Keywords: مدل سازی فارماکوکینتیک; Budesonide; Formoterol; Pharmacokinetic modeling; Asthma; AIC; akaike information criterion; ANOVA; analysis of variance; BE; bioequivalence; BIC; bayesian information criterion; BMI; body mass index; BSV%; percent between subject variability; BUD; budeso
مقالات ISI مدل سازی فارماکوکینتیک (ترجمه نشده)
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Keywords: مدل سازی فارماکوکینتیک; Precision medicine; Pharmacokinetic modeling; Constraint-based modeling; Drug metabolism; Gut microbiota;
Keywords: مدل سازی فارماکوکینتیک; Retina; Vitreous; Choroid; Topical; Intravitreal; Sub-conjunctival; Suprachoroidal; Clearance; Distribution; Pharmacokinetic modeling; Transport;
Keywords: مدل سازی فارماکوکینتیک; Hydrophobic salt formation; Memantine; Long acting injection; Nanocrystals; Pharmacokinetic modeling; High pressure homogenization; Extended release; AD; Alzheimer's disease; NMDA; N-methyl-d-aspartic acid; MEM HCl; memantine hydrochloride; PAM; pamoic
Keywords: مدل سازی فارماکوکینتیک; High pressure homogenizer; Satranidazole; Span 20; HPMC E-5; Bioavailability; Pharmacokinetic modeling;
Keywords: مدل سازی فارماکوکینتیک; Topiramate; Dosing; Extended-release; Pharmacokinetic modeling; Nonadherence;
Keywords: مدل سازی فارماکوکینتیک; Dynamic contrast enhanced (DCE)-MRI; Pharmacokinetic modeling; Independent component analysis (ICA); Adaptive complex ICA; Prostate cancer;
Keywords: مدل سازی فارماکوکینتیک; Pharmacokinetic modeling; Tofts; DCE-MRI; Simulations;
Keywords: مدل سازی فارماکوکینتیک; PBDE; Exposure; Intake; Biomonitoring; Intrinsic elimination half-lives; Pharmacokinetic modeling;
Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modeling
Keywords: مدل سازی فارماکوکینتیک; Pharmacokinetic modeling; Targeted contrast agent; Intratumoral kinetics; Tumor microenvironment; Hypoxia; Multispectral optoacoustic imaging;
Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria
Keywords: مدل سازی فارماکوکینتیک; Preclinical studies; Enzyme replacement therapy; Safety; Toxicity; Pharmacokinetic modeling;
Effect of β-elemene on the kinetics of intracellular transport of d-luciferin potassium salt (ABC substrate) in doxorubicin-resistant breast cancer cells and the associated molecular mechanism
Keywords: مدل سازی فارماکوکینتیک; ABC transporters; ATP-binding cassette transporters; AUC; area under the curve; β-ELE; β-elemene; BLI; bioluminescence imaging; BLIrel; relative bioluminescence imaging; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DOX; doxorubici
Robust and efficient pharmacokinetic parameter non-linear least squares estimation for dynamic contrast enhanced MRI of the prostate
Keywords: مدل سازی فارماکوکینتیک; Prostate cancer; Dynamic-contrast-enhanced magnetic resonance imaging; Pharmacokinetic modeling; Perfusion; Multi-parametric magnetic resonance imaging;
Contribution of neuroinflammation to changes in [11C]flumazenil binding in the rat brain: Evaluation of the inflamed pons as reference tissue
Keywords: مدل سازی فارماکوکینتیک; [11C]flumazenil; GABA; PET; Neuroinflammation; Pharmacokinetic modeling; Herpes simplex encephalitis;
Polyfluoroalkyl substance exposure in the Mid-Ohio River Valley, 1991-2012
Keywords: مدل سازی فارماکوکینتیک; Biomonitoring; Drinking water contaminants; Granular activated carbon (GAC); Per- and polyfluoroalkyl substances (PFAS); Pharmacokinetic modeling;
MR Imaging
Keywords: مدل سازی فارماکوکینتیک; Abbreviated breast MR imaging; Pharmacokinetic modeling; Diffusion-weighted imaging;
Modeling of aceclofenac metabolism to major metabolites in healthy volunteers
Keywords: مدل سازی فارماکوکینتیک; Aceclofenac; Metabolism; 4â²-Hydroxydiclofenac, Diclofenac; 4â²-Hydroxydiclofenac; Pharmacokinetic modeling; Human;
