دانلود مقالات ISI درباره Protofibrils + ترجمه فارسی

بیماری آلزایمر به عنوان الیگوموپاتی

Alzheimer's disease as oligomeropathy

Keywords: Alzheimer's disease; Amyloid β-protein; Oligomers; Oligomeropathy; Aβ; amyloid β-protein; AD; Alzheimer's disease; ADDL; Aβ-derived diffusible ligands; AFM; atomic force microscopy; APP; Aβ precursor protein; APP OSK mice; APP transgenic mice express

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

ساختار الیگومرهای آمیلوئید و مکانیسم های سمیت آنها: هدف قرار دادن الیگومرهای آمیلوئید با استفاده از رویکردهای درمانی جدید

Structure of amyloid oligomers and their mechanisms of toxicities: Targeting amyloid oligomers using novel therapeutic approaches

Keywords: Protein misfolding; Amyloid oligomers; Aβ channels; Protofibrils; Fibrils; Alzheimer's disease; Prion disease; Parkinson's disease

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Aβ40 has a subtle effect on Aβ42 protofibril formation, but to a lesser degree than Aβ42 concentration, in Aβ42/Aβ40 mixtures

Keywords: Amyloid-beta protein; Aggregation; Protofibrils; Light scattering; AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; DLS; dynamic light scattering; HFIP; hexafluoroisopropanol; RH; hydrodynamic radius; Rg; root mean s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Oligomers, protofibrils and amyloid fibrils from recombinant human lysozyme (rHL): Fibrillation process and cytotoxicity evaluation for ARPE-19 cell line

Keywords: Recombinant human lysozyme; Oligomers; Protofibrils; Amyloid fibrils; ARPE-19;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

CD47 does not mediate amyloid-β(1-42) protofibril-stimulated microglial cytokine release

Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; IL-1β; interleukin-1β; SEC; size exclusion chromatography; ThT; thioflavin T; TNFα; tumor necrosis factor α; Amyloid-beta protein; A

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Detection and analysis of protofibrils and fibrils of hemoglobin: Implications for the pathogenesis and cure of heme loss related maladies

Keywords: Cytotoxic; Fibrils; Heme loss; Protofibrils

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice

Keywords: Aβ; Oligomers; Protofibrils; Senile plaques; Dendrites; Synapses; Toxicity;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

PrP N-terminal domain triggers PrPSc-like aggregation of Dpl

Keywords: Prion protein; PrP N-terminal domain; Doppel; Aggregation; Limited proteolysis; Protofibrils

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Dissecting the 3-D structure of vimentin intermediate filaments by cryo-electron tomography

Keywords: Vimentin; Intermediate filament; Protofibrils; Cryo-electron tomography

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins

Keywords: Amyloid; Fibrils; Fluorescence probes; Oligomers; Protofibrils; Membrane permeability; Aggregation; Toxicity; Fluorescence resonance energy transfer; Fluorescence correlation spectroscopy; Fluorescence anisotropy

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2007 سفارش ترجمه

Apomyoglobin reveals a random-nucleation mechanism in amyloid protofibril formation

Keywords: Amyloid; Aggregation; Apomyoglobin; Protein folding; Protofibrils

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Structural Differences in Aβ Amyloid Protofibrils and Fibrils Mapped by Hydrogen Exchange – Mass Spectrometry with On-line Proteolytic Fragmentation

Keywords: AD, Alzheimer's disease; APP, amyloid precursor protein; HX-MS, hydrogen-deuterium exchange-mass spectrometry; D, deuterium; CLC, calmidazolium chloride; ESI, electrospray ionization; LCamyloid fibrils; protofibrils; hydrogen-deuterium exchange; mass spec

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

High-resolution Atomic Force Microscopy of Soluble Aβ42 Oligomers

Keywords: Alzheimer's disease; amyloid beta; soluble oligomer; protofibrils; atomic force microscopyAFM, atomic force microscopy; APP, amyloid precursor protein; EM, electron microscopy; FTIR, Fourier transform infrared; MW, molecular weight; MPL, mass-per-length;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Probing the Mechanism of Amyloidogenesis through a Tandem Repeat of the PI3-SH3 Domain Suggests a Generic Model for Protein Aggregation and Fibril Formation

Keywords: amyloid fibrils; assembly mechanism; nucleation; protofibrils; PI3-SH3 domainPI3-SH3, SH3 domain of the α-subunit of bovine phosphatidyl-3′-kinase; SH3SD, PI3-SH3 single domain; SH3TR, PI3-SH3 tandem repeat; FTIR, Fourier transform infrared spectroscopy;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2006 سفارش ترجمه