دانلود مقالات ISI درباره Pk11195 + ترجمه فارسی

هویت مولکولی منافذ انتقال نفوذی میتوکندری و نقش آن در آسیب های ایسکمی-رپرفیوژن

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide transporter; ATP; adenine triphosphate; C1QBP; complement component 1Q subcomponent-binding protein; Ca2 +; calcium; CK; creatine kinase; CsA; cyclosporine A; CYCLE; CYCLosporinE A in reperfused acute m

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

تأثیر فعال سازی میکروگلایلیس بر عملکرد عضلانی در بیماری آلزایمر و بیماری پارکینسون دمانس

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia

Keywords: PIB; FDG; PK11195; Alzheimer's disease; Mild cognitive impairment; Parkinson's disease dementia; Correlation;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study

Keywords: Alzheimer's disease; Positron emission tomography; Microglial activation; Amyloid PET; Tau PET; Aβ; Amyloid-β; MMSE; Mini-Mental State Examination; PiB; Pittsburgh compound B; PK11195; 11C-(R)-PK11195; flortaucipir; 18F-flortaucipir; SPM; Statistical pa

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effect of zolpidem against glutamate-induced toxicity is mediated via the PI3K/Akt pathway and inhibited by PK11195

Keywords: ANC; adenine nucleotide carrier; H2O2; hydrogen peroxide; LDH; lactate dehydrogenase; mPTP; mitochondrial permeability transition pore; PI3K; phosphatidylinositol-3-kinase; PK11195; 1-(-2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis of 4-benzylidene-oxazol-5(4H)-imines, structural analogs of PK11195, under Bischler-Napieralski conditions

Keywords: 4-Benzylidene-oxazol-5(4H)imines; Bischler-Napieralski reaction; α,β-Unsaturated acid derivatives; Oxazolones; PK11195;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Evolving understanding of translocator protein 18 kDa (TSPO)

Keywords: TSPO; translocator protein 18 kDa; PBR; peripheral-type benzodiazepine receptor; RsTSPO; TSPO from Rhodobacter sphaeroides; BcTSPO; TSPO from Bacillus cereus; mTSPO; TSPO from mouse; MPTP; mitochondrial permeability transition pore; VDAC; voltage depende

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Combined effect of G3139 and TSPO ligands on Ca2+-induced permeability transition in rat brain mitochondria

Keywords: VDAC; TSPO; Mitochondria; Permeability transition pore; PK11195; G3139ANT, adenine nucleotide translocase; PK11195, 1-(2-Chlorophenyl-N-methylpropyl)-3-isoquinolinecarboxamide; PPIX, protoporphyrin IX; mPTP, mitochondrial permeability transition pore; RBM

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides

Keywords: Anxiolytic activity; Elevated plus maze test; Open field test; PK11195; Pyrrolo[1,2-a]pyrazines; TSPO; Vinyl azides;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Protein-ligand and membrane-ligand interactions in pharmacology: the case of the translocator protein (TSPO)

Keywords: NSAIDs; non-steroidal anti-inflammatory drugs; Pgp; P-glycoprotein; PK11195; 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; Ro5-4863; benzodiazepine 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one; TN

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

In-vivo detection of inflammation and neurodegeneration in the chronic phase after permanent embolic stroke in rats

Keywords: Neuroinflammation; Stroke; Macrosphere model; Microglia; PK11195; Amyloid plaque;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2

Keywords: COX-2; cyclooxygenase-2; DA; dopamine; DMSO; dimethyl sulfoxide; MPTP; 1-Methyl 4-phenyl 1,2,3,6-tetrahydropyridine; 6-OHDA; 6-Hydroxydopamine; PD; Parkinson's disease; PBS; phosphate buffered saline; PACAP; pituitary adenylate cyclase-activating polypept

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease

Keywords: Alzheimer's disease; Inflammation; Microglia; Molecular imaging; Positron emission tomography; PK11195; PPAR-gamma; Transgenic mice;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Release of targeted p53 from the mitochondrion as an early signal during mitochondrial dysfunction

