Keywords: asthma; COPD; pulmonary fibrosis; pulmonary hypertension; ADDS; antibody-dependent degranulatory synapse; ASM; airway smooth muscle; β2-AR; β2-adrenergic receptor; Ca2+; calcium ion; CADM1; cell adhesion molecule 1; CD; cluster of differentiation; CPA3;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Artesunate; Airway inflammation; PI3Kδ; HDAC2; Glucocorticoid; Severe asthma;
Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
Combined inhibition of PI3Kδ and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia
Keywords: Acute myeloid leukemia; FLT3; PI3Kδ; CAL101; Synergistic effect;
Piperidinyl-embeded chalcones possessing anti PI3Kδ inhibitory properties exhibit anti-atopic properties in preclinical models
Keywords: PI3Kδ; Chalcones; Basophil degranulation; Allergic properties; Anti-atopic activity;
Effects of AS2541019, a novel selective PI3Kδ inhibitor, on antibody production and hamster to rat xenotransplantation
Keywords: PI3Kδ; B cell immunity; Antibody production; Xenotransplantation;
Identification of highly potent and selective PI3Kδ inhibitors
Keywords: PI3Kδ; Pyrrolotriazine; Autoimmune diseases; Rheumatoid arthritis; Phosphoinositide 3-kinases;
A novel germline gain-of-function variant in PIK3CD
Keywords: Primary immunodeficiency; Activated phosphoinositide 3-kinase δ syndrome; PIK3CD; PI3Kδ;
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors
Keywords: PI3Kδ; 7-Phenylpyrrolo[2,1-f][1,2,4]triazin-4-amine; Autoimmune diseases; Rheumatoid arthritis; Phosphoinositide 3-kinases;
SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (PI3Kδ) inhibitors
Keywords: Chronic lymphocytic leukemia; PI3Kδ; Structure-activity relationship; 5-Alkynyl; Quinazolinone;
Genetic defects in PI3Kδ affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections
Keywords: B cells; PI3Kδ; APDS; B-cell differentiation; Apoptosis;
Discovery and SAR of pyrrolo[2,1-f][1,2,4]triazin-4-amines as potent and selective PI3Kδ inhibitors
Keywords: PI3Kδ; Pyrrolo[2,1-f][1,2,4]triazin-4-amine; Rheumatoid arthritis; Phosphatidylinositol-3 kinases;
Development and pharmacological validation of novel methods of B cell activation in rat whole blood
Keywords: B cell; BTK; Dextran-coupled anti-IgD; Methods; PI3Kδ; Rat; Synergy; SYK; TLR9; Whole blood;
Synthesis and SAR study of potent and selective PI3Kδ inhibitors
Keywords: PI3Kδ; Reversed quinolines; Inflammation; Autoimmune disorders;
Viral infections in asthma and COPD
Keywords: RSV; respiratory syncytial virus; HRV; human rhinovirus; LAI; lower airway infection; AHR; airway hyperresponsiveness; TLR3; Toll-like receptor 3; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-associated gene 5; TRIF; Toll/IL-1R do
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
Keywords: Chronic lymphocytic leukemia; CLL; Microenvironment; Nurselike cells; Stromal cells; CXCR4; CXCL12; B cell receptor; BCR; SYK; BTK; PI3Kδ; Chemokines; Chemokine receptors; T cells; NK cells;
Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function
Keywords: PI3Kδ; phosphoinositide 3-kinase delta; PIP3; phosphoinositide 3,4,5-triphosphates; SH2; Src homology-2; PH; pleckstrin homology; KD; kinase-dead; KO; knockout; BCR; B cell receptor; GPCR; G protein-coupled receptor; TCR; T cell receptor; FcεRI; high af