External manipulation of nanostructure in photoresponsive lipid depot matrix to control and predict drug release in vivo
Keywords: مدل سازی فارماکوکینتیک; Photothermal activation; Lipid; Liquid crystalline mesophase; Triggerable drug delivery; Cubic phase; Pharmacokinetic modeling
Prenatal and early-life polychlorinated biphenyl (PCB) levels and behavior in Inuit preschoolers
Keywords: مدل سازی فارماکوکینتیک; IQR, Interquartile range; PCB, Polychlorinated biphenyls; PCB-153, 2,2′,4,4′,5,5′-HexachlorobiphenylPolychlorinated biphenyls (PCBs); Behavior; Preschoolers; Pharmacokinetic modeling; Postnatal exposure
Reconstructing exposures from biomarkers using exposure-pharmacokinetic modeling - A case study with carbaryl
Keywords: مدل سازی فارماکوکینتیک; Exposure reconstruction; Biomarker interpretation; Pharmacokinetic modeling; Physiologically based pharmacokinetic model; Carbaryl; Markov Chain Monte Carlo; Discretized Bayesian; Exposure conversion factor; CARES; Population-based biomonitoring;
Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment
Keywords: مدل سازی فارماکوکینتیک; DCE-MRI; Gd-complexes; Pharmacokinetic modeling; Clustering; Antiangiogenic; Tumor heterogeneity;
A comparison of individual and population-derived vascular input functions for quantitative DCE-MRI in rats
Keywords: مدل سازی فارماکوکینتیک; MRI; Dynamic contrast; DCE; Tumor; Pharmacokinetic modeling; Input function;
A comparison of two methods for estimating DCE-MRI parameters via individual and cohort based AIFs in prostate cancer: A step towards practical implementation
Keywords: مدل سازی فارماکوکینتیک; Prostate cancer; DCE-MRI; Arterial Input Function; Pharmacokinetic modeling; Quantitative imaging
Integration of pharmacokinetic and NRF2 system biology models to describe reactive oxygen species production and subsequent glutathione depletion in liver microfluidic biochips after flutamide exposure
Keywords: مدل سازی فارماکوکینتیک; Nrf2 systems biology modeling; Pharmacokinetic modeling; Microfluidic biochips; Hepatocytes; Flutamide;
[123I]-IBVM SPECT imaging of cholinergic systems in multiple system atrophy: A specific alteration of the ponto-thalamic cholinergic pathways (Ch5–Ch6)
Keywords: مدل سازی فارماکوکینتیک; Single Photon Emission Computed Tomography; [123I]-iodobenzovesamicol; Vesicular acetylcholine transporter; Multiple System Atrophy; Pharmacokinetic modeling
A preclinical pharmacokinetic modeling approach to the biopharmaceutical characterization of immediate and microsphere-based sustained release pulmonary formulations of rifampicin
Keywords: مدل سازی فارماکوکینتیک; PLGA microsphere; Cyclodextrin; Pharmacokinetic modeling; Rifampicin; Rat; Lung deliveryEA, ethyl acetate; HPβCD, 2-hydroxypropyl-β-cyclodextrin; PVA, polyvinyl alcohol; RIF, rifampicin; CL, clearance
Assessment of Prostate Cancer Aggressiveness Using Dynamic Contrast-enhanced Magnetic Resonance Imaging at 3 T
Keywords: مدل سازی فارماکوکینتیک; Dynamic contrast-enhanced MRI; Pharmacokinetic modeling; Prostate cancer; Prostate cancer aggressiveness; Validation study
Signal-to-noise ratio, contrast-to-noise ratio and pharmacokinetic modeling considerations in dynamic contrast-enhanced magnetic resonance imaging
Keywords: مدل سازی فارماکوکینتیک; Dynamic contrast-enhanced; Signal-to-noise; Contrast-to-noise; Pharmacokinetic modeling; Water exchange
Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer
Keywords: مدل سازی فارماکوکینتیک; EGFR-mutant lung cancer, Erlotinib; Evolutionary cancer modeling; Pharmacokinetic modeling; Acquired resistance; EGFR T790M mutation
Use of unbound volumes of drug distribution in pharmacokinetic calculations
