Telomere length modulates human radiation sensitivity in vitro
Keywords: Telomeres; Micronuclei; Radiosensitivity
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Enhanced radiation-induced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNA damage via activation of ATM pathways
Keywords: 2-ME; Radiosensitivity; Glioma cell; Apoptosis; T98G cell; U251MG cell
Haplotype-Based Analysis of Genes Associated With Risk of Adverse Skin Reactions After Radiotherapy in Breast Cancer Patients
Keywords: Radiosensitivity; Single nucleotide polymorphism; SNP; Haplotype; Early adverse skin reaction;
Sensing radiosensitivity of human epidermal stem cells
Keywords: Keratinocyte; Stem cells; Progenitors; Human epidermis; Radiosensitivity; Ionizing radiation; Transcriptome; Microarrays
Radiation sensitivity of leukocytes from healthy individuals and breast cancer patients as measured by the alkaline and neutral comet assay
Keywords: Comet assay; Breast cancer patients; Radiosensitivity; Leukocytes; DNA damage
A case report of a patient with microcephaly, facial dysmorphism, chromosomal radiosensitivity and telomere length alterations closely resembling “Nijmegen breakage syndrome” phenotype
Keywords: NBS; NBS-like; Chromosomal instability syndromes; Radiosensitivity; Congenital microcephaly
Metabolic functional imaging for tumor radiosensitivity monitoring
Keywords: Radiosensitivity; PET; Radiation therapy; Tumor response; Nuclear imaging
Cell Kinetics
Keywords: Accelerated fractionation; cell cycle; cell kinetics; proliferation; radiosensitivity; repopulation;
Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation
Keywords: HAT, histone acetyltransferase; HDAC, histone deacetylase; SER, sensitizer enhancement ratioATM; Anacardic acid; Tip60; HAT; Radiosensitivity; DNA repair
Early determination of uterine cervical squamous cell carcinoma radioresponse identifies high- and low-response tumors
Keywords: Radiosensitivity; Intracavitary radiotherapy; Minimum target dose; Chemoradiotherapy;
The effect of p21 antisense oligodeoxynucleotides on the radiosensitivity of nasopharyngeal carcinoma cells with normal p53 function
Keywords: P21; Antisense oligodeoxynucleotides; Radiosensitivity; Nasopharyngeal carcinoma;
Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity
Keywords: Glioblastoma; Radiation therapy; Ionizing radiation; ATM; Methylation; Radiosensitivity
Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation
Keywords: Colony-forming assay; DNA damage; Double-strand breaks; Histone γH2AX; Radiosensitivity;
Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells
Keywords: Survivin; Radiosensitivity; Antisense oligonucleotide;
Individual radiation response of parotid glands investigated by dynamic 11C-methionine PET
Keywords: IMRT; Xerostomia; Radiosensitivity; Radiobiology; Parotid sparing RT
HIV-1 Tat depresses DNA-PKCS expression and DNA repair, and sensitizes cells to ionizing radiation
Keywords: HIV-1 Tat; DNA-PKcs; DNA repair; Cell cycle arrest; Radiosensitivity;
Wound healing morbidity in STS patients treated with preoperative radiotherapy in relation to in vitro skin fibroblast radiosensitivity, proliferative capacity and TGF-β activity
Keywords: Fibroblasts; Radiosensitivity; Proliferation; TGF-β; Wound healing
Human keratinocyte radiosensitivity is linked to redox modulation
Keywords: Skin; Keratinocyte; Oxidative stress; Apoptosis; Radiosensitivity; Ionising radiation
Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status
Keywords: Hypoxia; Radiosensitivity; DNA repair; Homologous recombination; Foci;
Radiobiology of Breast Cancer
Keywords: Breast cancer; DNA repair; fractionation; normal tissues; radiosensitivity; radiotherapy;
Glycerol enhances radiosensitivity in a human oral squamous cell carcinoma cell line (Ca9-22) bearing a mutant p53 gene via Bax-mediated induction of apoptosis
Keywords: Oral squamous cell carcinoma; Apoptosis; Glycerol; p53; Radiosensitivity;
Potential application of the ATP cell viability assay in the measurement of intrinsic radiosensitivity in cervical cancer
Keywords: ATP cell viability assay; Cervical cancer; Radiosensitivity;
Post-irradiation phosphorylation of structural maintenance chromosome 1 (SMC1) is independent of the Fanconi protein pathway
Keywords: Fanconi anemia; Radiosensitivity; Ataxia-telangiectasia mutated; Structural maintenance chromosome 1; Colony survival assay;
Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin
Keywords: Cofilin; Radiosensitivity; DNA repair capacity; Comet assays;
The two edges of the ATM sword: Co-operation between repair and checkpoint functions
Keywords: DNA double strand breaks; Signal transduction; Ionising radiation; Radiosensitivity; Ataxia telangiectasia; Artemis;
Inter-strain variance in late phase of erythematous reaction or leg contracture after local irradiation among three strains of mice
Keywords: Ionizing radiation; Radiosensitivity; Experimental radiation injuries; Mice, inbred strains; Mice, inbred C57BL; Mice, inbred C3H; Mice, inbred A; cDNA microarrays; RT-PCR; Erythematous reaction; Leg contracture; Genetic factor; Gene expression; Microarra
Apoptotic index as predictive marker for radiosensitivity of cervical carcinoma: Evaluation of membrane fluidity, biochemical parameters and apoptosis after the first dose of fractionated radiotherapy to patients
Keywords: Apoptotic index; Enzymatic antioxidants; Predictive assay and radiotherapy; Uterine cervical carcinoma; Membrane fluidity; Calcium signalling; Radiosensitivity; Apoptosis; Superoxide dismutase; Glutathione peroxidase; Antioxidant enzymes; Predictive marke
Les oligodendrogliomes cérébraux de l'adulte et de l'enfant
Keywords: oligodendrogliomas; chemotherapy; chemosensitivity; radiotherapy; radiosensitivity; radiosurgery; tumor removal; molecular biology; TEP;
Radiostability of pharmaceuticals under different irradiation conditions
Keywords: Gamma irradiation; Electron-beam irradiation; Radiosensitivity; Cefazolin; Glucagon; Dobutamine HCl; Pharmaceuticals; Radiosterilization;
The influence of concentration of DNA on the radiosensitivity of mammalian cells
Keywords: Mammalian cells; DNA concentration; Radiosensitivity;
Potentiation of the radiation effect with genistein in cervical cancer cells
Keywords: Cervical cancer; Radiosensitivity; Genistein;
The Caenorhabditis elegans FancD2 ortholog is required for survival following DNA damage
Keywords: DNA damage response; C. elegans; Fanconi; Radiosensitivity; Crosslinking agent; Survival; RNAi; Genetic disease;
Synergistic cytotoxic effects of zoledronic acid and radiation in human prostate cancer and myeloma cell lines
Keywords: Bisphosphonates; C4-2 cells (prostate cancer cell line); Combination of zoledronic acid and radiotherapy; IM-9 cells (myeloma cell line); Radiosensitivity; Synergism; Zoledronic acid;
Effects of estradiol and progesterone on the variability of the micronucleus assay
Keywords: Radiosensitivity; MN-assay; Estradiol; Progesterone; Lymphocytes;
Monoclonal antibody to HER-2/neu receptor enhances radiosensitivity of esophageal cancer cell lines expressing HER-2/neu oncoprotein
Keywords: Esophageal cancer; Radiosensitivity; Trastuzumab; HER-2/neu;
Regional differences in radiosensitivity across the rat cervical spinal cord
Keywords: Dose-volume effects; Protons; Radiosensitivity; Spinal cord; White matter necrosis;
Bases génétiques de la radiosensibilité des cancers du sein
Keywords: Cancer du sein; Génétique; Radiosensibilité; Breast cancer; Genetics; Radiosensitivity;
Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1α (HIF-1α)
Keywords: Tumor microenvironment; Tumor hypoxia; Radiosensitivity; Hypoxia markers; Hypoxia-inducible factor-1α;