Keywords: PtdIns (3،4،5) P3; Parkinson's disease; Striatum; Rotenone; Phospholipids; Dye-lipid complex; PD; Parkinson's disease; AD; Alzheimer's disease; DA; Dopaminergic neuron; SNpc; Substantia nigra pars compacta; ROT; Rotenone; DMSO; Dimethyl sulfoxide; PLs; Phospholipids; PC; Ph
مقالات ISI PtdIns (3،4،5) P3 (ترجمه نشده)
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Keywords: PtdIns (3،4،5) P3; Phosphatidylinositol; PtdIns(3,4,5)P3; Akt; mTORC1; Phosphorylated phosphatidylinositides; GLUT4;
Keywords: PtdIns (3،4،5) P3; AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch
Kindlins: Roles in development and cancer progression
Keywords: PtdIns (3،4،5) P3; AML; acute myeloid leukemia; AR; androgen receptor; CRC; colorectal cancer; DC; dendritic cells; EC; esophageal cancer; ECM; extracellular matrix; EMT; endothelial/mesenchymal transition; ESCC; esophageal squamous cell cancer; FERM; 4.1-ezrin-ridixin-moes
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain
Keywords: PtdIns (3،4،5) P3; PtdIns(3,4,5)P3; Pleckstrin homology (PH) domain; PDK1; Flavonoid; QSAR;
BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation
Keywords: PtdIns (3،4،5) P3; DAG; diacylglycerol; PPIns; phosphoinositides; RTK; receptor tyrosine kinase; GPCR; G-protein coupled receptor; Ins(1,4,5)P3; inositol 1,4,5-trisphosphate; PM; plasma membrane; BRET; bioluminescence resonance energy transfer; PLC; phospholipase C; PtdIns(
Small chemicals with inhibitory effects on PtdIns(3,4,5)P3 binding of Btk PH domain
Keywords: PtdIns (3،4،5) P3; Btk PH domain; PtdIns(3,4,5)P3; In silico docking; Small chemicals
BMX Acts Downstream of PI3K to Promote Colorectal Cancer Cell Survival and Pathway Inhibition Sensitizes to the BH3 Mimetic ABT-737
Keywords: PtdIns (3،4،5) P3; CRC; colorectal cancer; PI3K; phosphoinositide 3-kinase; PtdIns(3,4,5)P3; phosphatidylinositol-3,4,5-triphosphate; PH; pleckstrin homology; siRNA; small interfering RNA; SRB; sulforhodamine B;
Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis
Keywords: PtdIns (3،4،5) P3; ALD; alcoholic liver disease; ALT; alanine aminotransferase; ChREBP; carbohydrate response element-binding protein; 4-HNE; 4-hydroxy-2-nonenal; NASH; nonalcoholic steatohepatitis; PI3K; phosphatidylinositol 3-kinase; PtdIns(3,4,5)P3; phosphatidylinositol
ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences
Keywords: PtdIns (3،4،5) P3; PH; Pleckstrin Homology; PI3K; Phosphatidyl 3OH Kinase; PtdIns(3,4,5)P3; Phosphatidylinositol-(3,4,5)-trisphosphate; PtdIns(3,4)P2; Phosphatidylinositol-(3,4)-bisphosphate; GAP; GTPase Activating Protein; SAM; Sterile Alpha Motif; SHIP2; SH2-containing in
Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate
Keywords: PtdIns (3،4،5) P3; Metabolically-stabilized; PtdIns(3,4,5)P3; Asymmetric synthesis; Activating sodium transport;
aPKC restricts the basolateral determinant PtdIns(3,4,5)P3 to the basal region
Keywords: PtdIns (3،4،5) P3; aPKC; PtdIns(3,4,5)P3; PIP3; PtdIns(4,5)P2; PIP2; AktPH; PTEN; Membrane domain; Epithelial cell polarity; MDCK cells
The docking properties of SHIP2 influence both JIP1 tyrosine phosphorylation and JNK activity
Keywords: PtdIns (3،4،5) P3; SHIP2; SH2-domain containing inositol polyphosphate 5-phosphatase 2; JNK; c-Jun N-terminal kinase; JIP1; JNK-interacting protein 1; MLK3; mixed-lineage kinase3; MAPK; mitogen-activated protein kinase; MKK7; MAPK kinase 7; DLK; dual leucine zipper-bearing
Intranuclear 3′-phosphoinositide metabolism and Akt signaling: New mechanisms for tumorigenesis and protection against apoptosis?
Keywords: PtdIns (3،4،5) P3; PtdIns(3,4,5)P3; PI3K; Akt; Nucleus; Apoptosis; Cancer; Cardiovascular disorders
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
Keywords: PtdIns (3،4،5) P3; cisplatin; cisdiamminedichloroplatinum; PI3K; phosphatidylinositol 3-kinase; PtdIns(3,4)P2; phosphatidylinositol-3,4-biphosphate; PtdIns(3,4,5)P3; phosphatidylinositol-3,4,5-triphosphate, siRNA, small interfering RNA; RT; reverse transcription; OVCAR-3 ce