کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9876383 1533549 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Radiostability of pharmaceuticals under different irradiation conditions
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم تشعشع
پیش نمایش صفحه اول مقاله
Radiostability of pharmaceuticals under different irradiation conditions
چکیده انگلیسی
In this paper, the products studied are cefazolin, glucagon and dobutamine HCl. The radioresistance of pharmaceuticals may depend on the conditions of irradiation. The best is to irradiate the drugs in solid state and the chemical transformations can be reduced also by lowering the temperature of the liquid. In solid state, the dose rate has no influence on the decomposition for the selected molecules and it should be noted that drug excipients selected for bioavailability reasons are not always radioprotectors. These results are important from a technical point of view in pharmaceutical industry.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiation Physics and Chemistry - Volume 72, Issues 2–3, February 2005, Pages 355-361
نویسندگان
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