Keywords: مدل سازی فارماکوکینتیک; Volume of distribution; Plasma protein binding; Displacement of drug from plasma proteins; Pharmacokinetic modeling
The influence of dissolution conditions on the drug ADME phenomena
Keywords: مدل سازی فارماکوکینتیک; Dissolution; Pharmacokinetic modeling; Enteric coated; ADME
Tumor perfusion increases during hypofractionated short-course radiotherapy in rectal cancer: Sequential perfusion-CT findings
Keywords: مدل سازی فارماکوکینتیک; Perfusion-CT; Pharmacokinetic modeling; Rectal cancer; Tumor perfusion; Short-course hypofractionated radiotherapy
A simple pharmacokinetic model linking plasma progesterone concentrations with the hormone released from bovine intravaginal inserts
Keywords: مدل سازی فارماکوکینتیک; Progesterone; Bovine intravaginal insert; Pharmacokinetics; First uterine pass effect; Pharmacokinetic modeling
Use of simple pharmacokinetic modeling to characterize exposure of Australians to perfluorooctanoic acid and perfluorooctane sulfonic acid
Keywords: مدل سازی فارماکوکینتیک; Perfluorooctanoic acid; PFOA; Perfluorooctane sulfonic acid; PFOS; Pharmacokinetic modeling; Blood monitoring; Australia
Feasibility of using limited-population-based average R10 for pharmacokinetic modeling of osteosarcoma dynamic contrast-enhanced magnetic resonance imaging data
Keywords: مدل سازی فارماکوکینتیک; Dynamic contrast-enhanced MRI; Osteosarcoma; R1; Pharmacokinetic modeling; Ktrans; ve
Pharmacokinetic evaluation and modeling of formulated levodopa intranasal delivery systems
Keywords: مدل سازی فارماکوکینتیک; Levodopa; Nasal delivery; Pharmacokinetic modeling
Pharmacokinetic MR analysis of the cartilage is influenced by field strength
Keywords: مدل سازی فارماکوکینتیک; Cartilage; Field strength; Pharmacokinetic modeling; Contrast-enhanced MR; Reproducibility;
Despite irreversible binding, PET tracer [11C]-SA5845 is suitable for imaging of drug competition at sigma receptors—The cases of ketamine and haloperidol
Keywords: مدل سازی فارماکوکینتیک; Sigma receptor; Positron emission tomography; Pharmacokinetic modeling; Patlak analysis; Neuroreceptor mapping; Competition
Comparing single and repeated dosimetry data for perfluorooctane sulfonate in rats
Keywords: مدل سازی فارماکوکینتیک; Perfluorooctane sulfonate; Pharmacokinetic modeling; PBPK
Time dependencies in perfluorooctylacids disposition in rat and monkeys: A kinetic analysis
Keywords: مدل سازی فارماکوکینتیک; Perfluorooctanoate; Perfluorosulfonate; Renal resorption; Pharmacokinetic modeling
Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI
Keywords: مدل سازی فارماکوکینتیک; Breast lesion; DCE-MRI; Gd-DTPA; Pharmacokinetic modeling
PATIENT VARIABILITY AND UNCERTAINTY QUANTIFICATION IN ANESTHESIA: PART I – PKPD MODELING AND IDENTIFICATION
Keywords: مدل سازی فارماکوکینتیک; Anesthesia closed-loop control; Pharmacokinetic modeling; Pharmacodynamic modeling; Uncertainty; Propofol
Carrier-mediated processes at several rat brain interfaces determine the neuropharmacokinetics of morphine and morphine-6-β-d-glucuronide
Keywords: مدل سازی فارماکوکینتیک; Morphine; Morphine-6-β-d-glucuronide; Brain transporters; Brain distribution; Pharmacokinetic modeling; Microdialysis; Probenecid
A novel simultaneous modeling approach to estimate linearity of pharmacokinetic parameters, including saturation of intestinal efflux, in the rat
Keywords: مدل سازی فارماکوکینتیک; Pharmacokinetic modeling; Intestinal efflux; Accelerated infusion; Pharmacokinetic linearity; In vivo;
Introduction to Automated Drug Delivery in Clinical Anesthesia
Keywords: مدل سازی فارماکوکینتیک; Balanced Anesthesia; Closed-Loop Anesthesia; Cortical Monitoring; Autonomic Monitoring; Pharmacokinetic Modeling; Pharmacodynamic Modeling;