The F-box protein β-TrCP promotes ubiquitination of TRF1 and regulates the ALT-associated PML bodies formation in U2OS cells
Keywords: TRF1; β-TrCP; Ubiquitination; PML;
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Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence
Keywords: OIS; oncogene-induced senescence; MEF; mouse embryonic fibroblast; ERK; extracellular signal-regulated kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphatidylinositol 3-kinase; pRb; retinoblastoma tumor suppressor protein; SA-β-Gal; sene
The Bcl-2/Bcl-xL inhibitor BH3I-2â² affects the dynamics and subcellular localization of sumoylated proteins
Keywords: SUMO; Bcl-2; Bcl-2 inhibitor; PML; Nuclear bodies; Proteasome;
Death-domain associated protein-6 (DAXX) mediated apoptosis in hantavirus infection is counter-balanced by activation of interferon-stimulated nuclear transcription factors
Keywords: DAXX; Hantavirus; HUVEC; ISG-20; PML; Sp100; SUMO;
The translation initiation factor 3 subunit eIF3K interacts with PML and associates with PML nuclear bodies
Keywords: PML; eIF3K; Nuclear structure; Light microscopy; Yeast two-hybrid;
DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication
Keywords: 5â² ppp; 5â² triphosphate; AIM2; Absent In Melanoma 2; ARE; AU-rich element; CARD; Caspase Activation and Recruitment Domains; CDN; cyclic dinucleotide; cGAMP; cyclic-GMP-AMP; cGAS; cGAMP Synthase; CRM1; Chromosome Maintenance Region 1; CstF; Cleavage S
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress
Keywords: a.a.; amino acid; ATF; activating transcription factor; Bcl-2; B-cell lymphoma 2; Bcl-Xl; B-cell lymphoma-extra large; BH3; Bcl-2 homology 3; BI-1; Bax inhibitor-1; BiP; immunoglobulin heavy chain-binding protein; CHOP; C/EBP-homologous protein; CSQ; cals
A woman with ataxia, nystagmus and headache
Keywords: HAART; highly active antiretroviral therapy; HIVE; HIV-associated encephalopathy; IRIS; immune reconstitution inflammatory syndrome; JCV; John Cunningham virus; PML; progressive multifocal leukoencephalopathy; TE; toxoplasma encephalitis;
Ultra-wide band microwave image reconstruction for early breast cancer detection by norm constrained capon beamforming
Keywords: UWB; Breast cancer detection; FDTD; PML; NCCB
Downregulation of tumor suppressor gene PML in uterine cervical carcinogenesis: Impact of human papillomavirus infection (HPV)
Keywords: PML; Cervical cancer; HPV
Leveraging Administrative Data to Monitor Rituximab Use in 2875 Patients at 42 Freestanding Children's Hospitals across the United States
Keywords: ICD-9-CM; International Classification of Diseases, Ninth Revision, Clinical Modification; PHIS; Pediatric Health Information System; PML; Progressive multifocal leukoencephalopathy; SLE; Systemic lupus erythematosus;
Validation of PML-based models for the evaluation of anchor dissipation in MEMS resonators
Keywords: Anchor losses; PML; MEMS; Resonators; Wave dissipation
Degradation of CREB-binding protein and modulation of type I interferon induction by the zinc finger motif of the porcine reproductive and respiratory syndrome virus nsp1α subunit
Keywords: Arterivirus; Nidovirus; Immune evasion; Interferon modulation; Non-structural protein; PRRS; nsp1; CREB binding protein; CBP; PML; Zinc finger; Interferon antagonist
When will α-HCH disappear from the western Arctic Ocean?
Keywords: α-HCH; Contaminants; Arctic; Polar Mixed Layer; PML; Pacific Mode Layer; Beaufort Sea
Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
Keywords: Signal transducer and activator of transcription 1; IFN-γ; progressive multifocal leukoencephalopathy; Histoplasma capsulatum; Coccidioides immitis; thrush; CMC; Chronic mucocutaneous candidiasis; CSF; Cerebrospinal fluid; CT; Computed tomography; DMA; M
Multi-site analytical validation of an assay to detect anti-JCV antibodies in human serum and plasma
Keywords: JCV; JC virus; PML; progressive multifocal leukoencephalopathy; ELISA; enzyme-linked immunosorbent assay; VLP; virus-like particles; nOD; normalized optical density; QC; quality controls; PC; positive control; NC; negative control; Anti-JC virus (JCV) ant
Antibody to α4 integrin suppresses natural killer cells infiltration in central nervous system in experimental autoimmune encephalomyelitis
Keywords: Natalizumab; VLA-4; Multiple sclerosis; EAE; PML; Flow cytometry;
Monoclonal Antibodies for Therapeutic Use: Specific Characteristics of Clinical Development, Evaluation by the Agencies, and Long-term Monitoring of Safety
Keywords: monoclonal antibodies; clinical trials, phase I; clinical trials, phase II; clinical trials, phase IV; ADCC; antibody dependent cellular cytotoxicity; (ex-)Afssaps; ex-Agence française de sécurité sanitaire des produits de santé (at present french Nat
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
Keywords: AD; Alzheimer's disease; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor; aPKC; atypical protein kinase C; APP; amyloid-β precursor protein; ATG; AuTophaGy-related; BDNF; brain-derived neurotrophic factor; C/EBP; C
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma
Keywords: PML; p73; YAP; Apoptosis; Glioblastoma
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death
Keywords: PD; Parkinson disease; DAergic; dopaminergic; DA; dopamine; 6-OHDA; 6-hydroxydopamine; ROS; reactive oxygen species; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-dichlorodihydrofluorescein diacetate acetyl ester; PML; promyelocytic leukemia; NAC; N-acetyl
Solution of coupled acoustic-elastic wave propagation problems with anelastic attenuation using automatic hp-adaptivity
Keywords: Borehole acoustic logging; Wave propagation; Linear elasticity; Coupled problems; Hp-adaptive finite elements; PML;
Efficient solution of Maxwell’s equations for geometries with repeating patterns by an exchange of discretization directions in the aperiodic Fourier modal method
Keywords: Aperiodic Fourier modal method; AFMM-CFF; Rigorous coupled-wave analysis; RCWA; Electromagnetic scattering; Perfectly matched layer; PML; Computational complexity; Alternative discretization
A study of clinical profile of HIV positive patients with neurological manifestations
Keywords: ADC; Aids dementia complex; ATT; anti-tuberculous therapy; AKD; Alka K. Deshpande; ART; anti-retroviral therapy; AIDS; acquired immunodeficiency syndrome; AIDP; acute inflammatory demyelinating neuropathy; CCM; cryptococcal meningitis; CSF; cerebrospinal
A Crohn's Disease Patient Who Does Not Respond to Infliximab: What Is Next?
Keywords: ATI; antibodies to infliximab; CD; Crohn's disease; CDAI; Crohn's Disease Activity Index; CMV; cytomegalovirus; CRP; C-reactive protein; PML; progressive multifocal leukoencephalopathy; TNF; tumor necrosis factor;
Intrinsic cellular defense mechanisms targeting human cytomegalovirus
Keywords: HCMV; Nuclear domain 10; PML nuclear bodies; PML; Sp100; hDaxx; ATRX; Antiviral defense; Intrinsic immunity
Impact of cellular senescence signature on ageing research
Keywords: Age-related disease; Biomarkers; DNA damage; Low-grade inflammation; PML; SAHFs; Secretory phenotype; Senescence; Telomeres
Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients
Keywords: Multiple sclerosis; Immunomodulation; PML; Natalizumab; Cytokines; Autoimmunity
Saddle-Shape Annuloplasty Increases Mitral Leaflet Coaptation After Repair for Flail Posterior Leaflet
Keywords: AA; anterior annulus; AC; anterior commissure; AH; annular height; AHWCR; annular height to commissural width ratio; AML; anterior mitral leaflet; AoV; aortic valve; CW; commissural width; LA; left atrium; LV; left ventricle; LVOT; left ventricular outflo
Study of early events during herpes simplex virus type 1 infection by confocal microscopy
Keywords: FITC; fluorescein isothiocyanate; ICP0; infected cell protein 0; ND10; Nuclear Domain 10; PBS; phosphate buffered saline; PML; promyelocytic leukaemia (protein); Laser scanning confocal microscopy; Herpes simplex virus type 1;
Nuclear body formation and PML body remodeling by the human cytomegalovirus protein UL35
Keywords: CMV; Cytomegalovirus; PML; Promyelocytic leukemia; pp71; UL35; UL35a; Nuclear bodies;
Impact of Preoperative Anterior Leaflet Tethering on the Recurrence of Ischemic Mitral Regurgitation and the Lack of Left Ventricular Reverse Remodeling after Restrictive Annuloplasty
Keywords: Mitral valve; Myocardial infarction; Coronary artery bypass grafts; αâ²; Anterior mitral leaflet tethering angle; ALPM; Anterolateral papillary muscle; AML; Anterior mitral leaflet; βâ²; Posterior mitral leaflet tethering angle; CIMR; Chronic ischemic
Harnessing dendritic cells in inflammatory skin diseases
Keywords: SALT; skin-associated lymphoid tissue; DCs; dendritic cells; AD; atopic dermatitis; CHS; contact hypersensitivity; DDCs; dermal DCs; MHC; major histocompatibility complex; pDCs; plasmacytoid DCs; TLR; toll-like receptor; SLE; systemic lupus erythematousus
Human polyomavirus JC small regulatory agnoprotein forms highly stable dimers and oligomers: Implications for their roles in agnoprotein function
Keywords: JC virus; SV40; BKV; PML; Agnoprotein; Stable dimer; Oligomer; Transcription; Replication
Control of nuclear HIPK2 localization and function by a SUMO interaction motif
Keywords: SIM; SUMO; HIPK2; Nuclear bodies; PML;
Regulation of nucleocytoplasmic trafficking of viral proteins: An integral role in pathogenesis?
