دانلود مقالات ISI درباره Phosphatidylinositol-4،5-bisphosphate 3-kinase + ترجمه فارسی

عناصر پاسخ آنتی اکسیدان: کشف، کلاس ها، تنظیمات و برنامه های کاربردی بالقوه

Antioxidant response elements: Discovery, classes, regulation and potential applications

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 3-MC; 3-methylcholanthrene; Ah; aryl hydrocarbon; AhE; aryl hydrocarbon receptor; AP-1; activator protein-1; ARE; antioxidant response element; ATF4; activating transcription factor 4; β-NF; β-naphthoflavone; β-NF-RE; β-NF-responsive element; β-TRCP;

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

پروتئین شوک حرارتی 27 به عنوان پیش بینی کننده پیش آگهی در بیماران مبتلا به نارسایی مزمن قلب عمل می کند

Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; AKT; Protein kinase B; BNP; brain natriuretic peptide; CRP; C-reactive protein; eGFR; estimated glomerular filtration rate; HF; heart failure; HFmrEF; heart failure with mid-range ejection fraction; HFpEF; heart failure with preserved ejection fraction; H

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Alarmins in chronic noncommunicable diseases: Atherosclerosis, diabetes and cancer

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Alarmins; Proteomics; Atherosclerosis; Diabetes; Cancer; HSPs; heat shock proteins family; HMGB1; high-mobility group box 1; PRR; pattern recognition receptor; PAMP; pathogen-associated molecular pattern; CAD; coronary artery disease; SMC; smooth muscle c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

توسعه همکاری داروی بیومارکرین در انکولوژی - 20 سال و شمارش

Drug-biomarker co-development in oncology - 20 years and counting

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ADCC; antibody-dependent cell-mediated cytotoxicity; AKT; protein kinase B; ATP; adenosine triphosphate; cfDNA; circulating free DNA; CISH; chromogenic in-situ hybridization; CTC; circulating tumor cells; EGFR; epithelial growth factor receptor; EMT; epit

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

مهار کننده های کیناز وابسته به سیکلین به عنوان درمان سرطان

Inhibitors of cyclin-dependent kinases as cancer therapeutics

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; AML; acute myeloid leukemia; CAK; CDK-activating kinase; CDK; cyclin-dependent kinases; CLL; chronic lymphocytic leukemia; CT; RNA polymerase II C-terminal domain; DLT; dose-limiting toxicities; DSIF; DRB-sensitivity inducing factor; ER; estrogen Receptor

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

سم چینی رینلا پاراگوئه: تاثیرات در طب سنتی و گسترش سلول های سرطان پستان

The Paraguayan Rhinella toad venom: Implications in the traditional medicine and proliferation of breast cancer cells

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; mTOR; mammalian target of rapamycin; MTT; 3-4,5-dimethythiazol-2,5 biphenyl tetrazolium bromide; Rhinella ornata; Rhinella schneideri; Rhinella scitula; Paraguayan toads; Bufadienolide derivatives; Ant

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

نقش اسناد فسفاتیدیلینواستیل-4،5-بیسفسفات 3-کیناز در قاچاق ویسکولار

Role of phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular trafficking

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PI3K; Protein kinase B; AKT; Endocytosis; Exocytosis; Membrane trafficking; Caveolae; Clathrin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

پیامدهای پلاستیکی بیش از حد در هیپوکامپ ناشی از آسفیکسی پریناتال

Consequences of excessive plasticity in the hippocampus induced by perinatal asphyxia

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; NDDs; neurodevelopmental disorders; PA; perinatal asphyxia; GFAP; glial fibrillary acidic protein; MAP-2; Microtubule associate protein-2; NF H/Mp; phosphorylated high and medium molecular weight neurofilaments; NeuN; neuron-specific nuclear protein; OF;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی پتانسیل های درمانی باکالین و آنزیم آلیکلون بائیکالئین برای بدخیمی های هماتولوژیک

Exploring therapeutic potentials of baicalin and its aglycone baicalein for hematological malignancies

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; PDGF-A; platelet-derived growth factor-A; CK2; casein kinase 2; Bcl-2; B-cell lymphoma-2; PARP; poly-(ADP-ribose) polymerase; IAP; inhibitor of apoptosis protein; XIAP; X-linked inhibitor of apoptosis protein; 8-tBid; caspase-8-cleaved Bid; CBF1; C-repeat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

تنظیم سنتز پروتئین عضلانی و اثرات حالت های کاتابولیک

Regulation of muscle protein synthesis and the effects of catabolic states

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 4E-BP1; eIF4E binding protein 1; 5′-UTR; 5′-untranslated region; AMPK; AMP-activated protein kinase; eIF; eukaryotic initiation factor; GCN2; general-control nonderepressible; GEF; guanine nucleotide exchange factor; GSK-3; glycogen synthase kinase-3;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

عوامل و مکانیسم های عضله اسکلتی در بیماری مزمن انسدادی ریه

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Re-evaluating the role of FOXOs in cancer

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

KRAS-Mutant non-small cell lung cancer: From biology to therapy

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation and biological roles of the multifaceted miRNA-23b (MIR23B)

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; miRNAs; MicroRNAs; C9orf3; Chromosome 9 Open Reading Frame 3; pri-miRNAs; primary miRNA; pre-miRNAs; precursor miRNAs; miRISC; miRNA-induced silencing complex; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; ACTA2; smooth muscle α-actin; MYH

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Assay development; Automated microscopy; Breast cancer; Calcium channels; Gene silencing; High content analysis; EGF; Epidermal growth factor; EGFR; Epidermal growth factor receptor; EMT; Epithelial mesenchymal transition; HER2; Human epidermal growth fac

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of natural flavonoids as activators of Nrf2-mediated defense system: Structure-activity relationship and inhibition of intracellular oxidative insults

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Isoflavone; 7-O-methylbiochanin A; Oxidative stress; Nrf2 activator; ARE; antioxidant response element; COPD; chronic obstructive pulmonary disease; γ-GCS; γ-glutamyl cysteine synthetase; GSH; glutathione; HO-1; heme oxygenase-1; Keap1; Kelch-like ECH-a

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Oxidized fish oil injury stress in Megalobrama amblycephala: Evaluated by growth, intestinal physiology, and transcriptome-based PI3K-Akt/NF-κB/TCR inflammatory signaling

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Megalobrama amblycephala; Fish oil; Oxidative stress; PI3K-Akt; NF-κB; TCR; Immunity; TLR2; toll-like receptor 2; PI3K; phosphatidylinositol-4,5-bisphosphate 3-kinase; Akt; RAC serine/threonine-protein kinase; NF-κB; nuclear factor kappa-light-chain-enh

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Single chain antibody(scFv); OX40; Antibody drug conjugate; Drug delivery; Internalization; Thermal stability of antibody; OX40L; OX40 lignad; scFv; single-chain variable fragment; scFvC; scFv carrying a C-terminal cysteine residue; IκB; nuclear factor o

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

E3-ubiquitin ligase NEDD4 enhances bone formation by removing TGFβ1-induced pSMAD1 in immature osteoblast

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; NEDD4; neural precursor cell-expressed, developmentally down-regulated protein 4; TGFβ1; transforming growth factor β1; BMP2; bone morphogenetic protein 2; PI3K; phosphatidylinositol-4,5-bisphosphate 3-kinase; AKT (PKB); protein kinase B; ERK; extracell

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Ovx; Ovariectomy; PTH; Parathyroid Hormone; miRNA; MicroRNA; μCT; Micro-computed tomography; BMD; Bone mineral density; BV/TV; Bone volume/Total volume; SMI; Structural model index; Tb.N; Trabecular number; Conn Dn; Connection density; Tb.Sp; trabecular

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; BLI; bioluminescence imaging; BSA; bovine serum albumin; CTL; cytotoxic T lymphocytes; CRISPR/Cas; Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated nucleases; DEGs; differently expressed genes; DMEM; Dulbecco's modified Eagle's

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

14-3-3γ regulates Copine1-mediated neuronal differentiation in HiB5 hippocampal progenitor cells

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; CPNE1; Copine1; NF; neurofilament; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; AKT; Protein kinase B (PKB);; BiFC; bimolecular fluorescence complementation; VN/VC; N-terminal half/C-terminal half of Venus; IP; immunoprecipitation; MBP; myelin ba

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Apolipoprotein A-IV exerts its anorectic action through a PI3K/Akt signaling pathway in the hypothalamus

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Apolipoprotein; PI3K/Akt signaling; Hypothalamus; Food intake; Obesity; ApoA-IV; apolipoprotein A-IV; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; Akt, also known PKB; protein kinase B; DMSO; dimethyl sulfoxide; PHF; pair-fed HF; aCSF; artificial

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

RhoA/ROCK pathway mediates leptin-induced uPA expression to promote cell invasion in ovarian cancer cells

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; uPA; urokinase plasminogen activator; ObR; leptin receptor; OB-Rb; The long form of leptin receptor; RhoA; Ras homolog gene family, member A; ROCK; Rho-associated coiled-coil-forming protein kinase; siRNA; small interfering RNA; C3; C3 transferase; JAK; J

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

SP and KLF Transcription Factors in Digestive Physiology and Diseases

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Specificity Protein; Krüppel-Like Factor; Digestive System; Cancer; Stem Cells; Proliferation; Differentiation; Development; Apoptosis; Cell Cycle; APC; adenomatous polyposis coli; BAX; B-cell lymphoma 2-like protein 4; BCL2; B-cell lymphoma 2; COX2; c

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 5-HT; 5-hydroxytryptamine; 7,8-DHF; 7,8-dihydroxyflavone; ACh; acetylcholine; AD; adenosine; ADL; activities of daily living; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; 5′AMP-activated protein kinase; BDNF; brain-derived neurotro

دانلود رایگان متن کامل مقاله ISI 91 صفحه سال انتشار : 2017 سفارش ترجمه

Angiotensin II AT2 receptors regulate NGF-mediated neurite outgrowth via the NO-cGMP pathway

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Angiotensin II; Nerve growth factor; Angiotensin II type 2 receptor; NO-cGMP; AKT; protein kinase B; AT1; angiotensin II type 1; AT2; angiotensin II type 2; CGRP; calcitonin gene-related peptide; cGMP; cyclic guanosine monophosphate; DMEM; Dulbecco's-modi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 2-AG; 2-Arachidonoylglycerol; ARA-S; N-arachidonoyl-l-serine; CB1 receptor; cannabinoid receptor 1; CB2 receptor; cannabinoid receptor 2; e-NOS; endothelial nitric oxide synthetase; Erk1/2; extracellular signal-regulated kinases 1and 2; ET-1; Endothelin 1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Nonreceptor tyrosine kinases ITK and BTK negatively regulate mast cell proinflammatory responses to lipopolysaccharide

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Tec; lipopolysaccharide; mast cell; septic hypothermia; TNF-α; NF-κB; MAPKs; PI3K/Akt; ARE; Adenylate-uridylate-rich element; BMMC; Bone marrow-derived mast cell; CBMC; Cord blood-derived mast cell; MAL; MyD88-adaptor like protein; MAPK; Mitogen-act

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Immunoreceptors on neutrophils

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ADCC; antibody-dependent cellular cytotoxicity; ANCAs; anti-neutrophil autoantibodies; Btk; Bruton's tyrosine kinase; DAG; diacyl-glycerol; DAP12; DNAX activation protein of 12 kDa; ERK; extracellular signal-regulated kinase; fMLP; N-Formylmethionine-leu

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Breast cancer; Estrogen receptor; Phytoestrogen; Wedelolactone; AP-1; activator protein 1; CHFCS; charcoal stripped fetal bovine serum; CCND1; cyclin D1; CTSD; cathepsin D; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECL; enhan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Prolactin and the dietary protein/carbohydrate ratio regulate the expression of SNAT2 amino acid transporter in the mammary gland during lactation

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CRE; cAMP response element; DAB; diaminobenzidine; ECL; enhanced chemiluminescence; HPRT1; hypoxanthine phosphoribosyl transferase 1; HPR; horseradish peroxidase; JaK2; janus kinase 2; MAPK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Lipid agonism: The PIP2 paradigm of ligand-gated ion channels

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; AA; arachidonic acid; ASIC; acid-sensing ion channel; ATP; adenosine triphosphate; BK; big conductance potassium channel; Cav; voltage-dependent calcium channel or VDCC; Ci-VSP; Ciona intestinalis voltage-sensitive phosphatase; CoA; coenzyme A; CTD; cytop

