Keywords: پروتئین تیروزین فسفاتاز 1B; PTP1B; protein tyrosine phosphatase 1B; CNS; central nervous system; HFD; high fat diet; NPY; neuropeptide Y; AMPK; 5' AMP-activated protein kinase; BAT; brown adipose tissue; AF; albiflorin; hAMSCs; human adipose tissue-derived mesenchymal stem cells; PP
مقالات ISI پروتئین تیروزین فسفاتاز 1B (ترجمه نشده)
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Keywords: پروتئین تیروزین فسفاتاز 1B; Ala; alanine; Arg; arginine; CR; caloric restriction; GH; growth hormone; GHR; growth hormone receptor; GHRH; growth hormone-releasing hormone; IGF-1; insulin-like growth factor 1; IL; interleukin; IKKα/β; inhibitor of nuclear factor kappa-B kinase α/Î
Keywords: پروتئین تیروزین فسفاتاز 1B; AC; anthocyanidins; GIP; gastric inhibitory polypeptide; GLP-1; glucagon-like peptide-1; GTT; glucose tolerance test; HFD; high fat diet; 4-HNE; 4-hydroxynonenal; IKK; IκB kinase; IRS1; insulin receptor substrate-1; ITT; insulin tolerance test; JNK; c-ju
Keywords: پروتئین تیروزین فسفاتاز 1B; Akt2; RAC-β serine/threonine-protein kinase; AR; aldose reductase; Bcl-2; B-cell lymphoma 2; CFL1; cofilin 1;; cMDH1; cytosolic NAD-dependent malate dehydrogenase 1; CTSK; cathepsin K; Cu-Zn SOD; Cu/Zn superoxide dismutase; DHAR2; dehydroascorbate reduct
Keywords: پروتئین تیروزین فسفاتاز 1B; AT; adipose tissue; LPS; lipopolysaccharide; OSA; obstructive sleep apnea; PPARγ; peroxisome proliferator-activated receptor-gamma; PTP-1B; protein tyrosine phosphatase 1B; Obstructive sleep apnea adipose tissue; Insulin resistance; Macrophage; Epigeneti
Keywords: پروتئین تیروزین فسفاتاز 1B; ROS; reactive oxygen species; Prx; peroxiredoxin; PTP1B; protein tyrosine phosphatase 1B; PTEN; phosphatase and tensin homologue; MEFs; mouse embryonic fibroblasts; Nac; N-acetyl cysteine; GTT; glucose tolerance test; GLUT4; glucose transporter type 4; PT
Keywords: پروتئین تیروزین فسفاتاز 1B; Alzheimer's disease; Diabetes; Insulin resistance; Inflammation; Gangliosides; mTOR; PTP1B; AβOs; Aβ peptide oligomers; AD; Alzheimer's disease; APP; amyloid precursor protein; AICD; amyloid precursor protein intracellular domain; BDNF; brain-derived ne
Keywords: پروتئین تیروزین فسفاتاز 1B; βcR; beta common receptor; cEpo; carbamylated erythropoietin; eNOS; endothelial nitric oxide synthase; Epo; erythropoietin; EpoR; erythropoietin receptor; FBS; fetal bovine serum; NAC; N acetyl-cysteine; L-NMMA; NG-methyl-l-arginine acetate; NO; nitric o
Keywords: پروتئین تیروزین فسفاتاز 1B; CSP; chemical shift perturbation; PTP; protein tyrosine phosphatase; PTP1B; protein tyrosine phosphatase 1B; VHR; Vaccinia H1-related phosphatase; BB30; benzofuran-based small molecule; pNPP; p-nitrophenylphosphate; SASA; solvent-accessible surface areas;
Keywords: پروتئین تیروزین فسفاتاز 1B; â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: پروتئین تیروزین فسفاتاز 1B; SDF-1; stromal cell-derived factor 1; PAD; peripheral arterial disease; GPx; glutathione peroxidase; TAK1; transforming growth factor-B-activated-kinase 1; PTP1B; protein tyrosine phosphatase 1B; EDRF; endothelial-derived relaxing factor (EDRF); BH4; tetr
Keywords: پروتئین تیروزین فسفاتاز 1B; SCFAs; short-chain fatty acids; LDLR; low-density lipoprotein receptor; InsR; insulin receptor; AMPK; AMP-activated protein kinase; PCSK9; proprotein convertase subtilisin kexin 9; PTP1B; protein tyrosine phosphatase 1B; BBR; berberine; TC; total choleste
Keywords: پروتئین تیروزین فسفاتاز 1B; Noninvasive indices; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Simple steatosis; Treatment; ABCA1; ATP-binding cassette transporter subfamily A, member A1; ALT; alanine transaminase; AST; aspartate transaminase; AMPK; 5â² adenosine
