Anthranilate phosphoribosyltransferase: Binding determinants for 5â²-phospho-alpha-d-ribosyl-1â²-pyrophosphate (PRPP) and the implications for inhibitor design
Keywords: AnPRT; anthranilate phosphoribosyltransferase; IC50; absolute IC50, that is the concentration of inhibitor which decreased enzyme activity by 50%; Km; Michaelis-Menten constant; Ki; inhibition constant; Mtb; Mycobacterium tuberculosis; PPi; pyrophosphate;