Simvastatin induces NFκB/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells
Keywords: پین 1; Simvastatin (PubChem CID:54454); Bay11-7082 (PubChem CID:5353431); Farnesyl pyrophosphate (PubChem CID:445713); Geranylgeranyl pyrophosphate (PubChem CID:447277); SP600125 (PubChem CID:8515)Simvastatin; NFκB stability; Pin1; JNK1; AP-1; MMP-2/MMP-9