Keywords: غربالگری فنوتیپیک; Mycobacterium tuberculosis; Oxadiazoles; Phenotypic screening; Antibacterial;
مقالات ISI غربالگری فنوتیپیک (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: غربالگری فنوتیپیک; Trypanosoma brucei; Triazine; Phenotypic screening; Microsomal stability; Cidal efficacy;
Keywords: غربالگری فنوتیپیک; Trypanosoma brucei; Dimer; Microsomal stability; Phenotypic screening;
Keywords: غربالگری فنوتیپیک; Phenotypic screening; Cochlea; Deafness; Neurite; Statins; In vitro;
Keywords: غربالگری فنوتیپیک; Neural stem cell; Glioblastoma stem cell; CRISPR/Cas9; Genome editing; Phenotypic screening; HCS;
Keywords: غربالگری فنوتیپیک; Neuropharmacology; Systems pharmacology; Reductionism; Multi-target drug; Phenotypic screening; Emergent properties; Serendipity;
Keywords: غربالگری فنوتیپیک; Tuberculosis; Mycobacterium; New chemical entities; Phenotypic screening; Drug discovery;
Keywords: غربالگری فنوتیپیک; Antibacterial; Antimicrobial; Topoisomerase II; Phenotypic screening; Discovery strategy;
Keywords: غربالگری فنوتیپیک; Drug discovery; Drug development; Venoms to drugs; Snake venoms; Conus venoms; Phenotypic screening;
Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
Keywords: غربالگری فنوتیپیک; Autophagy; Phenotypic screening; High-throughput screening; Natural products; Medicinal chemistry;
Deciphering defective amelogenesis using in vitro culture systems
Keywords: غربالگری فنوتیپیک; Amelogenesis imperfecta; Cell-cell interaction; Cell-matrix interaction; Dental epithelial cell; Genetic disease; In vitro amelogenesis imperfecta model; Phenotypic screening; Sp6;
A simple phenotypic method for screening of MCR-1-mediated colistin resistance
Keywords: غربالگری فنوتیپیک; Colistin resistance; Colistin-MAC test; DPA-colistin synergy; mcr-1; Phenotypic screening;
Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation
Keywords: غربالگری فنوتیپیک; Pyridine-2-yl guanidine; TNFα inhibitor; Phenotypic screening; Inflammation; Neuropathic pain;
Rapid detection of carbapenemase-producing Acinetobacter baumannii and carbapenem-resistant Enterobacteriaceae using a bioluminescence-based phenotypic method
Keywords: غربالگری فنوتیپیک; CRE; carbapenem-resistant Enterobacteriaceae; CP-CRE; carbapenemase-producing carbapenem-resistant Enterobacteriaceae; non-CP-CRE; non-carbapenemase-producing carbapenem-resistant Enterobacteriaceae; CP-CRA; carbapenemase-producing Acinetobacter spp.; BCD
A novel 384-multiwell microelectrode array for the impedimetric monitoring of Tau protein induced neurodegenerative processes
Keywords: غربالگری فنوتیپیک; Impedance spectroscopy; 384-multiwell microelectrode array; SH-SY5Y cells; Cell-based tauopathy model; Phenotypic screening; Kinase inhibitor SRN-003-556;
Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia
Keywords: غربالگری فنوتیپیک; Mitochondrial ATP; Cardiomyocytes; Hypertrophy; Hypoxia; Phenotypic screening; ATP; adenosine triphosphate; BNP; brain natriuretic peptide; CsA; cyclosporin A; ET-1; endothelin 1; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; FPKM; fragment
Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: A novel EGFR inhibitor from a designed small library
Keywords: غربالگری فنوتیپیک; Antiproliferative hits; EGFR inhibitors; Phenotypic screening; Anticancer cell lines assay; Pyrimidine derivatives;
Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi
Keywords: غربالگری فنوتیپیک; Alpha-pyrones; Leishmania; Trypanosoma cruzi; SAR; Phenotypic screening; AJCLHNYQRKPYFQ-UHFFFAOYSA-N; ADCLDRLWUWHAKC-UHFFFAOYSA-N; ULJWSSHLAKGIKW-UHFFFAOYSA-N; YTMDDHDOCBVTHT-UHFFFAOYSA-N; JRSGUWWIBIQYEB-UHFFFAOYSA-N; SQFXKUVOJMLOFO-UHFFFAOYSA-N; ZGKWGZIF
High content analysis of phagocytic activity and cell morphology with PuntoMorph
Keywords: غربالگری فنوتیپیک; Phagocytosis; High content analysis; Image processing; Phenotypic screening; Microglia; Drug discovery; Morphometry;
Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro
Keywords: غربالگری فنوتیپیک; Wogonin; Antitumor; ROS; Phenotypic screening; Target fishing;
