
Improvement of the skeletal and dental hypophosphatasia phenotype in Alpl−/− mice by administration of soluble (non-targeted) chimeric alkaline phosphatase
Keywords: PLP، پرییدکسال فسفات; ChimAP, chimeric alkaline phosphatase; PL, pyridoxal; PLP, pyridoxal phosphate; TNAP, tissue-nonspecific alkaline phosphatase; PDL, periodontal ligament; PPi, inorganic pyrophosphateEnzyme replacement; Hypophosphatasia; Rickets; Osteomalacia; Craniosynost