دانلود مقالات ISI درباره فرمول پروتئین + ترجمه فارسی

Demonstrating the Stability of Albinterferon Alfa-2b in the Presence of Silicone Oil

Keywords: فرمول پروتئین; freeze drying/lyophilization; analytical biochemistry; analytical ultracentrifugation; protein delivery; protein structure; stability; circular dichroism; FTIR; protein aggregation; protein formulation;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

High Throughput Formulation Screening for Global Aggregation Behaviors of Three Monoclonal Antibodies

Keywords: فرمول پروتئین; protein aggregation; stability; Fluorescence spectroscopy; Light-scattering; protein formulation; high throughput technologies; monoclonal antibody;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations

Keywords: فرمول پروتئین; monoclonal antibody; stability; high concentration; protein aggregation; thermal analysis; design of experiment; high throughput technologies; protein formulation;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Nonnative Aggregation of an IgG1 Antibody in Acidic Conditions, Part 2: Nucleation and Growth Kinetics with Competing Growth Mechanisms

Keywords: فرمول پروتئین; biotechnology; kinetics; protein aggregation; precipitation; protein formulation;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Interactions of formulation excipients with proteins in solution and in the dried state

Keywords: فرمول پروتئین; Protein formulation; Excipients; Stability; Attraction pressure; Preferential interaction; Excluded volume; Amorphous glass; Solution; Dry

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2011 سفارش ترجمه

Protein stabilization by cyclodextrins in the liquid and dried state

Keywords: فرمول پروتئین; Protein; Cyclodextrin; HPβCD; Protein aggregation; Lyophilization; Liquid formulation; Protein stabilization; Non-ionic surfactant; Monoclonal antibody; Protein formulation

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2011 سفارش ترجمه

Impact of Product-Related Factors on Immunogenicity of Biotherapeutics

Keywords: فرمول پروتئین; biotechnology; protein formulation; protein aggregation; chemical stability; immunogenicity; antidrug antibodies;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2011 سفارش ترجمه

Implementation of an FTIR calibration curve for fast and objective determination of changes in protein secondary structure during formulation development

Keywords: فرمول پروتئین; FTIR; Secondary structure; Protein formulation; Circular dichroism; Multivariate data analysis; Calibration curve

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Adsorption Behavior of a Surfactant and a Monoclonal Antibody to Sterilizing-Grade Filters

Keywords: فرمول پروتئین; biotechnology; proteins; protein formulation; surfactants; polysorbate; Tween; filtration; adsorption;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Relevant shaking stress conditions for antibody preformulation development

Keywords: فرمول پروتئین; Antibody formulation; Shaking stress; Stress conditions; Physical stability; Mechanical stress; Protein aggregation; Protein formulation; Size exclusion chromatography; Turbidity; Preformulation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis, characterization and assessment of suitability of trehalose fatty acid esters as alternatives for polysorbates in protein formulation

Keywords: فرمول پروتئین; Nonionic surfactants; Trehalose esters; Surfactant characterization; Protein formulation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products

Keywords: فرمول پروتئین; biophysical models; protein aggregation; protein formulation; high‐performance/pressure liquid chromatography (HPLC); analytical ultracentrifugation; analytical biochemistry; physical stability;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Comparative Evaluation of Disodium Edetate and Diethylenetriaminepentaacetic Acid as Iron Chelators to Prevent Metal -Catalyzed Destabilization of a Therapeutic Monoclonal Antibody

Keywords: فرمول پروتئین; Protein aggregation; oxidation; deamidation; fragmentation; chelator; monoclonal antibody; protein structure; binding; stability; protein formulation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Understanding and Modulating Opalescence and Viscosity in a Monoclonal Antibody Formulation

Keywords: فرمول پروتئین; light scattering; protein delivery; protein formulation; viscosity; physical characterization;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Stabilization of Lysozyme by Benzyl Alcohol: Surface Tension and Thermodynamic Parameters

Keywords: فرمول پروتئین; protein aggregation; protein formulation; circular dichroism; stabilization; performulation; protein folding/refolding becomes an essential step during the formulation development of multi-dose protein products;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Buffer-Dependent Fragmentation of a Humanized Full-Length Monoclonal Antibody

Keywords: فرمول پروتئین; biotechnology; chemical stability; formulation; protein folding/refolding; protein formulation; proteins;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Formulation and Immunogenicity of a Potential Multivalent Type III Secretion System-Based Protein Vaccine

Keywords: فرمول پروتئین; protein formulation; stability; vaccine adjuvants; protein aggregation; fluorescence spectroscopy; adsorption; deamidation; tip proteins; needle proteins; immunogenicity;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Inhibition of Agitation‐Induced Aggregation of an IgG‐Antibody by Hydroxypropyl‐β‐Cyclodextrin

Keywords: فرمول پروتئین; calorimetry (DSC); cyclodextrins; excipients; stability; formulation; FTIR; proteins; physicochemical properties; protein aggregation; protein formulation;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Quantification and Characterization of Subvisible Proteinaceous Particles in Opalescent mAb Formulations Using Micro-Flow Imaging

Keywords: فرمول پروتئین; image analysis; particle size; protein formulation; physical stability; preformulation;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Factors Affecting the Viscosity in High Concentration Solutions of Different Monoclonal Antibodies

Keywords: فرمول پروتئین; proteins; protein formulation; viscosity; light-scattering; formulation;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2010 سفارش ترجمه

Multi-variate approach to global protein aggregation behavior and kinetics: Effects of pH, NaCl, and temperature for α-chymotrypsinogen A

Keywords: فرمول پروتئین; protein aggregation; stability; protein formulation;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2010 سفارش ترجمه

The Effects of Substituted Cyclodextrins on the Colloidal and Conformational Stability of Selected Proteins

Keywords: فرمول پروتئین; cyclodextrins; protein aggregation; formulation; structure; stability; protein structure; protein formulation; biotechnology;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

An Industry Perspective on the Monitoring of Subvisible Particles as a Quality Attribute for Protein Therapeutics

Keywords: فرمول پروتئین; biotechnology; particle size; protein aggregation; protein formulation; immunology;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2010 سفارش ترجمه

Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: Stability after freeze‐drying

Keywords: فرمول پروتئین; freeze‐drying/lyophilization; collapse; monoclonal antibody; L‐lactic dehydrogenase; protein aggregation; protein formulation; specific surface area; calorimetry (DSC); solid‐state stability; FTIR;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2010 سفارش ترجمه

Surface Activity of a Monoclonal Antibody

Keywords: فرمول پروتئین; protein formulation; proteins; protein aggregation; surfactants; stabilization;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The effect of sucrose hydrolysis on the stability of protein therapeutics during accelerated formulation studies

Keywords: فرمول پروتئین; physical stability; protein formulation; mass spectrometry; protein; aggregation; high-performance/pressure liquid chromatography (HPLC); kinetics; chemical stability;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

The Impact of Protein Concentration on Mannitol and Sodium Chloride Crystallinity and Polymorphism Upon Lyophilization

Keywords: فرمول پروتئین; lyophilization; polymorphism; excipients; freeze-drying; protein formulation; X-ray powder diffractometry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Biophysical Characterization and Formulation of F1-V, a Recombinant Plague Antigen

Keywords: فرمول پروتئین; F1-V; plague; vaccine; biotechnology; protein aggregation; protein formulation; circular dichroism; fluorescence spectroscopy; light scattering;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Biochemical Assessment of Erythropoietin Products From Asia Versus US Epoetin alfa Manufactured by Amgen

Keywords: فرمول پروتئین; biotechnology; capillary electrophoresis; chemical stability; electrophoresis; glycoprotein; glycosylation; physical characterization; protein aggregation; protein formulation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

The Role of Covalent Dimerization on the Physical and Chemical Stability of the EC1 Domain of Human E-Cadherin

Keywords: فرمول پروتئین; protein formulation; physical stability; protein aggregation; protein structure; biotechnology; circular dichroism; fluorescence spectroscopy; formulation; preformulation; proteins;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Quantitation of protein particles in parenteral solutions using micro-flow imaging

Keywords: فرمول پروتئین; analytical chemistry; proteins; excipients; protein formulation; image analysis; imaging methods; injectables; light-scattering; particle size; protein aggregation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Insulin Loaded PLGA Microspheres: Effect of Zinc Salts on Encapsulation, Release, and Stability

Keywords: فرمول پروتئین; poly(lactic/glycolic) acid (PLGA or PLA); electrophoresis; microspheres; protein formulation; infrared spectroscopy;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Liquid high concentration IgG1 antibody formulations by precipitation

Keywords: فرمول پروتئین; crystallization; excipients; precipitation; protein formulation; stability; protein aggregation

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Mixing Properties of Lyophilized Protein Systems: A Spectroscopic and Calorimetric Study

Keywords: فرمول پروتئین; freeze drying/lyophilization; mixing; protein formulation; proteins; spectroscopy; calorimetry (DSC); thermal analysis; thermodynamics

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Light-induced aggregation of type I soluble tumor necrosis factor receptor

Keywords: فرمول پروتئین; absorption spectroscopy; biotechnology; circular dichroism; protein aggregation; protein formulation; protein structure; proteins; stability; UV/Vis spectroscopy; high-performance/pressure liquid chromatography (HPLC)

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Immunogenicity of aggregates of recombinant human growth hormone in mouse models

Keywords: فرمول پروتئین; immunology; protein aggregation; protein formulation; protein; structure; transgenics; protein folding/refolding

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanisms of protein stabilization in the solid state

Keywords: فرمول پروتئین; solid-state stability; freeze drying/lyophilization; physical characterization; protein formulation; relaxation time

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2009 سفارش ترجمه

Protein aggregation: Pathways, induction factors and analysis

Keywords: فرمول پروتئین; protein aggregation; protein analysis; protein formulation; molecular weight determination; particle sizing; size exclusion chromatography; analytical ultra-centrifugation; light scattering; SDS–PAGE; orthogonal methods

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2009 سفارش ترجمه

Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

Keywords: فرمول پروتئین; protein aggregation; biophysical models; physical stability; kinetics; protein formulation;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2009 سفارش ترجمه

High throughput methods to characterize protein permeation and release

Keywords: فرمول پروتئین; Protein formulation; Drug release; Permeability; Hirudin; High throughput screening

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

pH dependent effect of glycosylation on protein stability

Keywords: فرمول پروتئین; Protein formulation; Thermal/storage stability; Unfolding; Aggregation/precipitation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Strategies to maximize the encapsulation efficiency of phenylalanine ammonia lyase in microcapsules

Keywords: فرمول پروتئین; Microcapsules; Phenylalanine ammonia lyase; Phenylketonuria; Encapsulation efficiency; Catalytic activity; Protein formulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Development of an in situ forming PLGA drug delivery system: I. Characterization of a non-aqueous protein precipitation

Keywords: فرمول پروتئین; Biodegradable polymers; Protein delivery; Injectables; Polymeric drug delivery systems; Stability; Microencapsulation; Precipitation; Protein aggregation; Protein formulation; FTIR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells

Keywords: فرمول پروتئین; Silk fibroin; Scaffolds; Drug delivery; Protein formulation; Growth factors; Tissue engineering; Cartilage; IGF-I; Human mesenchymal stem cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Physical Stabilization of Norwalk Virus‐Like Particles*

Keywords: فرمول پروتئین; physical stability; preformulation; protein aggregation; excipients; protein formulation; fluorescence spectroscopy; circular dichroism; calorimetry (DSC); vaccines;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Behaviour of Polysorbate 20 During Dialysis, Concentration and Filtration Using Membrane Separation Techniques

Keywords: فرمول پروتئین; biotechnology; proteins; protein formulation; surfactants; polysorbate; tween; micelles; critical micelle concentration; filtration; ultrafiltration;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Protection of aluminum hydroxide during lyophilisation as an adjuvant for freeze-dried vaccines

Keywords: فرمول پروتئین; Aluminum hydroxide; Vaccine adjuvants; Stabilisation; Protein formulation; Freeze drying/lyophilisation; Formulation development

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of Solution Conditions, Processing Parameters, and Container Materials on Aggregation of a Monoclonal Antibody during Freeze-Thawing

Keywords: فرمول پروتئین; monoclonal antibodies; freeze-thaw; protein aggregation; protein stability; protein formulation;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Phosphatidylserine Containing Liposomes Reduce Immunogenicity of Recombinant Human Factor VIII (rFVIII) in a Murine Model of Hemophilia A*

Keywords: فرمول پروتئین; hemophilia A; recombinant FVIII; immunogenicity; inhibitor antibodies; phosphatidylserine liposomes; protein delivery; protein formulation; lipids; immunology;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Preformulation Studies of Clostridium difficile Toxoids A and B

Keywords: فرمول پروتئین; vaccines; protein formulation; protein aggregation; protein structure; proteins; stability; UV/vis spectroscopy; biotechnology; excipients;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه