گیرنده بنزودیازپین محیطی; Positron emission tomography; Peripheral benzodiazepine receptor; [11C]FEDAA1106; Brain and tumor imagingPBR, peripheral benzodiazepine receptor; PET, positron emission tomography; HPLC, high pressure liquid chromatography; EOB, end of bombardment; EOS, e
PBRL, a putative peripheral benzodiazepine receptor, in primitive erythropoiesis
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; PBR; PBRL; Chicken; Chick; Erythropoiesis; Hematopoiesis; Hemoglobin; Globin; Heme; Ferrochelatase; Coproporphyrinogen decarboxylase; Blood; Erythrocyte; Mitochondria; Proteomics; Shot-gun; Mass spectrometry
PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET
Keywords: گیرنده بنزودیازپین محیطی; Alzheimer's disease; Microglia; PET; PK11195; Peripheral benzodiazepine receptor; Astrocyte
Spinal translocator protein (TSPO) modulates pain behavior in rats with CFA-induced monoarthritis
Keywords: گیرنده بنزودیازپین محیطی; Translocator protein 18 kDa; TSPO; Peripheral benzodiazepine receptor; Pain; Inflammation; Inflammatory pain; Arthritis; Spinal cord
Autoradiographical imaging of PPARγ agonist effects on PBR/TSPO binding in TASTPM mice
Keywords: گیرنده بنزودیازپین محیطی; TASTPM mice; [3H](R)-PK11195; [3H]DPA-713; Autoradiography; Pioglitazone; Ciglitazone; Microglia; Peripheral benzodiazepine receptor; Translocator protein (18 kDa)
Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states
Keywords: گیرنده بنزودیازپین محیطی; Steroid biosynthesis; Translocator protein; Steroidogenic acute regulatory protein; Peripheral benzodiazepine receptor
Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: An autoradiographic study with [3H]PK 11195
Keywords: گیرنده بنزودیازپین محیطی; Atherosclerosis; Macrophage; Peripheral benzodiazepine receptor; [3H]PK 11195; Imaging; Nuclear medicine; CD68
Increased Binding of Peripheral Benzodiazepine Receptor in Alzheimer's Disease Measured by Positron Emission Tomography with [11C]DAA1106
Keywords: گیرنده بنزودیازپین محیطی; Alzheimer's disease; microglia; peripheral benzodiazepine receptor; positron emission tomography; [11C]DAA1106
Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors
Keywords: گیرنده بنزودیازپین محیطی; Positron emission tomography; Peripheral benzodiazepine receptor; Imidazopyridineacetamides; Radiosynthesis; Neurodegenerative processes; Alzheimer disease
Ãtifoxine, neurostéroïdes et anxiété
Keywords: گیرنده بنزودیازپین محیطی; Récepteur GABAA; Transmission synaptique inhibitrice; Modulation allostérique; Neurostéroïdogénèse; Récepteur périphérique des benzodiazépines; Anxiolytiques; GABAA receptor; Inhibitory synaptic transmission; Allosteric modulation; Neurosteroido
Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks
Keywords: گیرنده بنزودیازپین محیطی; Cholesterol; Forced swim test; Antidepressant activity; Memory; Peripheral benzodiazepine receptor
Synthesis and structure–activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem
Keywords: گیرنده بنزودیازپین محیطی; PBR; Peripheral benzodiazepine receptor; Palladium-catalyzed allylation; X-ray crystallography
The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: Implications for PET imaging of neuroinflammation in lentiviral encephalitis
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Macrophages; PET; DAA1106; HIV encephalitis; PK11195; SIV encephalitis
Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors
Keywords: گیرنده بنزودیازپین محیطی; Positron emission tomography; Peripheral benzodiazepine receptor; Rats; Microglia
Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor
Keywords: گیرنده بنزودیازپین محیطی; PK11195; Fluorine-18; Positron emission tomography; Inflammation; Peripheral benzodiazepine receptor
Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function
Keywords: گیرنده بنزودیازپین محیطی; ACTH; adrenocorticotropic hormone; CRF; corticotropin-releasing factor; GABA; γ-aminobutyric acid; GHB; γ-hydroxybutyrate; HPA; hypothalamic-pituitary-adrenal; IPSC; inhibitory postsynaptic current; mIPSC; miniature IPSC; PBR; peripheral benzodiazep
Peripheral benzodiazepine receptor ligand, PK11195 induces mitochondria cytochrome c release and dissipation of mitochondria potential via induction of mitochondria permeability transition
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; PK11195; Mitochondria permeability transition
An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells
Keywords: گیرنده بنزودیازپین محیطی; AA; arachidonic acid; StAR protein; steroidogenic acute regulatory protein; cAMP; cyclic 3â²-5â²-adenosine monophosphate; P450scc; side chain cleavage cytochrome P450; PBR; peripheral benzodiazepine receptor; Acot2; mitochondrial acyl-CoA thioesterase
PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Neuroinflammation; Small animal PET; Cerebral ischemia; Activated microglia
Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; Macrophages; PK11195; PI3-kinase; HIV encephalitis; SIV encephalitis
Strategy for improved [11C]DAA1106 radiosynthesis and in vivo peripheral benzodiazepine receptor imaging using microPET, evaluation of [11C]DAA1106
Keywords: گیرنده بنزودیازپین محیطی; [11C]DAA1106; Peripheral benzodiazepine receptor; Positron emission topography (PET); MicroPET; In vivo imaging; Ex vivo binding
Positron Emission Tomography Imaging of Neuroinflammation
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; PBR; PK11195; microglia; neuroinflammation; PET; brain;
Molecular effectors of multiple cell death pathways initiated by photodynamic therapy
Keywords: گیرنده بنزودیازپین محیطی; 1O2; singlet oxygen; ÎÏm; mitochondrial transmembrane potential; [Ca2+]cyt; cytosolic Ca2+-concentration; AlPc; aluminum phthalocyanine; ALA; 5-aminolevulinic acid; AIF; apoptosis inducing factor; ANT; adenine nucleotide translocator; Apaf-1; apoptosis
Stress, ethanol, and neuroactive steroids
Keywords: گیرنده بنزودیازپین محیطی; ACTH; Adrenocorticotropic hormone; ADX; Adrenalectomized; CRF; Corticotropin-releasing factor; DBI; Diazepam binding inhibitor; GABA; γ-aminobutyric acid; GHB; γ-hydroxybutyrate; HPA; Hypothalamic-pituitary-adrenal; IPSC; Inhibitory postsynaptic cur
The apparent positive cooperativity of in vivo [3H]PK-11195 binding in mouse fibrosarcoma
Keywords: گیرنده بنزودیازپین محیطی; Fibrosarcoma; Peripheral benzodiazepine receptor; PK-11195; In vivo binding
Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate
Keywords: گیرنده بنزودیازپین محیطی; Peripheral benzodiazepine receptor; 11C; Positron emission tomography; Methyl triflate
Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: Synaptocrinology
Keywords: گیرنده بنزودیازپین محیطی; neurosteroid; P450; hippocampus; estradiol; endocrine disrupter; BPA; bisphenol A; DES; diethylstilbestrol; DHEA; dehydroepiandrosterone; LTP; long-term potentiation; PBR; peripheral benzodiazepine receptor; PREG; pregnenolone; RNase; ribonuclease; StAR;
Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation
Keywords: گیرنده بنزودیازپین محیطی; Primary cell culture; Neurons; Astrocytes; Mitochondria; Isolation; Nitrogen cavitation; Peripheral benzodiazepine receptor;