دانلود مقالات ISI درباره QC، کنترل کیفیت + ترجمه فارسی

Liquid chromatography–tandem mass spectrometric assay for the VEGFR inhibitor cediranib and its primary human metabolite cediranib-N+-glucuronide in plasma

Keywords: QC، کنترل کیفیت; HESI, heated electrospray ionization; LLOQ, lower limit of quantification; SRM, selected reaction monitoring; QC, quality control; VEGFR, vascular endothelial growth factor receptorCediranib; Cediranib-N+-glucuronide; VEGF inhibitor; LC–MS/MS; Human plasm

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS

Keywords: QC، کنترل کیفیت; ACN, acetonitrile; ANOVA, analysis of variance; AUC, area under curve; CL, clearance; HPLC, high performance liquid chromatography; IS, internal standard; MRT, mean residence time; MRM, multiple reaction monitoring; QC, quality control; SE, standard error

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetics of protocatechuic acid in mouse and its quantification in human plasma using LC–tandem mass spectrometry

Keywords: QC، کنترل کیفیت; PCA, protocatechuic acid; NHBC, 3-nitro-4-hydroxybenzoic acid; BRB, black raspberry; ACN, acetonitrile; FA, Formic acid; QC, quality control; LLOQ, lower limit of quantification; HPLC, high performance liquid chromatography; LC–MS, liquid chromatography–m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A validated bioanalytical method in mouse, rat, rabbit and human plasma for the quantification of one of the steroid glycosides found in Hoodia gordonii extract

Keywords: QC، کنترل کیفیت; HPLC, high performance liquid chromatography; FDA, Food and Drug Administration; LLE, liquid–liquid extraction; LC–MS/MS, liquid chromatography tandem mass spectrometry; MRM, multiple reaction monitoring; MTBE, methyl-tert-butyl ether; QC, quality control

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches

Keywords: QC، کنترل کیفیت; BC, buffy coat; CBS, Canadian Blood Services; Hct, hematocrit; HiCN, cyanmethemoglobin; ICSH, International Committee on Standardization in Hematology; MCV, mean cell volume; metHB, methemoglobin; QC, quality control; RBC, red blood cell; RCC, red cell co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Fetal bisphenol A exposure: Concentration of conjugated and unconjugated bisphenol A in amniotic fluid in the second and third trimesters

Keywords: QC، کنترل کیفیت; BPA, bisphenol A; CV, coefficient of variation; HPLC, high-performance liquid chromatography; IS, internal standard; LOD, limit of detection; LOQ, limit of quantitation; LC–MS, liquid chromatography–mass spectrometry; QC, quality control; SPE, solid phase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Development and application of high-performance liquid chromatography for the study of two new oxyprenylated anthraquinones produced by Rhamnus species

Keywords: QC، کنترل کیفیت; CV, coefficient of variation; LOD, limit of detection; LOQ, limit of quantification; ODS, octadecylsilane; QC, quality control; TFA, trifluoroacetic acid; ULOQ, upper limit of quantificationExtraction procedure; HPLC–UV/vis; Method development; Oxyprenyla

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Validation of a gyrolab™ assay for quantification of rituximab in human serum

Keywords: QC، کنترل کیفیت; PK, pharmacokinetics; ELISA, enzyme-linked immunosorbent assay; CD, compact disk; PBS, phosphate buffered saline; HABA, 4′-hydroxyazobenzene-2-carboxylic acid; QC, quality control; LLOQ, lower limit of quantification; ULOQ, upper limit of quantification;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Determination of phenylbutyric acid and its metabolite phenylacetic acid in different tissues of mouse by liquid chromatography with tandem mass spectrometry and its application in drug tissue distribution

Keywords: QC، کنترل کیفیت; AUC, area under curve; d11-PBA, d11-phenylbutyric acid; d7-PAA, d7-phenylacetic acid; PAA, phenylacetic acid; PBA, phenylbutyric acid; RSD, relative standard deviation; PAGN, phenylacetylglutamine; PBGN, phenybutyrylglutamine; QC, quality control; i.p., i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Production of uniformly sized serum albumin and dextrose microbubbles

