Keywords: پری گلوتامات; (AR); apelin receptor/APJ/APLNR; (BSA); bovine serum albumin; (CD); circular dichroism; (CSD); chemical shift displacement; (CSI); chemical shift index; (DANGLE); dihedral angles from global likelihood estimates; (ERK); extracellular signal-regulated kina
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Keywords: پری گلوتامات; AD; atopic dermatitis; α2HS-GP; alpha-2-HS-glycoprotein; CCL20; C-C motif ligand 20; CCR2; C-C chemokine receptor type 2; CRP; C-reactive protein; CYA; ciclosporin; DC; dendritic cells; Dkk-1; dickkopf-related protein 1; dMVECs; dermal microvascular
Keywords: پری گلوتامات; Aging; Oxidative stress; Lipid peroxidation; Neuronal excitability; Electrophysiology; Glutathione imaging; Lymnaea stagnalis; Redox balance; Identified neuron; γ-Glutamylcysteine synthetase inhibition; Mollusk; Pyroglutamate;
Oxopiperazine capping: Formation of oxopiperazine-containing peptoids via C-terminal cyclization
Keywords: پری گلوتامات; Peptoid; Cyclization; Side reaction; Oxopiperazine; Aspartimide; Pyroglutamate;
Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients
Keywords: پری گلوتامات; PGA; pyroglutamic acid; HILIC; hydrophilic interaction liquid chromatography; ICU; intensive care unit; Pyroglutamate; Oxoproline; Metabolic acidosis; Anion gap; Hydrophilic interaction chromatography; Mass spectrometry;
Metabonomics screening of serum identifies pyroglutamate as a diagnostic biomarker for nonalcoholic steatohepatitis
Keywords: پری گلوتامات; Non-alcoholic fatty liver disease; Nonalcoholic steatohepatitis; Simple steatosis; Metabolic profiling; Pyroglutamate;
Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid
Keywords: پری گلوتامات; Aβ; amyloid-β; AD; Alzheimer's disease; ANS; 8-anilinonapthalene-1-sulfonic acid; CAA; cerebral amyloid angiopathy; CAPS; 3-cyclohexamino-1-propanesulfonic acid; CD; circular dichroism; CNS; central nervous system; cyt c; cytochrome c; DCFDA; 2â²,7â²-
A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects
Keywords: پری گلوتامات; Alzheimer's disease; Glutaminyl cyclase; QC inhibitor; Amyloid-beta; Pyroglutamate; pE-Aβ; Cerebrospinal fluid
Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase
Keywords: پری گلوتامات; 4-Oxalocrotonate tautomerase; Methionine aminopeptidase; 5-Oxoproline; Pyroglutamate; Demethionylation
Comparative properties of Aβ1-42, Aβ11-42, and [Pyr11]Aβ11-42 generated from O-acyl isopeptides
Keywords: پری گلوتامات; Aβ; Click peptide; Isopeptide; Pyroglutamate;
Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template
Keywords: پری گلوتامات; Glutaminyl cyclase; QC; Alzheimer's disease; Beta amyloid; Pyroglutamate; Enzyme inhibitor;
Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias
Keywords: پری گلوتامات; Familial British dementia; Familial Danish dementia; Amyloid; Pyroglutamate; Transgenic mice; Aggregation; Toxicity; ABri; ADan;
HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium
Keywords: پری گلوتامات; 5-Oxoproline; Pyroglutamate; Glutathione; Oxidative stress; Hepatotoxicity;
Reduced levels of IgM autoantibodies against N-truncated pyroglutamate Aβ in plasma of patients with Alzheimer's disease
Keywords: پری گلوتامات; Alzheimer's disease; Autoantibody; Aβ; Biomarker; Plasma; Pyroglutamate
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter
Keywords: پری گلوتامات; Pyroglutamate; Renal reabsorption; SLC5A8; Monocarboxylate transporter
Amyloid-beta peptide Aβp3-42 affects early aggregation of full-length Aβ1-42
Keywords: پری گلوتامات; Alzheimer's disease; Amyloid-beta peptides; Aggregation; Pyroglutamate;
Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group
Keywords: پری گلوتامات; Anti-HIV peptide; Fusion inhibitor; HIV; Pyroglutamate
Analysis of glutamine, glutamate, pyroglutamate, and GABA in cerebrospinal fluid using ion pairing HPLC with positive electrospray LC/MS/MS
Keywords: پری گلوتامات; Glutamate; Glutamine; Pyroglutamate; GABA; LC/MS/MS; HFBA; Ion pairing; CSF
Stereoselective formal synthesis of the potent proteasome inhibitor: salinosporamide A
Keywords: پری گلوتامات; Proteasome inhibitor; Salinosporamide A; Pyroglutamate; 1,3-Dipolar cycloadditions; N-Methylnitrone; Selective O-benzylation;
Synthetic approaches to peptides containing the l-Gln-l-Val-D(S)-Dmt motif
Keywords: پری گلوتامات; Dimethylthiaproline; Pseudoproline; Prostate-specific antigen; Peptide synthesis; Pyroglutamate
Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature
Keywords: پری گلوتامات; Recombinant monoclonal antibody; Peptide mapping; Deamidation; Pyroglutamate
Roles of N-terminal Pyroglutamate in Maintaining Structural Integrity and pKa Values of Catalytic Histidine Residues in Bullfrog Ribonuclease 3
Keywords: پری گلوتامات; pyroglutamate; ribonuclease; NMR; pKa; dynamicsPyr1, N-terminal pyroglutamate residue; pRNase 3, recombinant RC-RNase 3 with Pyr1; mqRNase 3, recombinant RC-RNase 3 with an additional Met-1 residue and Gln1 instead of Pyr1 at the N terminus; RNase 3, nati
High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain
Keywords: پری گلوتامات; mass spectrometry; pathological aging; pyroglutamate; ultrastructure; laser dissection microscopy; Alzheimer’s diseaseAD, Alzheimer’s disease; Aβ, amyloid beta peptide; APP, amyloid precursor protein; BSA, bovine serum albumin; CAA, cerebral amyloid angio
[1,2] Boc migration during pyroglutamate alkylations
Keywords: پری گلوتامات; Boc migration; Pyroglutamate; Alkylation; Carbamates;
Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: A single zinc metalloenzyme
Keywords: پری گلوتامات; Human glutaminyl cyclase; Pyroglutamate; Posttranslational modification; X-ray crystallography; Bone marrow; Escherichia coli; Atomic absorption; Zinc ion;