Zebrafish small molecule screens: Taking the phenotypic plunge
Keywords: غربالگری فنوتیپیک; High-throughput screening; Whole-organism screening; Phenotypic screening; Phenome-wide association study;
Phenotypic screening of Arabidopsis T-DNA insertion lines for cell wall mechanical properties revealed ANTHOCYANINLESS2, a cell wall-related gene
Keywords: غربالگری فنوتیپیک; ANTHOCYANINLESS2; Arabidopsis; Cell wall extensibility; Phenotypic screening; Peroxidase; T-DNA insertion line
Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis
Keywords: غربالگری فنوتیپیک; Furoxan; Tuberculosis; Phenotypic screening; Mycobacterium tuberculosis; Antituberculosis agents;
Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target
Keywords: غربالگری فنوتیپیک; Mycobacterium tuberculosis; Topoisomerase I; Essential; Knockdown; Vulnerable; Anziaic acid; Phenotypic screening;
Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes
Keywords: غربالگری فنوتیپیک; Trypanosoma cruzi; Phenotypic screening; Image-based assay; Early drug discovery; MMV Malaria Box; Compound collections
Inhibition of CDK2 promotes inducible regulatory T-cell differentiation through TGFβ-Smad3 signaling pathway
Keywords: غربالگری فنوتیپیک; Regulatory T cells; Foxp3; Phenotypic screening
Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents
Keywords: غربالگری فنوتیپیک; SK; streptokinase; GAS; Group A Streptococcus; HTS; high-throughput screen; SAR; structure-activity relationship; TPSA; topological polar surface area; c Log P; logarithm of the calculated octanol-water partition coefficient; LDA; lithium diisopropy
Discovery of 2-iminobenzimidazoles as potent hepatitis C virus inhibitors with a novel mechanism of action
Keywords: غربالگری فنوتیپیک; Hepatitis C virus; Phenotypic screening; Iminobenzimidazole; Entry; Release
iPS cell derived neuronal cells for drug discovery
Keywords: غربالگری فنوتیپیک; induced pluripotent stem (iPS) cells; disease modeling; drug discovery; phenotypic screening; high content screening; high throughput RT-PCR; expandable neural progenitors
ReviewSystems biology, complexity, and the impact on antiepileptic drug discovery
Keywords: غربالگری فنوتیپیک; Systems biology; Systems/network pharmacology; Drug resistance in epilepsy; Antiepileptic drug; Polypharmacology; Multitarget drug; Phenotypic screening; Modeling; Drug discovery;
Optimization of anti-proliferative activity using a screening approach with a series of bis-heterocyclic G-quadruplex ligands
Keywords: غربالگری فنوتیپیک; Quadruplex; Anti-proliferative; Phenotypic screening; Telomerase; Oxazoles;
Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity
Keywords: غربالگری فنوتیپیک; iPSC; induced pluripotent stem cell; BMC; benchmark concentration; DMSO; dimethyl sulfoxide; AUC; area under the curve; EC50; effective concentration at 50% of the maximum response; iPSC; Calcium flux; Cardiotoxicity; hERG; Phenotypic screening; Predictiv
Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors
Keywords: غربالگری فنوتیپیک; Hepatitis C virus; Phenotypic screening; Hexahydropyrimidine; Diamines; Entry; Release;
Towards a phenotypic screening strategy for emerging β-lactamases in Gram-negative bacilli
Keywords: غربالگری فنوتیپیک; Phenotypic screening; Phenotypic confirmation; ESBL; AmpC; Carbapenemases;
Identification and validation of bioactive small molecule target through phenotypic screening
Keywords: غربالگری فنوتیپیک; ADME; absorption, distribution, metabolism, and excretion; CsA; cyclosporin A; HBC; 4-[3,5-bis-[2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-4,5-dihydro-pyrazol-1-yl]-benzoic acid; HDAC; histone deacetylase; HUVEC; human umbilical vascular endothelial cell; KF;
A robust assay measuring GLUT4 translocation in rat myoblasts overexpressing GLUT4-myc and AS160_v2
Keywords: غربالگری فنوتیپیک; GLUT4 translocation; AS160; HTS; Confocal imaging; Phenotypic screening;
Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis
Keywords: غربالگری فنوتیپیک; Phenotypic screening; African trypanosomiasis; Target identification; Target validation; U50,488;