Keywords: خواص فارماکوکینتیک; Aromatase inhibitor; Microdosing clinical trial; Cassette dosing approach; LC-MS/MS; Pharmacokinetic properties; First in human study;
مقالات ISI خواص فارماکوکینتیک (ترجمه نشده)
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Keywords: خواص فارماکوکینتیک; bioavailability; hydroxyprogesterone caproate; pharmacokinetic properties; route of administration; subcutaneous;
Keywords: خواص فارماکوکینتیک; bioavailability; delafloxacin; intravenous; pharmacokinetic properties; safety; tolerability;
Keywords: خواص فارماکوکینتیک; first in human; hypothalamic-pituitary-gonadal axis hormones; pharmacokinetic properties; pharmacodynamic properties; selective androgen receptor modulator;
Keywords: خواص فارماکوکینتیک; extended-release; lorcaserin; obesity; overweight; pharmacokinetic properties;
Keywords: خواص فارماکوکینتیک; empagliflozin; once daily; pharmacodynamics; pharmacokinetic properties; twice daily;
Keywords: خواص فارماکوکینتیک; Cladribine; Fludarabine; Prodrugs; 1,2-, 1,3-Diacylglycerophospholipids; Antiproliferative activity; Pharmacokinetic properties;
Keywords: خواص فارماکوکینتیک; Hedgehog signaling pathway; Inhibitors; SAR; Pharmacokinetic properties;
Keywords: خواص فارماکوکینتیک; Nonsteroidal anti-inflammatory drugs; Biological membranes; Membrane model systems; Pharmacokinetic properties; Therapeutic and toxic actions; ATP; adenosine triphosphate; COX; cyclooxygenase; Coxibs; COX-2 selective inhibitors; CV; cardiovascular; DPPC;
Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties
Keywords: خواص فارماکوکینتیک; Vismodegib; Hedgehog signaling pathway; Basal cell carcinoma; Deuterated drug; Deuterium-hydrogen replacement; Pharmacokinetic properties;
Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study
Keywords: خواص فارماکوکینتیک; absorption; formulation; milk thistle; pharmacokinetic properties; silybin;
Sulfonyl-containing phenyl-pyrrolyl pentane analogues: Novel non-secosteroidal vitamin D receptor modulators with favorable physicochemical properties, pharmacokinetic properties and anti-tumor activity
Keywords: خواص فارماکوکینتیک; Vitamin D receptor (VDR); Non-secosteroidal; Physicochemical properties; Pharmacokinetic properties; Anti-tumor activity;
Identification of a melampomagnolide B analog as a potential lead molecule for treatment of acute myelogenous leukemia
Keywords: خواص فارماکوکینتیک; Leukemia; Melampomagnolide B; Carbamates; LC/MS/MS; Pharmacokinetic properties; Bioavailability;
Population Pharmacokinetics of Valproic Acid in Patients with Mania: Implication for Individualized Dosing Regimens
Keywords: خواص فارماکوکینتیک; bipolar disorder; mania; pharmacokinetic properties; population pharmacokinetic model; valproate; valproic acid;
Ionic liquid mediated stereoselective synthesis of alanine linked hybrid quinazoline-4(3H)-one derivatives perturbing the malarial reductase activity in folate pathway
Keywords: خواص فارماکوکینتیک; Amino acid; 1-n-butyl-3-methylimidazolium tetrafluoroborate; Maestro; Cytotoxicity; [Bmim][BF4]-H2O; Pharmacokinetic properties;
Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent
Keywords: خواص فارماکوکینتیک; ZWLWFCKNFSOIEA-UHFFFAOYSA-N; DKGPAJORZYZGOY-UHFFFAOYSA-N; FSTXHTKEZGSDNN-UHFFFAOYSA-N; DKGPAJORZYZGOY-APZFVMQVSA-N; FSTXHTKEZGSDNN-QYKNYGDISA-N; JMHLCUCEUQCHLL-QDRVQTHMSA-N; UNRCMCRRFYFGFX-JTSGUJNOSA-N; YVBVIJQMJDNVFD-UHFFFAOYSA-N; Plinabulin; Deuterium s
Single-dose Pharmacokinetic Properties and Relative Bioavailability of a Novel Methylphenidate Extended-release Chewable Tablet Compared With Immediate-release Methylphenidate Chewable Tablet
Keywords: خواص فارماکوکینتیک; attention-deficit/hyperactivity disorder; bioavailability; dose forms; methylphenidate; pharmacokinetic properties;
Pharmacokinetic and Pharmacodynamic Properties of Cinacalcet (KRN1493) in Chinese Healthy Volunteers: A Randomized, Open-label, Single Ascending-dose and Multiple-dose, Parallel-group Study