Keywords: پروتئین تیروزین فسفاتاز 1B; 5/15-LOX; 5/15-lipoxygenase; AChE; acetylcholinesterase; AUF-MS; affinity-ultrafiltration mass spectrometry; BFA; bound fraction analysis; COX-2; cyclooxygenase-2; GST; glutathione S-transferase; HPLC-DAD-MS; high performance liquid chromatography-dio
Keywords: پروتئین تیروزین فسفاتاز 1B; GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: پروتئین تیروزین فسفاتاز 1B; Vanadyl alginate polysaccharides; Vanadyl alginate oligosaccharides; Antioxidant activity; Antiproliferative activity; Protein tyrosine phosphatase 1B; CytocompatibilityVanadium (PubChem CID: 23990); Alginate (PubChem CID: 70678572); Sodium alginate (PubC
Keywords: پروتئین تیروزین فسفاتاز 1B; ACOX; peroxisomal acyl-coenzyme A oxidase 1; BDNF; Brain-derived neurotrophic factor; BM; bardoxolone methyl; CDDO-Im; 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; FAS; fatty acid synthase; FOXO1; Forkhead box protein O1; HF; high fat; LC; l
Keywords: پروتئین تیروزین فسفاتاز 1B; ALT; alanine transaminase; AST; aspartate transaminase; BMI; body mass index; CLD; congenital leptin deficiency; Cmax; peak serum concentration; CYP450; cytochrome P450; DXA; dual-energy X-ray absorptiometry; FGF21; fibroblast growth factor 21; FSH; folli
Keywords: پروتئین تیروزین فسفاتاز 1B; ACC; acetyl-CoA carboxylase; AgRP; agouti-related peptide; AMPK; AMP-activated protein kinase; ARC; arcuate nucleus; BAT; brown adipose tissue; CART; cocaine- and amphetamine-regulated transcript; CCK; cholecystokinin; CNS; central nervous system; FGF; fi
Keywords: پروتئین تیروزین فسفاتاز 1B; AgRP; agouti-related protein; ARC; arcuate nucleus; ASCT2; glutamine/amino acid transporter 2; B0AT1; neutral amino acid transporter 1; BBB; blood-brain barrier; CCK; cholecystokinin; CNTF; ciliary neurotrophic factor; DIO; diet-induced obesity; MCT1; m
Keywords: پروتئین تیروزین فسفاتاز 1B; BBB; blood brain barrier; ARC; arcuate nucleus of hypothalamus; NPY; neuropeptide Y; AgRP; agouti-related peptide; POMC; pro-opiomelanocortin; αMSH; α-melanocyte stimulating hormone; LepRb; leptin receptor; JAK2; janus kinase 2; STAT3; signal transducer
Keywords: پروتئین تیروزین فسفاتاز 1B; Thiazolidine-2,4-dione; Aldose reductase; Pim kinase; Protein tyrosine phosphatase 1B; Phosphoinositide 3-kinase; Mitogen activated protein kinase kinase;
Keywords: پروتئین تیروزین فسفاتاز 1B; Dual specificity phosphatases; Virtual screening methods; Phosphatases of regenerating liver; Enzyme inhibitors; Thienopyridone; 2-Cyano-2-ene-esters; DIFMUP; 6,8-difluoro-4-methylumbelliferyl phosphate; DSP; dual specificity phosphatase; MTT; 3-(4,5-dime
Keywords: پروتئین تیروزین فسفاتاز 1B; α-Amylase; Cinnamomum osmophloeum; Ferrous ion-chelating; α-Glucosidase; Protein tyrosine phosphatase 1B
Protein tyrosine phosphatase 1B inhibitory components and a new unique N-alkylamide derivative with an endoperoxide bridge from aerial parts of Indonesian Spilanthes paniculata
Keywords: پروتئین تیروزین فسفاتاز 1B; N-alkylamide; Alkamide; Spilanthes paniculata; Protein tyrosine phosphatase 1B; Inhibitor;
Synthetic and in vitro studies to indicate that the structure of the PTP1B inhibitor isolated from Acanthopanax senticosus requires reinvestigation
Keywords: پروتئین تیروزین فسفاتاز 1B; ATR; attenuated total reflectance; ESI; electrospray ionization; EtOAc; ethyl acetate; IR; infrared; PTP1B; protein tyrosine phosphatase 1B; PTP1B inhibitor; Acanthopanax senticosus; Ullmann ether synthesis; Diphenyl ether oxyneolignan;
Synthesis and biological evaluation of some N-(3-(1H-tetrazol-5-yl) phenyl)acetamide derivatives as novel non-carboxylic PTP1B inhibitors designed through bioisosteric modulation
Keywords: پروتئین تیروزین فسفاتاز 1B; Diabetes; Protein Tyrosine Phosphatase 1B; Bioisosterism; N-(3-(1H-tetrazol-5-yl)phenyl)acetamide derivatives;
Flavans and diphenylpropanes with PTP1B inhibition from Broussonetia kazinoki
Keywords: پروتئین تیروزین فسفاتاز 1B; Moraceae; Broussonetia kazinoki; Flavans; 1,3-Diphenylpropanes; Protein tyrosine phosphatase 1B;
Caged xanthones displaying protein tyrosine phosphatase 1B (PTP1B) inhibition from Cratoxylum cochinchinense
Keywords: پروتئین تیروزین فسفاتاز 1B; Cratoxylum cochinchinense; Caged xanthones; Protein tyrosine phosphatase 1B;
Possible therapeutic potential of berberine in the treatment of STZ plus HFD-induced diabetic osteoporosis
Keywords: پروتئین تیروزین فسفاتاز 1B; ROS; Reactive oxygen species; PTP1B; protein tyrosine phosphatase 1b; AMPK; adenosine monophosphate activated protein kinase; gluT1; glucose transporters; RANKL; Receptor activator of nuclear factor kappa-B ligand; NF-kB; NF-kappaB; BMSCs; bone marrow mes
Antidiabetic effects of trihydroxychalcone derivatives via activation of AMP-activated protein kinase
Keywords: پروتئین تیروزین فسفاتاز 1B; FAO; fatty acid oxidation; AMPK; AMP-activated protein kinase; AICAR; 5-aminoimidazole-4-carboxamide riboside; CPT1; carnitine palmitoyltransferase 1; ZMP; AICAR monophosphate; PTP1B; protein tyrosine phosphatase 1B; PPARγ; peroxisome proliferator-activa
Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess
Keywords: پروتئین تیروزین فسفاتاز 1B; T2D; type 2 diabetes; PTP1B; protein tyrosine phosphatase 1B; HPLC-HRMS-SPE-NMR; high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy; PNPG; p-nitrophenyl α-d-
Adiponectin inhibits hepatic stellate cell activation by targeting the PTEN/AKT pathway
Keywords: پروتئین تیروزین فسفاتاز 1B; HSCs; hepatic stellate cell; TGFβ1; Transforming growth factor β1; PTEN; Phosphatase and tensin homolog deletion 10; DNMT; DNA methyltransferase; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; CCl4; carbon tetrachloride; PTP1B; protein tyros
Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor KY-226 on experimental diabetes and obesity via enhancements in insulin and leptin signaling in mice
Keywords: پروتئین تیروزین فسفاتاز 1B; PTP1B inhibitor; Diabetes; Obesity; Allosteric inhibitor; db/db mouse; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; GLUT4; glucose transporter type 4; GPDH; glycerol-3-phosphate dehydrogenase; HbA1c; hemoglobin A1c; HFD; high-fat diet;
Inhibition of protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase by xanthones from Cratoxylum cochinchinense, and their kinetic characterization
Keywords: پروتئین تیروزین فسفاتاز 1B; Cratoxylum cochinchinense; Alkylated xanthones; Protein tyrosine phosphatase 1B; α-Glucosidase;
The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes
Keywords: پروتئین تیروزین فسفاتاز 1B; Akt2-KO; Akt2 gene deletion; CHO; Chinese hamster ovary; DM; diabetes mellitus; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ER; endoplasmic reticulum; GLUT4; glucose transporter type-4; GS; glycogen synthase; GSK-3; glycogen synt
Chalcone derivatives from the root bark of Morus alba L. act as inhibitors of PTP1B and α-glucosidase
Keywords: پروتئین تیروزین فسفاتاز 1B; Morus alba; Moraceae; Diels-Alder type adducts; Isoprenylated flavonoid; Protein tyrosine phosphatase 1B; α-Glucosidase; Molecular docking;
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes
Keywords: پروتئین تیروزین فسفاتاز 1B; T2DM; type 2 diabetes mellitus; PTP1B; protein tyrosine phosphatase 1B; BPN; 3,4-dibromo-5-(2-bromo-3, 4-dihydroxy-6-(ethoxymethyl)benzyl) benzene-1,2-diol; GLUT4; glucose transporter 4 translocation; INS; insulin; IR; insulin receptor; IRS-1; IR substrat
Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction
Keywords: پروتئین تیروزین فسفاتاز 1B; Shear stress; Nitric oxide; Protein kinase RNA-like endoplasmic reticulum kinase; Mesenteric resistance artery; Ach; Acetylcholine; ATF6; Activated Transcription Factor 6; BAX; Bcl-2-Associated X Protein; BCL2; B-Cell Lymphoma 2; CHOP; C/EBP Homologous
Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
Keywords: پروتئین تیروزین فسفاتاز 1B; 2,2â²-bipy; 2,2-bipyridine; 6-mepic; 6-methylpicolinic acid; acac; acetylacetone; Ad; adenosine; Ala; alanine; Ala-Gly; alanylglycine; Ala-His; alanylhistidine; Ala-Ser; alanylserine; Asp; aspartic acid; BEOV; bis(ethylmaltolate)oxovanadium(IV); Cys; cys
Toward the identification of a reliable 3D-QSAR model for the protein tyrosine phosphatase 1B inhibitors
Keywords: پروتئین تیروزین فسفاتاز 1B; Protein tyrosine phosphatase 1B; 3D-QSAR; CoMFA; CoMSIA; Molecular docking;
Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study
Keywords: پروتئین تیروزین فسفاتاز 1B; Diabetes mellitus; PTP1B inhibition; Flavonoids; Enzymatic inhibition type; DM; Diabetes mellitus; GLUT4; glucose transporter 4; IR; insulin receptor; IRS; insulin receptor substrates; Km; Michaelis constant; PKB; protein kinase B; pNPP; p-nitrophenyl pho
Inhibition of protein tyrosine phosphatase 1B in spinal cord dorsal horn of rats attenuated diabetic neuropathic pain
Keywords: پروتئین تیروزین فسفاتاز 1B; Protein tyrosine phosphatase 1B; Diabetic neuropathic pain; Spinal cord; Src kinase; N-methyl-D-aspartate subtype glutamate receptors;
Comprehensive review on flavonoids biological activities of Erythrina plant species
Keywords: پروتئین تیروزین فسفاتاز 1B; 5-LOX; 5-lipoxygenase; AMPK; adenosine monophosphate-activated protein kinase; Bax; Bcl-2-associated X protein; BC; lymphoma cell line; Bcl-2; B-cell CLL/lymphoma 2; Caco2; human epithelial colorectal adenocarcinoma cells; CCRF-CEM; T lymphoblastoid cell
Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics
Keywords: پروتئین تیروزین فسفاتاز 1B; SPB; structure based pharmacophore; ADMET; absorption, distribution, metabolism, excretion, and toxicity; TCPTP; T cell protein-tyrosinephosphatase; PTP1B; protein tyrosine phosphatase 1B; NS; Noonan Syndrome; JMML; juvenile myelomonocytic leukemia; AML;
ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK
Keywords: پروتئین تیروزین فسفاتاز 1B; 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; AMP-activated protein kinase; AS160; Akt Substrate of 160â¯kDa; ATF4; Activating Transcription Factor 4; AUC; area un
Alternative translation initiation of Caveolin-2 desensitizes insulin signaling through dephosphorylation of insulin receptor by PTP1B and causes insulin resistance
Keywords: پروتئین تیروزین فسفاتاز 1B; Caveolin-2; Alternative translation initiation; Insulin receptor; Protein tyrosine phosphatase 1B; Lysosomal degradation; Insulin resistance;
The chemistry and pharmacology of Ligularia przewalskii: A review
Keywords: پروتئین تیروزین فسفاتاز 1B; A375; human melanoma cells; ABTS; 2,2'-azinobis (3-ethylbenzothiazoline-6- sulfonic acid); AChE; acetylcholinesterase; AD; Alzheimer's disease; AGEs; advanced glycation endproducts; B16F10; mouse skin melanoma; BACE1; β-site amyloid precursor cleavin
Eudesmanolide sesquiterpenes and protein tyrosine phosphatase 1B inhibitory ent-kaurene diterpenes from aerial parts of Indonesian Wedelia prostata
Keywords: پروتئین تیروزین فسفاتاز 1B; Eudesmanolide sesquiterpene; ent-kaurene diterpene; Wedelia prostata; Protein tyrosine phosphatase 1B; Inhibitor;
Isoprenylated phenolic compounds with PTP1B inhibition from Morus alba
Keywords: پروتئین تیروزین فسفاتاز 1B; Morus alba; Moraceae; Isoprenylated phenolics; Albasins A-D; Protein tyrosine phosphatase 1B;