
Keywords: PRRs، گیرندههای شناسایی الگو; TLRs, Toll-like receptors; RA, Rheumatoid arthritis; PRRs, Pattern Recognition Receptors; ED, Ectodomain; NFκB, nuclear factor kappa-light-chain-enhancer of activated B cells; PAMPs, Pathogen Associated Molecular Patterns; HMGB-1, high mobility group box-