Keywords: خواص فارماکوکینتیک; Chinese healthy volunteers; cinacalcet; pharmacodynamic properties; pharmacokinetic properties; secondary hyperparathyroidism;
Pharmacokinetics, Safety, and Tolerability of Amygdalin and Paeoniflorin After Single and Multiple Intravenous Infusions of Huoxue-Tongluo Lyophilized Powder for Injection in Healthy Chinese Volunteers
Keywords: خواص فارماکوکینتیک; amygdalin; clinical trial; LC-MS/MS; paeoniflorin; pharmacokinetic properties;
Pharmacokinetic Interaction Between Rosuvastatin, Telmisartan, and Amlodipine in Healthy Male Korean Subjects: A Randomized, Open-label, Multiple-dose, 2-period Crossover Study
Keywords: خواص فارماکوکینتیک; amlodipine; drug-drug interaction; pharmacokinetic properties; rosuvastatin; telmisartan;
Pharmacokinetics and Tolerability of Obiltoxaximab: A Report of 5 Healthy Volunteer Studies
Keywords: خواص فارماکوکینتیک; animal rule; anthrax; monoclonal antibody; obiltoxaximab; pharmacokinetic properties;
Selective CB2 receptor agonists. Part 2: Structure–activity relationship studies and optimization of proline-based compounds
Keywords: خواص فارماکوکینتیک; KRHYYFGTRYWZRS-UHFFFAOYSA-N; SNQTVUXJKJMYRL-ZDUSSCGKSA-NCannabinoid receptor 2 (CB2); Proline; Metabolic stability; Solubility; Pharmacokinetic properties
Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors
Keywords: خواص فارماکوکینتیک; AD; Alzheimer disease; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; cGMP; cyclic guanosine monophosphate; OLT; object location test; ORT; object recognition test; PDE; phosphodiesterase; PDE4Is; PDE4 inhibitors; PTC;
Assessing Pharmacokinetic Interactions Between the Sodium Glucose Cotransporter 2 Inhibitor Empagliflozin and Hydrochlorothiazide or Torasemide in Patients With Type 2 Diabetes Mellitus: A Randomized, Open-Label, Crossover Study
Keywords: خواص فارماکوکینتیک; drugâdrug interaction; empagliflozin; hydrochlorothiazide; pharmacokinetic properties; torasemide;
Pharmacokinetic Properties and Effects of PT302 After Repeated Oral Glucose Loading Tests in a Dose-Escalating Study
Keywords: خواص فارماکوکینتیک; exenatide; pharmacodynamic properties; pharmacokinetic properties; sustained release; tolerability;
Pharmacokinetic Comparison of 2 Formulations of Anastrozole (1 mg) in Healthy Korean Male Volunteers: A Randomized, Single-Dose, 2-Period, 2-Sequence, Crossover Study
Keywords: خواص فارماکوکینتیک; anastrozole; bioequivalence; formulation; nonlinear mixed-effect modeling; pharmacokinetic properties; simulation
Tolerability and Pharmacokinetics of a New P-Glycoprotein Inhibitor, HM30181, in Healthy Korean Male Volunteers: Single- and Multiple-Dose Randomized, Placebo-Controlled Studies
Keywords: خواص فارماکوکینتیک; HM30181; P-glycoprotein inhibitor; pharmacokinetic properties; tolerability
Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as potent poly(ADP–ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells
Keywords: خواص فارماکوکینتیک; Anticancer agents; PARP-1 inhibitor; BRCA1 deficient cancer cells; 6-[4-Fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones; Coupling reactions; SAR exploration; Pharmacokinetic properties
Pharmacokinetic properties of crocin (crocetin digentiobiose ester) following oral administration in rats
Keywords: خواص فارماکوکینتیک; Crocin; Crocetin; Pharmacokinetic properties; Oral administration; Rat
Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase
Keywords: خواص فارماکوکینتیک; Soluble epoxide hydrolase (sEH); sEH inhibitors; 1,3-disubstituted ureas; Pharmacokinetic properties
Synthesis and structure–activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists
Keywords: خواص فارماکوکینتیک; Corticotropin-releasing factor 1; Antagonists; SAR; Pharmacokinetic properties
Medicinal Chemical Properties of Successful Central Nervous System Drugs
Keywords: خواص فارماکوکینتیک; CNS drug; ADME (absorption, distribution, metabolism, and excretion); physicochemical properties; pharmacokinetic properties; blood-brain barrier (BBB); QSAR;