Keywords: p53; Mitochondria; Rotenone; Embryo; PK11195; TspO;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

[11C]PK11195 PET imaging of spinal glial activation after nerve injury in rats

Keywords: Partial sciatic nerve ligation (PSL); Spinal cord; Microglia; PK11195; Translocator protein 18 kDa (TSPO); Positron emission tomography (PET)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Microglial activation in healthy aging

Keywords: Aging; Microglial activation; PK11195; PET; Neurodegeneration

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells

Keywords: Quinolinic acid; PK11195; Glucose metabolism; Glial cell; Rat brain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis of [125I]iodoDPA-713: A new probe for imaging inflammation

Keywords: TSPO; translocator protein; [125I]iodoDPA-713; N,N-diethyl-2-[2-(3-[125I]iodo-4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]acetamide; PK11195; N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide; SPECT; single photon emission

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) syst

Keywords: Peripheral benzodiazepine receptor (PBR); TSPO (18 kDa translocator protein); DAA1106; I-125; PK11195; Vinpocetine; Human brain; Whole hemisphere autoradiography; Receptor binding

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET

Keywords: Alzheimer's disease; Microglia; PET; PK11195; Peripheral benzodiazepine receptor; Astrocyte

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Rapid and efficient radiosynthesis of [123I]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors

Keywords: Radiosynthesis; Single photon emission computed tomography; PK11195; Benzodiazepine; Microglial; Neuroinflammation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of topiramate on seizure susceptibility in kainate-kindled rats: Involvement of peripheral-type benzodiazepine receptors

Keywords: Topiramate; Epilepsy; Peripheral benzodiazepine receptors; PK11195; Hippocampus; Rats

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

Keywords: Alzheimer; Amyloid; Microglia; PIB; PK11195; PET

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195

Keywords: Apoptosis; PK11195; Bcl-2; Ca2+ signalling; Mitochondria; Endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: Preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients

Keywords: Vinpocetine; PK11195; Peripheral benzodiazepine binding site; Glia; Positron emission tomography; Sclerosis multiplex

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: Implications for PET imaging of neuroinflammation in lentiviral encephalitis

Keywords: Peripheral benzodiazepine receptor; Macrophages; PET; DAA1106; HIV encephalitis; PK11195; SIV encephalitis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor

Keywords: PK11195; Fluorine-18; Positron emission tomography; Inflammation; Peripheral benzodiazepine receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Imaging microglial activation in Huntington's disease

Keywords: Huntington's disease; Microglial activation; Emission tomography; PK11195

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner

Keywords: Peripheral benzodiazepine receptor; Macrophages; PK11195; PI3-kinase; HIV encephalitis; SIV encephalitis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Peripheral-type benzodiazepine receptors in bronchoalveolar lavage cells of patients with interstitial lung disease

Keywords: Peripheral benzodiazepine receptors; Interstitial lung disease; PK11195

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Peripheral benzodiazepine receptor ligand, PK11195 induces mitochondria cytochrome c release and dissipation of mitochondria potential via induction of mitochondria permeability transition

Keywords: Peripheral benzodiazepine receptor; PK11195; Mitochondria permeability transition

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

A systematic comparison of kinetic modelling methods generating parametric maps for [11C]-(R)-PK11195

Keywords: PET; Kinetic modelling; Wavelets; Logan plot; DEPICT; Microglia; pk11195;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Positron Emission Tomography Imaging of Neuroinflammation

Keywords: Peripheral benzodiazepine receptor; PBR; PK11195; microglia; neuroinflammation; PET; brain;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

Keywords: PK11195; PET; Parkinson's disease; Microglia; Neuroinflammation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore

Keywords: Leukemia; Apoptosis; Resveratrol; Cyclosporin A; PK11195

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

[11C]Vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies

Keywords: Vinpocetine; PK11195; Peripheral benzodiazepine binding site (PBBS); Monkey brain; Glia; Positron emission tomography (PET);

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum

Keywords: PK11195; Peripheral benzodiazepine receptors; Neuroprotection; Quinolinic acid; Microglia; Inflammation; Oxidative damage;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه