Keywords: سم شناسی پیش بینی کننده; Exposure-dose-response; Risk assessment; Predictive toxicology; Biodissolution; Extrapolation modelling;
مقالات ISI سم شناسی پیش بینی کننده (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: سم شناسی پیش بینی کننده; Computational biology; Developmental neurotoxicity; Pesticide; Pyriproxyfen; Predictive toxicology; Systems biology; Toxicity testing;
Keywords: سم شناسی پیش بینی کننده; Toxicogenomics; Drug development; Drug discovery; Drug safety; Predictive toxicology;
Keywords: سم شناسی پیش بینی کننده; In silico; In silico toxicology; Computational toxicology; Predictive toxicology; QSAR; Expert alert; Expert review;
Keywords: سم شناسی پیش بینی کننده; Nanomaterials; Toxicogenomics; Predictive toxicology; Bi-clustering;
Keywords: سم شناسی پیش بینی کننده; 3-Oxobutanamide derivatives; Isolated mitochondria; Human lymphocytes; Predictive toxicology;
Keywords: سم شناسی پیش بینی کننده; Carcinogenicity; Predictive toxicology; Structure-activity; Alternative testing; Nongenotoxic carcinogens
Keywords: سم شناسی پیش بینی کننده; Data quality; Microtox; Confidence; QSAR; Predictive toxicology; Conflicting data;
Keywords: سم شناسی پیش بینی کننده; (Q)SAR; Read across; Chemical grouping; In silico toxicology; Predictive toxicology; Risk assessment; Uncertainties; Food; Incident management;
Keywords: سم شناسی پیش بینی کننده; Stem cell-derived cardiomyocytes; Jaspamide; Cyclodepsipeptide; In vitro alternatives; Predictive toxicology; Cardiotoxicity;
Keywords: سم شناسی پیش بینی کننده; Drug-induced liver injury; Three-dimensional liver co-cultures; Cytochrome P450; Drug safety assessment; Idiosyncratic toxicity; Predictive toxicology;
Environmental risk assessment of selected organic chemicals based on TOC test and QSAR estimation models
Keywords: سم شناسی پیش بینی کننده; QSAR; Risk assessment; Predictive toxicology; TOC; Physicochemical property;
Cardiac safety evaluation in zebrafish and in silico ADME prediction of cephalosporins with an aminothiazoyl ring at the C-7 position
Keywords: سم شناسی پیش بینی کننده; Predictive toxicology; Embryo; Biomarkers; Zebrafish; Cardiac toxicity;
Autoencoder Predicting Estrogenic Chemical Substances (APECS): An improved approach for screening potentially estrogenic chemicals using in vitro assays and deep learning
Keywords: سم شناسی پیش بینی کننده; Deep learning; Autoencoder; Endocrine disruptor; Estrogenic; Predictive toxicology; Computational toxicology; High throughput screening;
Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity
Keywords: سم شناسی پیش بینی کننده; Angiogenic inhibition; Predictive toxicology; Zebrafish;
ReviewPolysaccharide matrices used in 3D in vitro cell culture systems
Keywords: سم شناسی پیش بینی کننده; ECM; Scaffolds; Hydrogels; Glycosaminoglycan; Proteoglycan; Predictive toxicology;
CORAL: Binary classifications (active/inactive) for drug-induced liver injury
Keywords: سم شناسی پیش بینی کننده; QSAR; Drug-induced liver injury; Monte Carlo method; Predictive toxicology; Risk assessment;
Cytotoxicity towards CCO cells of imidazolium ionic liquids with functionalized side chains: Preliminary QSTR modeling using regression and classification based approaches
Keywords: سم شناسی پیش بینی کننده; Imidazolium ionic liquids; CCO cell line; In vitro toxicity; Quantitative structure–toxicity relationship; Predictive toxicology
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
Keywords: سم شناسی پیش بینی کننده; 1-NP; 1-naphthol; APBS; adaptive Poisson-Boltzmann solver; DBI; Davies-Bouldin index; DMSO; dimethylsulfoxide; EC; extracellular buffer; GAFF; generalized amber force field; hERG; human ether-á-go-go-related K+ ion channel; IC; intracellular buffer;
The application of 3D cell models to support drug safety assessment: Opportunities & challenges
Keywords: سم شناسی پیش بینی کننده; Drug safety assessment; Predictive toxicology; In vitro toxicology; Mechanistic toxicology; 3R
Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity
Keywords: سم شناسی پیش بینی کننده; iPSC; induced pluripotent stem cell; BMC; benchmark concentration; DMSO; dimethyl sulfoxide; AUC; area under the curve; EC50; effective concentration at 50% of the maximum response; iPSC; Calcium flux; Cardiotoxicity; hERG; Phenotypic screening; Predictiv
A rat retinal damage model predicts for potential clinical visual disturbances induced by Hsp90 inhibitors
Keywords: سم شناسی پیش بینی کننده; Hsp90 inhibitors; Visual impairment; Retinal degeneration; Drug safety assessment; Predictive toxicology; Rodent model;
IARC Classes 1 and 2 carcinogens are successfully identified by an alternative strategy that detects DNA-reactivity and cell transformation ability of chemicals
Keywords: سم شناسی پیش بینی کننده; Predictive toxicology; Cancer; Mutagenicity; Regulation; Structure–Activity
Towards model governance in predictive toxicology
Keywords: سم شناسی پیش بینی کننده; Model governance; Data governance; Predictive toxicology; Information representation; Knowledge management; Quality assessment
Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: Application to acetaminophen injury
Keywords: سم شناسی پیش بینی کننده; Microfluidic biochip; PDMS; liver tissue engineering; predictive toxicology; acetaminophen; transcriptomic; proteomic; metabolomic; biomarkers identification
The embryonic stem cell test combined with toxicogenomics as an alternative testing model for the assessment of developmental toxicity
Keywords: سم شناسی پیش بینی کننده; Alternative test; Embryonic stem cell test; Predictive toxicology; Toxicogenomics; Transcriptomics
EU Framework 6 Project: Predictive Toxicology (PredTox)—overview and outcome
Keywords: سم شناسی پیش بینی کننده; Toxicogenomics; Proteomic; Metabolomics; Predictive toxicology; FP6; Consortium
Application of connectivity mapping in predictive toxicology based on gene-expression similarity
Keywords: سم شناسی پیش بینی کننده; Connectivity mapping; Query gene signature; Reference gene-expression profile; Predictive toxicology
Improved 3D-QSAR analyzes for the predictive toxicology of polybrominated diphenyl ethers with CoMFA/CoMSIA and DFT
Keywords: سم شناسی پیش بینی کننده; Polybrominated diphenyl ethers; QSARs; CoMFA; CoMSIA; DFT; Predictive toxicology
Using explanations for determining carcinogenecity in chemical compounds
Keywords: سم شناسی پیش بینی کننده; Lazy learning; Explanations; Partial domain models; Feature terms; Lazy induction of descriptions; Predictive toxicology
Databases applicable to quantitative hazard/risk assessment—Towards a predictive systems toxicology
Keywords: سم شناسی پیش بینی کننده; Data integration; Toxicogenomics; Predictive toxicology; Carcinogenicity; Mode-of-action; Genotoxicity
Creation of a digital slide and tissue microarray resource from a multi-institutional predictive toxicology study in the rat: An initial report from the PredTox group
Keywords: سم شناسی پیش بینی کننده; Tissue microarray; Digital images; Slide scanning; Toxicology; Database; Preclinical; Biomarker; Predictive toxicology; PredTox
Computer-aided drug discovery and development (CADDD): In silico-chemico-biological approach
Keywords: سم شناسی پیش بینی کننده; Drug discovery; Drug development; Molecular modeling; Virtual screening; Computational modeling; In silico drug design; QSAR/QSPR; Predictive toxicology
Understanding mechanisms of toxicity: Insights from drug discovery research
Keywords: سم شناسی پیش بینی کننده; High-throughput screening; High-content screening; In vitro toxicology; Mechanism of toxicity; Systems toxicology; Predictive toxicology
Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models
Keywords: سم شناسی پیش بینی کننده; Carcinogenicity; Discriminant analysis; In silico; Predictive toxicology; Topological descriptors; QSAR; E-state; Chemoinformatics; Discriminant analysis; Consensus prediction
Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products
Keywords: سم شناسی پیش بینی کننده; Genotoxicity; Carcinogenicity; In silico screening; Predictive toxicology; Drug development; OECD principles
Toxicogenomic analysis methods for predictive toxicology
Keywords: سم شناسی پیش بینی کننده; Predictive toxicology; Toxicogenomics; Gene expression; Review
Biophotonic imaging in HO-1.luc transgenic mice: Real-time demonstration of gender-specific chloroform induced renal toxicity
Keywords: سم شناسی پیش بینی کننده; Chloroform; Haem oxygenase-1; Oxidative stress; Transgenic mouse promoter-reporter models; Biophotonics; Predictive toxicology;
In silico screening of chemicals for bacterial mutagenicity using electrotopological E-state indices and MDL QSAR software
Keywords: سم شناسی پیش بینی کننده; QSAR; E-state indices; Electrotopological; Mutagenicity; In silico screening; Predictive toxicology; Drug development; Salmonella; Setubal principles;