Keywords: جهش نقطه; CRC; colorectal cancer; CTCs; circulating tumor cells; cfDNA; cell-free DNA; HMs; histon modifications; LOH; loss of heterozygosity; miRNAs; microRNAs; MSI; microsatellite instability; Colorectal cancer; Blood-based biomarkers; Liquid biopsy; Circulating
مقالات ISI جهش نقطه (ترجمه نشده)
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Keywords: جهش نقطه; Two-state proteins; Unfolding rates; Point mutations; Multiple regression technique; Machine learning; Amino acid properties
Functional effects of substitutions I92T and V95A in actin-binding period 3 of tropomyosin
Keywords: جهش نقطه; DCM; dilated cardiomyopathy; HCM; hypertrophic cardiomyopathy; Tpm1.1; homodimer of Tpm1.1 isoform; Tpm2.2; homodimer of Tpm2.2; His-Tpm2.2; homodimer of His-tagged Tm2.2; Tpm1.1/Tpm2.2; heterodimer of two tropomyosin isoforms; Tpm1.1-I92T/Tpm1.1; Tpm1.1-
Molecular typing of a novel canine parvovirus type 2a mutant circulating in Italy
Keywords: جهش نقطه; Dogs; Canine parvovirus; Protoparvovirus; Molecular characterization; Sequence analysis; Point mutations;
Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists
Keywords: جهش نقطه; α7 nAChR; Point mutations; α-Conotoxins; α-Cobratoxin; Sequence difference; Ligand binding domain; Xenopus oocytes;
Genotoxicity assessment of piperitenone oxide: An in vitro and in silico evaluation
Keywords: جهش نقطه; Rotundifolone; Flavouring agent; Mentha spp.; Genotoxicity assessment; Point mutations; In silico prediction; Chromosomal damage;
Technologies for analysis of circulating tumour DNA: Progress and promise
Keywords: جهش نقطه; Circulating tumour DNA; Polymerase chain reaction; Point mutations; Sequencing; Epigenetic changes;
Identification of structural elements involved in fine-tuning of the transport activity of the rice ammonium transporter OsAMT1;3
Keywords: جهش نقطه; OsAMT1;3; Functional modulation; Point mutations; Substrate permeability;
Genotoxicity assessment of some cosmetic and food additives
Keywords: جهش نقطه; Genotoxicity; Lilial®; α-Hexylcinnamaldheide; Point mutations; Micronuclei; Comet assay;
Genetyczne podstawy syntezy cukrowych antygenów grupowych krwi
Keywords: جهش نقطه; cukrowe antygeny grupowe krwi; ABO; P1PK; NOR; punktowe mutacje; Carbohydrate blood-group antigens; ABO; P1PK; NOR; point mutations;
Monitoring of carbamate and organophosphate resistance levels in Nilaparvata lugens based on bioassay and quantitative sequencing
Keywords: جهش نقطه; Resistance monitoring; Quantitative sequencing; Nilaparvata lugens; Acetylcholinesterase; Point mutations;
Real-time PCR for Helicobacter pylori quantification and detection of clarithromycin resistance in gastric tissue from patients with gastrointestinal disorders
Keywords: جهش نقطه; Helicobacter pylori; Bacterial load; 23S rRNA; Point mutations; Real-time PCR
The effect of point mutations on structure and mechanical properties of collagen-like fibril: A molecular dynamics study
Keywords: جهش نقطه; Collagen fibril; Molecular dynamics simulations; Point mutations; Osteogenesis Imperfecta; Mechanical properties;
Evaluation of chemically modified carrier proteins for developing monoclonal antibodies against a clinically relevant mutation of cKIT
Keywords: جهش نقطه; Chemical modification; Protein carriers; Point mutations; Monoclonal antibodies;
Abiotic stress leads to somatic and heritable changes in homologous recombination frequency, point mutation frequency and microsatellite stability in Arabidopsis plants
Keywords: جهش نقطه; Arabidopsis thaliana; Homologous recombination; Point mutations; Microsatellite stability; Abiotic stress; Heat; Drought; Cold; Flood; UVC; Transgenerational changes;
Characterisation and management of Phalaris paradoxa resistant to ACCase-inhibitors
Keywords: جهش نقطه; Hood canary grass; Herbicide resistance; Acetyl-CoA carboxylase; Target-site resistance mechanism; Point mutations; dCAPS;
Agonist-dependent effects of mutations in the sphingosine-1-phosphate type 1 receptor
Keywords: جهش نقطه; G protein-coupled receptor; Sphingosine-1-phosphate (S1P); S1P1 receptor model; FTY720-P; SEW2871; Point mutations
Emerging importance of ALK in neuroblastoma
Keywords: جهش نقطه; Neuroblastoma; ALK; Tyrosine kinase receptor; Targeted therapy; Crizotinib; Drug resistance; Point mutations; Small molecule inhibitors; Combination treatment
Hybridisation thermodynamic parameters allow accurate detection of point mutations with DNA microarrays
Keywords: جهش نقطه; DNA microarray; Thermodynamics; Nearest neighbour model; Point mutations
Increased activity of enzymatic transacylation of acrylates through rational design of lipases
Keywords: جهش نقطه; Lipase; CALB; Point mutations; Kinetics; Proficiency
Differential inhibition sensitivities of MET mutants to the small molecule inhibitor SU11274
Keywords: جهش نقطه; Receptor tyrosine kinases; MET; Point mutations; SU11274; Drug resistance;
Acaricide resistance mechanisms in the two-spotted spider mite Tetranychus urticae and other important Acari: A review
Keywords: جهش نقطه; Tetranychus; Varroa; Rhipicephalus; Sodium channel; Acetylcholinesterase; Cytochrome b; QoI; Point mutations; Resistance mechanisms; Mitochondrial heteroplasmy; Bifenazate; METI; Pyrethroid
Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations
Keywords: جهش نقطه; Streptococcus pyogenes; Quinolone resistance; Epidemiology; Antimicrobial resistance mechanisms; Point mutations
Structural basis of the selectivity of the β2-adrenergic receptor for fluorinated catecholamines
Keywords: جهش نقطه; G protein-coupledreceptors; Adrenergic agonists; Fluorine substitution; Catecholamines; Receptor selectivities; Point mutations; Receptor modeling
Genotyping of K-ras codons 12 and 13 mutations in colorectal cancer by capillary electrophoresis
Keywords: جهش نقطه; Universal primer-PCR; SSCP-CE; Point mutations; K-ras gene
MLPA analysis/complete sequencing of the DMD gene in a group of Bulgarian Duchenne/Becker muscular dystrophy patients
Keywords: جهش نقطه; Duchenne/Becker muscular dystrophy; DMD gene; Dystrophin; MLPA; Deletions; Duplications; Point mutations
Development and evaluation of a reverse dot blot assay for the simultaneous detection of six common Chinese G6PD mutations and one polymorphism
Keywords: جهش نقطه; Glucose-6-phosphate dehydrogenase deficiency (G6PD); Reverse dot blot (RDB); Multiplex polymerase chain reaction (M-PCR); Point mutations
Importance of Investigating Somatic and Germline Mutations in Hemophilia A: A Preliminary Study from All India Institute of Medical Sciences, India
Keywords: جهش نقطه; Somatic mosaicism; Hemophilia A; Allele Specific PCR; Germ-line; Point mutations
Detection of four β-thalassemia point mutations in Iranians using a PCR-ELISA genotyping system
Keywords: جهش نقطه; PCR-ELISA; Point mutations; β-Thalassemia; ARMS
Detection of mutant protein in complex biological samples: Glucocerebrosidase mutations in Gaucher’s disease
Keywords: جهش نقطه; Gaucher’s disease; Glucocerebrosidase; Point mutations; Surface-enhanced laser desorption/ionization (SELDI); Matrix-assisted laser desorption/ionization (MALDI); Immunoproteomics
The role of host PrP in Transmissible Spongiform Encephalopathies
Keywords: جهش نقطه; PrP; Prions; Gene targeting; Transgenic mice; Point mutations; Infection
Protein radial distribution function (P-RDF) and Bayesian-Regularized Genetic Neural Networks for modeling protein conformational stability: Chymotrypsin inhibitor 2 mutants
Keywords: جهش نقطه; Protein stability prediction; Point mutations; Bayesian regularization; Artificial neural networks; Genetic algorithm
Genetic variations of the Plasmodium vivax dihydropteroate synthase gene
Keywords: جهش نقطه; Malaria; Plasmodium vivax; Dihydropteroate synthase; Polymorphism; Point mutations
Resistance pattern and point mutations of insensitive acetylcholinesterase in a carbamate-resistant strain of housefly (Musca domestica)
Keywords: جهش نقطه; Insensitive acetylcholinesterase; Insecticide resistance; Point mutations; Musca domestica
Plasmodium vivax dihydrofolate reductase point mutations from the Indian subcontinent
Keywords: جهش نقطه; Malaria; Plasmodium vivax; Dihydrofolate reductase; Antifolate; Pyrimethamine; Point mutations; Drug resistance
Target site insensitivity and mutational analysis of acetylcholinesterase from a carbofuran-resistant population of Colorado potato beetle, Leptinotarsa decemlineata (Say)
Keywords: جهش نقطه; Colorado potato beetle; Carbofuran resistance; AChE insensitivity; Point mutations; Negative cross-resistance; Negative cross-insensitivity
Biochemical basis for retinol deficiency induced by the I41N and G75D mutations in human plasma retinol-binding protein
Keywords: جهش نقطه; Retinol-binding protein; Point mutations; Retinol delivery; Vitamin A deficiency; Transthyretin; Phospholipid membranes;
Contribution of de novo point mutations to the overall mutational burden in mitochondrial DNA of adult rats
Keywords: جهش نقطه; Mitochondrial DNA; Point mutations; Aging; Rats; Brain; Muscle;
Mitochondrial DNA mutations in RRF of healthy subjects of different age
Keywords: جهش نقطه; Human skeletal muscle; Ragged red fibers; mtDNA; Point mutations; Aging;
Activation of ionotropic receptors and thermodynamics of binding
Keywords: جهش نقطه; AChBP; acetylcholine binding protein; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole; ÎCp; heat capacity change; ÎH; change in enthalpy; ÎS; change in entropy; ÎG; change in free energy; GABAA; A-type γ-aminobutyric acid; MPPB; 1-methyl-5-phenyl-5-pro