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular and cellular pharmacologyAegeline from Aegle marmelos stimulates glucose transport via Akt and Rac1 signaling, and contributes to a cytoskeletal rearrangement through PI3K/Rac1

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; IRS-1; Insulin receptor substrate-1; PI-3-K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; AS160; Akt substrate of 160 kDa; SE; Standard error; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HG-DMEM; High glucose-Dulbecco's Modifi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Role of protein kinase CK2 in the dynamic interaction of platelets, leukocytes and endothelial cells during thrombus formation

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ADP; adenosin diphosphate; DAPI; 4′,6-diamidine-2′-phenylindole dihydrochloride; DMSO; dimethyl sulfoxide; DRB; 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole; ELISA; enzyme-linked immunosorbent assay; ER; endoplasmatic reticulum; FITC; fluorescein is

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cellulose alters the expression of nuclear factor kappa B-related genes and Toll-like receptor-related genes in human peripheral blood mononuclear cells

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ATM; ataxia telangiectasia mutated; AUC; area under the curve; CD; cluster of differentiation; ECIS; electric cell substrate impedance sensing; EU; endotoxin units; FBS; foetal bovine serum; HEK; human embryonic kidney; IL-1Ra; interleukin 1 receptor anta

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of hippocampal synaptic plasticity by BDNF

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; 4E-BPs; eIF4E-binding proteins; 5-HT; 5-hydroxytryptamine; ADF; actin-depolymerising factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived n

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Dual loss of PI3Kα and PI3Kγ signaling leads to an age-dependent cardiomyopathy

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; WT; wildtype; PI3KαDN; phosphatidylinositol-3-kinase alpha dominant negative; PI3KγKO; phosphatidylinositol-3-kinase gamma knockout; PI3KDM; PI3KαDN/PI3KγKO; PI3Kα; class 1 catalytic phosphatidylinositol-3-kinase alpha; PI3Kγ; class 1 catalytic phos

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Sialosignaling: Sialyltransferases as engines of self-fueling loops in cancer progression

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ALL; acute lymphocytic leukemia; AML; acute myeloblastic leukemia; 5-AZA; 5′-azacytidine; BCG; Bacillus Calmette-Guerin; CIN; chromosome instability; DP; degree of polymerization; ECM; extracellular matrix; EGF; epidermal growth factor; EGFR; epiderma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

BRAF inhibitors in cancer therapy

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; BRAF mutation; BRAF inhibitors; Cancer therapy; Resistance mechanisms; Combination therapy; EGFR; epidermal growth factor receptor; MAPK; mitogen-activated protein kinase; PI3K; phosphatidylinositol-4,5-bisphosphate 3-kinase; PFS; progression free surviva

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2014 سفارش ترجمه

HDL and cognition in neurodegenerative disorders

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; ABC; ATP-binding cassette transporter; AD; Alzheimer's disease; Akt; protein kinase B; ALS; amyotrophic lateral sclerosis; apo; apolipoprotein; Aβ; amyloid-β protein; BBB; blood-brain barrier; CAA; cerebral amyloid angiopathy; CE; cholesterol ester; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Analysing the mutational status of PIK3CA in circulating tumor cells from metastatic breast cancer patients

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Circulating tumor cells; Metastatic breast cancer; PIK3CA mutations; SNaPshot assay; PIK3CA; Phosphatidylinositol-4,5-bisphosphate 3-kinase; Catalytic subunit alpha; APC; allophycocyanin; CK-PE; cytokeratin-phycoerythrin; CS; CellSearch®; CTC(s); circula

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Cancer-Associated Fibroblasts; Distal Cholangiocarcinoma; Intrahepatic Cholangiocarcinoma; Molecular Pathogenesis; α-SMA; α-smooth muscle actin; CA19-9; carbohydrate antigen 19-9; CAF; cancer-associated fibroblast; CCA; cholangiocarcinoma; CT; computed

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2

Keywords: Phosphatidylinositol-4،5-bisphosphate 3-kinase; Mouse Model; Gene Expression; Tumor Suppressor Activity; Signaling Pathway; Akt; protein kinase B; CRC; colorectal cancer; ERK; extracellular signal-regulated kinase; FMNL2; formin-like 2; HMGA; high-mobility group AT-hook; MAPK; mitogen-activated prote

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه