Characterization of rabies pDNA nanoparticulate vaccine in poloxamer 407 gel
Keywords: pDNA; PLGA; Cell uptake; Nanoplex; Immunogenicity; Vaccine stability;
مقالات ISI (ترجمه نشده)
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A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522
Keywords: Drug delivery; Adjuvant; Vaccine; PLGA; Nanomedicine; Liposomes; Glycol chitosan; Mucosal vaccination;
An in-situ forming implant formulation of naltrexone with minimum initial burst release using mixture of PLGA copolymers and ethyl heptanoate as an additive: In-vitro, ex-vivo, and in-vivo release evaluation
Keywords: PLGA; Initial burst release; In situ forming implant; Optimized formulation; Naltrexone;
Nanocrystals of a potent p38 MAPK inhibitor embedded in microparticles: Therapeutic effects in inflammatory and mechanistic murine models of osteoarthritis
Keywords: PH-797804; Biodegradable microparticles; Nanocrystals; Inflammatory and mechanistic mouse models; Osteoarthritis; Intra-articular administration; Extended drug delivery; p38α/β MAPK inhibitor; 99mTc; technetium-99â¯m; AIA; antigen-induced arthritis; DM
Structure, degradation, drug release and mechanical properties relationships of iron-based drug eluting scaffolds: The effects of PLGA
Keywords: PLGA; Porous iron; Iron degradation; Curcumin release; Bone cancer scaffolds;
Fabrication and Use of Poly(d,l-lactide-co-glycolide)-Based Formulations Designed for Modified Release of 5-Fluorouracil
Keywords: 5-FU; 5-fluorouracil; poly(lactic/glycolic) acid (PLGA, PLA); controlled/sustained release/delivery; microparticles; nanoparticles; 5-FU; 5-fluorouracil; dUMP; deoxyuridine monophosphate; DCM; dichloromethane; EPR; enhanced permeation and retention; FdUMP
Fabrication, detection, and analysis of DNA-labeled PLGA particles for environmental transport studies
Keywords: PLGA; DNA; Colloid; Transport;
In-situ forming PLGA implants for intraocular dexamethasone delivery
Keywords: PLGA; In-situ forming implant; Dexamethasone; Autocatalysis; Swelling;
Nanomedicine for the cardiac myocyte: Where are we?
Keywords: 7KC; 7-ketocholesterol; Ang II; Angiotensin II; AT1; Angiotensin II type 1; AT1R; Ang II type 1 receptor; Au; Gold; BIO; 6-Bromoindirubin-3 oxine.; CeO2; Cerium oxide/ceria; CLIO; Cross-linked iron oxide; CNF; Carbon nanofiber; CNT; Carbon nanotube; CsA;
Biomaterial Cues to Direct a Pro-regenerative Phenotype in Macrophages and Schwann Cells
Keywords: CNTF; ciliary neurotrophic factor; CSPG; chondroitin sulfate proteoglycan; DRG; dorsal root ganglia; PNI; peripheral nerve injury; ECM; extracellular matrix; HA; hyaluronic acid; IFNy; interferon-y; iNOS; inducible nitric oxide synthase; LPS; lipopolysacc
Polyester based nanovehicles for siRNA delivery
Keywords: Polyester; siRNA delivery; PLGA; PLA; PCL; Polyhydroxyalkanoates;
Controllable preparation of SB-3CT loaded PLGA microcapsules for traumatic-brain-injury pharmaco-therapy
Keywords: TBI; SB-3CT; PLGA; Encapsulation; Microfluidics;
Transdermal immunomodulation: Principles, advances and perspectives
Keywords: AD; atopic dermatitis; AHR; airway hyper responsiveness; APCs; antigen-presenting cells; AS-ODN; antisense oligonucleotide; BCG; Bacillus Calmette-Guérin; CTLs; cytotoxic T cells; dDCs; dermal dendritic cells; DfE; Dermatophagoides farinae extract; EAE;
Laponite®: A key nanoplatform for biomedical applications?
Keywords: Laponite; Nanomedicine; Drug delivery; Bioimaging; Tissue engineering and regenerative medicine; Acetal-PEG-b-PAMA; (α-acetal-poly(ethylene glycol)-block-[poly(2-(N,N-dimethylamino) ethyl methacrylate)]; ALP; alkaline phosphatase; APMES; 3-aminopropyldim
Current and future technological advances in transdermal gene delivery
Keywords: AuPT; gold nanoparticles; CpG-ODN; cytosine-phosphate-guanosine oligodeoxynucleotide; CPPs; cell penetrating peptides; CTAB; cetyltrimethylammonium bromide; CTLs; cytotoxic T lymphocytes; DCs; dendritic cells; DC-Chol; 3β-[N-(Nâ²,Nâ²-dimethylaminoe
A bird's eye view of nanoparticles prepared by electrospraying: advancements in drug delivery field
Keywords: Electrospraying; Nanoparticles; Electrohydrodynamic atomization; Controlled release; Solubility enhancement; Surface morphology; AA; Acetic Acid; BD; Beclomethasone Dipropionate; BSA; Bovine Serum Albumin; C; Critical Polymer concentration; CD; Circular D
Nanomedicines and gene therapy for the delivery of growth factors to improve perfusion and oxygenation in wound healing
Keywords: Ang-1; angiopoietin 1; AP-57; antimicrobial peptide 57; CS; chitosan; Cur; curcumin; ECM; extracellular matrix; EGF; epidermal growth factor; eNOS; endothelial nitric oxide synthase; EPCs; endothelial progenitor cells; EPR; electron paramagnetic resonance
Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics
Keywords: PLGA; Drug delivery; Protein and nucleic acid; Controlled and stimuli-responsive release;
Nanopharmaceuticals for wound healing - Lost in translation?
Keywords: Nanomaterials; Biomaterials; Advanced wound healing therapies; Current regulatory perspective; ASTM; American Society for Testing and Materials; CQA; critical quality attributes; ECM; extracellular matrix; EGF; epidermal growth factor; EMA; European medic
Old meets new: Combination of PLA and RDRP to obtain sophisticated macromolecular architectures
Keywords: AGET; activator generated by electron transfer; AlpGP; 1,2:3,4-Di-O-isopropylidene-6-O-acryloyl-α-d-galactopyranose; ATRP; atom-transfer radical polymerization; BEMP; 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine; BGMA; cis
From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications
Keywords: 0-D; zero dimensional; 1-D; one dimensional; 2-D; two dimensional; 3-D; three dimensional; anti-EpCAM; anti-epithelial cell adhesion molecule; bFGF; basic fibroblast growth factor; BSHFs; bead-on-string heterostructured fibers; CFU; Colony-Forming Units;
Natural polyphenols as versatile platforms for material engineering and surface functionalization
Keywords: ABTS+; 2,2â²-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid); AgNPs; silver nanoparticles; AgrTA; tannic acid-functionalized agarose; ALP; alkaline phosphatase; A. niger; Aspergillus niger; APTES; 3-aminopropyltriethoxysilane; AuNPs; gold nanoparticles;
Smart polymersomes and hydrogels from polypeptide-based polymer systems through α-amino acid N-carboxyanhydride ring-opening polymerization. From chemistry to biomedical applications
Keywords: ADSCs; adipose derived stem cells; AFM; atomic force microscopy; AG; l/dl-allylglycine; AIBN; 2,2â²-azobisisobutyronitrile; Ala; alanine; ATR-FTIR; attenuated total reflectance Fourier transform infrared spectroscopy; ATRP; atom transfer radical polymeri
Clinical PaperSolution blow spun polymer: A novel preclinical surgical sealant for bowel anastomoses
Keywords: Surgical sealant; Bowel anastomosis; BSP; solution blow spun polymer; PEG; polyethylene glycol; PLGA; poly(lactic-co-glycolic acid); H&E; hematoxylin and eosin;
Preparation and physicochemical characterization of T-OA PLGA microspheres
Keywords: T-OA; PLGA; Microspheres; Solubility; Release;
Efficacious cellular codelivery of doxorubicin and EGFP siRNA mediated by the composition of PLGA and PEI protected gold nanoparticles
Keywords: Codelivery; Doxorubicin; siRNA; PLGA; PEI gold nanoparticles;
Feasibility of drug delivery to the eye's posterior segment by topical instillation of PLGA nanoparticles
Keywords: PLGA; Nanoparticles; Topical instillation; Retina; Surface modification;
Iontophoretic transdermal delivery using chitosan-coated PLGA nanoparticles for positively charged drugs
Keywords: Donepezil hydrochloride; Transdermal administration; Iontophoresis; Coumarin; Rhodamine; poly(dl-lactide-co-glycolide); PLGA; Positively charged nanoparticles; Hydrophilic drug;
Development and validation of a rapid reversed-phase HPLC method for the quantification of monoclonal antibody bevacizumab from polyester-based nanoparticles
Keywords: AE; association efficiency; DL; drug loading; TFA; trifluoroacetic acid; LOD; detection limit; LOQ; quantification limit; mAb; monoclonal antibody; PLGA; poly (lactic-co-glycolic acid); PVA; poly(vinyl alcohol); VEGF-A; vascular endothelial growth factor
cmRNA/lipoplex encapsulation in PLGA microspheres enables transfection via calcium phosphate cement (CPC)/PLGA composites
Keywords: PLGA; Transcript therapy; Microparticles; Calcium phosphate cements; Lipoplexes; Bone substitute materials;
The control of beads diameter of bead-on-string electrospun nanofibers and the corresponding release behaviors of embedded drugs
Keywords: BD; bead diameter; BL/BD; bead length/bead diameter; TCH; tetracycline hydrochloride; PLGA; poly (lactic-co-glycolic acid); SEM; scanning electron microscopy; Bead-on-string nanofiber; Electrospinning; Bead diameter; Micro-particle drug; Release profile;
Preparation, physicochemical characterization and anti-fungal evaluation of the Nystatin-loaded Eudragit RS100/PLGA nanoparticles
Keywords: Nanoparticles; Nystatin; C. albicans; PLGA; Eudragit RS100;
PLGA nano/microparticles loaded with cresyl violet as a tracer for drug delivery: Characterization and in-situ hyperspectral fluorescence and 2-photon localization
Keywords: PLGA; Hyperspectral fluorescence; Two-photon microscopy; Biodistribution; Cresyl violet;
Development of a single-dose recombinant CAMP factor entrapping poly(lactide-co-glycolide) microspheres-based vaccine against Streptococcus agalactiae
Keywords: BCA; bicinchoninic acid; CAMP; Christie-Atkins-Munch-Petersen; ELISA; enzyme-linked immune-sorbent assay; IMI; intramammary infection; MS; microspheres; PCR; polymerase chain reaction; PLGA; poly(lactic-co-glycolic acid); PLGA-CAMP; PLGA MS encapsulat
Design of parenteral MNP-loaded PLGA nanoparticles by a low-energy emulsification approach as theragnostic platforms for intravenous or intratumoral administration
Keywords: Nano-emulsion templating; Low-energy emulsification; Iron oxide nanoparticle-loaded polymeric nanoparticles; PLGA;
“Curcumin-loaded Poly (d, l-lactide-co-glycolide) nanovesicles induce antinociceptive effects and reduce pronociceptive cytokine and BDNF release in spinal cord after acute administration in mice”
Keywords: PLGA; Poly (d,l-lactide-co-glycolide) vesicles; CUR; Curcumin, (1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione); PLGA-CUR; Poly (d,l-lactide-co-glycolide) curcumin-loaded vesicles; PWL; Paw Withdrawal Latency; NSAIDs; Nonsteroidal Anti-Inflam
Development and evaluation of Desvenlafaxine loaded PLGA-chitosan nanoparticles for brain delivery
Keywords: PLGA; Nanoparticles; Desvenlafaxine; Depression; Brain; Intranasal; CNS; central nervous system; FST; forced swim test; BBB; blood brain barrier; BSF; blood-cerebrospinal fluid barrier; i.n.; intranasal; 5 HT; 5-hydroxytryptamine; HCl; hydrochloric acid;
Co-utilization of a TLR5 agonist and nano-formulation of HIV-1 vaccine candidate leads to increased vaccine immunogenicity and decreased immunogenic dose: A preliminary study
Keywords: Nanovaccine; HIV-P24-Nef; PLGA; FliC; TLR-5;
Printing particles: A high-throughput technique for the production of uniform, bioresorbable polymer microparticles and encapsulation of therapeutic peptides
Keywords: Ink-jet; Printing; Microparticle; Encapsulation; Peptide; PLGA;
Nano-precipitated curcumin loaded particles: effect of carrier size and drug complexation with (2-hydroxypropyl)-β-cyclodextrin on their biological performances
Keywords: Curcumin; Nanoparticles; PLGA; Poloxamers; Mesothelioma; Cyclodextrin;
Freeze-casting for PLGA/carbonated apatite composite scaffolds: Structure and properties
Keywords: Porous scaffolds; Composite; PLGA; Carbonated apatite; Bone engineering;
Preparation and investigation of P28GST-loaded PLGA microparticles for immunomodulation of experimental colitis
Keywords: PLGA; Microparticles; Preventive colitis treatment; Protein delivery; P28GST;
Gene expression profiling of chicken cecal tonsils and ileum following oral exposure to soluble and PLGA-encapsulated CpG ODN, and lysate of Campylobacter jejuni
Keywords: Chicken; Cecal tonsils; Ileum; Campylobacter; CpG ODN; Nanoparticle; PLGA; Cytokines; Antimicrobial peptides;
Research paperInfluence of different stabilizers on the encapsulation of desmopressin acetate into PLGA nanoparticles
Keywords: Desmopressin; PLGA; Nanoparticle; HPLC; Mass spectrometry; Encapsulation; Surfactant; Adsorption; TGA; thermogravimetric analysis; DLS; Dynamic Light Scattering; LDA; Laser-Doppler-Anemometry; PLGA; polylactic-co-glycolic acid; NP; nanoparticles; HPLC; Hi
Research paperAmplified CPEs enhancement of chorioamnion membrane mass transport by encapsulation in nano-sized PLGA particles
Keywords: Chemical penetration enhancers; Ultrasound; Nanoparticles; Chorioamnion; PLGA; Mass transport enhancement;
Original ArticleChitosan-modified PLGA nanoparticles tagged with 5TR1 aptamer for in vivo tumor-targeted drug delivery
Keywords: Epirubicin; PLGA; 5TR1aptamer; Chitosan;
Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors
Keywords: miR; micro RNA; miRi; micro RNA inhibitor; pac; paclitaxel; ER; estrogen receptor; PR; progesterone receptor; HER2/neu; epidermal growth factor receptor 2; TNBC; triple-negative breast cancer; PLGA; poly(d,l-lactide-co-glycolide); PEG; poly(ethylene-glyco
NECL1 coated PLGA as favorable conduits for repair of injured peripheral nerve
Keywords: Peripheral nerve injuries; NECL1; PLGA; Sciatic nerve; Nerve regeneration;
Zero order controlled release delivery of cholecalciferol from injectable biodegradable microsphere: In-vitro characterization and in-vivo pharmacokinetic studies
Keywords: Cholecalciferol; PLGA; Microspheres; Stabilizer; Tocopherol succinate; Vitamin D;
Sustained release ophthalmic dexamethasone: In vitro in vivo correlations derived from the PK-Eye
Keywords: Ocular drug delivery; Pharmacokinetics; In vitro in vivo correlations; Sustained release; PLGA;