Keywords: T1DM; Type 1 diabetes mellitus; EDS; Search E-Resources; IGF1; insulin-like growth factor 1; NOD; non-obese diabetic; G6Pase; glucose-6-phosphatase; HGF; hepatocyte growth factor; SCID; severe combined immunodeficiency; BTC; betacellulin; Ngn3; Neurogenin
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Narcolepsy; Cataplexy; Orexin; Hypocretin; Neurodegeneration; Animal models; 5-HT; 5-hydroxytrytamine (serotonin); α1; noradrenergic alpha 1 receptor; α2; noradrenergic alpha 2 receptor; ACh; acetylcholine; Atax; orexin/ataxin-3 transgenic; BAC; bacteri
Keywords: ACI; Autologous chondrocyte implantation; ACPCs; Articular cartilage progenitor cells; ASCs; Adipose stem cells; BMP; Bone morphogenetic protein; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large; BCA-1; B cell-attracting chemokine 1; CCR6;
Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; rAAV; recombinant adeno-associated virus; NBD; nucleotide binding domain; MSD; membrane spanning domain; iPSC; induced pluripotent stem cells; CRC; conditionally reprogrammed cells; ROCK; Rho-kina
Use of modified U1 small nuclear RNA for rescue from exon 7 skipping caused by 5â²-splice site mutation of human cathepsin A gene
Keywords: bp; base pair(s); cDNA; complementary DNA; CTSA; cathepsin A; EGFP; enhanced green fluorescent protein; kbp; kilobase pairs; kDa; kilodaltons; PAGE; polyacrylamide gel electrophoresis; PCR; polymerase chain reaction; pre-mRNA; mRNA precursor; rAAV; recomb
The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach
Keywords: COPD; Chronic obstructive pulmonary disease; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated Protein 9 (Cas9); CSC; Cigarette smoke co
Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs
Keywords: apolipoprotein E; atherosclerosis; pig; remnant cholesterol dysbetalipoproteinemia; APOB; apolipoprotein B; APOE; apolipoprotein E; cDNA; complementary DNA; HFHC; high-fat high-cholesterol; IDL; intermediate-density lipoprotein; LAD; left anterior descend
Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium
Keywords: angiogenesis; chronic myocardial ischemia; gene therapy; thymosin β4; Ang; angiopoietin; c/hpf; capillaries per high power field; db; diabetic; LV; left ventricular; miR; microribonucleic acid; p/hpf; pericytes per high power field; rAAV; recombinant ad
Functional integration of complex miRNA networks in central and peripheral lesion and axonal regeneration
Keywords: AAV(s); adeno-associated virus(es); ADAM; a disintegrin and metalloprotease; AGO(2); argonaut (2); AKT; protein kinase B; APC; adenomatous polyposis coli; ASO(s); antisense oligonucleotide(s); ATF3; activating transcription factor 3; BBB; blood brain barr
Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS
Keywords: ALS; amyotrophic lateral sclerosis; IT; intrathecal; rAAV; recombinant adeno-associated virus; CNS; central nervous system; DRG; dorsal root ganglia; IV; intravenous; qPCR; quantitative Polymerase Chain Reaction; DH; dorsal horn; PF; posterior funiculus;
Controlled release strategies for rAAV-mediated gene delivery
Keywords: Human gene therapy; rAAV; Controlled release;
Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery
Keywords: HD; Huntington's disease; mHTT; mutant Huntingtin; rAAV; recombinant Adeno Associated Virus; LV; lentivirus; tNAA; total N-Acetyl Aspartate; Myo-Ins; myoinositol; GFP; green fluorescent protein; NeuN; neuronal nuclei; DARPP-32; dopamine- and cyclic AMP-re
Ambient GABA modulates septo-hippocampal inhibitory terminals via presynaptic GABAb receptors
Keywords: GABAb receptor; Septo-hippocampal pathway; Presynaptic inhibition; Ambient GABA; Medial septum; GABAbR; GABAb receptor; SH-GABA; septo-hippocampal GABAergic pathway; PPr; paired-pulse ratio; rAAV; recombinant adeno-associated virus; ChR2; channelrhodopsin
The atypical 'b' splice variant of phospholipase Cβ1 promotes cardiac contractile dysfunction
Keywords: DGKζ; diacylglycerol kinase ζ; FS; fractional shortening; LVIDd; left ventricular internal diameter at diastole; LVIDs; left ventricular internal diameter at systole; LVPWd; left ventricular posterior wall thickness at diastole; LVPWs; left ventricular
ReviewThe relation between α-synuclein and microglia in Parkinson's disease: Recent developments
Keywords: CSF; cerebrospinal fluid; FcgR; Fc gamma receptors; HO-1; heme oxygenase-1; IgG; immunoglobulin G; LPS; lipopolysaccharide; Nrf2; NF-E2-related factor 2; PD; Parkinson's disease; PET; positron emission tomography; rAAV; recombinant adeno-associated vira
Effective genetic modification and differentiation of hMSCs upon controlled release of rAAV vectors using alginate/poloxamer composite systems
Keywords: rAAV; recombinant adeno-associated viral vectors; hMSCs; human mesenchymal stem cells; AlgPH155; alginate; PF127; Pluronic F127©; AlgPH155Â +Â PF127 [C]; alginate/PF127 capsules crosslinked at room temperature; AlgPH155Â +Â PF127 [H]; alginate/PF127 caps
Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex
Keywords: rAAV; Tropism; Viral vector; Monkey; Non-human primate; Neuron;
Short communicationComparison of the efficacy of five adeno-associated virus vectors for transducing dorsal raphé nucleus cells in the mouse
Keywords: DRN; dorsal raphé nucleus; eGFP; enhanced green fluorescent protein; rAAV; recombinant adeno-associated virus; TBS; Tris buffered saline; TBS-T; Tris-buffered saline with 0.3% Triton-X-100; Adeno-associated virus; Pseudotype; Transduction; Dorsal raphé
NQO1 involves in the imine bond reduction of sanguinarine and recombinant adeno-associated virus mediated NQO1 overexpression decreases sanguinarine-induced cytotoxicity in rat BRL cells
Keywords: Sanguinarine; NQO1; CYP1A; RAAV; Cytotoxicity;
Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs
Keywords: rAAV; Gene targeting; Homologous recombination; SCNT; Genetically modified pigs
Y5 neuropeptide Y receptor overexpression in mice neither affects anxiety- and depression-like behaviours nor seizures but confers moderate hyperactivity
Keywords: rAAV; Neuropeptide Y; Y5 receptor; Locomotion; Anxiety; Depression; Seizures
CTLA4-FasL fusion product suppresses proliferation of fibroblast-like synoviocytes and progression of adjuvant-induced arthritis in rats
Keywords: RA; rheumatoid arthritis; AIA; adjuvant-induced arthritis; FLSs; fibroblast-like synoviocytes; rAAV; recombinant adeno-associated virus; FasL; Fas ligand; mFasL; mature FasL; sFasL; soluble FasL; AI; articular index; EGFP; enhanced green fluorescent prote
Adult-onset hippocampal-specific neuropeptide Y overexpression confers mild anxiolytic effect in mice
Keywords: Neuropeptide; Anxiety; rAAV; Gene transfer; Behavior
Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain
Keywords: rAAV; recombinant adeno-associated virus; LV; Lenti virus; RMS; rostral migratory stream; Recombinant adeno-associated virus; Lenti virus; Gene transfer, Cre-recombinase; Stereotaxic injection;
Regenerative pharmacology in the treatment of genetic diseases: The paradigm of muscular dystrophy
Keywords: MD; muscular dystrophies; DMD; duchenne muscular dystrophy; DAPC; dystrophin-associated protein complex; DGC; dystrophin-glycoprotein complex; DG; dystroglycans; SCG; sarcoglycans; nNOS; neuronal nitric oxide synthase; NO; nitric oxide; HDAC; histone deac
Cone-specific expression using a human red opsin promoter in recombinant AAV
Keywords: Cone; Gene therapy; Photoreceptors; Promoter; rAAV; Retina; Retinal degeneration
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated α7 nicotinic receptor gene transfer
Keywords: α7; Gene transfer; Nicotinic; rAAV; Hippocampus; 5-hydroxyindole (5-HI); GTS-21; DMXB
Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo
Keywords: rAAV; Striatum; Huntington's disease; Mouse; Gene transfer; Neurological disorder; Genetic disorder;
Gangliosides, Ab1 and Ab2 antibodies: III. The idiotype of anti-ganglioside mAb P3 is immunogenic in a T cell-dependent manner
Keywords: Idiotype; SIP; rAAV; Immunogenicity; Anti-idiotypic antibodies
A new approach to control condylar growth by regulating angiogenesis
Keywords: Angiogenesis; Condylar growth; VEGF; FGF; Angiostatin; Endostatin; Stem cells; rAAV; Craniofacial growth deformities
Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity
Keywords: galanin; epilepsy; gene therapy; rAAV; kindling; synaptic plasticityaCSF, artificial cerebrospinal fluid; AD, afterdischarge; AP, anterior–posterior; CA, cornu ammonis; CMV, cytomegalovirus; DCG-IV, (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine; DG,
α7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation
Keywords: α7 nicotinic receptors; recombinant adeno-associated virus; ACSF; artificial cerebrospinal fluid; AD; Alzheimer's disease; FBS; fetal bovine serum; GFP; green fluorescent protein; gp; genomic particle; KO; knockout; KRH; Krebs Ringer buffer; MLA; methy
Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates CD151-induced endothelial cell proliferation and cell migration
Keywords: eNOS, endothelial nitric-oxide synthase; NO, nitric oxide; PI3K, phosphatidylinositol-3-kinase; HUVEC, human umbilical vein endothelial cell; DMEM, Dulbecco's modified Eagle's medium; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; rAAV
Use of recombinant adeno-associated viral vectors as a tool for labeling bone marrow cells
Keywords: Bone marrow cell; rAAV; Transduction;
A proximal E-box modulates NGF effects on rat PPT-A promoter activity in cultured dorsal root ganglia neurones
Keywords: AAV; adeno-associated virus; rAAV; recombinant adeno-associated virus; AP1; activator protein 1; bHLH; basic helix-loop-helix; DRG; dorsal root ganglion; Luc; luciferase; NGF; nerve growth factor; rtPPT-A; rat preprotachykinin-A; NK1; neurokinin recep
A novel scheme of dystrophin disruption for the progression of advanced heart failure
Keywords: CM; cardiomyopathy; DCM; dilated cardiomyopathy; δ-SG; δ-sarcoglycan; DAP; dystrophin-associated proteins; HCM; hypertrophic cardiomyopathy; LVP; left ventricular pressure; rAAV; recombinant adeno-associated virus; Dystrophin; δ-Sarcoglycan (SG); Gene
A novel paradigm for therapeutic basis of advanced heart failure-assessment by gene therapy
Keywords: Dystrophin (Dys); δ-Sarcoglycan (SG); Gene therapy; Heart failure (HF); Proteolysis; Calpains; A-kinase; cyclic adenosine monophosphate (cAMP)-dependent protein kinase; AMI; acute myocardial infarction; DAP; dystrophin-associated proteins; DCM; dilated c
Gene therapy targeted at calcium handling as an approach to the treatment of heart failure
Keywords: Cardiomyopathy; Heart failure; Gene therapy; Phospholamban; Calcium ATPase; Sarcoplasmic reticulum; AC; adenylyl cyclase; AR; adrenergic receptor; βARKct; C-terminal inhibitory β-adrenergic receptor (βAR) kinase fragment; CaMKII; calcium/calmodulin-dep