Keywords: QC، کنترل کیفیت; BSA, bovine serum albumin; CW, continuous wave; HSA, human serum albumin; MBs, microbubbles; PBS, phosphate buffered saline; QC, quality control; SA, serum albumin; STT, size transition time pointMicrobubble; Ultrasound; Contrast agent; Production; Sonica

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Quantification of lactose content in human and cow's milk using UPLC–tandem mass spectrometry

Keywords: QC، کنترل کیفیت; AOAC, Association of Official Analytical Chemists; CAD, corona charged aerosol detector; CMTL, Central Milk Testing Laboratory; CV, coefficient of variation; HPLC, high pressure liquid chromatography; QC, quality control; UPLC–MS/MS, ultra performance liq

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Simultaneous determination of the flavonoids robinin and kaempferol in human breast cancer cells by liquid chromatography-tandem mass spectrometry

Keywords: QC، کنترل کیفیت; LC–MS/MS, liquid chromatography–tandem mass spectrometric; QC, quality control; I.S., internal standardLC/MS/MS; Robinin; Kaempferol; Analysis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Bioanalysis in clinical development of tasquinimod using liquid chromatography/tandem mass spectrometry

Keywords: QC، کنترل کیفیت; CRPC, castrate resistant prostate cancer; LC–MS/MS, liquid chromatography coupled to tandem mass spectrometry; IS, internal standard; SRM, selected reaction mode; ESI, electrospray ionization; TFA, trifluoroacetic acid; QC, quality control; LLOQ, lower li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Application of the β-expectation tolerance interval to method validation of the M30 and M65 ELISA cell death biomarker assays

Keywords: QC، کنترل کیفیت; QC, quality control; CK18, cytokeratin 18; 4-PL, 4-paramter logistic functionM30 ELISA; M65 ELISA; Method validation; β-expectation tolerance interval

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Patient-specific measures of a biomarker for the generation of individual reference intervals: hemoglobin as example

Keywords: QC، کنترل کیفیت; ANOVA, analysis of variance; BN, Bayesian network; CHN, China; CI, confidence interval; CV, coefficient of variation; EEU, Eastern Europe; FDA, Food and Drug Administration; Hb, hemoglobin concentration; QC, quality control; TA, therapeutic area; WEU, Wes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Validation of immunoassay for protein biomarkers: Bioanalytical study plan implementation to support pre-clinical and clinical studies

Keywords: QC، کنترل کیفیت; AAPS, American association of pharmaceutical scientists; ACC, accuracy; STD, calibration standard; LLOQ, lower limit of quantification; MRD, minimum required dilution; CV, precision; QC, quality control; ULOQ, upper limit of quantificationImmunoassay; End

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

HPLC analysis of mitoxantrone in mouse plasma and tissues: Application in a pharmacokinetic study

Keywords: QC، کنترل کیفیت; I.S., internal standard; QC, quality control; TEA, triethylamine; LLOQ, lower limit of quantificationMitoxantrone; Assay; Pharmacokinetic; Plasma and tissue concentrations

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate

Keywords: QC، کنترل کیفیت; ESI, electrospray ionization; IS, internal standard; LC/MS, liquid chromatography/mass spectrometry; LLOQ, lowest limit of quantification; OZ, ozonide; PK, pharmacokinetic; QC, quality control; RSD, relative standard deviation; USFDA, US Food and Drug Adm

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

An efficient HPLC method for the quantitative determination of atazanavir in human plasma suitable for bioequivalence and pharmacokinetic studies in healthy human subjects

Keywords: QC، کنترل کیفیت; ATV, atazanavir; PI, protease inhibitor; ARVs, antiretrovirals; DIAZ, diazepam; IS, internal standard; QC, quality control; LLOQ, lower limit of quantification; % RSD, percentage relative standard deviation; % RE, percentage relative errorHPLC-UV; Atazana

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Physiology and pathology of proteostasis in the early secretory compartment

Keywords: QC، کنترل کیفیت; BCR, B cell receptor; ER, endoplasmic reticulum; ERAD, ER associated degradation; ERGIC, ER-Golgi intermediate compartment; ESC, early secretory compartment; QC, quality control; RB, Russell bodies; UPR, unfolded protein responseB cell differentiation; ER

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxycortisol with ultra high performance liquid chromatography–tandem mass spectrometry: Application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory

Keywords: QC، کنترل کیفیت; UHPLC MS/MS, ultra high performance liquid chromatography–tandem mass spectrometry; HPLC, high performance liquid chromatography; 11βHSD, 11β-hydroxysteroid dehydrogenase; QC, quality control; IA, immuno-assay; CBG, corticosteroid-binding globulin; ACTH,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography–electrospray tandem mass spectrometry

Keywords: QC، کنترل کیفیت; BSA, bovine serum albumin; FWHM, full-width at half-maximum; IS, internal standard; LLOQ, lower limit of quantification; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; QC, quality control; TEA, triethylamineLysophosphatidic acid (LPA); Lysophos

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Validation of cell density and viability assays using Cedex automated cell counter

Keywords: QC، کنترل کیفیت; GVAX immunotherapy; Cedex automatic cell counter; Analytical method validationGM-CSF, granulocyte-macrophage colony-stimulating factor; QC, quality Control; RSD, relative standard deviation/coefficient of variance; R2, coefficient of determination; DOE, d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Comparison of potency assays using different read-out systems and their suitability for quality control

Keywords: QC، کنترل کیفیت; MTS/PMS, (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl-2-(4-sulfophenyl)-2H-tetrazolium)/ phenazine methosulfate); ATP, adenosine triphosphate; QC, quality control; EGFr, Epidermal Growth Factor receptor; IL, interleukin; API, active pharmaceuti

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Real-time evaluation of experimental variation in large-scale LC–MS/MS-based quantitative proteomics of complex samples

Keywords: QC، کنترل کیفیت; LC, liquid chromatography; MS, mass spectrometry; MSE, type of MS acquisition mode (expression mode); kDa, kilo Dalton; SD, standard deviation; RSD, relative standard deviation; QC, quality control; PLGS, Proteinlynx Global Server; FCS, fetal calf serum;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

In vivo pharmacokinetics comparisons of icariin, emodin and psoralen from Gan-kang granules and extracts of Herba Epimedii, Nepal dock root, Ficus hirta yahl

Keywords: QC، کنترل کیفیت; GKG, Gan-kang granules; ICH, International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use; IS, internal standard; LLOQ, lower limit of quantification; QC, quality control; RE, relative deviation; RS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Determination of d-limonene in adipose tissue by gas chromatography–mass spectrometry

Keywords: QC، کنترل کیفیت; GC–MS, gas chromatography/mass spectrometry; QC, quality control; HPLC, high performance liquid chromatography; KOH, potassium hydroxided-Limonene; GC–MS; Adipose

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Development and evaluation of real-time loop-mediated isothermal amplification for hepatitis B virus DNA quantification: A new tool for HBV management

Keywords: QC، کنترل کیفیت; HBV, hepatitis B virus; LAMP, loop-mediated isothermal amplification; QC, quality control; real-time PCR, real-time polymerase chain reaction; LDL, low detection limit; TTP, time-to-positiveHBV; LAMP; Real-time PCR; Serum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A rugged and transferable method for determining blood cadmium, mercury, and lead with inductively coupled plasma-mass spectrometry

Keywords: QC، کنترل کیفیت; APDC, ammonium pyrolidinedithiocarbamate; cps, counts per second; EDTA, ethylenediaminetetraacetic acid and/or its salts; ICP-MS, inductively coupled plasma-mass spectrometry; QC, quality control; SRM, standard reference material; TMAH, tetramethylammoniu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Environmental lead exposure, maternal thyroid function, and childhood growth

Keywords: QC، کنترل کیفیت; BMI, body-mass index; BPb, blood lead; CI, confidence interval; FT4, free thyroxine; T4, thyroxine; T3, triiodothyronine; TSH, thyroid stimulating hormone; RIA, radioimmunoassay procedure; QC, quality control; ng/dL, nanograms/deciliter; μIU/mL, micro-int

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

An automated, highly sensitive LC-MS/MS assay for the quantification of the opiate antagonist naltrexone and its major metabolite 6β-naltrexol in dog and human plasma

Keywords: QC، کنترل کیفیت; APCI, atmospheric pressure chemical ionization; EDTA, ethylene diamino tetra acetylic acid; LLOQ, lower limit of quantitation; MRM, multiple reaction monitoring; m/z, mass/charge; QC, quality control; R.S.D.%, residual standard deviation in %Naltrexone; 6

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Simultaneous determination of multiple angiotensin type 1 receptor antagonists and its application to high-throughput pharmacokinetic study: Cassette dosing versus cassette analysis

Keywords: QC، کنترل کیفیت; AT1RAs, angiotensin type 1 receptor antagonists; LC–MS/MS, high performance liquid chromatography-electrospray tandem mass spectrometry; QC, quality control; LLOQ, lower limit of quantification; SRM; selective reaction monitoring; LLE, liquid–liquid extra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

A sensitive assay for simultaneous determination of plasma concentrations of valganciclovir and its active metabolite ganciclovir by LC/MS/MS

Keywords: QC، کنترل کیفیت; DI, deionized; QC, quality control; LLOQ, lowest level of quantitationValganciclovir; Ganciclovir; Aciclovir; LC/MS/MS; Protein precipitation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Quantitative determination of trans-polydatin, a natural strong anti-oxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies

Keywords: QC، کنترل کیفیت; HPLC, high performance liquid chromatography; IS, internal standard; QC, quality control; LLOQ, lower limit of quantification; RE, relative error; RSD, relative standard deviation; CV, coefficient of variation; AE, absolute recovery; Caco-2, human colon a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Determination of eprosartan in human plasma and urine by LC/MS/MS

Keywords: QC، کنترل کیفیت; DI, deionized; QC, quality control; LLOQ, lowest level of quantitationEprosartan; LC/MS/MS; Protein precipitation; Plasma; Urine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent

Keywords: QC، کنترل کیفیت; MSC, methylselenocysteine; Se, selenium; MTD, maximum tolerated dose; CR, cure rates; i.v., intravenously; s.c., subcutaneously; QC, quality control; AUC, area under the concentration time curveMethylselenocysteine; Selenium; FaDu; A253; Irinotecan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

New validated method for piracetam HPLC determination in human plasma

Keywords: QC، کنترل کیفیت; SC, Stock Solution; WC, Working Solution; STD, Standard Plasma Solutions; QC, Quality Control; LLQ, Lower Limit of Quantification; PPS, Post-Preparative Stability; FTS, Freeze-Thaw Stability; LTS, Long-Term Stability; SD, Standard Deviation; CV%, Coeffici

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Oxidative stress in children receiving valproic acid

Keywords: QC، کنترل کیفیت; VPA, Valproic acid; 15-F2t-IsoP, 15-F2t-Isoprostane; CBZ, Carbamazepine; CLB, Clobazam; ROS, Reactive oxygen species; QC, Quality control

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Sensitive assay for determining plasma tenofovir concentrations by LC/MS/MS

Keywords: QC، کنترل کیفیت; DI, deionized; QC, quality control; IDV, indinavir; DLV, delavirdine; APV, amprenavir; NFV, nevirapine; M8, nelfinavir metabolite; SQV, saquinavir; EFV, efavirenz; RTV, ritonavir; LPV, lopinavir; ATV, atazanavir; 3TC, lamivudine; d4T, stavudine; AZT, zido

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Development of a sensitive LC-ESI-MS assay for 20(R)-ginsenoside Rh2 and its pharmacokinetic application in dogs: A case for the influence of micronization on traditional Chinese medicine

Keywords: QC، کنترل کیفیت; LC-ESI-MS, liquid chromatography-electrospray ionization-mass spectrometry; SIM, selective ion monitoring; LOD, limit of detection; LLOQ, lower limit of quantitation; TCM, traditional Chinese medicine; IS, internal standard; QC, quality control; CDL, curv

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه