Keywords: Clear cell; Ovarian cancer; Aspirin; Survival; PIK3CA;
مقالات ISI (ترجمه نشده)
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Keywords: KRAS; HNF1β; PIK3CA; PPP2R1A; ARID1A;
Keywords: Poroma; porocarcinoma; UV signature; HRAS; TP53; PIK3CA;
Keywords: Biomarker; Brain tumor; Diagnosis; Meningioma; Molecular characterization; Prognosis; Recurrence; AKT1; v-Akt murine thymoma viral oncogene homolog 1; BAP1; BRCA1-associated protein 1; CDKN2A and B; Cyclin-dependent kinase inhibitor 2A and 2B; FAK; Focal
Keywords: Breast cancer; Next-generation sequencing; Somatic mutations; TP53; PIK3CA; Systemic therapy;
Keywords: Head and neck cancer; Clonal evolution; TP53; PIK3CA; MLL2; Tumour heterogeneity; Subclonal selection;
Keywords: Endometrial carcinoma; Genetics; Microsatellite instability; PTEN; PIK3CA; K-RAS; Beta-catenin; Apoptosis; Chromosomal instability; E-cadherin; TP53;
Keywords: Dual EGFR/HER2 inhibitors; Resistance; T790M/L858R mutant EGFR; Irreversible inhibitors; ADMET; Absorption/Distribution/Metabolism/Excretion/Toxicity; Cbl; Casitas B-lineage Lymphoma; c-MET; cellular mesenchymal to epithelial transition factor; DM; double
Keywords: PI3K; phosphatidylinositol 3-kinase; PIK3CA; PI3K catalytic subunit alpha; Akt; protein kinase B; mTOR; mammalian target of the rapamycin pathway; GPCRs; G-protein-coupled-receptors; PTEN; phosphatase and tensin homolog; GAP; GTPase-activating protein; pY
Keywords: Bladder cancer; Genomics; Clinical outcomes; PIK3CA; Mutation
Keywords: Non-small cell lung cancer; Squamous cell carcinoma; Smoking; EGFR; PIK3CA; ALK;
Keywords: Chemotherapy; TNBCtype; Neoadjuvant; PIK3CA; Androgen receptor; TNBC; triple negative breast cancer; pCR; pathological complete response; HR; homologous recombination; EMT; epithelial-mesenchymal-transition; AR; androgen receptor; TILs; tumor-infiltrati
Keywords: AMDIS; automated mass spectral deconvolution and identification system; ANOVA; analysis of variance; EI; electron ionization; ER; estrogen receptor; FH; fumarate hydratase; GC; gas chromatography; HER2; human epidermal growth factor receptor 2; HIF; hypox
Keywords: Small cell lung cancer; Molecular profiling; Genomic aberration; Driver mutation; PIK3CA; EGFR
Keywords: PIK3CA; KRAS; IDH; MET; Biliary;
Keywords: BCR-ABL; breakpoint cluster region-Abelson tyrosine-protein kinase; CD95/FAS; cluster of differentiation 95/cell surface death receptor; DDR1; discoidin domain receptor tyrosine kinase 1; EGFR; epidermal growth factor receptor tyrosine kinase; EF1A2; euka
Pulmonary thromboembolic events in patients with congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities and Klippel-Trénaunay syndrome
Keywords: Pulmonary embolism; CLOVES; Klippel-Trenaunay; PIK3CA;
Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2
Keywords: Buparlisib; Fulvestrant; Hormone receptor-positive breast cancer; Overall survival; PIK3CA; ctDNA;
The landscape of somatic mutations in Indonesian cervical cancer is predominated by the PI3K pathway
Keywords: Cervical carcinoma; somatic mutation; PIK3CA; Indonesia; human papillomavirus; cancer genomics; targeting therapy;
A randomized phase II trial of trastuzumab plus capecitabine versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer previously treated with trastuzumab and taxanes: WJOG6110B/ELTOP
Keywords: Lapatinib; Trastuzumab; Beyond progression; PIK3CA; Brain metastasis; Circulating tumor DNA;
Re-evaluating the role of FOXOs in cancer
Keywords: RTK; receptor tyrosine kinase; GF; growth factor; PI3K; Phosphatidylinositol-4,5-bisphosphate 3-kinase; PKB; protein kinase B; AKT; RAC-alpha serine/threonine-protein kinase; FOXO; forkhead box O; GFR; growth factor receptor; PDPK1; Phosphoinositide-depen
Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway
Keywords: Colorectal cancer; Exosomes; MicroRNA; MiR-10b; Cancer-associated fibroblasts; PIK3CA; PI3K/Akt/mTOR pathway;
MicroRNAs link chronic inflammation in childhood to growth impairment and insulin-resistance
Keywords: ALS; acid-labile subunit; APC; antigen-presenting cell; CXCL2; chemokine (C-X-C motif) ligand 2; ESR; erythrocyte sedimentation rate; FGFR1; fibroblast growth factor receptor 1; FOXO1; Forkhed box O1; FOXP3; forkhead box P3; GH; growth hormone; GHR; growt
Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence
Keywords: Colorectal liver metastases; Gene; KRAS; BRAF; TP53; PIK3CA;
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3Kα-selective inhibitor CYH33 in breast cancer
Keywords: PIK3CA; HER2; Akt; Patient-derived xenograft (PDX);
Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic β-Catenin, PIK3CA and MET
Keywords: Liver tumorigenesis; Shp2; Met; β-Catenin; PIK3CA;
STAT3: The art of multi-tasking of metabolic and immune functions in obesity
Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti
Pulmonary adenocarcinoma with enteric differentiation: Dissecting oncogenic genes alterations with DNA sequencing and FISH analysis
Keywords: Lung adenocarcinoma; Enteric; EGFR; K-RAS; ALK; PIK3CA;
Oncogenic mutations of PIK3CA and HRAS in carcinoma of cervix in South Indian women
Keywords: Oncogenic mutations; Cervical cancer; Peripheral blood; PCR-CTPP method; PIK3CA; Phosphatidylinositol-4,5-Bisphosphate; 3-Kinase Catalytic Subunit Alpha; HRAS; Harvey rat sarcoma viral oncogene homolog; EGF; Epidermal Growth Factor; PDGF; Platelet Derived
Comprehensive genomic profiling (CGP) of ovarian clear cell carcinomas (OCCC) identifies clinically relevant genomic alterations (CRGA) and targeted therapy options
Keywords: Ovarian clear cell carcinoma; PIK3CA; PTEN; Everolimus; Comprehensive genomic profiling;
Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes
Keywords: Mutation; Lung cancer; Adenocarcinoma; EGFR; TP53; PIK3CA; PTEN; Kinase inhibitor; Erlotinib;
Original articleMutation analysis of CTNNB1 gene and the ras pathway genes KRAS, NRAS, BRAF, and PIK3CA in eyelid sebaceous carcinomas
Keywords: Eyelid; Sebaceous carcinoma; CTNNB1; NRAS; BRAF; PIK3CA;
PIK3CA mutations as prognostic factor in squamous cell lung carcinoma
Keywords: Lung cancer; Squamous cell carcinoma; Mutation; PIK3CA; Prognosis;
Molecular alterations in lesions of anogenital mammary-like glands and their mammary counterparts including hidradenoma papilliferum, intraductal papilloma, fibroadenoma and phyllodes tumor
Keywords: PIK3CA; AKT1; Anogenital mammary-like glands; Hidradenoma papilliferum; Fibroadenoma; Phyllodes tumor; Intraductal papilloma; Vulva; Breast;
Original contributionAnalysis of KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer
Keywords: Colorectal cancer; Poorly differentiated clusters; KRAS; PIK3CA; NRAS;
EVA1A inhibits GBM cell proliferation by inducing autophagy and apoptosis
Keywords: GBM; Glioblastoma; EVA1A; Eva-1 homolog A (C. elegans); Ad; Adenovirus; BrdU; bromodeoxyuridine; LC3; Light Chain 3; mTOR; mammalian target of rapamycin; RPS6KB1; ribosomal protein S6 kinases, polypeptide 1; PIK3CA; phosphatidylinositol-4,5-bisphosphate 3
Original ResearchPhase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours
Keywords: Phase I; EGFR; mTOR; PIK3CA; Precision medicine;
Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer
Keywords: Biomarker; Cell-free DNA; Liquid biopsy; Personalised analysis; FGFR3; PIK3CA; Droplet digital polymerase chain reaction;
In this issueKRAS and PIK3CA mutations in colorectal adenocarcinomas correlate with aggressive histological features and behavior
Keywords: Colorectal carcinoma; KRAS; PIK3CA; BRAF; Tumor budding;
Gait disturbance and lower limb pain in a patient with PIK3CA-related disorder
Keywords: PIK3CA; Mosaicism; Macrodactyly; Overgrowth; Neuropathic pain;
PIK3CA mutation in a mixed dysembryoplastic neuroepithelial tumor and rosette forming glioneuronal tumor, a case report and literature review
Keywords: Rosette forming glioneuronal tumor; Dysembryoplastic neuroepithelial tumor; PIK3CA; Case report;
PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: A comprehensive mutational analysis from a multi-institutional cohort
Keywords: Non-small cell lung cancer; Chronic obstructive pulmonary disease; PIK3CA; Nrf2; Next generation sequence;
Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design
Keywords: PIK3CA; PI3K; PIP2; PIP3; Fragment-based drug discovery;
Analysis of PIK3CA mutations and PI3K pathway proteins in advanced gastric cancer
Keywords: Biomarker; Gastric cancer; p-AKT; PIK3CA; PI3K pathway;
Frequent PIK3CA-activating mutations in hidradenoma papilliferums
Keywords: Hidradenoma papilliferum; PIK3CA; AKT1; Intraductal papilloma; Anogenital mammary-like glands;
PIK3CA promotes proliferation and motility but is unassociated with lymph node metastasis or prognosis in esophageal squamous cell carcinoma
Keywords: Esophageal squamous cell carcinoma; PIK3CA; Proliferation; Metastasis; Motility; Prognosis
PIK3CA Mutation, Aspirin Use after Diagnosis and Survival of Colorectal Cancer. A Systematic Review and Meta-analysis of Epidemiological Studies
Keywords: Adjuvant trials; aspirin; colorectal cancer; overall survival; PIK3CA; post-diagnosis use;
Expression and prognostic roles of PIK3CA, JAK2, PD-L1, and PD-L2 in Epstein-Barr virus–associated gastric carcinoma
Keywords: EBVaGC; PIK3CA; JAK2; PD-L1; PD-L2
Low incidence of KRAS, BRAF, and PIK3CA mutations in adenocarcinomas of the ampulla of Vater and their prognostic value
Keywords: Ampulla of Vater; Adenocarcinoma; KRAS; BRAF; PIK3CA; Mutation; Prognosis;
Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma
Keywords: OSCC; Oral Squamous Cell Carcinoma; miRNA; MicroRNA; NGS; Next Generation Sequencing; STRING; Search Tool for Retrieval of Interacting Genes/Proteins; ACTREC; Advanced Centre for Treatment Research and Education in Cancer; HNOCDB; Head Neck Oral Cancer Da