Keywords: تثبیت پروتئین; Bile salts; Bovine serum albumin; Chemical denaturation; Thermal denaturation; Tryptophan fluorescence; Protein stabilization;
مقالات ISI تثبیت پروتئین (ترجمه نشده)
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Keywords: تثبیت پروتئین; Electrostatic energy; FMN; FBP; Protein stabilization; Molecular dynamics simulation;
Keywords: تثبیت پروتئین; Human interferon gamma; Protein stabilization; Buffer optimization; Thermofluor assay; Differential scanning calorimetry;
Keywords: تثبیت پروتئین; Osmolytes; Methylamines; Protein stabilization; Accessible surface area; Gibbs free energy;
Keywords: تثبیت پروتئین; Protein aggregation; Anti-aggregation agent; Trehalose phenylalaninate; Protein stabilization; Bovine serum albumin; Molecular docking;
Keywords: تثبیت پروتئین; Osmolytes; Methylamines; Protein stabilization; Accessible surface area; Gibbs free energy
Keywords: تثبیت پروتئین; Freely available; Protein stabilization; Sugar glass; Droplet drying; Diffusion; Mathematical model;
Keywords: تثبیت پروتئین; Chemical denaturation; Thermal denaturation; Protein stabilization; Ovalbumin; Simulated honey sugar cocktail;
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration
Keywords: تثبیت پروتئین; Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon
Natural deep eutectic solvents as a storage medium for human interferon-α2: a green and improved strategy for room-temperature biologics
Keywords: تثبیت پروتئین; Green solvent; Protein stabilization; Room temperature storage; Natural deep eutectic solvent; Designer solvent;
FoldX as Protein Engineering Tool: Better Than Random Based Approaches?
Keywords: تثبیت پروتئین; FoldX; Fold-X; Thermostability; Protein stabilization; Protein engineering; Enzyme engineering;
Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase
Keywords: تثبیت پروتئین; Isomalt; Freeze-drying; Protein stabilization; Lactate dehydrogenase; Sucrose;
Short communicationFreeze-dried EchiTAb+ICP antivenom formulated with sucrose is more resistant to thermal stress than the liquid formulation stabilized with sorbitol
Keywords: تثبیت پروتئین; Snake; Antivenom; EchiTAb+ICP; Freeze-drying; Protein stabilization; Sorbitol; Sucrose;
α-Chymotrypsin in water-ethanol mixtures: Effect of preferential interactions
Keywords: تثبیت پروتئین; Protein hydration; Preferential solvation and hydration; Protein stabilization; Bovine pancreatic α-chymotrypsin; Ethanol;
Addition of Pullulan to Trehalose Glasses Improves the Stability of β-Galactosidase at High Moisture Conditions
Keywords: تثبیت پروتئین; BSA; bovine serum albumin; DSC; differential scanning calorimetry; DVS; dynamic vapor sorption; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; RH; relative humidity; Tg; glass transition temperature; Tgâ²; glass transition temperature of the
Improving potency and metabolic stability by introducing an alkenyl linker to pyridine-based histone deacetylase inhibitors for orally available RUNX3 modulators
Keywords: تثبیت پروتئین; RUNX3; RUNX3 acetylation; HDAC inhibition; Epigenetic control; Protein stabilization;
Hydrolysis and oxidation of racemic esters into prochiral ketones catalyzed by a consortium of immobilized enzymes
Keywords: تثبیت پروتئین; System biocatalysis; Lipase; Alcohol dehydrogenase; Multi-enzyme systems; Protein stabilization
Retinoic acid regulates Schwann cell migration via NEDD9 induction by transcriptional and post-translational mechanisms
Keywords: تثبیت پروتئین; Schwann cell; Migration; NEDD9; Retinoic acid; Peripheral nerve regeneration; Protein stabilization;
Bridging the bridge-Stabilization of CalB against H2O2 and its application in epoxidation reactions
Keywords: تثبیت پروتئین; Intramolecular disulfide conjugation; Protein stabilization; Immobilization; Candida antarctica lipase B; Epoxidation;
Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization
Keywords: تثبیت پروتئین; KCTD5; BTB domain; E3 ubiquitin ligase; MCM7; ZNF711; Protein stabilization; AAV-2; adeno-associated virus type 2; BTB; bric-a-brac, tramtrak and broad complex; FAM193B; family with sequence similarity 193, member B; FOXO1; forkhead box O1; KCTD; Potassiu
Arginine inhibits aggregation of α-lactalbumin but also decreases its stability: Calorimetric, spectroscopic, and molecular dynamics studies
Keywords: تثبیت پروتئین; Protein stabilization; Isothermal titration calorimetry; Differential scanning calorimetry; Radial distribution function; Hydrogen bond dynamics
Xyloglucan-based diblock co-oligomer: Synthesis, self-assembly and steric stabilization of proteins
Keywords: تثبیت پروتئین; Xyloglucan oligosaccharides; Click reaction; Amphiphilic block co-oligomer; Self-assembly; Micelles; Protein stabilization;
Effect of NaCl on the conformational stability of the thermophilic γ-glutamyltranspeptidase from Geobacillus thermodenitrificans: Implication for globular protein halotolerance
Keywords: تثبیت پروتئین; Protein stabilization; Circular dichroism; NaCl; Fluorescence; Gamma-glutamyl transferase; Gamma-glutamyl transpeptidase;
Stabilization of bovine insulin against agitation-induced aggregation using RNA aptamers
Keywords: تثبیت پروتئین; Aptamer; Diabetes; Fibrillation; Insulin; Protein stabilization
Method development for proteome stabilization in human saliva
Keywords: تثبیت پروتئین; Human saliva; Proteome; Protein stabilization; Immunoassay; Clinical application
Stabilization of a highly active but unstable alcohol dehydrogenase from yeast using immobilization and post-immobilization techniques
Keywords: تثبیت پروتئین; Protein stabilization; Post-immobilization techniques; Alcohol dehydrogenase; Multimeric enzymes; Asymmetric chemistry
Stabilization and encapsulation of recombinant human erythropoietin into PLGA microspheres using human serum albumin as a stabilizer
Keywords: تثبیت پروتئین; Recombinant human erythropoietin; Protein stabilization; Microspheres; Solid-in-oil-in-water (s/o/w) emulsion method; Human serum albumin
Protein and DNA destabilization by osmolytes: The other side of the coin
Keywords: تثبیت پروتئین; Osmolyte; Preferential hydration; Protein stabilization; Protein destabilization; Protein folding
Protein stabilization by cyclodextrins in the liquid and dried state
Keywords: تثبیت پروتئین; Protein; Cyclodextrin; HPβCD; Protein aggregation; Lyophilization; Liquid formulation; Protein stabilization; Non-ionic surfactant; Monoclonal antibody; Protein formulation
Boron stabilizes peroxide mediated changes in the structure of heme proteins
Keywords: تثبیت پروتئین; Boron; Protein stabilization; Peroxide; Cytochrome c; Metmyoglobin
Water Sorption Glass Transition Protein-Stabilizing Behavior of an Amorphous Sucrose Matrix Combined With Various Materials
Keywords: تثبیت پروتئین; amorphous; sugar; additives; water sorption; glass transition; protein stabilization;
Biophysical characterization of recombinant proteins: A key to higher structural genomics success
Keywords: تثبیت پروتئین; Thermodenaturation; Protein stabilization; Ligand binding; Peptide array; Chemical probes;
A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases
Keywords: تثبیت پروتئین; Bacterial glutathione S-transferase; Ochrobactrum anthropi; Hydrogen-bond network; Protein stabilization; Circular dichroism
The use of Group 3 LEA proteins as fusion partners in facilitating recombinant expression of recalcitrant proteins in E. coli
Keywords: تثبیت پروتئین; LEA proteins; Recombinant protein expression; Protein stabilization
Role of benzyl alcohol in the prevention of heat-induced aggregation and inactivation of hen egg white lysozyme
Keywords: تثبیت پروتئین; Lysozyme; Benzyl alcohol; Multi-dose formulation; Protein stabilization; Circular dichroism;
Stable sugar-based protein formulations by supercritical fluid drying
Keywords: تثبیت پروتئین; Supercritical fluid drying; Protein stabilization; FTIR; Protein structure; Sucrose; Trehalose; Lysozyme
Interaction of selected cosolvents with bovine α-lactalbumin
Keywords: تثبیت پروتئین; αLA, α-lactalbumin; βLG, β-lactoglobulinα-Lactalbumin; Densimetry; Protein stabilization; Sorbitol; Glycerol; Sucrose; Thermal transition temperature (apparent Tm)
Drying-Induced Variations in Physico-Chemical Properties of Amorphous Pharmaceuticals and Their Impact on Stability (I): Stability of a Monoclonal Antibody*
Keywords: تثبیت پروتئین; composition heterogeneity; electron spectroscopy for chemical analysis; glass dynamics; incoherent elastic neutron scattering; molecular mobility; protein stabilization; protein secondary structure; structural relaxation time; specific surface area; surfa
Glycol chitosan as a stabilizer for protein encapsulated into poly(lactide-co-glycolide) microparticle
Keywords: تثبیت پروتئین; Glycol chitosan; Lysozyme; Protein stabilization; Poly(lactide-co-glycolide) degradation; Microparticle
Maintenance of vascular endothelial growth factor and potentially other therapeutic proteins bioactivity during a photo-initiated free radical cross-linking reaction forming biodegradable elastomers
Keywords: تثبیت پروتئین; Photo-cross-linking; Vascular endothelial growth factor; Protein stabilization; Protein bioactivity
Improvement of wine crossflow microfiltration by a new hybrid process
Keywords: تثبیت پروتئین; Wine clarification; Crossflow microfiltration; Fouling; Adsorption; Protein stabilization
Protein complexed with chondroitin sulfate in poly(lactide-co-glycolide) microspheres
Keywords: تثبیت پروتئین; Chondroitin sulfate; Ionic complex; Protein stabilization; Poly(lactide-co-glycolide) microsphere
The Challenge of Drying Method Selection for Protein Pharmaceuticals: Product Quality Implications
Keywords: تثبیت پروتئین; atomization; electron spectroscopy for chemical analysis; evaporation; freeze drying; glass dynamics; molecular mobility; protein stabilization; spray drying; spray freeze drying; surface analysis; vacuum drying;
Soluble expression, purification, and stabilization of a pro-apoptotic human protein, CARP
Keywords: تثبیت پروتئین; CARP; Escherichia coli; Soluble expression; Protein purification; Protein stabilization
Different mechanisms of protein immobilization on glutaraldehyde activated supports: Effect of support activation and immobilization conditions
Keywords: تثبیت پروتئین; Glutaraldehyde; Hetero-functional supports; Physical adsorption of proteins; Covalent immobilization of proteins; Protein stabilization
Folding studies of two hydrostatic pressure sensitive proteins
Keywords: تثبیت پروتئین; High pressure; Unfolding/folding of protein; Pressure jump; Protein stabilization
Compatible solutes as protectants for zymogens against proteolysis
Keywords: تثبیت پروتئین; Protein folding; Serine proteases; Zymogens; Proteolytic activation; Compatible solutes; Protein stabilization
Effect of cyclodextrins on α-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation
Keywords: تثبیت پروتئین; cyclodextrins; microspheres; protein aggregation; protein stabilization; solid-in-oil-in-water (s/o/w) encapsulation procedure;
Presence of peptide inhibitors in rattlesnake venoms and their effects on endogenous metalloproteases
Keywords: تثبیت پروتئین; Autolytic degradation; Coelution; Enzymes; Protein stabilization; Venom gland; Venom storage;
Compatible solute effects on thermostability of glutamine synthetase and aspartate transcarbamoylase from Methanococcus jannaschii
Keywords: تثبیت پروتئین; Methanococcus jannaschii; Glutamine synthetase; Aspartate transcarbamoylase; α-glutamate; β-glutamate; Protein stabilization;