Keywords: پیرولوبenzodiazepine; Hypoxia; Prodrug; Pyrrolobenzodiazepine; P450-reductase;
مقالات ISI پیرولوبenzodiazepine (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Immunotherapy for acute myeloid leukemia (AML): a potent alternative therapy
Keywords: پیرولوبenzodiazepine; AML; acute myeloid leukemia; GO; gemtuzumab ozogamacin; PBD; pyrrolobenzodiazepine; HuM196; humanized murine 196; CARs; chimeric antigen receptors; LAA; leukemia associated antigens; TCRT; cell receptor; NKG2D; natural killer group 2 D; MHC; major histoco
Topical delivery of anthramycin II. Influence of binary and ternary solvent systems
Keywords: پیرولوبenzodiazepine; Anthramycin; Pyrrolobenzodiazepine; Solvents; Skin; Permeation; Mass balance;
An optimised synthesis of SG3376, a non-cleavable antibody-drug conjugate pyrrolobenzodiazepine drug-linker
Keywords: پیرولوبenzodiazepine; Antibody-drug conjugates; Pyrrolobenzodiazepine; BOC deprotection; Talirine; Tesirine;
The use of molecular dynamics simulations to evaluate the DNA sequence-selectivity of G-A cross-linking PBD-duocarmycin dimers
Keywords: پیرولوبenzodiazepine; DNA cross-linking; Pyrrolobenzodiazepine; Duocarmycin; PBD-CPI dimer; Molecular dynamics; PBD; CPI; CBI; Seco-amino CI;
Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates
Keywords: پیرولوبenzodiazepine; ADC; antibody-drug conjugate; BINAP; 2,2â²-bis(diphenylphosphino)-1,1â²-binaphthalene; CBI; 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; EDCI; N-ethyl-Nâ²-(3-dimethylaminopropyl)carbodiimide hydrochloride; MMAE; monomethyl auristatin E; PBD; p
Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as p53-dependent and -independent apoptogenic signaling in melanoma cells
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Mitochondria; Gallic acid; Antitumor; Free radical; MelanomaPBD-GA, pyrrolo[2,1-c] [1,4]benzodiazepine-Gallic; QSAR, quantitative structural activity relationship; ROS, reactive oxygen species; DNA, deoxyribonucleic acid; ATR, ataxi
Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: Synthesis, DNA-binding affinity and cytotoxic activity
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Piperazine; Dithiocarbamates; DNA-binding affinity; Cytotoxicity
Azide based routes to tetrazolo and oxadiazolo derivatives of pyrrolobenzodiazepines and pyrrolobenzothiadiazepines
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Pyrrolobenzothiadiazepine; Tetrazole; 1,2,4-Oxadiazole; Glut-1 inhibitor; Pyrrole synthesis;
Synthesis and biological evaluation of estradiol linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates as potential anticancer agents
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Estradiol; Anticancer agents; Tubulin polymerisation; Apoptosis; Tunel assay; p53; p21; HDACs
Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Anthranilamide; Anticancer activity; Apoptosis; p53; Active caspase-3;
Synthesis and biological evaluation of anilino substituted pyrimidine linked pyrrolobenzodiazepines as potential anticancer agents
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; DNA-binding affinity; Cytotoxicity; Cytochrome c; p53; Poly ADP ribose polymerase (PARP); Apoptosis;
Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; 2,5-Diaryloxadiazoles; Anticancer activity; Apoptosis; p53; Caspases; Cyclin dependent kinase-2 (CDK-2);
Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; 3,5-Diaryl-isoxazoline/isoxazole; p53; Cytochrome c; Procaspase-3
Synthesis and biological evaluation of cinnamido linked pyrrolo[2,1-c][1,4]benzodiazepines as antimitotic agents
Keywords: پیرولوبenzodiazepine; Invitro cytotoxicity; Inhibition of tubulin polymerization; Cell cycle arrest; Pyrrolobenzodiazepine; Cinnamido component
Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Benzothiazole; Benzoxazole, DNA-binding affinity; Anticancer activity; Molecular modelling; In vivo efficacy
Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Quinazolinone; DNA binding affinity; Anticancer activity; Molecular modeling; Molecular dynamics; Apoptosis; p53; p21; p27; NF-κB; Cytochrome-c; B-cell lymphoma 2 (Bcl-2); Cyclin dependent kinase-2 (CDK-2); Active caspase-3; Poly (A
Spectroscopic and calorimetric studies on the DNA recognition of pyrrolo[2,1-c][1,4]benzodiazepine hybrids
Keywords: پیرولوبenzodiazepine; Calorimetry; DNA recognition; Pyrrolobenzodiazepine; Spectroscopy
Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Fluoro; Piperazine; DNA-binding affinity; Anticancer activity
Enantiospecific synthesis of 5-phenylpyrrolo[2,1-c][1,4]benzodiazepines
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Xanthene; Proline; Benzodiazepinone; Cyclodehydration;
Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Benzimidazoles; In vitro cytotoxicity; DNA-binding affinity
An asymmetric C8/C8′-tripyrrole-linked sequence-selective pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer DNA interstrand cross-linking agent spanning 11 DNA base pairs
Keywords: پیرولوبenzodiazepine; DNA-binding; Sequence-selective; Interstrand; Cross-linking; Anticancer agent; Pyrrolobenzodiazepine; PBD; PBD dimer
Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates
Keywords: پیرولوبenzodiazepine; Triazolobenzothiadiazines; Pyrrolobenzodiazepine; Antitumour activity; DNA-binding ability
Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Diethylphosphonate; DNA-binding affinity; Cytotoxicity
Synthesis and DNA-binding ability of C2R-fluoro substituted DC-81 and its dimers
Keywords: پیرولوبenzodiazepine; DNA-binding ability; Pyrrolobenzodiazepine; DC-81
Identification of the benzodiazepines as a new class of antileishmanial agent
Keywords: پیرولوبenzodiazepine; Antileishmanial agents; Amastigote; Benzodiazepine; Pyrrolobenzodiazepine; Paullone
Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugates
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Hydroxyazepane; DNA-binding ability
DNA binding potential and cytotoxicity of newly designed pyrrolobenzodiazepine dimers linked through a piperazine side-armed-alkane spacer
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; DNA-binding ability; Cytotoxicity; Piperazine
Action of a novel pyrrolo[1,2-c][1.3]benzodiazepine on the viability of Jurkat and neuronal/glial cells
Keywords: پیرولوبenzodiazepine; Pyrrolobenzodiazepine; Neuronal/glial cells; Transformed Jurkat cells; DNA cleavage
Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136
Keywords: پیرولوبenzodiazepine; SJG-136; Pyrrolobenzodiazepine; Interstrand cross-linking agent; DNA-binding; Minor-groove; ABCB1; mdr-1; Drug resistance; Colon cancer; Ovarian cancer;