Keywords: پروژورمون تبدیل; GLP-1; glucagon-like peptide 1; GLP-2; glucagon-like peptide 2; GLP-2R; GLP-2 receptor; HFD; high fat diet; PC; prohormone convertase; POMC; proopiomelanocortin; GLP-2; L-type enteroendocrine cells; Food intake; Obesity; Insulin resistance;
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IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies
Keywords: پروژورمون تبدیل; 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r
Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population
Keywords: پروژورمون تبدیل; AFDS; Amish Family Diabetes Study; CPE; carboxypeptidase E; ExAC; Exome Aggregation Consortium; ESP; Exome Sequencing Project; GERP; genomic evolutionary rate profiling; IGT; impaired glucose tolerance; MAF; minor allele frequency; NGT; normal glucose tol
C-terminal amidation of PACAP-38 and PACAP-27 is dispensable for biological activity at the PAC1 receptor
Keywords: پروژورمون تبدیل; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CPE; carboxypeptidase E/H; CRE; cyclic AMP response element; GPCR; G protein-coupled receptor; NPY; neuropeptide Y; NS-1; Neuroscreen-1; PACAP; pituitary adenylate cyclase-activating polypeptide; PAC1; PACAP
Reprogramming of enteroendocrine K cells to pancreatic β-cells through the combined expression of Nkx6.1 and Neurogenin3, and reaggregation in suspension culture
Keywords: پروژورمون تبدیل; Adv; adenovirus; DAPI; 4â²,6â²-diamidino-2-phenylindole; DAPT; N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester; DMEM; Dulbecco's Modified Eagle's Medium; GFP; green fluorescent protein; GIP; glucose-dependent insulinotropic polypep
Morphine treatment selectively regulates expression of rat pituitary POMC and the prohormone convertases PC1/3 and PC2
Keywords: پروژورمون تبدیل; Post-translational processing; Opioids; Endorphin; Prohormone convertase; Pituitary; Drug addiction;
Angiogenesis in the intermediate lobe of the pituitary gland alters its structure and function
Keywords: پروژورمون تبدیل; PD; pars distalis; PI; pars intermedia; VEGF; vascular endothelial growth factor; ME; median eminence; α-MSH; alpha-melanophore-stimulating hormone; PC; prohormone convertase; POMC; proopiomelanocortin; GFP; green fluorescent protein; MS222; 3-aminobenzo
Impairment of Proinsulin Processing in β-Cells Exposed to Saturated Free Fatty Acid Is Dependent on Uncoupling Protein-2 Expression
Keywords: پروژورمون تبدیل; insulin; lipotoxicity; prohormone convertase; uncoupling protein 2insuline; lipotoxicité; prohormone convertase; protéine découplante 2
Ferric ions inhibit proteolytic processing of progastrin
Keywords: پروژورمون تبدیل; CRC, colorectal carcinoma; Ggly, glycine-extended gastrin; PC1, prohormone convertase 1Ferric; Gastrin; Iron; Processing; Progastrin; Prohormone convertase
Processing of chromogranins/secretogranin in patients with diabetic retinopathy
Keywords: پروژورمون تبدیل; A1AT; alpha1-antitrypsin; CgA; chromogranin A; CgB; chromogranin B; DR; diabetic retinopathy; DV; diabetic vitreous; HbA1C; glycated haemoglobin; HRB; hematoretinal barrier; nanoLC-MS/MS; nano-liquid chromatography-mass spectrometry/mass spectrometry; N
Hypothalamic proopiomelanocortin processing and the regulation of energy balance
Keywords: پروژورمون تبدیل; Proopiomelanocortin; POMC; α-MSH; Prohormone convertase; Carboxypeptidase E; Obesity
The avian proglucagon system
Keywords: پروژورمون تبدیل; G-protein-coupled receptor; Glucagon; Glucagon-like peptide-1; Glucagon-like peptide-2; Hormone; Oxyntomodulin; Proglucagon; Prohormone convertase
The proprotein convertase amontillado (amon) is required during Drosophila pupal development
Keywords: پروژورمون تبدیل; Prohormone convertase; PC2; Pupal development; Metamorphosis; Ecdysis
Differential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: Implications for understanding the “switch” to opiate addiction
Keywords: پروژورمون تبدیل; post-translational processing; opiates; endorphin; TRH; hypothalamus; drug addiction; AHiAL; anterolateral nucleus of the amygdala; ATF-1; activation transcription factor-1; CRE; cyclic AMP-response element; CREM; cAMP response element modulator; CRH; cor
Expression of proglucagon and proglucagon-derived peptide hormone receptor genes in the chicken
Keywords: پروژورمون تبدیل; Chicken; Gene expression; Glucagon; Glucagon-like peptide-1; Glucagon-like peptide-2; Proglucagon; Prohormone convertase; Receptor
Processing and trafficking of a prohormone convertase 2 active site mutant
Keywords: پروژورمون تبدیل; CMK; decanoyl-Arg-Val-Lys-Arg-chloromethylketone; ER; endoplasmic reticulum; PCs; proprotein convertases; TGN; trans-Golgi network; Active site mutant; Processing; Prohormone convertase; Sorting; Zymogen;
Proprotein convertases 1 and 2 (PC1 and PC2) are expressed in neurally differentiated rat bone marrow stromal stem cells (BMSCs)
Keywords: پروژورمون تبدیل; BMSCs; PC1; PC2; Neural differentiation; Gene expression; Prohormone convertase
The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway
Keywords: پروژورمون تبدیل; Prohormone convertase; Enzyme; Sorting; Lipid raft; Transmembrane protein
Endogenous C-terminal fragments of beta-amyloid precursor protein from Xenopus laevis skin exudate
Keywords: پروژورمون تبدیل; APP C-terminal fragments; β- γ- ε-secretases; Caspase activity; Endopeptidase; Prohormone convertase; Xenopus laevis;
Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity
Keywords: پروژورمون تبدیل; Furin; BACE; TGN; Prohormone convertase; Alzheimer’s; SEAP; Alkaline phosphatase; NSAIDs
Immunohistochemical expression and colocalization of somatostatin, carboxypeptidase-E and prohormone convertases 1 and 2 in rat brain
Keywords: پروژورمون تبدیل; carboxypeptidase-E; prosomatostatin; prohormone convertase; regulatory secretory pathway; sorting receptor; CPE; carboxypeptidase-E; NGS; normal goat serum; PC1; prohormone convertase 1; PC2; prohormone convertase 2; PSST; prosomatostatin; RSP; regulated