Keywords: BPV; bovine papillomavirus; BRAP2; BRCA1-associated protein 2; CAV; chicken anaemia virus; CBP; CREB binding protein; Cdk; cyclin dependent kinase; CK1; protein kinase CK1; CK2; protein kinase CK2; Crm1; chromosome region maintenance protein 1; CTD; C-ter
An optimal 25-point finite difference scheme for the Helmholtz equation with PML
Keywords: Helmholtz equation; PML; 25-point finite difference scheme; Numerical dispersion;
Unmasking of PML by HAART: Unusual clinical features and the role of IRIS
Keywords: HIV; PML; HAART; IRIS; Immune reconstitution
Addiction to protein kinase CK2: A common denominator of diverse cancer cells?
Keywords: ALCL; anaplastic large cell lymphoma; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; CML; chronic myeloid leukemia; MDR; multi-drug resistance; MM; multiple myeloma; NF-kB; nuclear factor-kB; PDK1; 3â²-phosphoinositide-dependent kinase-1
Modulation of the Zac1's transactivation and coactivation functions via PML and Daxx within distinct subcellular localizations
Keywords: Zac1; PML; Daxx; Coactivation; Subcellular localization;
Differential relocation and stability of PML-body components during productive human cytomegalovirus infection: Detailed characterization by live-cell imaging
Keywords: HCMV; IE1-72K; ND10; PML; Sp100; hDaxx; STAT1; STAT2; Condensed chromatin; Live-cell microscopy
Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers
Keywords: Mechanism of action; Rheumatoid arthritis; Systemic lupus erythematosus; Sjögren's syndrome; Biomarker; B cell-targeting drugs; ACPA; anti-citrullinated peptide antibody; ACR; American College of Rheumatology; APRIL; a proliferation-inducing ligand; BCMA
Immunohistochemical Surrogates for Genetic Alterations of CCDN1, PML, ALK, and NPM1 Genes in Lymphomas and Acute Myeloid Leukemia
Keywords: Monoclonal antibodies; CCND1; PML; ALK; Nucleophosmin; Lymphoma; Leukemia; Immunohistochemistry
Anatomy of the mitral subvalvular apparatus
Keywords: papillary muscle; tendinous cords; chordae tendineae; tendinous chords; mitral valve; strut chordae; rough zone; clear zone; basal zone; mitral leaflet; bicuspid valve; AML; anterior mitral leaflet; ISPM; inferoseptal papillary muscle; LVOT; left ventricu
Numerical analyses of splice losses of photonic crystal fibers
Keywords: 02.70.Dh; 42.25.Bs; 42.81.Bm; 42.81.Dp; 42.81.GsSplice loss; Rotation loss; PCF; FEM; PML
Detection of BK, JC, WU, or KI polyomaviruses in faecal, urine, blood, cerebrospinal fluid and respiratory samples
Keywords: JCV; JC polyomavirus; BKV; BK polyomavirus; PML; progressive multifocal leukoencephalopathy; CSF; cerebrospinal fluid; WUV; WU polyomavirus; KIV; KI polyomavirus; RSV; respiratory syncytial virus; INF A & B; influenza virus A and B; PIV 1,2,3; parainfluen
Cyclin D1 expression and its possible regulation in chewing tobacco mediated oral squamous cell carcinoma progression
Keywords: Cyclin D1; Normal oral mucosa; PML; OSCC; Progression
The role of polyomaviruses in human disease
Keywords: Polyomavirus; JCV; BKV; PML; Polyomavirus nephropathy; KI; WU; MCV
JC Virus: An oncogenic virus in animals and humans?
Keywords: JCV; JC virus; PML; Progressive Multifocal Leukoencephalopathy; T Ag; large tumor antigen; t Ag; small tumor antigen; JC virus; Polyomavirus; Cancer; DNA tumor virus; PML;