دانلود مقالات ISI درباره Picup + ترجمه فارسی

بیماری آلزایمر به عنوان الیگوموپاتی

Alzheimer's disease as oligomeropathy

Keywords: Alzheimer's disease; Amyloid β-protein; Oligomers; Oligomeropathy; Aβ; amyloid β-protein; AD; Alzheimer's disease; ADDL; Aβ-derived diffusible ligands; AFM; atomic force microscopy; APP; Aβ precursor protein; APP OSK mice; APP transgenic mice express

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

مهار توده سمی پروتئین آمیوئیدوژنیک: یک استراتژی درمانی برای بیماری های غلط شدن پروتئین

Inhibiting toxic aggregation of amyloidogenic proteins: A therapeutic strategy for protein misfolding diseases

Keywords: AChE; acetylcholinesterase; AD; Alzheimer's disease; AIF; apoptosis induce factor; Aβ; amyloid-beta; BBB; blood brain barrier; CA; caffeic acid; CD; circular dichroism; CGA; chlorogenic acid; CNS; central nervous system; CHOP; C/EBP Homologous Protein; E

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2013 سفارش ترجمه

Supratherapeutic concentrations of cilostazol inhibits β-amyloid oligomerization in vitro

Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; APP; amyloid precursor protein; APS; ammonium persulfate; αS; α-synuclein; CREB; cyclic adenosine monophosphate response element-binding protein; CSZ; cilostazol; DMTs; disease-modifying therapies; EM; e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Residue-specific mobility changes in soluble oligomers of the prion protein define regions involved in aggregation

Keywords: Prion protein; Protein misfolding; Beta oligomer; Solution NMR; PrPSc; infectious particle of misfolded prion protein; PrP; prion protein; PrPc; cellular prion protein; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; CJD; Creutzfeldt

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Proanthocyanidins are the major anti-diabetic components of cinnamon water extract

Keywords: CD; circular dichroism; CWE; cinnamon water extract; EGCG; (−)-epigallocatechin 3-gallate; HFIP; hexafluoroisopropanol; hIAPP; human islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PA; proanthocyanidins; PBS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dissecting the role of disulfide bonds on the amyloid formation of insulin

Keywords: Insulin; Diabetes; Disulfide bonds; Fibrillation; Oligomerization; Hemolysis; TCEP; Tris(2-carboxyethyl)phosphine; CD; circular dichroism; TEM; transmission electron-microscopy; ThT; Thioflavin-T; PICUP; photo-induced cross-linking of unmodified proteins;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-amyloidogenic effects of soybean isoflavones in vitro: Fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils

Keywords: Aβ; amyloid β-protein; AFM; atomic force microscopy; AU; arbitrary unit; CD; circular dichroism; CSF; cerebrospinal fluid; Dai; daidzein; DTT; dithiothreitol; EM; electron microscopy; Equ; (±)-Equol; EM; emission; EX; excitation; fAβs; Aβ fibrils; Fo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals

Keywords: αS; Alpha-synuclein; APS; ammonium persulfate; 1C3; anti-dityrosine specific antibody; syn211; anti-αS specific antibody; AFM; atomic force microscopy; CPS; chronopotentiometric stripping; DLS; dynamic light scattering; ESI-MS; electrospray ionization m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity

Keywords: AD; Alzheimer's diseases; APP; amyloid precursor protein; Aβ; amyloid-β peptide; ACSF; artificial cerebral spinal fluid; BCA; bicinchoninic acid; CF; 5-carboxyfluorescein; DBU; 1,8-diazabicyclo[5,4,0]-undec-7-ene; DCF; dichlorofluorescein diacetate; DIV

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه