کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2053408 1074276 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Direct interaction and cooperative role of tumor suppressor p16 with band 3 (AE1)
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
Direct interaction and cooperative role of tumor suppressor p16 with band 3 (AE1)
چکیده انگلیسی

By using the C-terminal 112-residue of band 3 to screen the K562 cDNA library, we find that the p16 interacts with band 3, which was confirmed both in yeast and in mammalian cells. Functional experiments show that p16 facilitates the movement of band 3 to plasma membrane with increased anion transport activity in 293t cells. Moreover, expression of endogenous p16 in 293t cells was increased at 24 and 36 h after transfection with band 3. Our findings provide a novel regulation pathway for both band 3 and p16.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 579, Issue 10, 11 April 2005, Pages 2105–2110
نویسندگان
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